Identification of flavonol and triterpene glycosides in Luo-Han-Guo extract using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry

Journal of Food Composition and Analysis

Volumn 25, Issue 2, 2012, Pages 142-148

  Zhang, Hongyang ^a   Yang, Huihua ^b   Zhang, Min ^a   Wang, Yuerong ^a   Wang, Jingrong ^c   Yau, Leefong ^c   Jiang, Zhihong ^c   Hu, Ping ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b GUILIN UNIVERSITY OF ELECTRONIC TECHNOLOGY   (China)

^c MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Macao)

Author keywords

Flavonol and triterpene glycosides; Food analysis; Food composition; Growing periods; LC MS; Liquid chromatography mass spectrometry; Luo Han Guo; Principle component analysis; Siraitia grosvenorii; Ultra high performance liquid chromatography quadrupole time of flight mass spectrometry

Indexed keywords

SIRAITIA GROSVENORII;

EID: 84857797336     PISSN: 08891575     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfca.2011.09.004     Document Type: Article

References (21)

1. Akihisa T., Hayakawa Y., Tokuda H., Banno N., Shimizu N., Suzuki T., Kimura Y. Cucurbitane glycosides from the fruits of Siraitia grosvenorii and their inhibitory effects on Epstein-Barr virus activation. Journal of Natural Products 2007, 70(5):783-788.
2. DNP, 2010. Available at: (accessed on August 2010). http://dnp.chemnetbase.com/.
3. Kasai R., Nie R.L., Nashi K., Ohtani K., Zhou J., Tao G.D., Tanaka O. Sweet cucurbitane glycosides from fruits of Siraitia siamensis (chi-zi luo-han-guo), a Chinese folk medicine. Agricultural and Biological Chemistry 1989, 53(12):3347-3349.
4. Li D.P., Ikeda T., Matsuoka N., Nohara T., Zhang H.R., Sakamoto T., Nonaka G.I. Cucurbitane glycosides from unripe fruits of Lo Han Kuo (Siraitia grosvenorii). Chemical and Pharmaceutical Bulletin 2006, 54(10):1425-1428.
5. Li D.P., Ikeda T., Huang Y.L., Liu J.L., Nohara T., Sakamoto T., Nonaka G.I. Seasonal variation of mogrosides in Lo Han Kuo (Siraitia grosvenorii) fruits. Journal of Natural Medicines 2007, 61(3):307-312.
6. Li D.P., Ikeda T., Nohara T., Liu J.L., Wen Y.X., Sakamoto T., Nonaka G.I. Cucurbitane glycosides from unripe fruits of Siraitia grosvenorii. Chemical and Pharmaceutical Bulletin 2007, 55(7):1082-1086.
7. Liu J.L., Li D.P., Huang Y.L., Lu H.X. Determination of mogrol glycosides from fruits of Siraitia grosvenorii in different growing ages by HPLC. Guihaia 2007, 27(4):665-668.
8. Lu F.L., Liu J.L., Huang Y.L., Li D.P. Simultaneous determination of six cucurbitane triterpene glycosides in Siraitia grosvenorii fruits using high performance liquid chromatography. Chinese Journal of Chromatography 2008, 26(4):504-508.
9. Si J.Y., Chen D.H., Chang Q., Shen L.G. Isolation and structure determination of flavonol glycosides from the fresh fruits of Siraitia grosvenorii. Acta Pharmaceutica Sinica 1994, 29(2):158-160.
10. Suzuki Y.A., Murata Y., Inui H., Sugiura M., Nakano Y. Ttiterpene glycosides of Siraitia grosvenorii inhibit rat intestinal maltase and suppress the rise in blood glucose level after a single oral administration of maltose in rats. Journal of Agricultural and Food Chemistry 2005, 53(8):2941-2946.
11. Takasaki M., Konoshima T., Murata Y., Sugiura M., Nishino H., Tokuda H., Matsumoto K., Kasai R., Yamasaki K. Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenorii. Cancer Letters 2003, 198(1):37-42.
12. Takeo E., Yoshida H., Tada N., Shingu T., Matsuura H., Murata Y., Yoshikawa S., Ishikawa T., Nakamura H., Ohsuzu F., Kohda H. Sweet elements of Siraitia grosvenorii inhibit oxidative modification of low-density lipoprotein. Journal of Atherosclerosis and Thrombosis 2002, 9(2):114-120.
13. The Pharmacopoeia Commission of PRC The Pharmacopoeia of the People's Republic of China: Part I 2005, Chemical Industry Publishing Press, Beijing, China, pp. 147-148.
14. Ukiya M., Akihisa T., Tokuda H., Toriumi M., Mukainaka T., Banno N., Kimura Y., Hasegawa J., Nishino H. Inhibitory effects of cucurbitane glycosides and other triterpenoids from the fruit of Momordica grosvenorii on epstein-barr virus early antigen induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Journal of Agricultural and Food Chemistry 2002, 50(23):6710-6715.
15. Xia Y., Rivero-Huguet M.E., Hughes B.H., Marshall W.D. Isolation of the sweet components from Siraitia grosvenorii. Food Chemistry 2008, 107(3):1022-1028.
16. Yang B.R., Halttunen T., Raimo O., Price K., Kallio H. Flavonol glycosides in wild and cultivated berries of three major subspecies of Hippophae rhamnoides and changes during harvesting period. Food Chemistry 2009, 115(2):657-664.
17. Zhang J., Jin Y., Dong J., Xiao Y.S., Feng J.T., Xue X.Y., Zhang X.L., Liang X.M. Systematic screening and characterization of tertiary and quaternary alkaloids from corydalis yanhusuo W.T. Wang using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. Talanta 2009, 78(2):513-522.
18. Zhou J.L., Qi L.W., Li P. Herbal medicine analysis by liquid chromatography/time-of-flight mass spectrometry. Journal of Chromatography A 2009, 1216(44):7582-7594.
19. Zhou J.L., Xin G.Z., Shi Z.Q., Ren M.T., Qi L.W., Li H.J., Li P. Characterization and identification of steroidal alkaloids in Fritillaria species using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Journal of Chromatography A 2010, 1217(45):7109-7122.
20. Zhou W., Su S.L., Duan J.A., Guo J.M., Qian D.W., Shang E.X., Zhang J. Characterization of the active constituents in Shixiao San using bioactivity evaluation followed by UPLC-QTOF and Markerlynx analysis. Molecules 2010, 15(9):6217-6230.
21. Zhou Y., Xu G., Choi F.F.K., Ding L.S., Han Q.B., Song J.Z., Qiao C.F., Zhao Q.S., Xu H.X. Qualitative and quantitative analysis of diterpenoids in Salvia species by liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Journal of Chromatography A 2009, 1216(24):4847-4858.