Determination of conjugated and free isoflavones in some legumes by LC-MS/MS

Journal of Food Composition and Analysis

Volumn 25, Issue 2, 2012, Pages 173-178

  Konar, Nevzat ^a   Poyrazoĝlu, Ender Sinan ^a   Demir, Köksal ^a   Artik, Nevzat ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Bean; Chickpea; Food analysis; Food composition; Free and conjugated isoflavones; LC MS MS; Legumes; Lentil; Phytoestrogens

Indexed keywords

CICER ARIETINUM; LENS CULINARIS; PHASEOLUS VULGARIS;

EID: 84857795140     PISSN: 08891575     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfca.2011.11.004     Document Type: Article

References (28)

1. Alves R.C., Almeida I.M.C., Casal S., Oliveria M.B.P.P. Method development and validation for isoflavones quantification in coffee. Food Chemistry 2010, 122:914-919.
2. Araújo J.M.A., Silva M.S., Chaves J.B.P. Supercritical fluid extraction of daidzein and genistein isoflavones from soybean hypocotyl after hydrolysis with endogenous β-glucosidases. Food Chemistry 2007, 105(1):266-272.
3. Barnes K.A., Smith R.A., Williams K., Damant A.P., Shepherd M.J. A microbore high performance liquid chromatography/electrospray ionization mass spectrometry method for the determination of the phytoestrogens genistein and daidzein in comminuted baby foods and soya flour. Rapid Communications in Mass Spectrometry 1998, 12:130-138.
4. Boniglia C., Carratù B., Gargiulo R., Giammarioli S., Mosca M., Sanzini E. Content of phytoestrogens in soy-based dietary supplements. Food Chemistry 2009, 115:1389-1392.
5. Branham W.S., Dial S.L., Moland C.L., Hass B.J., Blair R.M., Fang H. Phytoestrogens and mycoestrogens bind to the rat uterine estrogen receptor. Journal of Nutrition 2002, 132(4):658-664.
6. Clarke D.B., Bailey V., Lloyd A.S. Determination of phytoestrogens in dietary supplements by LC-MS/MS. Food Additives and Contaminants 2008, 25(5):534-547.
7. Coward L., Barnes N.C., Setchell K.D.R., Banes S. Genistein and daidzein, and their β-glycoside conjugates: anti-tumor isoflavones in soybean foods from American and Asia diets. Journal of Agricultural and Food Chemistry 1993, 41:1961-1967.
8. Espin J.C., Garcisa-Conesa M.T., Tomas-Barberan F.A. Nutraceuticals: facts and fiction. Phytochemistry 2007, 67:2986-3008.
9. Fukutake M., Takahashi M., Ishida K., Kawamura K., Sugimura T., Wakabayashi K. Quantification of genistein and genistin in soybeans and soybean products. Food and Chemical Toxicology 1996, 34:457-461.
10. Howes L.G., Howes J.B., Knight D.C. Isoflavone therapy for menopausal flushes: a systematic review and meta-analysis. Maturitas 2006, 55:203-211.
11. Ikeda Y., Iki M., Morita A., Kajita E., Kagamimori S., Kagawa Y., Yoneshima H. Intake of fermented soybeans, natto, is associated with reduced bone loss in postmenopausal women: Japanese population-based osteoporosis (JPOS) study. Journal of Nutrition 2006, 136:1323-1328.
12. Kalogeropoulos N., Chiou A., Ioannou M., Karathanos V.T., Hassapidou M., Andrikopoulus N.K. Nutritional evaluation and bioactive microconstituents (phytosterols, tocopherols, polyphenols, triterpenic acids) in cooked dry legumes usually consumed in the Mediterranean countries. Food Chemistry 2010, 121:682-690.
13. Kim J., Hong S., Jung W., Yu C., Ma K., Gwag J., Chung I. Comparison of isoflavones composition in seed, embryo, cotyledon and seed coat of cooked-with-rice and vegetable soybean (Glycine max L.) varieties. Food Chemistry 2007, 102:738-744.
14. Kuhnle G.G.C., Dell'Aquila C., Low Y.L., Kussmaul M., Bingham S.A. Extraction and quantification of phytoestrogens in foods using automated solid-phase extraction and LC/MS/MS. Analytical Chemistry 2007, 79:9234-9239.
15. Kuhnle G.G.C., Dell'Aquila C., Runswick S.A., Bingham S. Variability of phytoestrogen content in foods from different sources. Food Chemistry 2009, 113:1184-1187.
16. 13C-labelled standarts. Food Chemistry 2009, 116:542-554.
17. Lee J.H., Park C.H., Jung K.C., Rhee H.S., Yang C.H. Negative regulation of beta- catenin/Tcf signaling by naringenin in AGS gastric cancer cell. Biochemical and Biophysical Research Communications 2005, 335(3):771-776.
18. Liggins J., Bluck L.J.C., Runswick S., Atkinsok C., Coward W.A., Bingham S.A. Daidzein and genistein contents of vegetables. British Journal of Nutrition 2000, 84:717-725.
19. Mazur W.M., Duke J.A., Wahala K., Rasku S., Adlercreutz H. Isoflavonoids and lignans in legumes: nutritional and health aspects in humans. Nutritional Biochemistry 1998, 9:193-200.
20. Müllner C., Sontag G. Determination of some phytoestrogens in soybeans and their processed products with HPLC and coulometric electrode array detection. Fresenius Journal of Analytical Chemistry 1999, 364:261-265.
21. Otieno D.O., Ashton J.F., Shah N.P. Isoflavone phytoestrogen degradation in fermented soymilk with selected β-glucosidase producing L. Acidophilus strains during storage at different temperatures. International Journal of Food Microbiology 2007, 115:79-88.
22. Riu A., Palagwer P., Perdu E., Pandelova M., Piccinelli R., Gustafsson J.A., Leckerq C., Schramm K.W., Dagnino S., Debrauwer L., Cravedi J.-P., Zalko D. Characterisation of bioactive compounds in infant formulas using immobilised recombinant estrogen receptor-α affinity columns. Food and Chemical Toxicology 2008, 46:3268-3278.
23. Rostagno M.A., Villares A., Guillamon E., Garcia-Lafuente A., Martinez J.A. Sample preparation for the analysis of isoflavones from the soy beans and soy foods. Journal of The Chromatography A 2009, 1216:2-29.
24. Setchell K.D.R. Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones. American Journal of Clinical Nutrition 1998, 68:1333S-1346S.
25. Taylor J.I., Grace P.B., Bingham S.A. Optimization of conditions for the enzymatic hydrolysis of phytoestrogen conjugates in urine and plasma. Analytical Biochemistry 2005, 341:220-229.
26. Verheus M., van Gils C.H., Keinan-Boker L., Grace P.B., Bingham S.A., Peeters P.H.M. Plasma phytoestrogens and subsequent breast cancer risk. Journal of Clinical Oncology 2007, 25:648-655.
27. Ward H.A., Kuhnle G.G.C. Phytoestrogen consumption and association with breast, prostate and colorectal cancer in EPIC Norfolk. Archives of Biochemistry 2010, 501:170-175.
28. Williamson-Hughes P.S., Flickinger B.D., Messina M.J., Empie .W. Isoflavone supplements containing predominantly genistein reduce hot flash symptoms: a critical review of published articles. Menopause - the Journal of the North American Menopause Society 2006, 13:831-839.