In vivo lamellar bone formation in fibre coated MgCHA-PCL-composite scaffolds

Journal of Materials Science: Materials in Medicine

Volumn 23, Issue 1, 2012, Pages 117-128

  Scaglione, Silvia ^a   Guarino, Vincenzo ^a   Sandri, Monica ^b   Tampieri, Anna ^b   Ambrosio, Luigi ^a   Quarto, Rodolfo ^c  

^a CNR   (Italy)

^b INSTITUTE OF SCIENCE AND TECHNOLOGY FOR CERAMICS   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3D SCAFFOLDS; BIO-INSPIRED MATERIALS; BIOLOGICAL RESPONSE; BONE DEFECT; BONE FORMATION; BONE MARROW; BONE REGENERATION; BONE TISSUE; CELL POTENTIAL; CONTACT GUIDANCE; ELECTROSPINNING TECHNIQUES; EXTRACELLULAR MATRICES; HISTOLOGICAL ANALYSIS; IN-VITRO; IN-VIVO; INTERCONNECTED PORES; NATURAL TISSUES; PHASE INVERSION; PHYSICAL FEATURES; POROUS STRUCTURES; REGENERATIVE MEDICINE; STILL MISSING; STRUCTURAL MODIFICATIONS;

BIOMATERIALS; BONE; COATED MATERIALS; LEACHING; TISSUE;

SCAFFOLDS (BIOLOGY);

HYDROXYAPATITE; MAGNESIUM DOPED HYDROXYAPATITE; POLYCAPROLACTONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; BONE TISSUE; CONFERENCE PAPER; ELECTROSPINNING; HEMATOPOIETIC STEM CELL; HISTOLOGY; IN VIVO STUDY; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE DEVELOPMENT; BONE MARROW CELLS; IMMUNOHISTOCHEMISTRY; MICE; TISSUE SCAFFOLDS;

EID: 84857528572     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-011-4489-y     Document Type: Conference Paper

References (73)

