The source of moving particles in parafoveal capillaries detected by adaptive optics scanning laser ophthalmoscopy

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 1, 2012, Pages 171-178

  Uji, Akihito ^a   Hangai, Masanori ^a   Ooto, Sotaro ^a   Takayama, Kohei ^a   Arakawa, Naoko ^a   Imamura, Hiroshi ^b   Nozato, Koji ^b   Yoshimura, Nagahisa ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b CANON INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; COMPARATIVE STUDY; ERYTHROCYTE; HUMAN; LEUKOCYTE MICROPARTICLE; NORMAL HUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA CAPILLARY; RETINA CONE; RETINA FOVEA; SCANNING LASER OPHTHALMOSCOPY; VELOCITY; VIDEORECORDING; CAPILLARY; CYTOLOGY; EQUIPMENT DESIGN; LASER; METHODOLOGY; MIDDLE AGED; OPHTHALMOSCOPY; OPTICS; REFERENCE VALUE; REPRODUCIBILITY; RETINA BLOOD VESSEL; VASCULARIZATION;

DIAGNOSTIC AGENT;

ADULT; CAPILLARIES; EQUIPMENT DESIGN; FOVEA CENTRALIS; HUMANS; LASERS; MIDDLE AGED; OPHTHALMOSCOPY; OPTICS AND PHOTONICS; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; RETINAL CONE PHOTORECEPTOR CELLS; RETINAL VESSELS;

EID: 84857756579     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-8192     Document Type: Article

References (43)

