Characterization of single-file flow through human retinal parafoveal capillaries using an adaptive optics scanning laser ophthalmoscope

Biomedical Optics Express

Volumn 2, Issue 4, 2011, Pages 781-793

  Tam, Johnny ^a   Tiruveedhula, Pavan ^b   Roorda, Austin ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OPHTHALMOLOGY;

FLOWTHROUGH; GAP FLOWS; OFFLINE; SCANNING LASER OPHTHALMOSCOPE; SCANNING LASER OPHTHALMOSCOPY;

CAPILLARITY;

EID: 79960634610     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.2.000781     Document Type: Article

References (46)

1. B. W. Zweifach, Functional Behavior of the Microcirculation (Charles C Thomas, Springfield, Illinois, 1961).
2. J. C. Hogg, and C. M. Doerschuk, "Leukocyte traffic in the lung," Annu. Rev. Physiol. 57(1), 97-114 (1995).
3. G. W. Schmid-Schönbein, R. Skalak, S. Usami, and S. Chien, "Cell distribution in capillary networks," Microvasc. Res. 19(1), 18-44 (1980).
4. B. W. Zweifach, "Quantitative studies of microcirculatory structure and function. I. Analysis of pressure distribution in the terminal vascular bed in cat mesentery," Circ. Res. 34(6), 843-857 (1974).
5. J. A. Martin, and A. Roorda, "Pulsatility of parafoveal capillary leukocytes," Exp. Eye Res. 88(3), 356-360 (2009).
6. B. W. Zweifach, "Quantitative studies of microcirculatory structure and function. II. Direct measurement of capillary pressure in splanchnic mesenteric vessels," Circ. Res. 34(6), 858-866 (1974).
7. A. S. Popel, and P. C. Johnson, "Microcirculation and Hemorheology," Annu. Rev. Fluid Mech. 37(1), 43-69 (2005).
8. H. H. Lipowsky, "Microvascular rheology and hemodynamics," Microcirculation 12(1), 5-15 (2005).
9. G. W. Schmid-Schönbein, Y. Y. Shih, and S. Chien, "Morphometry of human leukocytes," Blood 56(5), 866-875 (1980).
10. J. Ben-nun, "Comparative flow velocity of erythrocytes and leukocytes in feline retinal capillaries," Invest. Ophthalmol. Vis. Sci. 37(9), 1854-1859 (1996).
11. W. M. Kuebler, G. E. H. Kuhnle, J. Groh, and A. E. Goetz, "Leukocyte kinetics in pulmonary microcirculation: intravital fluorescence microscopic study," J. Appl. Physiol. 76(1), 65-71 (1994).
12. E. R. Damiano, and T. M. Stace, "Flow and deformation of the capillary glycocalyx in the wake of a leukocyte," Phys. Fluids 17(3), 031509 (2005).
13. J. M. Fitz-Gerald, "Plasma motions in narrow capillary flow," J. Fluid Mech. 51(03), 463-476 (1972).
14. A. R. Pries, T. W. Secomb, P. Gaehtgens, and J. F. Gross, "Blood flow in microvascular networks. Experiments and simulation," Circ. Res. 67(4), 826-834 (1990).
15. G. W. Schmid-Schönbein, S. Usami, R. Skalak, and S. Chien, "The interaction of leukocytes and erythrocytes in capillary and postcapillary vessels," Microvasc. Res. 19(1), 45-70 (1980).
16. D. W. Sutton, and G. W. Schmid-Schönbein, "Elevation of organ resistance due to leukocyte perfusion," Am. J. Physiol. 262(6 Pt 2), H1646-H1650 (1992).
17. J. A. Martin, and A. Roorda, "Direct and non-invasive assessment of parafoveal capillary leukocyte velocity," Ophthalmology 112(12), 2219-2224 (2005).
18. Y. Zhang, S. Poonja, and A. Roorda, "MEMS-based adaptive optics scanning laser ophthalmoscopy," Opt. Lett. 31(9), 1268-1270 (2006).
19. A. Roorda, F. Romero-Borja, W. Donnelly III, H. Queener, T. J. Hebert, and M. C. W. Campbell, "Adaptive optics scanning laser ophthalmoscopy," Opt. Express 10(9), 405-412 (2002).
20. J. Tam, J. A. Martin, and A. Roorda, "Noninvasive visualization and analysis of parafoveal capillaries in humans," Invest. Ophthalmol. Vis. Sci. 51(3), 1691-1698 (2010).
21. L. Laatikainen, and J. Larinkari, "Capillary-free area of the fovea with advancing age," Invest. Ophthalmol. Vis. Sci. 16(12), 1154-1157 (1977).
22. D. M. Snodderly, R. S. Weinhaus, and J. C. Choi, "Neural-vascular relationships in central retina of macaque monkeys (Macaca fascicularis)," J. Neurosci. 12(4), 1169-1193 (1992).
23. E. Evans, and Y. C. Fung, "Improved measurements of the erythrocyte geometry," Microvasc. Res. 4(4), 335-347 (1972).
24. G. A. Lutty, J. Cao, and D. S. McLeod, "Relationship of polymorphonuclear leukocytes to capillary dropout in the human diabetic choroid," Am. J. Pathol. 151(3), 707-714 (1997).
