Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 9, 2012, Pages 3422-3427

  Kubinak, Jason L ^a   Ruff, James S ^a   Hyzer, Cornelius Whitney ^a   Slev, Patricia R ^b   Potts, Wayne K ^a  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Antibiotic resistance; Endangered species; Host pathogen; Pathogen escape of adaptive immunity

Indexed keywords

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ERYTHROBLAST; EVOLUTION; EVOLUTIONARY ADAPTATION; FEMALE; FITNESS; GENETIC VARIABILITY; GENOTYPE; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MAMMAL; MOUSE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS VIRULENCE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANIMALS, CONGENIC; EVOLUTION, MOLECULAR; FEMALE; FRIEND MURINE LEUKEMIA VIRUS; GENETIC FITNESS; GENETIC VARIATION; HOST-PATHOGEN INTERACTIONS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED BALB C; PROVIRUSES; RETROVIRIDAE INFECTIONS; SELECTION, GENETIC; SPLENOMEGALY; TUMOR VIRUS INFECTIONS; VIRAL LOAD; VIRULENCE; VIRUS INTEGRATION; VIRUS REPLICATION;

MAMMALIA; VERTEBRATA;

EID: 84857774089     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1112633109     Document Type: Article

References (34)

1. Robinson J, et al. (2011) The IMGT/HLA database. Nucleic Acids Res 39(Database issue): D1171-D1176.
2. Apanius V, Penn D, Slev PR, Ruff LR, Potts WK (1997) The nature of selection on the major histocompatibility complex. Crit Rev Immunol 17:179-224. (Pubitemid 27161351)
3. Penn D, Potts W (1999) The evolution of mating preferences and major histocompatibility genes. Am Nat 153(2):145-164. (Pubitemid 29139433)
4. Spurgin LG, Richardson DS (2010) How pathogens drive genetic diversity: MHC, mechanisms and misunderstandings. Proc Biol Sci 277:979-988.
5. Milinski M (2006) The major histocompatibility complex, sexual selection, and mate choice. Annu Rev Ecol Evol Syst 37:159-186.
6. Takahata N, Nei M (1990) Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci. Genetics 124:967-978. (Pubitemid 20146073)
7. De Boer RJ, Borghans JAM, van Boven M, Kesxmir C, Weissing FJ (2004) Heterozygote advantage fails to explain the high degree of polymorphism of the MHC. Immunogenetics 55:725-731. (Pubitemid 38316677)
8. Piertney SB, Oliver MK (2006) The evolutionary ecology of the major histocompatibility complex. Heredity (Edinb) 96:7-21.
9. Borghans JA, Beltman JB, De Boer RJ (2004) MHC polymorphism under host-pathogen coevolution. Immunogenetics 55:732-739. (Pubitemid 38316678)
10. Haldane JBS (1949) Disease and evolution. Ric Sci 19 (Suppl A):68-75.
11. Potts WK, Slev PR (1995) Pathogen-based models favoring MHC genetic diversity. Immunol Rev 143:181-197.
12. Ayala FJ, Campbell CA (1974) Frequency-dependent selection. Annu Rev Ecol Syst 5: 115-138.
13. McClelland EE, Penn DJ, Potts WK (2003) Major histocompatibility complex heterozygote superiority during coinfection. Infect Immun 71:2079-2086. (Pubitemid 36368742)
14. Ebert D, Hamilton WD (1996) Sex against virulence: The coevolution of parasitic diseases. Trends Ecol Evol 11:79-82.
15. Hamilton WD, Axelrod R, Tanese R (1990) Sexual reproduction as an adaptation to resist parasites (a review). Proc Natl Acad Sci USA 87:3566-3573.
16. Murphy KP, Travers P, Janeway C, WalportM(2008) Immunobiology (Garland Science, NY).
17. Cooke GS, Hill AV (2001) Genetics of susceptibility to human infectious disease. Nat Rev Genet 2:967-977. (Pubitemid 33691093)
18. McMichael AJ, Rowland-Jones SL (2001) Cellular immune responses to HIV. Nature 410:980-987. (Pubitemid 32335849)
19. Furukawa Y, Kubota R, Tara M, Izumo S, Osame M (2001) Existence of escape mutant in HTLV-I tax during the development of adult T-cell leukemia. Blood 97:987-993. (Pubitemid 32162077)
20. Erickson AL, et al. (2001) The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes. Immunity 15: 883-895. (Pubitemid 34075370)
21. Paterson S, et al. (2010) Antagonistic coevolution accelerates molecular evolution. Nature 464:275-278.
22. Berenos C, Wegner KM, Schmid-Hempel P (2011) Antagonistic coevolution with parasites maintains host genetic diversity: An experimental test. Proc Biol Sci 278: 218-224.
23. McClelland EE, Adler FR, Granger DL, Potts WK (2004) Major histocompatibility complex controls the trajectory but not host-specific adaptation during virulence evolution of the pathogenic fungus Cryptococcus neoformans. Proc Biol Sci 271: 1557-1564. (Pubitemid 38998755)
24. Friedrich TC, et al. (2004) Reversion of CTL escape-variant immunodeficiency viruses in vivo. Nat Med 10:275-281. (Pubitemid 38667618)
25. Friend C (1957) Cell-free transmission in adult Swiss mice of a disease having the character of a leukemia. J Exp Med 105:307-318.
26. Ebert D (1998) Experimental evolution of parasites. Science 282:1432-1435.
27. Slev PR, Potts WK (2002) Disease consequences of pathogen adaptation. Curr Opin Immunol 14:609-614.
28. Metcalf D, Furth J, Buffett RF (1959) Pathogenesis of mouse leukemia caused by Friend virus. Cancer Res 19:52-58.
29. Li JP, D'Andrea AD, Lodish HF, Baltimore D (1990) Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor. Nature 343:762-764.
30. Grech K, Watt K, Read AF (2006) Host-parasite interactions for virulence and resistance in a malaria model system. J Evol Biol 19:1620-1630.
31. Wegner KM, Kalbe M, Kurtz J, Reusch TB, Milinski M (2003) Parasite selection for immunogenetic optimality. Science 301:1343. (Pubitemid 37075801)
32. McClelland EE, et al. (2004) Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: Can we trust congenic animals? BMC Immunol 5:14.
33. Angulo FJ, Nargund VN, Chiller TC (2004) Evidence of an association between use of anti-microbial agents in food animals and anti-microbial resistance among bacteria isolated from humans and the human health consequences of such resistance. J Vet Med B Infect Dis Vet Public Health 51:374-379. (Pubitemid 39547739)
34. Frankham R, Ballou JD, Briscoe DA (2002) Conservation Genetics (Cambridge University Press, Cambridge).