1. B Barrilleaux DG Phinney DJ Prockop KC O'Connor 2006 Review: ex vivo engineering of living tissues with adult stem cells Tissue Eng 12 11 3007 3019 10.1089/ten.2006.12.3007 1:CAS:528:DC%2BD28Xht1CgtbrL (Pubitemid 44846407)
2. R Cancedda G Bianchi A Derubeis R Quarto 2003 Cell therapy for bone disease: a review of current status Stem Cells 21 5 610 619 10.1634/stemcells. 21-5-610 1:CAS:528:DC%2BD3sXnvFeis7o%3D (Pubitemid 37444117)
3. D Logeart-Avramoglou F Anagnostou R Bizios H Petite 2005 Engineering bone: challenges and obstacles J Cell Mol Med 9 1 72 84 10.1111/j.1582-4934. 2005.tb00338.x 1:CAS:528:DC%2BD2MXlt1eqtLs%3D
4. RO Oreffo JT Triffitt 1999 Future potentials for using osteogenic stem cells and biomaterials in orthopedics Bone 25 2 Suppl 5S 9S 10.1016/S8756- 3282(99)00124-6 1:STN:280:DyaK1MzosFCnug%3D%3D (Pubitemid 29333170)
5. S Srouji T Kizhner E Livne 2006 3D scaffolds for bone marrow stem cell support in bone repair Regen Med 1 4 519 528 10.2217/17460751.1.4.519 1:CAS:528:DC%2BD28Xosl2gsrw%3D
6. SM Warren RK Nacamuli HM Song MT Longaker 2004 Tissue-engineered bone using mesenchymal stem cells and a biodegradable scaffold J Craniofac Surg 15 1 34 37 10.1097/00001665-200401000-00012
7. L Cheng F Ye R Yang X Lu Y Shi L Li, et al. 2010 Osteoinduction of hydroxyapatite/beta-tricalcium phosphate bioceramics in mice with a fractured fibula Acta Biomater 6 4 1569 1574 10.1016/j.actbio.2009.10.050 1:CAS:528:DC%2BC3cXkvVOqsL0%3D
8. H Fan T Ikoma J Tanaka X Zhang 2007 Surface structural biomimetics and the osteoinduction of calcium phosphate biomaterials J Nanosci Nanotechnol 7 3 808 813 10.1166/jnn.2007.501 1:CAS:528:DC%2BD2sXjvVyhs7o%3D
9. N Kondo A Ogose K Tokunaga H Umezu K Arai N Kudo, et al. 2006 Osteoinduction with highly purified beta-tricalcium phosphate in dog dorsal muscles and the proliferation of osteoclasts before heterotopic bone formation Biomaterials 27 25 4419 4427 10.1016/j.biomaterials.2006.04.016 1:CAS:528:DC%2BD28XkvVajsbY%3D
10. T Nakamura 2007 Biomaterial osteoinduction J Orthop Sci 12 2 111 112 10.1007/s00776-007-1109-2 (Pubitemid 46723687)
11. U Ripamonti 1996 Osteoinduction in porous hydroxyapatite implanted in heterotopic sites of different animal models Biomaterials 17 1 31 35 10.1016/0142-9612(96)80752-6 1:CAS:528:DyaK28XhvFyjtA%3D%3D (Pubitemid 126755189)
12. H Yuan K Kurashina JD de Bruijn Y Li K de Groot X Zhang 1999 A preliminary study on osteoinduction of two kinds of calcium phosphate ceramics Biomaterials 20 19 1799 1806 10.1016/S0142-9612(99)00075-7 1:CAS:528: DyaK1MXmt1yiurw%3D (Pubitemid 29421729)
13. A El-Ghannam 2005 Bone reconstruction: from bioceramics to tissue engineering Expert Rev Med Devices 2 1 87 101 10.1586/17434440.2.1.87 (Pubitemid 40124904)
14. O Gauthier JM Bouler E Aguado P Pilet G Daculsi 1998 Macroporous biphasic calcium phosphate ceramics: influence of macropore diameter and macroporosity percentage on bone ingrowth Biomaterials 19 1-3 133 139 10.1016/S0142-9612(97) 00180-4 1:CAS:528:DyaK1cXjtlyqs7w%3D (Pubitemid 28239476)
15. SJ Hollister RD Maddox JM Taboas 2002 Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints Biomaterials 23 20 4095 4103 10.1016/S0142-9612(02)00148-5 1:CAS:528: DC%2BD38Xlt1Ohtrw%3D (Pubitemid 34765701)
16. JA Hunt 2008 Regenerative medicine: materials in a cellular world Nat Mater 7 8 617 618 10.1038/nmat2242 1:CAS:528:DC%2BD1cXovFWrtbk%3D
17. DW Hutmacher 2000 Scaffolds in tissue engineering bone and cartilage Biomaterials 21 24 2529 2543 10.1016/S0142-9612(00)00121-6 1:CAS:528: DC%2BD3cXmvFyls7k%3D
18. V Karageorgiou D Kaplan 2005 Porosity of 3D biomaterial scaffolds and osteogenesis Biomaterials 26 27 5474 5491 10.1016/j.biomaterials.2005.02.002 1:CAS:528:DC%2BD2MXjs1Wnsrc%3D (Pubitemid 40592136)
