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Volumn 97, Issue 3, 2012, Pages 328-330

Activation of the NOTCH1 pathway in chronic lymphocytic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; NOTCH1 RECEPTOR;

EID: 84857709007     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.061721     Document Type: Editorial
Times cited : (27)

References (21)
  • 1
    • 80053621341 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia--genomics lead the way
    • Mertens D, Bullinger L, Stilgenbauer S. Chronic lymphocytic leukemia--genomics lead the way. Haematologica. 2011;96(10):1402-5.
    • (2011) Haematologica. , vol.96 , Issue.10 , pp. 1402-1405
    • Mertens, D.1    Bullinger, L.2    Stilgenbauer, S.3
  • 2
    • 84857733831 scopus 로고    scopus 로고
    • When splicing turns bad
    • Cools J. When splicing turns bad. Haematologica. 2012;97(1):1.
    • (2012) Haematologica. , vol.97 , Issue.1 , pp. 1
    • Cools, J.1
  • 4
    • 79960353160 scopus 로고    scopus 로고
    • Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation
    • Fabbri G, Rasi S, Rossi D, Trifonov V, Khiabanian H, Ma J, et al. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation. J Exp Med. 2011;208(7):1389-401.
    • (2011) J Exp Med. , vol.208 , Issue.7 , pp. 1389-1401
    • Fabbri, G.1    Rasi, S.2    Rossi, D.3    Trifonov, V.4    Khiabanian, H.5    Ma, J.6
  • 5
    • 79960036578 scopus 로고    scopus 로고
    • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
    • Puente XS, Pinyol M, Quesada V, Conde L, Ordóñez GR, Villamor N, et al. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature. 2011;475(7354):101-5.
    • (2011) Nature. , vol.475 , Issue.7354 , pp. 101-105
    • Puente, X.S.1    Pinyol, M.2    Quesada, V.3    Conde, L.4    Ordóñez, G.R.5    Villamor, N.6
  • 6
    • 84855854025 scopus 로고    scopus 로고
    • Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia
    • Rossi D, Rasi S, Fabbri G, Spina V, Fangazio M, Forconi F, et al. Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia. Blood. 2012;119(2):521-9.
    • (2012) Blood. , vol.119 , Issue.2 , pp. 521-529
    • Rossi, D.1    Rasi, S.2    Fabbri, G.3    Spina, V.4    Fangazio, M.5    Forconi, F.6
  • 7
    • 84857739865 scopus 로고    scopus 로고
    • NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL
    • Del Giudice I, Rossi D, Chiaretti S, Marinelli M, Tavolaro S, Gabrielli S, et al. NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL. Haematologica 2012;97(3):437-41.
    • (2012) Haematologica , vol.97 , Issue.3 , pp. 437-441
    • del Giudice, I.1    Rossi, D.2    Chiaretti, S.3    Marinelli, M.4    Tavolaro, S.5    Gabrielli, S.6
  • 10
    • 84860705573 scopus 로고    scopus 로고
    • Characteristics of chronic lymphocytic leukemia with somatically acquired mutations in NOTCH1 exon 34
    • doi: 10.1038/leu.2011.361. [Epub ahead of print]
    • Shedden K, Li Y, Ouillette P, Malek SN. Characteristics of chronic lymphocytic leukemia with somatically acquired mutations in NOTCH1 exon 34. Leukemia. 2011. doi: 10.1038/leu.2011.361. [Epub ahead of print].
    • (2011) Leukemia
    • Shedden, K.1    Li, Y.2    Ouillette, P.3    Malek, S.N.4
  • 11
    • 33644782668 scopus 로고    scopus 로고
    • Recent insights into the role of Notch signaling in tumorigenesis
    • Leong KG, Karsan A. Recent insights into the role of Notch signaling in tumorigenesis. Blood. 2006;107(6):2223-33.
    • (2006) Blood. , vol.107 , Issue.6 , pp. 2223-2233
    • Leong, K.G.1    Karsan, A.2
  • 12
    • 83455234787 scopus 로고    scopus 로고
    • Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium and of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative. Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
