A thermoprotective role of the sodium channel β 1 subunit is lost with the β 1(C121W) mutation

Epilepsia

Volumn 53, Issue 3, 2012, Pages 494-505

  Egri, Csilla ^a   Vilin, Yuriy Y ^a   Ruben, Peter C ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Febrile seizures; GEFS+; Patch clamp; Temperature

Indexed keywords

SODIUM CHANNEL BETA1 SUBUNIT; SODIUM CHANNEL NAV1.2; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHO CELL; CONTROLLED STUDY; EPILEPSY; FEBRILE CONVULSION; GENE MUTATION; NERVE CELL EXCITABILITY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECORDING; TEMPERATURE; VOLTAGE CLAMP; WHOLE CELL; WILD TYPE;

ANIMALS; BODY TEMPERATURE; BRAIN CHEMISTRY; CHO CELLS; CRICETINAE; CRICETULUS; CYTOPROTECTION; DISEASE RESISTANCE; EPILEPSY; GENETIC PREDISPOSITION TO DISEASE; HOT TEMPERATURE; MEMBRANE POTENTIALS; MUTATION; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; PROTEIN SUBUNITS; RATS; SEIZURES, FEBRILE; SODIUM CHANNELS;

EID: 84857644989     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2011.03389.x     Document Type: Article

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