Microparticle systems based on polymer-drug interaction for ocular delivery of ciprofloxacin I. In vitro characterization

Journal of Drug Delivery Science and Technology

Volumn 17, Issue 1, 2007, Pages 57-62

  Bonferoni, M C ^a   Sandri, G ^a   Gavini, E ^b   Rossi, S ^a   Ferrari, F ^a   Caramella, C ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF SASSARI   (Italy)

Author keywords

Chondroitin sulphate; Ciprofloxacin; Ionic interaction; Microparticles; Mucoadhesion; Ophthalmic delivery

Indexed keywords

BLANOSE; CARBOMER; CARBOXYMETHYLCELLULOSE; CHONDROITIN 6 SULFATE; CIPROFLOXACIN; GELATIN; GENERIC DRUG; HYDROXYPROPYLCELLULOSE; OFTACILOX; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONJUNCTIVA; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ADSORPTION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; FLOW KINETICS; LACRIMAL FLUID; MOLECULAR INTERACTION; NONHUMAN; PARTICLE SIZE; PH MEASUREMENT; SHEAR RATE; SWINE; TEAR FLOW;

EID: 33847363962     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(07)50008-0     Document Type: Article

References (17)

1. Zimmer A., Kreuter J. - Microspheres and nanoparticles used in ocular delivery systems. - Adv. Drug. Del. Rev., 16, 61-73, 1995.
2. Giunchedi P., Conte U., Chetoni P., Saettone M.F. - Pectin microspheres as ophthalmic carriers for piroxicam: evaluation in vitro and in vivo in albino rabbits. - Eur. J. Pharm Sci., 9, 1-7, 1999.
3. Genta I., Conti B., Perugini P., Pavanetto F., Spadaro A., Puglisi G. . Bioadhesive microspheres for ophthalmic administration of acyclovir. J. Pharm. Pharmacol., 49, 737-742, 1997.
4. Durrani A.M., Farr S.J., Kellaway I.W.. Precorneal clearance of mucoadhesive microspheres from the rabbit eye. J. Pharm. Pharmacol., 47, 581-584, 1995.
5. Jani R., Gan O., Ali Y., Rodstrom R., Hancock S. - Ion exchange resins for ophthalmic delivery. - J. Ocular Pharmacol., 10, 57-67, 1994.
6. Jani R., Harris R. - Sustained release, comfort formulations for glaucoma therapy. - US Patent, 4, 911,920, 1990.
7. Zimmer A.K., Chetoni P., Saettone M.F., Zerbe H., Kreuter J. - Evaluation of pilocarpine-loaded albumin particles as controlled drug delivery systems for the eye. - J. Controlled Rel., 33, 31-46, 1995.
8. Bonferoni M.C., Chetoni P., Giunchedi P., Rossi S., Ferrari F., Burgalassi S., Caramella C. - Carrageenan-gelatin mucoadhesive systems for ihon exchange based ophthalmic delivery: in vitro and preliminary in vivo studies. - Eur. J. Pharm. and Biopharm,. 57, 465-472, 2004
9. Di Colo G., Zambito Y., Burgalassi S., Nardini I., Saettone M.F. - Effect of chitosan and N-carboxymethylchitosan on intraocular pemetration of topically applied ofloxacin. - Int. J. Pharm., 273, 37-44, 2004.
10. Lele B.S., Hoffman A.S. - Insoluble complexes of polyacrylic acid with a cationic drug for use as a mucoadhesive, ophthalmic drug delivery system. - J. Biomater. Sci. Polym. Ed., 11, 1319-1331, 2000.
11. Parks D.J., Abrams D.A., Sarfarazi F.A., Katz H.R. - Comparison of topical ciprofloxacin conventional antibiotic therapy in the treatment of ulcerative keratitis. - Am. J. Ophthalmol., 115, 471-477, 1993.
12. Firestone B.A., Dickason M.A., Tran T. - Solubility characteristics of three fluoroquinolone ophthalmic solutions in an vitro tear model. - Int. J. Pharm., 164, 119-128, 1998.
13. Cho K. J., Chung T.W., Kim B.C., Kim M.K., Lee J.H., Wee W.R., Cho C.S. - Release of ciprofloxacin from poloxamer-graft-hyaluronic acid hydrogels in vitro. - Int. J. Pharm., 260, 83-91, 2003
14. Sintzel M.B., Bernatchez S.F., Tabatabay C., Gurny R. - Biomaterials in ophthalmic drug delivery. - Eur. J. Pharm. Biopharm., 42, 358-374, 1996.
15. Albasini M., Ludwig A. - Evaluation of polysaccharides intended for ophthalmic use in ocular dosage forms. - Il Farmaco, 50, 633-642, 1995.
16. Cuna M., Vila Jato J.L., Torres D. - Controlled-release liquid suspensions based on ion-exchange particles entrapped within acrylic microcapsules. - Int. J. Pharm., 199, 151-158, 2000.
17. Ferrari F., Rossi S., Bonferoni M.C., Bertoni M., Caramella C. - Sensitivity to rate of stress application of different mucoadhesive polymers. - Int. J. Pharm. Adv., 1, 27-37, 1995.