Monocytes from tuberculosis patients that exhibit cleaved caspase 9 and denaturalized cytochrome c are more susceptible to death mediated by Toll-like receptor 2

Immunology

Volumn 135, Issue 4, 2012, Pages 299-311

  Chávez Galán, Leslie ^a   Sada Ovalle, Isabel ^a   Baez Saldaña, Renata ^a   Chávez, Raúl ^b   Lascurain, Ricardo ^b  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Apoptosis; Monocytes; Mycobacterium tuberculosis; Toll like receptor 2

Indexed keywords

CASPASE 8; CASPASE 9; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE P38; MYCOBACTERIUM ANTIGEN; NEUTRALIZING ANTIBODY; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CELL CULTURE; CELL DEATH; CELL DENSITY; CELL DIVISION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MONOCYTE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; TUBERCULOSIS; TUBERCULOUS PLEURISY;

ADULT; ANTIGENS, BACTERIAL; APOPTOSIS; CASPASE 9; CYTOCHROMES C; FEMALE; HUMANS; MALE; MIDDLE AGED; MONOCYTES; MYCOBACTERIUM TUBERCULOSIS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TUBERCULOSIS; YOUNG ADULT;

EID: 84857721234     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2011.03543.x     Document Type: Article

References (37)

1. World Health Organization. Global tuberculosis control - surveillance, planning, financing. WHO report 2008, WHO/HTM/TB/2008.393.
2. Lee J, Hartman M, Kornfeld H. Macrophage apoptosis in tuberculosis. Yonsei Med J 2009; 50:1-11.
3. Brightbill HD, Libraty DH, Krutzik SR et al. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 1999; 285:732-6.
4. Means TK, Wang S, Lien E, Yoshimura A, Golenbock DT, Fenton MJ. Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis. J Immunol 1999; 163:3920-7.
5. Underhill DM, Ozinsky A, Smith KD, Aderem A. Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages. Proc Natl Acad Sci USA 1999; 96:14459-63.
6. Thoma-Uszynski S, Stenger S, Takeuchi O et al. Induction of direct antimicrobial activity through mammalian toll-like receptors. Science 2001; 291:1544-7.
7. Jung SB, Yang CS, Lee JS et al. The mycobacterial 38-kilodalton glycolipoprotein antigen activates the mitogen-activated protein kinase pathway and release of proinflammatory cytokines through Toll-like receptors 2 and 4 in human monocytes. Infect Immun 2006; 74:2686-96.
8. Yang CS, Shin DM, Lee HM et al. ASK1-p38 MAPK-p47phox activation is essential for inflammatory responses during tuberculosis via TLR2-ROS signaling. Cell Microbiol 2008; 10:741-54.
9. Aliprantis AO, Yang RB, Mark MR et al. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 1999; 285:736-9.
10. López M, Sly LM, Luu Y, Young D, Cooper H, Reiner NE. The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2. J Immunol 2003; 170:2409-16.
11. Ciaramella A, Cavone A, Santucci MB et al. Induction of apoptosis and release of interleukin-1 beta by cell wall-associated 19-kDa lipoprotein during the course of mycobacterial infection. J Infect Dis 2004; 190:1167-76.
12. Sanchez A, Espinosa P, Esparza MA, Colon M, Bernal G, Mancilla R. Mycobacterium tuberculosis 38-kDa lipoprotein is apoptogenic for human monocyte-derived macrophages. Scand J Immunol 2009; 69:20-8.
13. American Thoracic Society and the Centers for Disease Control and Prevention, Diagnosis Standards and Classification of tuberculosis in adults and children. Am J Respir Crit Care Med 2000; 161:1376-95.
14. Boyum A. Isolation of lymphocytes, granulocytes and macrophages. Scand J Immunol 1976; 5:9-15.
15. Lecoeur H, Février M, Garcia S, Rivière Y, Gougeon ML. A novel flow cytometric assay for quantitation and multiparametric characterization of cell-mediated cytotoxicity. J Immunol Methods 2001; 253:177-87.