25. P. K. Yu, C. Balaratnasingam, S. J. Cringle, I. L. McAllister, J. Provis, and D. Y. Yu, "Microstructure and network organisation of the microvasculature in the human macula," Invest. Ophthalmol. Vis. Sci. 51(12) 6735-6743 (2010).
26. I. C. Michaelson, Retinal Circulation in Man and Animals (Charles C Thomas, Springfield, Illinois, USA, 1954).
27. D. Kleinfeld, P. P. Mitra, F. Helmchen, and W. Denk, "Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex," Proc. Natl. Acad. Sci. U.S.A. 95(26), 15741-15746 (1998).
28. B. W. Zweifach, D. B. Metz, and E. R. Clark, "Selective distribution of blood through the terminal vascular bed of mesenteric structures and skeletal muscle," Angiology 6(4), 282-290 (1955).
29. A. G. Hudetz, "Blood flow in the cerebral capillary network: a review emphasizing observations with intravital microscopy," Microcirculation 4(2), 233-252 (1997).
30. E. Friedman, T. R. Smith, and T. Kuwabara, "Retinal Microcirculation in vivo," Invest. Ophthalmol. 3, 217-226 (1964).
31. R. Flower, E. Peiretti, M. Magnani, L. Rossi, S. Serafini, Z. Gryczynski, and I. Gryczynski, "Observation of erythrocyte dynamics in the retinal capillaries and choriocapillaris using ICG-loaded erythrocyte ghost cells," Invest. Ophthalmol. Vis. Sci. 49(12), 5510-5516 (2008).
32. P. S. Jensen, and M. R. Glucksberg, "Regional variation in capillary hemodynamics in the cat retina," Invest. Ophthalmol. Vis. Sci. 39(2), 407-415 (1998).
33. H. Nishiwaki, Y. Ogura, H. Kimura, J. Kiryu, K. Miyamoto, and N. Matsuda, "Visualization and quantitative analysis of leukocyte dynamics in retinal microcirculation of rats," Invest. Ophthalmol. Vis. Sci. 37(7), 1341-1347 (1996).
34. D. A. Nelson, S. Krupsky, A. Pollack, E. Aloni, M. Belkin, I. Vanzetta, M. Rosner, and A. Grinvald, "Special report: Noninvasive multi-parameter functional optical imaging of the eye," Ophthalmic Surg. Lasers Imaging 36(1), 57-66 (2005).
35. M. Paques, B. Boval, S. Richard, R. Tadayoni, P. Massin, O. Mundler, A. Gaudric, and E. Vicaut, "Evaluation of fluorescein-labeled autologous leukocytes for examination of retinal circulation in humans," Curr. Eye Res. 21(1), 560-565 (2000).
36. H. M. Becker, M. Chen, J. B. Hay, and M. I. Cybulsky, "Tracking of leukocyte recruitment into tissues of mice by in situ labeling of blood cells with the fluorescent dye CFDA SE," J. Immunol. Methods 286(1-2), 69-78 (2004).
37. G. W. Schmid-Schönbein, K. L. Sung, H. Tözeren, R. Skalak, and S. Chien, "Passive mechanical properties of human leukocytes," Biophys. J. 36(1), 243-256 (1981).
38. American National Standard for the Safe Use of Lasers, ANSI Z136.1-2007 (American National Standard Institute, New York, 2007).
39. K. Y. Li, P. Tiruveedhula, and A. Roorda, "Intersubject variability of foveal cone photoreceptor density in relation to eye length," Invest. Ophthalmol. Vis. Sci. 51(12), 6858-6867 (2010).
40. D. W. Arathorn, Q. Yang, C. R. Vogel, Y. Zhang, P. Tiruveedhula, and A. Roorda, "Retinally stabilized cone-targeted stimulus delivery," Opt. Express 15(21), 13731-13744 (2007).
41. C. R. Vogel, D. W. Arathorn, A. Roorda, and A. Parker, "Retinal motion estimation in adaptive optics scanning laser ophthalmoscopy," Opt. Express 14(2), 487-497 (2006).
42. J. Tam, and A. Roorda, "Enhanced detection of cell paths in spatiotemporal plots for noninvasive microscopy of the human retina," in 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro (IEEE, 2010), pp. 584-587.
43. J. Tam, and A. Roorda, "Speed quantification and tracking of moving objects in adaptive optics scanning laser ophthalmoscopy," J. Biomed. Opt. (to be published).
44. C. E. Riva, and B. Petrig, "Blue field entoptic phenomenon and blood velocity in the retinal capillaries," J. Opt. Soc. Am. 70(10), 1234-1238 (1980).
45. M. Meinke, G. Müller, J. Helfmann, and M. Friebel, "Optical properties of platelets and blood plasma and their influence on the optical behavior of whole blood in the visible to near infrared wavelength range," J. Biomed. Opt. 12(1), 014024 (2007).
46. T. Nagaoka, and A. Yoshida, "Noninvasive evaluation of wall shear stress on retinal microcirculation in humans," Invest. Ophthalmol. Vis. Sci. 47(3), 1113-1119 (2006).