19. X Liu PX Ma 2004 Polymeric scaffolds for bone tissue engineering Ann Biomed Eng 32 3 477 486 10.1023/B:ABME.0000017544.36001.8e
20. M Mastrogiacomo S Scaglione R Martinetti L Dolcini F Beltrame R Cancedda, et al. 2006 Role of scaffold internal structure on in vivo bone formation in macroporous calcium phosphate bioceramics Biomaterials 27 17 3230 3237 10.1016/j.biomaterials.2006.01.031 1:CAS:528:DC%2BD28Xit1aisbc%3D (Pubitemid 43348525)
21. SL Ishaug-Riley GM Crane-Kruger MJ Yaszemski AG Mikos 1998 Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers Biomaterials 19 15 1405 1412 10.1016/S0142-9612(98)00021-0 1:CAS:528:DyaK1cXlvFOhsL4%3D (Pubitemid 28425460)
22. TD Roy JL Simon JL Ricci ED Rekow VP Thompson JR Parsons 2003 Performance of degradable composite bone repair products made via three-dimensional fabrication techniques J Biomed Mater Res A 66 2 283 291 10.1002/jbm.a.10582 (Pubitemid 37517228)
23. V Guarino F Causa A Salerno L Ambrosio PA Netti 2008 Design and manufacture of microporous polymeric materials with hierarchal complex structure for biomedical application Mater Sci Technol 24 9 1111 1117 10.1179/174328408X341799 1:CAS:528:DC%2BD1cXhsVSisbfP
24. Guarino V, Guaccio A, Guarnieri D, Netti PA, Ambrosio L. Binary system thermodynamics to control pore architecture of PCL scaffold via temperature-driven phase separation process. J Biomater Appl; 2011.
25. J Lee V Guarino A Gloria L Ambrosio G Tae YH Kim, et al. 2010 Regeneration of Achilles' tendon: the role of dynamic stimulation for enhanced cell proliferation and mechanical properties J Biomater Sci Polym Ed 21 8-9 1173 1190 10.1163/092050609X12471222313524 1:CAS:528:DC%2BC3cXovVWrs7g%3D
26. H Chim DW Hutmacher AM Chou AL Oliveira RL Reis TC Lim, et al. 2006 A comparative analysis of scaffold material modifications for load-bearing applications in bone tissue engineering Int J Oral Maxillofac Surg 35 10 928 934 10.1016/j.ijom.2006.03.024 1:STN:280:DC%2BD28nnslCltQ%3D%3D (Pubitemid 44566018)
27. J Zhao LY Guo XB Yang J Weng 2008 Preparation of bioactive porous HA/PCL composite scaffolds Appl Surf Sci 255 5 2942 2946 10.1016/j.apsusc.2008.08.056 1:CAS:528:DC%2BD1cXhsVChsr3P
28. V Guarino F Causa PA Netti G Ciapetti S Pagani D Martini, et al. 2008 The role of hydroxyapatite as solid signal on performance of PCL porous scaffolds for bone tissue regeneration J Biomed Mater Res B Appl Biomater 86B 2 548 557 10.1002/jbm.b.31055 1:CAS:528:DC%2BD1cXptFCjsrk%3D
29. S Scaglione C Ilengo M Fato R Quarto 2009 Hydroxyapatite-coated polycaprolacton wide mesh as a model of open structure for bone regeneration Tissue Eng Part A 15 1 155 163 10.1089/ten.tea.2007.0410 1:CAS:528: DC%2BD1MXht1emug%3D%3D
30. F Causa PA Netti L Ambrosio 2007 A multi-functional scaffold for tissue regeneration: the need to engineer a tissue analogue Biomaterials 28 34 5093 5099 10.1016/j.biomaterials.2007.07.030 1:CAS:528:DC%2BD2sXhtFalsr3M (Pubitemid 47489795)
31. PX Ma 2008 Biomimetic materials for tissue engineering Adv Drug Deliv Rev 60 2 184 198 10.1016/j.addr.2007.08.041 1:CAS:528:DC%2BD2sXhsVelt7vM (Pubitemid 350245692)
32. Elliott JC. Structure and chemistry of the apatites and other calcium orthophosphates, studies in inorganic chemistry, vol. 18. Amsterdam: Elsevier; 1994.
33. JD Termine ED Eanes 1972 Comparative chemistry of amorphous and apatitic calcium phosphate preparations Calcif Tissue Res 10 3 171 197 10.1007/BF02012548 1:CAS:528:DyaE3sXitlemsw%3D%3D
34. RP Heaney 2006 Role of dietary sodium in osteoporosis J Am Coll Nutr 25 3 Suppl 271S 276S 1:CAS:528:DC%2BD28XmvFGqtLs%3D (Pubitemid 46931006)
35. E Landi G Logroscino L Proietti A Tampieri M Sandri S Sprio 2008 Biomimetic Mg-substituted hydroxyapatite: from synthesis to in vivo behaviour J Mater Sci Mater Med 19 1 239 247 10.1007/s10856-006-0032-y 1:CAS:528: DC%2BD1cXltVyjsw%3D%3D
