In Vivo Evaluation of Retinal Injury after Transient Ischemia in Hypertensive Rats

Hypertension

Volumn 43, Issue 5, 2004, Pages 1098-1102

  Hirose, Fumitaka ^a   Kiryu, Junichi ^a   Miyamoto, Kazuaki ^a   Nishijima, Kazuaki ^a   Miyahara, Shinsuke ^a   Katsuta, Hideto ^a   Tamura, Hiroshi ^a   Honda, Yoshihito ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cell adhesion molecules; Ischemia; Leukocytes; Oxidative stress; Rats, inbred SHR

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL INTERACTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; ESSENTIAL HYPERTENSION; HISTOPATHOLOGY; HYPERTENSION; INFLAMMATION; LEUKOCYTE; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; REPERFUSION; RETINA INJURY; RETINA ISCHEMIA; UPREGULATION;

ANIMALS; CHEMOTAXIS, LEUKOCYTE; ENDOTHELIUM, VASCULAR; EYE PROTEINS; GENE EXPRESSION REGULATION; HYPERTENSION; INTERCELLULAR ADHESION MOLECULE-1; ISCHEMIA; LEUKOCYTES; MALE; MICROCIRCULATION; OXIDATIVE STRESS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; REPERFUSION INJURY; RETINA; RETINAL VESSELS; RNA, MESSENGER; SUPEROXIDE DISMUTASE; TIME FACTORS; VASOCONSTRICTION;

EID: 2342452652     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000123069.02156.8a     Document Type: Article

References (27)

