-
1
-
-
57749177096
-
Endothelial dysfunction and diabetes: Roles of hyperglycemia, impaired insulin signaling and obesity
-
Bakker W, Eringa EC, Sipkema P, van Hinsbergh VW. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res 2009;335:165-189.
-
(2009)
Cell Tissue Res
, vol.335
, pp. 165-189
-
-
Bakker, W.1
Eringa, E.C.2
Sipkema, P.3
Van Hinsbergh, V.W.4
-
2
-
-
33646178955
-
Reciprocal relationships between insulin resistance and endothelial dysfunction: Molecular and pathophysiological mechanisms
-
Kim JA, Montagnani M, Koh KK, Quon MJ. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 2006;113:1888-1904.
-
(2006)
Circulation
, vol.113
, pp. 1888-1904
-
-
Kim, J.A.1
Montagnani, M.2
Koh, K.K.3
Quon, M.J.4
-
3
-
-
50449085395
-
An integrated view of insulin resistance and endothelial dysfunction
-
ix-x
-
Muniyappa R, Iantorno M, Quon MJ. An integrated view of insulin resistance and endothelial dysfunction. Endocrinol Metab Clin North Am 2008;37:685-711, ix-x.
-
(2008)
Endocrinol Metab Clin North Am
, vol.37
, pp. 685-711
-
-
Muniyappa, R.1
Iantorno, M.2
Quon, M.J.3
-
4
-
-
1542545604
-
Endothelial dysfunction in obesity and insulin resistance: A road to diabetes and heart disease
-
Caballero AE. Endothelial dysfunction in obesity and insulin resistance: a road to diabetes and heart disease. Obes Res 2003;11:1278-1289.
-
(2003)
Obes Res
, vol.11
, pp. 1278-1289
-
-
Caballero, A.E.1
-
6
-
-
77951190323
-
Cell and molecular mechanisms of insulin-induced angiogenesis
-
Liu Y, Petreaca M, Martins-Green M. Cell and molecular mechanisms of insulin-induced angiogenesis. J Cell Mol Med 2009;13:4492-4504.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 4492-4504
-
-
Liu, Y.1
Petreaca, M.2
Martins-Green, M.3
-
7
-
-
14944381279
-
Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications
-
Zdychova J, Komers R. Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications. Physiol Res 2005;54:1-16.
-
(2005)
Physiol Res
, vol.54
, pp. 1-16
-
-
Zdychova, J.1
Komers, R.2
-
8
-
-
0036298262
-
Rapamycin partially prevents insulin resistance induced by chronic insulin treatment
-
Berg CE, Lavan BE, Rondinone CM. Rapamycin partially prevents insulin resistance induced by chronic insulin treatment. Biochem Biophys Res Commun 2002;293:1021-1027.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 1021-1027
-
-
Berg, C.E.1
Lavan, B.E.2
Rondinone, C.M.3
-
9
-
-
16844370268
-
Regulation of insulin signalling by hyperinsulinaemia: Role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway
-
Ueno M, Carvalheira JB, Tambascia RC, Bezerra RM, Amaral ME, Carneiro EM et al. Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway. Diabetologia 2005;48:506-518.
-
(2005)
Diabetologia
, vol.48
, pp. 506-518
-
-
Ueno, M.1
Carvalheira, J.B.2
Tambascia, R.C.3
Bezerra, R.M.4
Amaral, M.E.5
Carneiro, E.M.6
-
10
-
-
14244252683
-
Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes
-
Tremblay F, Gagnon A, Veilleux A, Sorisky A, Marette A. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes. Endocrinology 2005;146:1328-1337.