16. Gallagher S, Winston SE, Fuller SA, Hurrell JG. Chapter 8 Unit 8.10. Immunoblotting and immunodetection. In: Coligan JE, Bierer B, Margulies DH, Shevach EM, Strober W, Coico R, eds. Current Protocols in Immunology. Somerset, NJ: Wiley Online Library, 2001:8.10.1-10.21.
17. Means TK, Jones BW, Schromm AB et al. Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses. J Immunol 2001; 166:4074-82.
18. Aliprantis AO, Yang RB, Weiss DS, Godowski P, Zychlinsky A. The apoptotic signaling pathway activated by Toll-like receptor-2. EMBO J 2000; 19:3325-36.
19. Yuk JM, Shin DM, Yang CS, Kim KH, Rho J, Park JK, Jo EK. Role of apoptosis-regulating signal kinase 1 in innate immune responses by Mycobacterium bovis bacillus Calmette-Guérin. Immunol Cell Biol 2009; 87:100-7.
20. Sánchez MD, García Y, Montes C, París SC, Rojas M, Barrera LF, Arias MA, García LF. Functional and phenotypic changes in monocytes from patients with tuberculosis are reversed with treatment. Microbes Infect 2006; 8:2492-500.
21. Janols H, Bredberg A, Thuvesson I, Janciauskiene S, Grip O, Wullt M. Lymphocyte and monocyte flow cytometry immunophenotyping as a diagnostic tool in uncharacteristic inflammatory disorders. BMC Infect Dis 2010; 10:205.
22. Prabha C, Rajashree P, Sulochana DD. TLR2 and TLR4 expression on the immune cells of tuberculous pleural fluid. Immunol Lett 2008; 117:26-34.
23. Rocha-Ramírez LM, Estrada-García I, López-Marín LM et al. Mycobacterium tuberculosis lipids regulate cytokines, TLR-2/4 and MHC class II expression in human macrophages. Tuberculosis (Edinb) 2008; 88:212-20.
24. Drennan MB, Nicolle D, Quesniaux VJ et al. Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection. Am J Pathol 2004; 164:49-57.
25. Ben-Ali M, Barbouche MR, Bousnina S, Chabbou A, Dellagi K. Toll-like receptor 2 Arg677Trp polymorphism is associated with susceptibility to tuberculosis in Tunisian patients. Clin Diagn Lab Immunol 2004; 11:625-6.
26. Ogus AC, Yoldas B, Ozdemir T et al. The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease. Eur Respir J 2004; 23:219-23.
27. Hölscher C, Reiling N, Schaible UE et al. Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9. Eur J Immunol 2008; 38:680-94.
28. McBride A, Bhatt K, Salgame P. Development of a secondary immune response to Mycobacterium tuberculosis is independent of Toll-like receptor 2. Infect Immun 2011; 79:1118-23.
29. Pecora ND, Gehring AJ, Canaday DH, Boom WH, Harding CV. Mycobacterium tuberculosis LprA is a lipoprotein agonist of TLR2 that regulates innate immunity and APC function. J Immunol 2006; 177:422-9.
30. Dao DN, Kremer L, Guérardel Y, Molano A, Jacobs WR Jr, Porcelli SA, Briken V. Mycobacterium tuberculosis lipomannan induces apoptosis and interleukin-12 production in macrophages. Infect Immun 2004; 72:2067-74.
31. Abbas AK, Lichtman AH, Pillai S. Cellular and Molecular Immunology, 6th edn. Philadelphia, PA: Saunders Elsevier, 2007.
32. Slee EA, Harte MT, Kluck RM et al. Ordering the cytochrome C-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J Cell Biol 1999; 144:281-92.
33. Sánchez D, Rojas M, Hernández I, Radzioch D, García LF, Barrera LF. Role of TLR2- and TLR4-mediated signaling in Mycobacterium tuberculosis-induced macrophage death. Cell Immunol 2010; 260:128-36.
34. Rojas M, Olivier M, Gros P, Barrera LF, García LF. TNF-α and IL-10 modulate the induction of apoptosis by virulent Mycobacterium tuberculosis in murine macrophages. J Immunol 1999; 162:6122-31.
35. Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, Wilson CB, Schroeder L, Aderem A. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci USA 2000; 97:13766-71.
36. Jin MS, Kim SE, Heo JY, Lee ME, Kim HM, Paik SG, Lee H, Lee JO. Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell 2007; 130:1071-82.
37. Kang JK, Nan X, Jin MS et al. Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer. Immunity 2009; 31:873-84.