Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: Can we trust congenic animals?

BMC Immunology

Volumn 5, Issue , 2004, Pages

  McClelland, Erin E ^a   Damjanovich, Kristy ^a   Gardner, Kyle ^a   Groesbeck, Zack J ^a   Ma, Maggie S ^a   Nibley, Megan ^a   Richardson, Kelly S ^a   Wilkinson, Maureen ^a   Morrison, Linda C ^a   Bernhardt, Paul ^a   Potts, Wayne K ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONGENIC STRAIN; CONTROLLED STUDY; EXPERIMENTAL INFECTION; GENE MUTATION; GENE SEGREGATION; GENETIC DIFFERENCE; GENOTYPE; HOMOZYGOTE; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; MURINE ENCEPHALOMYELITIS VIRUS; NONHUMAN; PHENOTYPE; RECESSIVE GENE; SALMONELLA; STRAIN DIFFERENCE; TITRIMETRY; VIRUS LOAD; WEIGHT REDUCTION; ANIMAL; ANIMAL SALMONELLOSIS; BIOLOGICAL MODEL; C57BL MOUSE; CARDIOVIRUS INFECTION; CROSS BREEDING; FEMALE; GENETIC VARIABILITY; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALE; SALMONELLA TYPHIMURIUM;

H2 ANTIGEN;

ANIMALS; CARDIOVIRUS INFECTIONS; CROSSES, GENETIC; FEMALE; GENETIC VARIATION; GENOTYPE; H-2 ANTIGENS; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MODELS, GENETIC; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM; THEILOVIRUS; WEIGHT LOSS;

EID: 26444477045     PISSN: 14712172     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-5-14     Document Type: Article

References (24)

1. Reifsnyder PC, Flynn JC, Gavin AL, Simone EA, Sharp JJ, Herberg L, Leiter EH: Genotypic and phenotypic characterization of six new recombinant congenic strains derived from NOD/Shi and CBA/J genomes. Mamm Genome 1999, 10:161-167.
2. Weiss S, Uematsu Y, D'Hoostelaere L, Alanen A: Gross genetic differences among substrains of NZB mice. J Immunogenet 1989, 16:217-221.
3. Specht CG, Schoepfer R: Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice. BMC Neurosci 2001, 2:11.
4. Sluyter F, Marican CC, Crusio WE: Further phenotypical characterisation of two substrains of C57BL/6J inbred mice differing by a spontaneous single-gene mutation. Behav Brain Res 1999, 98:39-43.
5. Silver LM: Mouse Genetics: Concepts and Applications. New York, Oxford University Press; 1995:362.
6. Henricks KK, Miner LL, Marley RJ: Differential cocaine sensitivity between two closely related substrains of C57BL mice. Psychopharmacology (Berl) 1997, 132:161-168.
7. Glant TT, Bardos T, Vermes C, Chandrasekaran R, Valdez JC, Otto JM, Gerard D, Velins S, Lovasz G, Zhang J, Mikecz K, Finnegan A: Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice: evidence of genetically acquired resistance to autoimmune disease. Arthritis Rheum 2001, 44:682-692.
8. Teuscher C, Hickey WF, Korngold R: Experimental allergic orchitis in mice. V. Resistance to actively induced disease in BALB/cJ substrain mice is mediated by CD4+ T cells. Immunogenetics 1990, 32:34-40.
9. Mahler M, Bristol IJ, Leiter EH, Workman AE, Birkenmeier EH, Elson CO, Sundberg JP: Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis. Am J Physiol 1998, 274:G544-51.
10. Silvia OJ, Urosevic N: Variations in LPS responsiveness among different mouse substrains of C3H lineage and their congenic derivative sublines. Immunogenetics 1999, 50:354-357.
11. Nicholson SM, Peterson JD, Miller SD, Wang K, Dal Canto MC, Melvold RW: BALB/c substrain differences in susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease. J Neuroimmunol 1994, 52:19-24.
12. Bailey DW: How pure are inbred strains of mice? Immunol Today 1982, 3:210-214.
13. McClelland EE, Penn DJ, Potts WK: Major Histocompatibility Complex Heterozygote Superiority during Coinfection. Infect Immun 2003, 71:2079-2086.
14. Shabalina SA, Yampolsky LYu, Kondrashov AS: Rapid decline of fitness in panmictic populations of Drosophila melanogaster maintained under relaxed natural selection. Proc Natl Acad Sci U S A 1997, 94:13034-13039.
15. Kondrashov AS: Contamination of the genome by very slightly deleterious mutations: why have we not died 100 times over? J Theor Biol 1995, 175:583-594.
16. Wright S: Evolution and the genetics of populations, vol. 2, the theory of gene frequencies. Chicago, University of Chicago Press; 1969.
17. Carroll LS, Potts WK: Accumulated background variation among H2 mutant congenic strains: elimination through PCR-based genotyping of F2 segregants. J Immunol Methods 2001, 257:137-143.
18. Klein J: Natural History of the Histocompatibility Complex. New York, Wiley; 1986.
19. Montag S, Frank M, Ulmer H, Wernet D, Gopel W, Rammensee HG: "Electronic nose" detects major histocompatibility complex-dependent prerenal and postrenal odor components. Proc Natl Acad Sci U S A 2001, 98:9249-9254.
20. Carroll LS, Penn DJ, Potts WK: Discrimination of MHC-derived odors by untrained mice is consistent with divergence in peptide-binding region residues. Proc Natl Acad Sci U S A 2002, 99:2187-2192.
21. Saha BK, Cullen SE: Molecular mapping of murine I region recombinants: crossing over in the E beta gene. J Immunol 1986, 136:1112-1119.
22. Blake JA, Richardson JE, Bult CJ, Kadin JA, Eppig JT: The Mouse Genome Database (MGD): the model organism database for the laboratory mouse. Nucleic Acids Res 2002, 30:113-115.
23. Hormaeche CE, Fahrenkrog MC, Pettifor RA, Brock J: Acquired immunity to Salmonella typhimurium and delayed (footpad) hypersensitivity in BALB/c mice. Immunology 1981, 43:547-554.
24. Kurtz CI, Sun XM, Fujinami RS: Protection of SJL/J mice from demyelinating disease mediated by Theiler's murine encephalomyelitis virus. Microb Pathog 1995, 18:11-27.