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Volumn 190, Issue 1, 2012, Pages 11-15

TRP channel antagonists as potential antitussives

Author keywords

Cough; Sensory nerves; TRPA1; TRPV1

Indexed keywords

ANTITUSSIVE AGENT; G PROTEIN COUPLED RECEPTOR; NON PRESCRIPTION DRUG; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST;

EID: 84857655238     PISSN: 03412040     EISSN: 14321750     Source Type: Journal    
DOI: 10.1007/s00408-011-9322-3     Document Type: Article
Times cited : (18)

References (62)
  • 2
    • 33748528804 scopus 로고    scopus 로고
    • Cough in the community: A cross sectional survey and the relationship to gastrointestinal symptoms
    • DOI 10.1136/thx.2006.060087
    • A Ford D Forman P Moayyedi A Morice 2006 Cough in the community: a cross sectional survey and the relationship to gastrointestinal symptoms Thorax 61 975 979 16809412 10.1136/thx.2006.060087 1:STN:280:DC%2BD28njs1entQ%3D%3D (Pubitemid 44787168)
    • (2006) Thorax , vol.61 , Issue.11 , pp. 975-979
    • Ford, A.C.1    Forman, D.2    Moayyedi, P.3    Morice, A.H.4
  • 4
    • 84857654537 scopus 로고    scopus 로고
    • World Health Organisation Accessed22Sept2011
    • World Health Organisation (2011) Fact sheet no. 307: asthma. http://www.who.int/mediacentre/factsheets/fs307/en/index.html. Accessed 22 Sept 2011
    • (2011) Fact Sheet No. 307: Asthma
  • 6
    • 27144543197 scopus 로고    scopus 로고
    • The prevalence of symptoms and consultations in pre-school children in the Avon Longitudinal Study of Parents and Children (ALSPAC): A prospective cohort study
    • DOI 10.1093/fampra/cmi035
    • AD Hay J Heron A Ness 2005 The prevalence of symptoms and consultations in pre-school children in the Avon Longitudinal Study of Parents and Children (ALSPAC): a prospective cohort study Fam Pract 22 4 367 374 15897210 10.1093/fampra/cmi035 (Pubitemid 41487369)
    • (2005) Family Practice , vol.22 , Issue.4 , pp. 367-374
    • Hay, A.D.1    Heron, J.2    Ness, A.3
  • 7
    • 84860218035 scopus 로고    scopus 로고
    • Medical problems presenting to paediatric emergency departments: 10 years on
    • doi: 10.1136/emj.2010.106229
    • Sands R, Shanmugavadivel D, Stephenson T, Wood D (2011) Medical problems presenting to paediatric emergency departments: 10 years on. Emerg Med J. doi: 10.1136/emj.2010.106229
    • (2011) Emerg Med J.
    • Sands, R.1    Shanmugavadivel, D.2    Stephenson, T.3    Wood, D.4
  • 9
    • 17344389008 scopus 로고    scopus 로고
    • Toxicity of over-the-counter cough and cold medications
    • 11533370 10.1542/peds.108.3.e52 1:STN:280:DC%2BD3MvptFSqtw%3D%3D
    • V Gunn S Taha E Liebelt J Serwint 2001 Toxicity of over-the-counter cough and cold medications Pediatrics 108 E52 11533370 10.1542/peds.108.3.e52 1:STN:280:DC%2BD3MvptFSqtw%3D%3D
    • (2001) Pediatrics , vol.108 , pp. 52
    • Gunn, V.1    Taha, S.2    Liebelt, E.3    Serwint, J.4
  • 10
    • 33846412220 scopus 로고    scopus 로고
    • Infant deaths associated with cough and cold medications-two states, 2005
    • Centers for Disease Control
    • Centers for Disease Control 2007 Infant deaths associated with cough and cold medications-two states, 2005 Morb Mortal Wkly Rep 56 1 4
    • (2007) Morb Mortal Wkly Rep , vol.56 , pp. 1-4
  • 11
    • 65549119749 scopus 로고    scopus 로고
    • Adverse reactions to over-the-counter cough and cold products among children: The cases managed out of hospitals
    • 19646077 10.1111/j.1365-2710.2008.01010.x 1:STN:280: DC%2BD1MrivVGhtg%3D%3D