-
(2005)
Endocrinology
, vol.146
, pp. 1328-1337
-
-
Tremblay, F.1
Gagnon, A.2
Veilleux, A.3
Sorisky, A.4
Marette, A.5
-
11
-
-
33646397009
-
Effects of chronic Akt activation on glucose uptake in the heart
-
Matsui T, Nagoshi T, Hong EG, Luptak I, Hartil K, Li L et al. Effects of chronic Akt activation on glucose uptake in the heart. Am J Physiol Endocrinol Metab 2006;290:E789-E797.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Matsui, T.1
Nagoshi, T.2
Hong, E.G.3
Luptak, I.4
Hartil, K.5
Li, L.6
-
12
-
-
67349278461
-
A guide and guard: The many faces of T-cadherin
-
Philippova M, Joshi MB, Kyriakakis E, Pfaff D, Erne P, Resink TJ. A guide and guard: the many faces of T-cadherin. Cell Signal 2009;21:1035-1044.
-
(2009)
Cell Signal
, vol.21
, pp. 1035-1044
-
-
Philippova, M.1
Joshi, M.B.2
Kyriakakis, E.3
Pfaff, D.4
Erne, P.5
Resink, T.J.6
-
13
-
-
0035086062
-
Expression of cell adhesion molecule T-cadherin in the human vasculature
-
Ivanov D, Philippova M, Antropova J, Gubaeva F, Iljinskaya O, Tararak e et al. Expression of cell adhesion molecule T-cadherin in the human vasculature. Histochem Cell Biol 2001;115:231-242.
-
(2001)
Histochem Cell Biol
, vol.115
, pp. 231-242
-
-
Ivanov, D.1
Philippova, M.2
Antropova, J.3
Gubaeva, F.4
Iljinskaya, O.5
Tararak, E.6
-
14
-
-
0036402536
-
Expression of adhesion molecule T-cadherin is increased during neointima formation in experimental restenosis
-
Kudrjashova E, Bashtrikov P, Bochkov V, Parfyonova Y, Tkachuk V, Antropova J et al. Expression of adhesion molecule T-cadherin is increased during neointima formation in experimental restenosis. Histochem Cell Biol 2002;118:281-290.
-
(2002)
Histochem Cell Biol
, vol.118
, pp. 281-290
-
-
Kudrjashova, E.1
Bashtrikov, P.2
Bochkov, V.3
Parfyonova, Y.4
Tkachuk, V.5
Antropova, J.6
-
15
-
-
4444362838
-
T-cadherin upregulation correlates with cell-cycle progression and promotes proliferation of vascular cells
-
Ivanov D, Philippova M, Allenspach R, Erne P, Resink T. T-cadherin upregulation correlates with cell-cycle progression and promotes proliferation of vascular cells. Cardiovasc Res 2004;64:132-143.
-
(2004)
Cardiovasc Res
, vol.64
, pp. 132-143
-
-
Ivanov, D.1
Philippova, M.2
Allenspach, R.3
Erne, P.4
Resink, T.5
-
16
-
-
26444493129
-
T-cadherin protects endothelial cells from oxidative stress-induced apoptosis
-
Joshi MB, Philippova M, Ivanov D, Allenspach R, Erne P, Resink TJ. T-cadherin protects endothelial cells from oxidative stress-induced apoptosis. FASEB J 2005;19:1737-1739.
-
(2005)
FASEB J
, vol.19
, pp. 1737-1739
-
-
Joshi, M.B.1
Philippova, M.2
Ivanov, D.3
Allenspach, R.4
Erne, P.5
Resink, T.J.6
-
17
-
-
77953724324
-
T-cadherin modulates UPR activation and cell survival during endoplasmic reticulum stress in endothelial cells
-
Kyriakakis E, Philippova M, Joshi MB, Pfaff D, Bochkov V, Afonyushkin T et al. T-cadherin modulates UPR activation and cell survival during endoplasmic reticulum stress in endothelial cells. Cell Signal 2010;22:1308-1316.
