ATP-gated P2X 1 ion channels protect against endotoxemia by dampening neutrophil activation

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 3, 2012, Pages 453-465

  Lecut, C ^a   Faccinetto, C ^a   Delierneux, C ^a   van Oerle, R ^b   Spronk, H M H ^b   Evans, R J ^c   El Benna, J ^d   Bours, V ^a   Oury, C ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

^d CENTRE DE RECHERCHE BIOMÉDICALE BICHAT BEAUJON CRB3   (France)

Author keywords

ATP; Hemostasis; Inflammation; P2X 1; Phagocytes; Sepsis

Indexed keywords

CD11B ANTIGEN; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; PURINERGIC P2X1 RECEPTOR; REACTIVE OXYGEN METABOLITE; THROMBIN ANTITHROMBIN COMPLEX; THROMBOPLASTIN; ADENOSINE TRIPHOSPHATE; CYTOKINE; LIPOPOLYSACCHARIDE, ESCHERICHIA COLI 0111 B4; PEROXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; BLOOD CLOTTING TIME; CONTROLLED STUDY; CYTOKINE PRODUCTION; DESENSITIZATION; ENDOTOXEMIA; HEMOSTASIS; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE AGGREGATION; LIPID PEROXIDATION; LIVER; LUNG; MACROPHAGE; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SEPSIS; SHOCK; THROMBOCYTE AGGREGATION; THROMBOCYTOPENIA; WILD TYPE; ANIMAL; BLOOD CLOTTING; C57BL MOUSE; CELL CULTURE; CHANNEL GATING; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; GENETICS; IMMUNOLOGY; LEUKOCYTE ACTIVATION; METABOLISM; MOUSE MUTANT; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; THROMBOCYTE; THROMBOCYTE ADHESION; TIME;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIGENS, CD11B; BLOOD COAGULATION; BLOOD PLATELETS; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; ENDOTOXEMIA; HUMANS; ION CHANNEL GATING; LIPOPOLYSACCHARIDES; LIVER; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; NEUTROPHIL ACTIVATION; NEUTROPHIL INFILTRATION; NEUTROPHILS; PEROXIDASE; PLATELET ADHESIVENESS; REACTIVE OXYGEN SPECIES; RECEPTORS, PURINERGIC P2X1; SEPSIS; TIME FACTORS;

EID: 84857582404     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04606.x     Document Type: Article

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