    • Z Vassilev A Chu B Ruk E Adams S Marcus 2009 Adverse reactions to over-the-counter cough and cold products among children: the cases managed out of hospitals J Clin Pharm Ther 34 313 318 19646077 10.1111/j.1365-2710.2008. 01010.x 1:STN:280:DC%2BD1MrivVGhtg%3D%3D
    • (2009) J Clin Pharm Ther , vol.34 , pp. 313-318
    • Vassilev, Z.1    Chu, A.2    Ruk, B.3    Adams, E.4    Marcus, S.5
  • 13
    • 0032823711 scopus 로고    scopus 로고
    • Pharmacological regulation of the cough reflex - From experimental models to antitussive effects in man
    • DOI 10.1006/pupt.1999.0207
    • J Karlsson R Fuller 1999 Pharmacological regulation of the cough reflex-from experimental models to antitussive effects in man Pulm Pharmacol Ther 12 215 228 10500001 10.1006/pupt.1999.0207 1:CAS:528:DyaK1MXmt1ajtLs%3D (Pubitemid 29462254)
    • (1999) Pulmonary Pharmacology and Therapeutics , vol.12 , Issue.4 , pp. 215-228
    • Karlsson, J.-A.1    Fuller, R.W.2
  • 14
    • 2442433528 scopus 로고    scopus 로고
    • Cough·7: Current and future drugs for the treatment of chronic cough
    • DOI 10.1136/thx.2003.013490
    • MG Belvisi P Geppetti 2004 Cough 7: current and future drugs for the treatment of chronic cough Thorax 59 438 440 15115877 10.1136/thx.2003.013490 1:STN:280:DC%2BD2c3jvVOltQ%3D%3D (Pubitemid 38624752)
    • (2004) Thorax , vol.59 , Issue.5 , pp. 438-440
    • Belvisi, M.G.1    Geppetti, P.2
  • 15
  • 16
    • 33745872519 scopus 로고    scopus 로고
    • Vagal afferent nerves regulating the cough reflex
    • DOI 10.1016/j.resp.2006.03.001, PII S1569904806001030
    • B Canning N Mori S Mazzone 2006 Vagal afferent nerves regulating the cough reflex Respir Physiol Neurobiol 152 223 242 16740418 10.1016/j.resp.2006. 03.001 (Pubitemid 44037512)
    • (2006) Respiratory Physiology and Neurobiology , vol.152 , Issue.3 , pp. 223-242
    • Canning, B.J.1    Mori, N.2    Mazzone, S.B.3
  • 17
    • 70449519959 scopus 로고    scopus 로고
    • Modulation of sensory nerve function and the cough reflex: Understanding disease pathogenesis
    • 19818366 10.1016/j.pharmthera.2009.09.006 1:CAS:528:DC%2BD1MXhsVKgsL7O
    • J Nasra MG Belvisi 2009 Modulation of sensory nerve function and the cough reflex: understanding disease pathogenesis Pharmacol Ther 124 3 354 375 19818366 10.1016/j.pharmthera.2009.09.006 1:CAS:528:DC%2BD1MXhsVKgsL7O
    • (2009) Pharmacol Ther , vol.124 , Issue.3 , pp. 354-375
    • Nasra, J.1    Belvisi, M.G.2
  • 19
    • 70350543343 scopus 로고    scopus 로고
    • Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents
    • 19845671 10.1111/j.1476-5381.2009.00438.x 1:CAS:528:DC%2BD1MXhsFSkurjJ
    • E Andre R Gatti M Trevisani D Preti P Baraldi R Patacchini P Geppetti 2009 Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents Br J Pharmacol 158 1621 1628 19845671 10.1111/j.1476-5381. 2009.00438.x 1:CAS:528:DC%2BD1MXhsFSkurjJ
    • (2009) Br J Pharmacol , vol.158 , pp. 1621-1628
    • Andre, E.1    Gatti, R.2    Trevisani, M.3    Preti, D.4    Baraldi, P.5    Patacchini, R.6    Geppetti, P.7
  • 20
    • 0028805448 scopus 로고
    • Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs
    • 8567546 1:CAS:528:DyaK2MXptlSitrw%3D
    • U Lalloo A Fox MG Belvisi F Chung 1995 Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs J Appl Physiol 79 1082 1087 8567546 1:CAS:528:DyaK2MXptlSitrw%3D
    • (1995) J Appl Physiol , vol.79 , pp. 1082-1087