-
(2010)
Cell Signal
, vol.22
, pp. 1308-1316
-
-
Kyriakakis, E.1
Philippova, M.2
Joshi, M.B.3
Pfaff, D.4
Bochkov, V.5
Afonyushkin, T.6
-
18
-
-
33749064636
-
Atypical GPI-anchored T-cadherin stimulates angiogenesis in vitro and in vivo
-
Philippova M, Banfi A, Ivanov D, Gianni-Barrera R, Allenspach R, Erne P et al. Atypical GPI-anchored T-cadherin stimulates angiogenesis in vitro and in vivo. Arterioscler Thromb Vasc Biol 2006;26:2222-2230.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 2222-2230
-
-
Philippova, M.1
Banfi, A.2
Ivanov, D.3
Gianni-Barrera, R.4
Allenspach, R.5
Erne, P.6
-
19
-
-
79952856179
-
T-cadherin is present on endothelial microparticles and is elevated in plasma in early atherosclerosis
-
Philippova M, Suter Y, Toggweiler S, Schoenenberger AW, Joshi MB, Kyriakakis e et al. T-cadherin is present on endothelial microparticles and is elevated in plasma in early atherosclerosis. Eur Heart J 2011;32:760-771.
-
(2011)
Eur Heart J
, vol.32
, pp. 760-771
-
-
Philippova, M.1
Suter, Y.2
Toggweiler, S.3
Schoenenberger, A.W.4
Joshi, M.B.5
Kyriakakis, E.6
-
21
-
-
78649822277
-
T-cadherin is critical for adiponectin-mediated cardioprotection in mice
-
Denzel MS, Scimia MC, Zumstein PM, Walsh K, Ruiz-Lozano P, Ranscht B. T-cadherin is critical for adiponectin-mediated cardioprotection in mice. J Clin Invest 2010;120:4342-4352.
-
(2010)
J Clin Invest
, vol.120
, pp. 4342-4352
-
-
Denzel, M.S.1
Scimia, M.C.2
Zumstein, P.M.3
Walsh, K.4
Ruiz-Lozano, P.5
Ranscht, B.6
-
22
-
-
40449133794
-
T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model
-
Hebbard LW, Garlatti M, Young LJ, Cardiff RD, Oshima RG, Ranscht B. T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model. Cancer Res 2008;68:1407-1416.
-
(2008)
Cancer Res
, vol.68
, pp. 1407-1416
-
-
Hebbard, L.W.1
Garlatti, M.2
Young, L.J.3
Cardiff, R.D.4
Oshima, R.G.5
Ranscht, B.6
-
23
-
-
3142761477
-
T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin
-
Hug C, Wang J, Ahmad NS, Bogan JS, Tsao TS, Lodish HF. T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc Natl Acad Sci USA 2004;101:10308-10313.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10308-10313
-
-
Hug, C.1
Wang, J.2
Ahmad, N.S.3
Bogan, J.S.4
Tsao, T.S.5
Lodish, H.F.6
-
24
-
-
79251472175
-
Invariant natural killer T cells: Linking inflammation and neovascularization in human atherosclerosis
-
Kyriakakis E, Cavallari M, Andert J, Philippova M, Koella C, Bochkov V et al. Invariant natural killer T cells: linking inflammation and neovascularization in human atherosclerosis. Eur J Immunol 2010;40:3268-3279.
-
(2010)
Eur J Immunol
, vol.40
, pp. 3268-3279
-
-
Kyriakakis, E.1
Cavallari, M.2
Andert, J.3
Philippova, M.4
Koella, C.5
Bochkov, V.6
-
25
-
-
77954875004
-
T-cadherin loss induces an invasive phenotype in human keratinocytes and squamous cell carcinoma (SCC) cells in vitro and is associated with malignant transformation of cutaneous SCC in vivo
-
Pfaff D, Philippova M, Buechner SA, Maslova K, Mathys T, Erne P et al. T-cadherin loss induces an invasive phenotype in human keratinocytes and squamous cell carcinoma (SCC) cells in vitro and is associated with malignant transformation of cutaneous SCC in vivo. Br J Dermatol 2010;163:353-363.