    • Malcovati L, Papaemmanuil E, Bowen DT, Boultwood J, Della Porta MG, Pascutto C, et al. Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium and of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative. Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms. Blood. 2011;118(24):6239-46.
    • (2011) Blood. , vol.118 , Issue.24 , pp. 6239-6246
    • Malcovati, L.1    Papaemmanuil, E.2    Bowen, D.T.3    Boultwood, J.4    della Porta, M.G.5    Pascutto, C.6
  • 13
    • 59649083306 scopus 로고    scopus 로고
    • Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells
    • Rosati E, Sabatini R, Rampino G, Tabilio A, Di Ianni M, Fettucciari K, et al. Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells. Blood. 2009;113(4):856-65.
    • (2009) Blood. , vol.113 , Issue.4 , pp. 856-865
    • Rosati, E.1    Sabatini, R.2    Rampino, G.3    Tabilio, A.4    di Ianni, M.5    Fettucciari, K.6
  • 15
    • 79961059215 scopus 로고    scopus 로고
    • Array-based genomic screening at diagnosis and during followup in chronic lymphocytic leukemia
    • Gunnarsson R, Mansouri L, Isaksson A, Göransson H, Cahill N, Jansson M, et al. Array-based genomic screening at diagnosis and during followup in chronic lymphocytic leukemia. Haematologica. 2011;96(8):1161-9.
    • (2011) Haematologica. , vol.96 , Issue.8 , pp. 1161-1169
    • Gunnarsson, R.1    Mansouri, L.2    Isaksson, A.3    Göransson, H.4    Cahill, N.5    Jansson, M.6
  • 16
    • 42149109062 scopus 로고    scopus 로고
    • In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of Tcell acute lymphoblastic leukemia
    • De Keersmaecker K, Lahortiga I, Mentens N, Folens C, Van Neste L, Bekaert S, et al. In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of Tcell acute lymphoblastic leukemia. Haematologica. 2008;93(4):533-42.
    • (2008) Haematologica. , vol.93 , Issue.4 , pp. 533-542
    • de Keersmaecker, K.1    Lahortiga, I.2    Mentens, N.3    Folens, C.4    van Neste, L.5    Bekaert, S.6
  • 17
    • 67349250920 scopus 로고    scopus 로고
    • Downregulation of Notch signaling by gamma-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines
    • Liu S, Breit S, Danckwardt S, Muckenthaler MU, Kulozik AE. Downregulation of Notch signaling by gamma-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines. Ann Hematol. 2009;88(7):613-21.
    • (2009) Ann Hematol. , vol.88 , Issue.7 , pp. 613-621
    • Liu, S.1    Breit, S.2    Danckwardt, S.3    Muckenthaler, M.U.4    Kulozik, A.E.5
  • 18
    • 34548592412 scopus 로고    scopus 로고
    • A phase I clinical trial of the notch inhibitor MK-0752 in patients with Tcell acute lymphoblastic leukemia/lymphoma (T-ALL) and other leukemia
    • Deangelo D, Stone R, Silverman L, Stock W, Attar E, Fearen I, et al. A phase I clinical trial of the notch inhibitor MK-0752 in patients with Tcell acute lymphoblastic leukemia/lymphoma (T-ALL) and other leukemia. ASCO annual Meeting. J Clin Oncol 2006; 24:6585.
    • (2006) ASCO annual Meeting. J Clin Oncol , vol.24 , pp. 6585
    • Deangelo, D.1    Stone, R.2    Silverman, L.3    Stock, W.4    Attar, E.5    Fearen, I.6
  • 19
    • 80054045386 scopus 로고    scopus 로고
    • Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL
    • Sulis ML, Saftig P, Ferrando AA. Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL. Leukemia. 2011;25(10):1564-9.
    • (2011) Leukemia. , vol.25 , Issue.10 , pp. 1564-1569
    • Sulis, M.L.1    Saftig, P.2    Ferrando, A.A.3
  • 20
    • 77949395629 scopus 로고    scopus 로고
    • Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors
    • Aste-Amézaga M, Zhang N, Lineberger JE, Arnold BA, Toner TJ, Gu M, et al. Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. PLoS One. 2010;5(2):e9094.
    • (2010) PLoS One. , vol.5 , Issue.2
    • Aste-Amézaga, M.1    Zhang, N.2    Lineberger, J.E.3    Arnold, B.A.4    Toner, T.J.5    Gu, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.