1. Schroder S, Palinski W, Schmid-Schonbein GW. Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy. Am J Pathol. 1991;139:81-100.
2. Huang H, Gandhi JK, Zhong X, et al. TNF-α is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis. Invest Ophthalmol Vis Sci. 2011;52:1336-1344.
3. Lutty GA, Cao J, McLeod DS. Relationship of polymorphonuclear leukocytes to capillary dropout in the human diabetic choroid. Am J Pathol. 1997;151:707-714.
4. Nishiwaki H, Ogura Y, Kimura H, Kiryu J, Honda Y. Quantitative evaluation of leukocyte dynamics in retinal microcirculation. Invest Ophthalmol Vis Sci. 1995;36:123-130.
5. Miyamoto K, Ogura Y, Hamada M, et al. In vivo quantification of leukocyte behavior in the retina during endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 1996;37:2708-2715.
6. Miyamoto K, Khosrof S, Bursell SE, et al. Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition. Proc Natl Acad Sci U S A. 1999;96:10836-10841.
7. Miyahara S, Kiryu J, Miyamoto K, et al. Alteration of leukocyteendothelial cell interaction during aging in retinal microcirculation of hypertensive rats. Jpn J Ophthalmol. 2006;50:509-514.
8. Hirose F, Kiryu J, Miyamoto K, et al. In vivo evaluation of retinal injury after transient ischemia in hypertensive rats. Hypertension. 2004;43:1098-1102.
9. Miyamoto K, Hiroshiba N, Tsujikawa A, Ogura Y. In vivo demonstration of increased leukocyte entrapment in retinal microcirculation of diabetic rats. Invest Ophthalmol Vis Sci. 1998;39:2190-2194.
10. Riva CE, Petrig B. Blue field entoptic phenomenon and blood velocity in the retinal capillaries. J Opt Soc Am. 1980;70:1234-1238.
11. Sinclair SH, Azar-Cavanagh M, Soper KA, Tuma RF, Mayrovitz HN. Investigation of the source of the blue field entoptic phenomenon. Invest Ophthalmol Vis Sci. 1989;30:668-673.
12. Grunwald JE, Sinclair SH, Crandall AS, Riva CE. Blue field entoptic phenomenon in amblyopia. Ophthalmology. 1981;88:1054-1057.
13. Loukovaara S, Kaaja R, Immonen I. Macular capillary blood flow velocity by blue-field entoptoscopy in diabetic and healthy women during pregnancy and the postpartum period. Graefes Arch Clin Exp Ophthalmol. 2002;240:977-982.
14. Grunwald JE, Piltz J, Patel N, Bose S, Riva CE. Effect of aging on retinal macular microcirculation: a blue field simulation study. Invest Ophthalmol Vis Sci. 1993;34:3609-3613.
15. Loukovaara S, Harju M, Immonen I. Macular blood flow measured by blue-field entoptoscopy and Heidelberg retinal flowmetry: comparison of two techniques in type 1 diabetes women during pregnancy. Acta Ophthalmol. 2009;87:506-510.
16. Paques M, Boval B, Richard S, et al. Evaluation of fluoresceinlabeled autologous leukocytes for examination of retinal circulation in humans. Curr Eye Res. 2000;21:560-565.
17. Martin JA, Roorda A. Direct and noninvasive assessment of parafoveal capillary leukocyte velocity. Ophthalmology. 2005;112: 2219-2224.
18. Liang J, Williams DR, Miller DT. Supernormal vision and highresolution retinal imaging through adaptive optics. J Opt Soc Am A Opt Image Sci Vis. 1997;14:2884-2892.
19. Ooto S, Hangai M, Sakamoto A, et al. High-resolution imaging of resolved central serous chorioretinopathy using adaptive optics scanning laser ophthalmoscopy. Ophthalmology. 2010;117:1800-1809, e1801-e1802.
20. Roorda A, Romero-Borja F, Donnelly W III, et al. Adaptive optics scanning laser ophthalmoscopy. Opt Express. 2002;10:405-412.
21. Talcott KE, Ratnam K, Sundquist SM, et al. Longitudinal study of cone photoreceptors during retinal degeneration and in response to ciliary neurotrophic factor treatment. Invest Ophthalmol Vis Sci. 2011;52:2219-2226.
22. Ooto S, Hangai M, Takayama K, et al. High-resolution imaging of the photoreceptor layer in epiretinal membrane using adaptive optics scanning laser ophthalmoscopy. Ophthalmology. 2011;118: 873-881.
23. Martin JA, Roorda A. Pulsatility of parafoveal capillary leukocytes. Exp Eye Res. 2009;88:356-360.
24. Meinke M, Muller G, Helfmann J, Friebel M. Optical properties of platelets and blood plasma and their influence on the optical behavior of whole blood in the visible to near infrared wavelength range. J Biomed Opt. 2007;12:014024.
25. Hirose F, Nozato K, Saito K, Numajiri Y. A compact adaptive optics scanning laser ophthalmoscope with high-efficiency wavefront correction using dual liquid crystal on silicon-spatial light modulator. Proc of SPIE. 2011;5:7885.
26. Lasers ANSftSUo. American National Standard for the Safe Use of Lasers. ANZI Z136.1-2007. New York: American National Standards Institute; 2007.
27. Arganda-Carreras I, Sorzano C, Marabini R, et al. Consistent and Elastic Registration of Histological Sections Using Vector-Spline Regularization. Berlin; Springer; 2006.
28. Li KY, Roorda A. Automated identification of cone photoreceptors in adaptive optics retinal images. J Opt Soc Am A Opt Image Sci Vis. 2007;24:1358-1363.
29. Bennett AG, Rudnicka AR, Edgar DF. Improvements on Littmann's method of determining the size of retinal features by fundus photography. Graefes Arch Clin Exp Ophthalmol. 1994;232:361-367.
30. Baraas RC, Carroll J, Gunther KL, et al. Adaptive optics retinal imaging reveals S-cone dystrophy in tritan color-vision deficiency. J Opt Soc Am A Opt Image Sci Vis. 2007;24:1438-1447.
31. Morgan JI, Dubra A, Wolfe R, Merigan WH, Williams DR. In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic. Invest Ophthalmol Vis Sci. 2009;50: 1350-1359.
32. Sato Y, Chen J, Yamamoto S, et al. Measuring microcirculation using spatiotemporal image analysis. Lecture Notes Comp Sci. 1995;905:302-308.
33. Tam J, Roorda A. Enhanced detection of cell paths in spatiotemporal plots for noninvasive microscopy of the human retina. International Symposium on Biomedical Imaging ISBI 2010. Proceedings of the 2010 IEEE International Conference on Biomedical Imaging: from Nano to Macro. Rotterdam, The Netherlands, April 14-17, 2010;584-587.
34. Tam J, Tiruveedhula P, Roorda A. Characterization of single-file flow through human retinal parafoveal capillaries using an adaptive optics scanning laser ophthalmoscope. Biomed Opt Express. 2011;2:781-793.
35. Tam J, Roorda A. Speed quantification and tracking of moving objects in adaptive optics scanning laser ophthalmoscopy. J Biomed Opt. 2011;16:036002.
36. Mostany R, Chowdhury TG, Johnston DG, et al. Local hemodynamics dictate long-term dendritic plasticity in peri-infarct cortex. J Neurosci. 2010;30:14116-14126.
37. Schmid-Schonbein GW, Usami S, Skalak R, Chien S. The interaction of leukocytes and erythrocytes in capillary and postcapillary vessels. Microvasc Res. 1980;19:45-70.
38. Tam J, Martin JA, Roorda A. Noninvasive visualization and analysis of parafoveal capillaries in humans. Invest Ophthalmol Vis Sci. 2010;51:1691-1698.
39. Schmid-Schonbein GW, Shih YY, Chien S. Morphometry of human leukocytes. Blood. 1980;56:866-875.
40. Yang Y, Kim S, Kim J. Fluorescent dots in fluorescein angiography and fluorescein leukocyte angiography using a scanning laser ophthalmoscope in humans. Ophthalmology. 1997;104:1670-1676.
41. Arend O, Harris A, Sponsel WE, et al. Macular capillary particle velocities: a blue field and scanning laser comparison. Graefes Arch Clin Exp Ophthalmol. 1995;233:244-249.
42. Koutsiaris AG, Tachmitzi SV, Papavasileiou P, et al. Blood velocity pulse quantification in the human conjunctival pre-capillary arterioles. Microvasc Res. 2010;80:202-208.
43. Lee JJ, Tyml K, Menkis AH, Novick RJ, McKenzie FN. Evaluation of pulsatile and nonpulsatile flow in capillaries of goat skeletal muscle using intravital microscopy. Microvasc Res. 1994;48: 316-327.