-
(2010)
Br J Dermatol
, vol.163
, pp. 353-363
-
-
Pfaff, D.1
Philippova, M.2
Buechner, S.A.3
Maslova, K.4
Mathys, T.5
Erne, P.6
-
26
-
-
44949176516
-
Identification of proteins associating with glycosylphosphatidylinositol- anchored T-cadherin on the surface of vascular endothelial cells: Role for Grp78/BiP in T-cadherin-dependent cell survival
-
Philippova M, Ivanov D, Joshi MB, Kyriakakis E, Rupp K, Afonyushkin T et al. Identification of proteins associating with glycosylphosphatidylinositol- anchored T-cadherin on the surface of vascular endothelial cells: role for Grp78/BiP in T-cadherin-dependent cell survival. Mol Cell Biol 2008;28:4004-4017.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4004-4017
-
-
Philippova, M.1
Ivanov, D.2
Joshi, M.B.3
Kyriakakis, E.4
Rupp, K.5
Afonyushkin, T.6
-
27
-
-
0347722254
-
Cell adhesion molecule T-cadherin regulates vascular cell adhesion, phenotype and motility
-
Ivanov D, Philippova M, Tkachuk V, Erne P, Resink T. Cell adhesion molecule T-cadherin regulates vascular cell adhesion, phenotype and motility. Exp Cell Res 2004;293:207-218.
-
(2004)
Exp Cell Res
, vol.293
, pp. 207-218
-
-
Ivanov, D.1
Philippova, M.2
Tkachuk, V.3
Erne, P.4
Resink, T.5
-
28
-
-
38449089459
-
Generation of multicellular tumor spheroids by the hangingdrop method
-
Timmins NE, Nielsen LK. Generation of multicellular tumor spheroids by the hangingdrop method. Methods Mol Med 2007;140:141-151.
-
(2007)
Methods Mol Med
, vol.140
, pp. 141-151
-
-
Timmins, N.E.1
Nielsen, L.K.2
-
29
-
-
58149315994
-
A requirement for thioredoxin in redox-sensitive modulation of T-cadherin expression in endothelial cells
-
Joshi MB, Ivanov D, Philippova M, Kyriakakis E, Erne P, Resink TJ. A requirement for thioredoxin in redox-sensitive modulation of T-cadherin expression in endothelial cells. Biochem J 2008;416:271-280.
-
(2008)
Biochem J
, vol.416
, pp. 271-280
-
-
Joshi, M.B.1
Ivanov, D.2
Philippova, M.3
Kyriakakis, E.4
Erne, P.5
Resink, T.J.6
-
30
-
-
77954530704
-
Molecular mechanism of insulin resistance in obesity and type 2 diabetes
-
Choi K, Kim YB. Molecular mechanism of insulin resistance in obesity and type 2 diabetes. Korean J Intern Med 2010;25:119-129.
-
(2010)
Korean J Intern Med
, vol.25
, pp. 119-129
-
-
Choi, K.1
Kim, Y.B.2
-
31
-
-
0036149984
-
Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1
-
Zhande R, Mitchell JJ, Wu J, Sun XJ. Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1. Mol Cell Biol 2002;22:1016-1026.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1016-1026
-
-
Zhande, R.1
Mitchell, J.J.2
Wu, J.3
Sun, X.J.4
-
32
-
-
0034603858
-
Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
-
Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H et al. Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 2000;101:1539-1545.
-
(2000)
Circulation
, vol.101
, pp. 1539-1545
-
-
Zeng, G.1
Nystrom, F.H.2
Ravichandran, L.V.3
Cong, L.N.4
Kirby, M.5
Mostowski, H.6
-
33
-
-
0032511170
-
T-cadherin and signal-transducing molecules co-localize in caveolin-rich membrane domains of vascular smooth muscle cells
-
Philippova MP, Bochkov VN, Stambolsky DV, Tkachuk VA, Resink TJ. T-cadherin and signal-transducing molecules co-localize in caveolin-rich membrane domains of vascular smooth muscle cells. FEBS Lett 1998;429:207-210.
-
(1998)
FEBS Lett
, vol.429
, pp. 207-210
-
-
Philippova, M.P.1
Bochkov, V.N.2
Stambolsky, D.V.3
Tkachuk, V.A.4
Resink, T.J.5
-
34
-
-
35248896777
-
Integrin-linked kinase is an essential mediator for T-cadherin-dependent signaling via Akt and GSK3{beta} in endothelial cells
-
Joshi MB, Ivanov D, Philippova M, Erne P, Resink TJ. Integrin-linked kinase is an essential mediator for T-cadherin-dependent signaling via Akt and GSK3{beta} in endothelial cells. FASEB J 2007;21:3083-3095.
