Interrogating signaling nodes involved in cellular transformations using kinase activity probes

Chemistry and Biology

Volumn 19, Issue 2, 2012, Pages 210-217

  Stains, Cliff I ^a   Tedford, Nathan C ^b   Walkup, Traci C ^a   Luković, Elvedin ^a   Goguen, Brenda N ^a   Griffith, Linda G ^b   Lauffenburger, Douglas A ^b   Imperiali, Barbara ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOTRANSFERASE; PROTEIN KINASE B;

ARTICLE; CELL DIFFERENTIATION; CELL TRANSFORMATION; CHEMOSENSOR; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; MOLECULAR PROBE; SAMPLING; SENSOR; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; HELA CELLS; HEP G2 CELLS; HT29 CELLS; HUMANS; HYDROXYQUINOLINES; KINETICS; MICE; MUSCLE, SKELETAL; NEOPLASMS; PHOSPHORYLATION; PROTEIN KINASES; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; SULFONAMIDES;

EID: 84857578417     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.11.012     Document Type: Article

References (33)

1. B.B. Aldridge, J. Saez-Rodriguez, J.L. Muhlich, P.K. Sorger, and D.A. Lauffenburger Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling PLoS Comput. Biol. 5 2009 e1000340
2. A.E. Chen, D.D. Ginty, and C.M. Fan Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins Nature 433 2005 317 322
3. R. Chen, O. Kim, J. Yang, K. Sato, K.M. Eisenmann, J. McCarthy, H. Chen, and Y. Qiu Regulation of Akt/PKB activation by tyrosine phosphorylation J. Biol. Chem. 276 2001 31858 31862
4. C. Choudhary, and M. Mann Decoding signalling networks by mass spectrometry-based proteomics Nat. Rev. Mol. Cell Biol. 11 2010 427 439
5. P.Y. Coxon, M.J. Rane, S. Uriarte, D.W. Powell, S. Singh, W. Butt, Q.D. Chen, and K.R. McLeish MAPK-activated protein kinase-2 participates in p38 MAPK-dependent and ERK-dependent functions in human neutrophils Cell. Signal. 15 2003 993 1001 (Pubitemid 37130157)
6. B.J. Feldman, and D. Feldman The development of androgen-independent prostate cancer Nat. Rev. Cancer 1 2001 34 45 (Pubitemid 33741879)
7. Y. Fujio, K. Guo, T. Mano, Y. Mitsuuchi, J.R. Testa, and K. Walsh Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival Mol. Cell. Biol. 19 1999 5073 5082 (Pubitemid 29289545)
8. G.A. Gonzalez, and M.R. Montminy Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133 Cell 59 1989 675 680 (Pubitemid 19282874)
9. A.K. Greenberg, S. Basu, J. Hu, T.A. Yie, K.M. Tchou-Wong, W.N. Rom, and T.C. Lee Selective p38 activation in human non-small cell lung cancer Am. J. Respir. Cell Mol. Biol. 26 2002 558 564 (Pubitemid 34315863)
10. A.M. Gustafson, R. Soldi, C. Anderlind, M.B. Scholand, J. Qian, X. Zhang, K. Cooper, D. Walker, A. McWilliams, and G. Liu Airway PI3K pathway activation is an early and reversible event in lung cancer development Sci. Trans. Med. 2 2010 26ra25
11. N. Kumar, R. Afeyan, S. Sheppard, B. Harms, and D.A. Lauffenburger Quantitative analysis of Akt phosphorylation and activity in response to EGF and insulin treatment Biochem. Biophys. Res. Commun. 354 2007 14 20 (Pubitemid 46123191)
12. M.T. Kunkel, A. Toker, R.Y. Tsien, and A.C. Newton Calcium-dependent regulation of protein kinase D revealed by a genetically encoded kinase activity reporter J. Biol. Chem. 282 2007 6733 6742 (Pubitemid 47100892)
13. C. Lechner, M.A. Zahalka, J.F. Giot, N.P. Møller, and A. Ullrich ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation Proc. Natl. Acad. Sci. USA 93 1996 4355 4359 (Pubitemid 26144291)
14. E. Luković, J.A. González-Vera, and B. Imperiali Recognition-domain focused chemosensors: versatile and efficient reporters of protein kinase activity J. Am. Chem. Soc. 130 2008 12821 12827
15. E. Luković, E. Vogel Taylor, and B. Imperiali Monitoring protein kinases in cellular media with highly selective chimeric reporters Angew. Chem. Int. Ed. Engl. 48 2009 6828 6831