1. Wan Nazaimoon WM, Letchuman R, Noraini N, Ropilah AR, Zainal M, Ismail IS, Wan Mohamad WB, Faridah I, Singaraveloo M, Sheriff IH, Khalid BA. Systolic hypertension and duration of diabetes mellitus are important determinants of retinopathy and microalbuminuria in young diabetics. Diabetes Res Clin Pract. 1999;46:213-221.
2. Macular Photocoagulation Study Group. Risk factors for choroidal neovascularization in the second eye of patients with juxtafoveal or subfoveal choroidal neovascularization secondary to age-related macular degeneration. Arch Ophthalmol. 1997;115:741-747.
3. Klein R, Klein BE, Moss SE. The relation of systemic hypertension to changes in the retinal vasculature: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 1997;95:329-350.
4. The Eye Disease Case-Control Study Group. Risk factors for central retinal vein occlusion. Arch Ophthalmol. 1996;114:545-554.
5. Hirvela H, Laatikainen L. Visual acuity in a population aged 70 years or older; prevalence and causes of visual impairment. Acta Ophthalmol Scand. 1995;73:99-104.
6. Tso MO, Jampol LM. Pathophysiology of hypertensive retinopathy. Ophthalmology. 1982;89:1132-1145.
7. Batist G, Mersereau W, Malashenko BA, Chiu RC. Response to ischemia-reperfusion injury in hypertrophic heart. Role of free-radical metabolic pathways. Circulation. 1989;80:III10-13.
8. Tagami M, Yamagata K, Ikeda K, Fujino H, Nara Y, Nakagawa K, Kubota A, Numano F, Yamori Y. Genetic vulnerability of cortical neurons isolated from stroke-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion. Hypertens Res. 1999;22:23-29.
9. Suzuki H, DeLano FA, Parks DA, Jamshidi N, Granger DN, Ishii H, Suematsu M, Zweifach BW, Schmid-Schonbein GW. Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats. Proc Natl Acad Sci USA. 1998;95:4754-4759.
10. Ferrari R, Ceconi C, Curello S, Cargnoni A, Alfieri O, Pardini A, Marzollo P, Visioli O. Oxygen free radicals and myocardial damage: protective role of thiol-containing agents. Am J Med. 1991;91:95S-105S.
11. Curello S, Ceconi C, de Giuli F, Panzali AF, Milanesi B, Calarco M, Pardini A, Marzollo P, Alfieri O, Messineo F, Ferrari R. Oxidative stress during reperfusion of human hearts: potential sources of oxygen free radicals. Cardiovasc Res. 1995;29:118-125.
12. Szabo ME, Droy-Lefaix MT, Doly M. Direct measurement of free radicals in ischemic/reperfused diabetic rat retina. Clin Neurosci. 1997;4:240-245.
13. Nishijima K, Kiryu J, Tsujikawa A, Honjo M, Nonaka A, Yamashiro K, Kamizuru H, Ieki Y, Tanihara H, Honda Y, Ogura Y. Inhibitory effects of antithrombin III on interactions between blood cells and endothelial cells during retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 2003;44:332-341.
14. Tsujikawa A, Ogura Y, Hiroshiba N, Miyamoto K, Kiryu S, Tojo SJ, Miyasaka M, Honda Y. Retinal ischemia-reperfusion injury attenuated by blocking of adhesion molecules of vascular endothelium. Invest Ophthalmol Vis Sci. 1999;40:1183-1190.
15. Tsujikawa A, Kiryu J, Yamashiro K, Nonaka A, Nishijima K, Honda Y, Ogura Y. Interactions between blood cells and retinal endothelium in endotoxic sepsis. Hypertension. 2000;36:250-258.
16. Tsujikawa A, Ogura Y, Hiroshiba N, Miyamoto K, Kiryu J, Honda Y. In vivo evaluation of leukocyte dynamics in retinal ischemia/reperfusion injury. Invest Ophthalmol Vis Sci. 1998;39:793-800.
17. Lucchesi BR, Werns SW, Fantone JC. The role of the neutrophil and free radicals in ischemic myocardial injury. J Mol Cell Cardiol. 1989;21:1241-1251.
18. Miyahara S, Kiryu J, Tsujikawa A, Katsuta H, Nishijima K, Miyamoto K, Yamashiro K, Nonaka A, Honda Y. Argatroban attenuates leukocyte- and platelet-endothelial cell interactions after transient retinal ischemia. Stroke. 2003;34:2043-2049.
19. Miyahara S, Kiryu J, Yamashiro K, Miyamoto K, Hirose F, Tamura H, Katsuta H, Nishijima K, Tsujikawa A, Honda Y. Simvastatin Inhibits leukocyte accumulation and vascular permeability in the retinas of rats with streptozotocin-Induced diabetes. Am J Pathol. In Press.
20. Liu Y, Liu T, McCarron RM, Spatz M, Feuerstein G, Hallenbeck JM, Siren AL. Evidence for activation of endothelium and monocytes in hypertensive rats. Am J Physiol. 1996;270:H2125-2131.
21. Wiemer G, Itter G, Malinski T, Linz W. Decreased nitric oxide availability in normotensive and hypertensive rats with failing hearts after myocardial infarction. Hypertension. 2001;38:1367-1371.
22. Werns SW, Shea MJ, Lucchesi BR. Free radicals in ischemic myocardial injury. J Free Radic Biol Med. 1985;1:103-110.
23. Grisham MB, Hernandez LA, Granger DN. Xanthine oxidase and neutrophil infiltration in intestinal ischemia. Am J Physiol. 1986;251: G567-G574.
24. Schmid-Schonbein GW, Seiffge D, DeLano FA, Shen K, Zweifach BW. Leukocyte counts and activation in spontaneously hypertensive and normotensive rats. Hypertension. 1991;17:323-330.
25. Suzuki M, Inauen W, Kvietys PR, Grisham MB, Meininger C, Schelling ME, Granger HJ, Granger DN. Superoxide mediates reperfusion-induced leukocyte-endothelial cell interactions. Am J Physiol. 1989;257:H1740-H1745.
26. Szabo ME, Droy-Lefaix MT, Doly M. Modification of reperfusion-induced ionic imbalance by free radical scavengers in spontaneously hypertensive rat retina. Free Radic Biol Med. 1992;13:609-620.
27. Nilsson SF. Nitric oxide as a mediator of parasympathetic vasodilation in ocular and extraocular tissues in the rabbit. Invest Ophthalmol Vis Sci. 1996;37:2110-2119.