New insight into the antidepressants action: Modulation of kynurenine pathway by increasing the kynurenic acid/3-hydroxykynurenine ratio

Journal of Neural Transmission

Volumn 119, Issue 2, 2012, Pages 235-243

  Kocki, Tomasz ^a   Wnuk, Sebastian ^a   Kloc, Renata ^a   Kocki, Janusz ^a   Owe Larsson, Björn ^b   Urbanska, Ewa M ^a,c  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

Author keywords

3 Hydroxykynurenine; Antidepressants; Depression; Glia; Kynurenic acid

Indexed keywords

3 HYDROXYKYNURENINE; AMITRIPTYLINE; CITALOPRAM; FLUOXETINE; IMIPRAMINE; KYNURENIC ACID; KYNURENINE; KYNURENINE 3 MONOOXYGENASE;

ANIMAL CELL; ANTIDEPRESSANT ACTIVITY; ARTICLE; GENE; GENE EXPRESSION; GLIA CELL; INCUBATION TIME; KAT1 GENE; KAT2 GENE; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANIMALS, NEWBORN; ANTIDEPRESSIVE AGENTS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; KYNURENIC ACID; KYNURENINE; NEURAL PATHWAYS; RATS; RATS, WISTAR; STEREOISOMERISM;

EID: 84857632844     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-011-0668-8     Document Type: Article

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