36. S Dasgupta SS Banerjee A Bandyopadhyay S Bose 2010 Zn- and Mg-doped hydroxyapatite nanoparticles for controlled release of protein Langmuir 26 7 4958 4964 10.1021/la903617e 1:CAS:528:DC%2BC3cXhsFamsrw%3D
37. TA Desai 2000 Micro- and nanoscale structures for tissue engineering constructs Med Eng Phys 22 9 595 606 10.1016/S1350-4533(00)00087-4 1:STN:280:DC%2BD3M7mt1WnsA%3D%3D
38. JD Kretlow AG Mikos 2007 Review: mineralization of synthetic polymer scaffolds for bone tissue engineering Tissue Eng 13 5 927 938 10.1089/ten.2006.0394 1:CAS:528:DC%2BD2sXltVKis7w%3D (Pubitemid 46870417)
39. JY Lim AD Dreiss Z Zhou JC Hansen CA Siedlecki RW Hengstebeck, et al. 2007 The regulation of integrin-mediated osteoblast focal adhesion and focal adhesion kinase expression by nanoscale topography Biomaterials 28 10 1787 1797 10.1016/j.biomaterials.2006.12.020 1:CAS:528:DC%2BD2sXpslSrtg%3D%3D (Pubitemid 46137997)
40. QP Pham U Sharma AG Mikos 2006 Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration Biomacromolecules 7 10 2796 2805 10.1021/bm060680j 1:CAS:528:DC%2BD28XpvVygtbo%3D (Pubitemid 44615263)
41. MM Stevens JH George 2005 Exploring and engineering the cell surface interface Science 310 5751 1135 1138 10.1126/science.1106587 1:CAS:528:DC%2BD2MXht1WgtLbE (Pubitemid 41681731)
42. G Balasundaram TJ Webster 2007 An overview of nano-polymers for orthopedic applications Macromol Biosci 7 5 635 642 10.1002/mabi.200600270 1:CAS:528:DC%2BD2sXlslSlsbc%3D (Pubitemid 47264637)
43. CP Barnes SA Sell ED Boland DG Simpson GL Bowlin 2007 Nanofiber technology: designing the next generation of tissue engineering scaffolds Adv Drug Deliv Rev 59 14 1413 1433 10.1016/j.addr.2007.04.022 1:CAS:528: DC%2BD2sXhtlCrtr7K (Pubitemid 350122771)
44. EM Christenson KS Anseth JJ van den Beucken CK Chan B Ercan JA Jansen, et al. 2007 Nanobiomaterial applications in orthopedics J Orthop Res 25 1 11 22 10.1002/jor.20305 1:CAS:528:DC%2BD2sXivVOks7g%3D (Pubitemid 46070727)
45. YW Chun TJ Webster 2009 The role of nanomedicine in growing tissues Ann Biomed Eng 37 10 2034 2047 10.1007/s10439-009-9722-1
46. MJ Dalby N Gadegaard R Tare A Andar MO Riehle P Herzyk, et al. 2007 The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder Nat Mater 6 12 997 1003 10.1038/nmat2013 1:CAS:528:DC%2BD2sXhtlOmtLrJ (Pubitemid 350210577)
47. K Jayaraman M Kotaki Y Zhang X Mo S Ramakrishna 2004 Recent advances in polymer nanofibers J Nanosci Nanotechnol 4 1-2 52 65 1:CAS:528: DC%2BD2cXivVynsbk%3D (Pubitemid 38594975)
48. LA Smith X Liu PX Ma 2008 Tissue engineering with nano-fibrous scaffolds Soft Matter 4 11 2144 2149 10.1039/b807088c 1:CAS:528:DC%2BD1cXhsFCqsL3K
49. G Wei P Ma 2008 Nanostructured biomaterials for regeneration Adv Funct Mater 18 3568 3582 10.1002/adfm.200800662 1:CAS:528:DC%2BD1cXhsVyqu77N
50. WE Teo W He S Ramakrishna 2006 Electrospun scaffold tailored for tissue-specific extracellular matrix Biotechnol J 1 9 918 929 10.1002/biot.200600044 1:CAS:528:DC%2BD28XhtFartrvL
51. Z Ma M Kotaki R Inai S Ramakrishna 2005 Potential of nanofiber matrix as tissue-engineering scaffolds Tissue Eng 11 1-2 101 109 10.1089/ten.2005.11.101 (Pubitemid 40515178)
52. DR Nisbet S Pattanawong NE Ritchie W Shen DI Finkelstein MK Horne, et al. 2007 Interaction of embryonic cortical neurons on nanofibrous scaffolds for neural tissue engineering J Neural Eng 4 2 35 41 10.1088/1741-2560/4/2/004 1:STN:280:DC%2BD2s3gs1Kjuw%3D%3D (Pubitemid 46603795)
53. V Guarino P Taddei M Di Foggia C Fagnano G Ciapetti L Ambrosio 2009 The influence of hydroxyapatite particles on in vitro degradation behavior of poly epsilon-caprolactone-based composite scaffolds Tissue Eng Part A 15 11 3655 3668 10.1089/ten.tea.2008.0543 1:CAS:528:DC%2BD1MXhsF2hsrzJ