    • Lalloo, U.1    Fox, A.2    Belvisi, M.G.3    Chung, F.4
  • 22
    • 0030777012 scopus 로고    scopus 로고
    • The capsaicin receptor: A heat-activated ion channel in the pain pathway
    • DOI 10.1038/39807
    • M Caterina M Schumacher M Tominaga T Rosen J Levine D Julius 1997 The capsaicin receptor: a heat-activated ion channel in the pain pathway Nature 389 816 824 9349813 10.1038/39807 1:CAS:528:DyaK2sXmvFSksbs%3D (Pubitemid 27462969)
    • (1997) Nature , vol.389 , Issue.6653 , pp. 816-824
    • Caterina, M.J.1    Schumacher, M.A.2    Tominaga, M.3    Rosen, T.A.4    Levine, J.D.5    Julius, D.6
  • 23
    • 0033614984 scopus 로고    scopus 로고
    • Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
    • DOI 10.1038/22761
    • PM Zygmunt J Petersson DA Andersson H Chuang M Søgard V Di Marzo D Julius ED Högestätt 1999 Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide Nature 400 452 457 10440374 10.1038/22761 1:CAS:528:DyaK1MXltVGmsrk%3D (Pubitemid 29361798)
    • (1999) Nature , vol.400 , Issue.6743 , pp. 452-457
    • Zygmunt, P.M.1    Petersson, J.2    Andersson, D.A.3    Chuang, H.-H.4    Sorgard, M.5    Di Marzo, V.6    Julius, D.7    Hogestatt, E.D.8
  • 26
    • 1642430679 scopus 로고    scopus 로고
    • Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
    • DOI 10.1038/nature02282
    • SE Jordt DM Bautista H Chuang DD McKemy PM Zygmunt ED Högestätt ID Meng D Julius 2004 Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1 Nature 427 260 265 14712238 10.1038/nature02282 1:CAS:528:DC%2BD2cXjtFKitg%3D%3D (Pubitemid 38112043)
    • (2004) Nature , vol.427 , Issue.6971 , pp. 260-265
    • Jordt, S.-E.1    Bautista, D.M.2    Chuang, H.-H.3    McKemy, D.D.4    Zygmunt, P.M.5    Hogestatt, E.D.6    Meng, I.D.7    Julius, D.8
  • 28
    • 33646045075 scopus 로고    scopus 로고
    • TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
    • 16564016 10.1016/j.cell.2006.02.023 1:CAS:528:DC%2BD28Xjt1Khs70%3D
    • D Bautista S Jordt T Nikai P Tsuruda A Read J Poblete E Yamoah A Basbaum D Julius 2006 TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents Cell 124 1269 1282 16564016 10.1016/j.cell.2006.02.023 1:CAS:528:DC%2BD28Xjt1Khs70%3D
    • (2006) Cell , vol.124 , pp. 1269-1282
    • Bautista, D.1    Jordt, S.2    Nikai, T.3    Tsuruda, P.4    Read, A.5    Poblete, J.6    Yamoah, E.7    Basbaum, A.8    Julius, D.9
  • 29
    • 1842475312 scopus 로고    scopus 로고
    • Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
    • DOI 10.1016/S0896-6273(04)00150-3, PII S0896627304001503
    • M Bandell GM Story SW Hwang, et al. 2004 Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin Neuron 41 849 857 15046718 10.1016/S0896-6273(04)00150-3 1:CAS:528:DC%2BD2cXjtValtL8%3D (Pubitemid 38429729)
    • (2004) Neuron , vol.41 , Issue.6 , pp. 849-857
    • Bandell, M.1    Story, G.M.2    Hwang, S.W.3    Viswanath, V.4    Eid, S.R.5    Petrus, M.J.6    Earley, T.J.7    Patapoutian, A.8
  • 30
    • 20144371097 scopus 로고    scopus 로고
    • The pungency of garlic: Activation of TRPA1 and TRPV1 in response to allicin
    • DOI 10.1016/j.cub.2005.04.018, PII S096098220500391X
    • LJ Macpherson BH Geierstanger V Viswanath, et al. 2005 The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin Curr Biol 15 929 934 15916949 10.1016/j.cub.2005.04.018 1:CAS:528:DC%2BD2MXks1Gjt7s%3D (Pubitemid 40772062)
    • (2005) Current Biology , vol.15 , Issue.10 , pp. 929-934
    • Macpherson, L.J.1    Geierstanger, B.H.2    Viswanath, V.3    Bandell, M.4    Eid, S.R.5    Hwang, S.6    Patapoutian, A.7