16. A. Mukai, and N. Hashimoto Localized cyclic AMP-dependent protein kinase activity is required for myogenic cell fusion Exp. Cell Res. 314 2008 387 397 (Pubitemid 350216102)
17. E.A. Musgrove, and R.L. Sutherland Biological determinants of endocrine resistance in breast cancer Nat. Rev. Cancer 9 2009 631 643
18. U.B. Nielsen, M.H. Cardone, A.J. Sinskey, G. MacBeath, and P.K. Sorger Profiling receptor tyrosine kinase activation by using Ab microarrays Proc. Natl. Acad. Sci. USA 100 2003 9330 9335 (Pubitemid 37033928)
19. R.A. O'Neill, A. Bhamidipati, X. Bi, D. Deb-Basu, L. Cahill, J. Ferrante, E. Gentalen, M. Glazer, J. Gossett, and K. Hacker Isoelectric focusing technology quantifies protein signaling in 25 cells Proc. Natl. Acad. Sci. USA 103 2006 16153 16158 (Pubitemid 44717502)
20. E. Perdiguero, V. Ruiz-Bonilla, L. Gresh, L. Hui, E. Ballestar, P. Sousa-Victor, B. Baeza-Raja, M. Jardí, A. Bosch-Comas, and M. Esteller Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation EMBO J. 26 2007 1245 1256 (Pubitemid 46398710)
21. A. Pollack, K. Bae, L.Y. Khor, T. Al-Saleem, M.E. Hammond, V. Venkatesan, R.W. Byhardt, S.O. Asbell, W.U. Shipley, and H.M. Sandler The importance of protein kinase A in prostate cancer: relationship to patient outcome in Radiation Therapy Oncology Group trial 92-02 Clin. Cancer Res. 15 2009 5478 5484
22. C. Rommel, B.A. Clarke, S. Zimmermann, L. Nuñez, R. Rossman, K. Reid, K. Moelling, G.D. Yancopoulos, and D.J. Glass Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt Science 286 1999 1738 1741 (Pubitemid 129515881)
23. D.M. Rothman, M.D. Shults, and B. Imperiali Chemical approaches for investigating phosphorylation in signal transduction networks Trends Cell Biol. 15 2005 502 510 (Pubitemid 41253470)
24. M. Sato, Y. Kawai, and Y. Umezawa Genetically encoded fluorescent indicators to visualize protein phosphorylation by extracellular signal-regulated kinase in single living cells Anal. Chem. 79 2007 2570 2575 (Pubitemid 46449042)
25. M.D. Shults, and B. Imperiali Versatile fluorescence probes of protein kinase activity J. Am. Chem. Soc. 125 2003 14248 14249 (Pubitemid 37452343)
26. M.D. Shults, K.A. Janes, D.A. Lauffenburger, and B. Imperiali A multiplexed homogeneous fluorescence-based assay for protein kinase activity in cell lysates Nat. Methods 2 2005 277 283 (Pubitemid 41131009)
27. C.I. Stains, E. Luković, and B. Imperiali A p38α-selective chemosensor for use in unfractionated cell lysates ACS Chem. Biol. 6 2011 101 105
28. M. Tagawa, T. Ueyama, T. Ogata, N. Takehara, N. Nakajima, K. Isodono, S. Asada, T. Takahashi, H. Matsubara, and H. Oh MURC, a muscle-restricted coiled-coil protein, is involved in the regulation of skeletal myogenesis Am. J. Physiol. Cell Physiol. 295 2008 C490 C498
29. K.K. Tomczak, V.D. Marinescu, M.F. Ramoni, D. Sanoudou, F. Montanaro, M. Han, L.M. Kunkel, I.S. Kohane, and A.H. Beggs Expression profiling and identification of novel genes involved in myogenic differentiation FASEB J. 18 2004 403 405
30. H.X. Wang, Q. Xu, F. Xiao, Y. Jiang, and Z.G. Wu Involvement of the p38 mitogen-activated protein kinase alpha, beta, and gamma isoforms in myogenic differentiation Mol. Biol. Cell 19 2008 1519 1528 (Pubitemid 351805105)
31. Q. Wang, S.M. Cahill, M. Blumenstein, and D.S. Lawrence Self-reporting fluorescent substrates of protein tyrosine kinases J. Am. Chem. Soc. 128 2006 1808 1809 (Pubitemid 43277318)
32. Q. Wang, E.I. Zimmerman, A. Toutchkine, T.D. Martin, L.M. Graves, and D.S. Lawrence Multicolor monitoring of dysregulated protein kinases in chronic myelogenous leukemia ACS Chem. Biol. 5 2010 887 895
33. K. Xiao, J. Sun, J. Kim, S. Rajagopal, B. Zhai, J. Villén, W. Haas, J.J. Kovacs, A.K. Shukla, and M.R. Hara Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) Proc. Natl. Acad. Sci. USA 107 2010 15299 15304