-
(2007)
FASEB J
, vol.21
, pp. 3083-3095
-
-
Joshi, M.B.1
Ivanov, D.2
Philippova, M.3
Erne, P.4
Resink, T.J.5
-
35
-
-
0242268533
-
Insulin signaling in microdomains of the plasma membrane
-
Saltiel AR, Pessin JE. Insulin signaling in microdomains of the plasma membrane. Traffic 2003;4:711-716.
-
(2003)
Traffic
, vol.4
, pp. 711-716
-
-
Saltiel, A.R.1
Pessin, J.E.2
-
36
-
-
0026642585
-
Identification of determinants that confer ligand specificity on the insulin receptor
-
Andersen AS, Kjeldsen T, Wiberg FC, Vissing H, Schaffer L, Rasmussen JS et al. Identification of determinants that confer ligand specificity on the insulin receptor. J Biol Chem 1992;267:13681-13686.
-
(1992)
J Biol Chem
, vol.267
, pp. 13681-13686
-
-
Andersen, A.S.1
Kjeldsen, T.2
Wiberg, F.C.3
Vissing, H.4
Schaffer, L.5
Rasmussen, J.S.6
-
37
-
-
33748744723
-
Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant
-
Slaaby R, Schaffer L, Lautrup-Larsen I, Andersen AS, Shaw AC, Mathiasen IS et al. Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant. J Biol Chem 2006;281:25869-25874.
-
(2006)
J Biol Chem
, vol.281
, pp. 25869-25874
-
-
Slaaby, R.1
Schaffer, L.2
Lautrup-Larsen, I.3
Andersen, A.S.4
Shaw, A.C.5
Mathiasen, I.S.6
-
38
-
-
17644399404
-
Role of insulin-induced reactive oxygen species in the insulin signaling pathway
-
Goldstein BJ, Mahadev K, Wu X, Zhu L, Motoshima H. Role of insulin-induced reactive oxygen species in the insulin signaling pathway. Antioxid Redox Signal 2005;7:1021-1031.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1021-1031
-
-
Goldstein, B.J.1
Mahadev, K.2
Wu, X.3
Zhu, L.4
Motoshima, H.5
-
40
-
-
80052895204
-
A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes
-
Chung CM, Lin TH, Chen JW, Leu HB, Yang HC, Ho HY et al. A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes. Diabetes 2011;60:2417-2423.
-
(2011)
Diabetes
, vol.60
, pp. 2417-2423
-
-
Chung, C.M.1
Lin, T.H.2
Chen, J.W.3
Leu, H.B.4
Yang, H.C.5
Ho, H.Y.6
-
41
-
-
84857533640
-
CDH13 gene coding T-cadherin influences variations in plasma adiponectin levels in Japanese population
-
doi:10.1002/humu.21652
-
Morisaki H, Yamanaka I, Iwai N, Miyamoto Y, Kokubo Y, Okamura T et al. CDH13 gene coding T-cadherin influences variations in plasma adiponectin levels in Japanese population. Hum Mutat 2011; doi:10.1002/humu.21652.
-
(2011)
Hum Mutat
-
-
Morisaki, H.1
Yamanaka, I.2
Iwai, N.3
Miyamoto, Y.4
Kokubo, Y.5
Okamura, T.6
-
42
-
-
80455135068
-
T-cadherin (Cdh13) in association with pancreatic beta-cell granules contributes to second phase insulin secretion
-
Tyrberg B, Miles P, Azizian KT, Denzel MS, Nieves ML, Monosov EZ et al. T-cadherin (Cdh13) in association with pancreatic beta-cell granules contributes to second phase insulin secretion. Islets 2011;3:327-337.
-
(2011)
Islets
, vol.3
, pp. 327-337
-
-
Tyrberg, B.1
Miles, P.2
Azizian, K.T.3
Denzel, M.S.4
Nieves, M.L.5
Monosov, E.Z.6
|