  • 32
    • 33846692923 scopus 로고    scopus 로고
    • Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
    • DOI 10.1038/nature05544, PII NATURE05544
    • LJ Macpherson AE Dubin MJ Evans, et al. 2007 Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines Nature 445 541 545 17237762 10.1038/nature05544 1:CAS:528:DC%2BD2sXhtFWhur0%3D (Pubitemid 46197634)
    • (2007) Nature , vol.445 , Issue.7127 , pp. 541-545
    • Macpherson, L.J.1    Dubin, A.E.2    Evans, M.J.3    Marr, F.4    Schultz, P.G.5    Cravatt, B.F.6    Patapoutian, A.7
  • 36
    • 49549124987 scopus 로고    scopus 로고
    • Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor
    • 18501939 10.1016/j.taap.2008.04.005
    • B Brône PJ Peeters R Marrannes, et al. 2008 Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor Toxicol Appl Pharmacol 231 150 156 18501939 10.1016/j.taap.2008.04.005
    • (2008) Toxicol Appl Pharmacol , vol.231 , pp. 150-156
    • Brône, B.1    Peeters, P.J.2    Marrannes, R.3
  • 37
    • 40449121206 scopus 로고    scopus 로고
    • Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress
    • DOI 10.1523/JNEUROSCI.5369-07.2008
    • DA Andersson C Gentry S Moss, et al. 2008 Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress J Neurosci 28 2485 2494 18322093 10.1523/JNEUROSCI.5369-07.2008 1:CAS:528:DC%2BD1cXjt1Ghu7Y%3D (Pubitemid 351348185)
    • (2008) Journal of Neuroscience , vol.28 , Issue.10 , pp. 2485-2494
    • Andersson, D.A.1    Gentry, C.2    Moss, S.3    Bevan, S.4
  • 38
    • 9644289587 scopus 로고    scopus 로고
    • Airway inflammation and remodelling changes in patients with chronic cough: Do they tell us about the cause of cough?
    • DOI 10.1016/j.pupt.2004.09.004, PII S1094553904000690
    • A Niimi KF Chung 2004 Airway inflammation and remodelling changes in patients with chronic cough: Do they tell us about the cause of cough? Pulm Pharmacol Ther 17 441 446 15564089 10.1016/j.pupt.2004.09.004 1:CAS:528:DC%2BD2cXhtVantr7O (Pubitemid 39572488)
    • (2004) Pulmonary Pharmacology and Therapeutics , vol.17 , Issue.6 SPEC.ISS. , pp. 441-446
    • Niimi, A.1    Chung, K.F.2
  • 39
    • 0028158384 scopus 로고
    • The relation of sleep complaints to respiratory symptoms in a general population
    • ME Klink R Dodge SF Quan 1994 The relation of sleep complaints to respiratory symptoms in a general population Chest 105 151 154 8275723 10.1378/chest.105.1.151 1:STN:280:DyaK2c7gtFyqug%3D%3D (Pubitemid 24029093)
    • (1994) Chest , vol.105 , Issue.1 , pp. 151-154
    • Klink, M.E.1    Dodge, R.2    Quan, S.F.3
  • 40
    • 34250812002 scopus 로고    scopus 로고
    • Chronic persistent cough in the community: A questionnaire survey
    • 17381836 10.1186/1745-9974-3-5
    • CF Everett JA Kastelik RH Thompson AH Morice 2007 Chronic persistent cough in the community: a questionnaire survey Cough 3 5 17381836 10.1186/1745-9974-3-5
    • (2007) Cough , vol.3 , pp. 5
    • Everett, C.F.1    Kastelik, J.A.2    Thompson, R.H.3    Morice, A.H.4
  • 41
    • 57649221998 scopus 로고    scopus 로고
    • Urinary incontinence in 9-16 year olds with cystic fibrosis compared to other respiratory conditions and a normal group
    • 18930699 10.1016/j.jcf.2008.09.002 1:STN:280:DC%2BD1M%2FhvVKrtg%3D%3D
    • WJ Browne CJ Wood M Desai PH Weller 2009 Urinary incontinence in 9-16 year olds with cystic fibrosis compared to other respiratory conditions and a normal group J Cyst Fibros 8 50 57 18930699 10.1016/j.jcf.2008.09.002 1:STN:280:DC%2BD1M%2FhvVKrtg%3D%3D
    • (2009) J Cyst Fibros , vol.8 , pp. 50-57
    • Browne, W.J.1    Wood, C.J.2    Desai, M.3    Weller, P.H.4
  • 43
    • 70449528788 scopus 로고    scopus 로고
    • 3 reeptor: Implications for future disease therapy
    • 19729667 10.1164/rccm.200903-0388OC 1:CAS:528:DC%2BD1MXhsFahur%2FN
    • 3 reeptor: implications for future disease therapy Am J Respir Crit Care Med 180 923 928 19729667 10.1164/rccm.200903-0388OC 1:CAS:528:DC%2BD1MXhsFahur%2FN
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 923-928
    • Maher, S.A.1    Birrell, M.A.2    Belvisi, M.G.3
  • 44
    • 0029995843 scopus 로고    scopus 로고
    • Bradykinin-evoked sensitization of airway sensory nerves: A mechanism for ACE-inhibitor cough
    • DOI 10.1038/nm0796-814
    • A Fox U Lalloo M Belvisi M Bernareggi KF Chung P Barnes 1996 Bradykinin evoked sensitisation of airway sensory nerves: a mechanism for ACE-inhibitor cough Nat Med 2 814 817 8673930 10.1038/nm0796-814 1:CAS:528:DyaK28XjvF2isrc%3D (Pubitemid 26225100)
    • (1996) Nature Medicine , vol.2 , Issue.7 , pp. 814-817
    • Fox, A.J.1    Lalloo, U.G.2    Belvisi, M.G.3    Bernareggi, M.4    Chung, K.F.5    Barnes, P.J.6
  • 48
    • 0036786014 scopus 로고    scopus 로고
    • PGE(2) sensitizes cultured pulmonary vagal sensory neurons to chemical and electrical stimuli
    • 12235043 1:CAS:528:DC%2BD38XotFOqtLY%3D
    • K Kwong LY Lee 2002 PGE(2) sensitizes cultured pulmonary vagal sensory neurons to chemical and electrical stimuli J Appl Physiol 93 4 1419 1428 12235043 1:CAS:528:DC%2BD38XotFOqtLY%3D
    • (2002) J Appl Physiol , vol.93 , Issue.4 , pp. 1419-1428
    • Kwong, K.1    Lee, L.Y.2
  • 49
    • 1542329731 scopus 로고    scopus 로고
    • Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/-mice
    • DOI 10.1113/jphysiol.2003.054890
    • M Kollarik BJ Undem 2004 Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice J Physiol 555 Pt 1 115 123 14634201 1:CAS:528:DC%2BD2cXhvFOrtrk%3D (Pubitemid 38313065)
    • (2004) Journal of Physiology , vol.555 , Issue.1 , pp. 115-123
    • Kollarik, M.1    Undem, B.J.2
  • 50
    • 0035568314 scopus 로고    scopus 로고
    • The TRP channel and phospholipase C-mediated signaling
    • DOI 10.1023/A:1015191702536
    • B Minke 2001 The TRP channel and phospholipase C-mediated signaling Cell Mol Neurobiol 21 629 643 12043838 10.1023/A:1015191702536 1:CAS:528: DC%2BD38XkslSktL8%3D (Pubitemid 34538860)
    • (2001) Cellular and Molecular Neurobiology , vol.21 , Issue.6 , pp. 629-643
    • Minke, B.1
  • 51
    • 44949182742 scopus 로고    scopus 로고
    • Phospholipase C and protein kinase A mediate bradykinin sensitisation of TRPA1: A molecular mechanism of inflammatory pain
    • 18356188 10.1093/brain/awn060
    • S Wang Y Dai T Fukuoka H Yamanaka K Kobayashi K Obata X Cui M Tominaga K Noguchi 2008 Phospholipase C and protein kinase A mediate bradykinin sensitisation of TRPA1: a molecular mechanism of inflammatory pain Brain 131 1241 1251 18356188 10.1093/brain/awn060
    • (2008) Brain , vol.131 , pp. 1241-1251
    • Wang, S.1    Dai, Y.2    Fukuoka, T.3    Yamanaka, H.4    Kobayashi, K.5    Obata, K.6    Cui, X.7    Tominaga, M.8    Noguchi, K.9
  • 52
    • 0035927651 scopus 로고    scopus 로고
    • 2-mediated inhibition
    • DOI 10.1038/35082088
    • H Chuang ED Prescott H Kong S Shields S-E Jordt AI Basbaum MV Chao D Julius 2001 Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4, 5)P2-mediated inhibition Nature 411 957 962 11418861 10.1038/35082088 1:CAS:528:DC%2BD3MXkvVWgs7Y%3D (Pubitemid 32601493)
    • (2001) Nature , vol.411 , Issue.6840 , pp. 957-962
    • Chuang, H.-H.1    Prescott, E.D.2    Kong, H.3    Shields, S.4    Jordt, S.-E.5    Basbaum, A.I.6    Chao, M.V.7    Julius, D.8
  • 53
    • 55649089662 scopus 로고    scopus 로고
    • Direct activation of Transient Receptor Potential Vanilloid 1 (TRPV1) by diacylglycerol (DAG)
    • 18826653 10.1186/1744-8069-4-42
    • DH Woo SJ Jung MH Zhu CK Park YH Kim SB Oh CJ Lee 2008 Direct activation of Transient Receptor Potential Vanilloid 1 (TRPV1) by diacylglycerol (DAG) Mol Pain 4 42 18826653 10.1186/1744-8069-4-42
    • (2008) Mol Pain , vol.4 , pp. 42
    • Woo, D.H.1    Jung, S.J.2    Zhu, M.H.3    Park, C.K.4    Kim, Y.H.5    Oh, S.B.6    Lee, C.J.7
  • 54
    • 0035425705 scopus 로고    scopus 로고
    • Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide
    • DOI 10.1111/j.1469-7793.2001.00813.x
    • V Vellani S Mapplebeck A Moriondo JB Davis PA McNaughton 2001 Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide J Physiol 534 813 825 11483711 10.1111/j.1469-7793.2001.00813.x 1:CAS:528:DC%2BD3MXlvF2nsrc%3D (Pubitemid 32700878)
    • (2001) Journal of Physiology , vol.534 , Issue.3 , pp. 813-825
    • Vellani, V.1    Mapplebeck, S.2    Moriondo, A.3    Davis, J.B.4    McNaughton, P.A.5
  • 55
    • 57749111494 scopus 로고    scopus 로고
    • Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control
    • 10.1152/physiol.00026.2008 1:CAS:528:DC%2BD1MXpvFKmtA%3D%3D
    • BF Bessac SE Jordt 2008 Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control Physiology (Bethesda) 23 360 370 10.1152/physiol.00026.2008 1:CAS:528:DC%2BD1MXpvFKmtA%3D%3D
    • (2008) Physiology (Bethesda) , vol.23 , pp. 360-370
    • Bessac, B.F.1    Jordt, S.E.2
  • 56
    • 58149107126 scopus 로고    scopus 로고
    • Clinical development of TRPV1 antagonists: Targeting a pivotal point in the pain pathway
    • 19063991 10.1016/j.drudis.2008.11.005 1:CAS:528:DC%2BD1MXktVShsA%3D%3D
    • MJ Gunthorpe BA Chizh 2009 Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway Drug Discov Today 14 56 67 19063991 10.1016/j.drudis.2008.11.005 1:CAS:528:DC%2BD1MXktVShsA%3D%3D
    • (2009) Drug Discov Today , vol.14 , pp. 56-67
    • Gunthorpe, M.J.1    Chizh, B.A.2
  • 57
    • 4544227074 scopus 로고    scopus 로고
    • Antitussive activity of iodo-resiniferatoxin in guinea pigs
    • DOI 10.1136/thx.2003.012930
    • M Trevisani A Milan R Gatti A Zanasi S Harrison G Fontana A Morice P Geppetti 2004 Antitussive activity of iodo-resiniferatoxin in guinea pigs Thorax 59 769 772 15333853 10.1136/thx.2003.012930 1:STN:280:DC%2BD2cvivFSntQ%3D%3D (Pubitemid 39215373)
    • (2004) Thorax , vol.59 , Issue.9 , pp. 769-772
    • Trevisani, M.1    Milan, A.2    Gatti, R.3    Zanasi, A.4    Harrison, S.5    Fontana, G.6    Morice, A.H.7    Geppetti, P.8
  • 62
    • 45849089128 scopus 로고    scopus 로고
    • 2+ reveals different functional channel states
    • 18515013 10.1016/j.neuroscience.2008.04.048 1:CAS:528: DC%2BD1cXotlKqsrs%3D
    • 2+ reveals different functional channel states Neuroscience 154 1467 1476 18515013 10.1016/j.neuroscience.2008.04.048 1:CAS:528:DC%2BD1cXotlKqsrs%3D
    • (2008) Neuroscience , vol.154 , pp. 1467-1476
    • Cavanaugh, E.1    Simkin, D.2    Kim, D.3


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