54. SA Theron E Zussman AL Yarin 2004 Experimental investigation of the governing parameters in the electrospinning of polymer solutions Polymer 45 6 2017 2030 10.1016/j.polymer.2004.01.024 1:CAS:528:DC%2BD2cXhtlyjsbw%3D (Pubitemid 38224332)
55. A Muraglia I Martin R Cancedda R Quarto 1998 A nude mouse model for human bone formation in unloaded conditions Bone 22 5 Suppl 131S 134S 10.1016/S8756-3282(98)00009-X 1:STN:280:DyaK1c3mtFeqtA%3D%3D (Pubitemid 28223271)
56. K Anselme B Noel B Flautre MC Blary C Delecourt M Descamps, et al. 1999 Association of porous hydroxyapatite and bone marrow cells for bone regeneration Bone 25 2 Suppl 51S 54S 10.1016/S8756-3282(99)00133-7 1:CAS:528: DyaK1MXlsFGnsL4%3D (Pubitemid 29333179)
57. E Kon A Muraglia A Corsi P Bianco M Marcacci I Martin, et al. 2000 Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones J Biomed Mater Res 49 3 328 337 10.1002/(SICI)1097-4636(20000305)49:3<328::AID- JBM5>3.0.CO;2-Q 1:CAS:528:DC%2BD3cXltlCk (Pubitemid 30030478)
58. M Nishikawa A Myoui H Ohgushi M Ikeuchi N Tamai H Yoshikawa 2004 Bone tissue engineering using novel interconnected porous hydroxyapatite ceramics combined with marrow mesenchymal cells: quantitative and three-dimensional image analysis Cell Transpl 13 4 367 376 10.3727/000000004783983819 (Pubitemid 39163081)
59. M Thorwarth S Schultze-Mosgau P Kessler J Wiltfang KA Schlegel 2005 Bone regeneration in osseous defects using a resorbable nanoparticular hydroxyapatite J Oral Maxillofac Surg 63 11 1626 1633 10.1016/j.joms.2005.06.010 (Pubitemid 41525420)
60. H Yoshikawa A Myoui 2005 Bone tissue engineering with porous hydroxyapatite ceramics J Artif Organs 8 3 131 136 10.1007/s10047-005-0292-1 1:CAS:528:DC%2BD2MXhtFahur7P (Pubitemid 41464669)
61. TL Arinzeh T Tran J McAlary G Daculsi 2005 A comparative study of biphasic calcium phosphate ceramics for human mesenchymal stem-cell-induced bone formation Biomaterials 26 17 3631 3638 10.1016/j.biomaterials.2004.09.035 1:CAS:528:DC%2BD2cXhtFejsrvE (Pubitemid 40038157)
62. P Kasten R Luginbuhl M van Griensven T Barkhausen C Krettek M Bohner, et al. 2003 Comparison of human bone marrow stromal cells seeded on calcium-deficient hydroxyapatite, beta-tricalcium phosphate and demineralized bone matrix Biomaterials 24 15 2593 2603 10.1016/S0142-9612(03)00062-0 1:CAS:528:DC%2BD3sXjt1emu7o%3D (Pubitemid 36506482)
63. H Ohgushi Y Dohi S Tamai S Tabata 1993 Osteogenic differentiation of marrow stromal stem cells in porous hydroxyapatite ceramics J Biomed Mater Res 27 11 1401 1407 10.1002/jbm.820271107 1:CAS:528:DyaK2cXhslens78%3D (Pubitemid 23312631)
64. RJ Dekker JD de Bruijn M Stigter F Barrere P Layrolle CA van Blitterswijk 2005 Bone tissue engineering on amorphous carbonated apatite and crystalline octacalcium phosphate-coated titanium discs Biomaterials 26 25 5231 5239 10.1016/j.biomaterials.2005.01.057 1:CAS:528:DC%2BD2MXisFansrg%3D (Pubitemid 40387845)
65. E Landi S Sprio M Sandri G Celotti A Tampieri 2008 Development of Sr and CO3 co-substituted hydroxyapatites for biomedical applications Acta Biomater 4 3 656 663 10.1016/j.actbio.2007.10.010 1:CAS:528:DC%2BD1cXhtVarsrrL (Pubitemid 351461280)
66. J Tan WM Saltzman 2004 Biomaterials with hierarchically defined micro- and nanoscale structure Biomaterials 25 17 3593 3601 10.1016/j.biomaterials. 2003.10.034 1:CAS:528:DC%2BD2cXitVKjur4%3D (Pubitemid 38327047)
67. G Mendonca DB Mendonca LG Simoes AL Araujo ER Leite WR Duarte, et al. 2009 The effects of implant surface nanoscale features on osteoblast-specific gene expression Biomaterials 30 25 4053 4062 10.1016/j.biomaterials.2009.04.010 1:CAS:528:DC%2BD1MXotlOktr0%3D
68. TJ Webster C Ergun RH Doremus RW Siegel R Bizios 2000 Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics J Biomed Mater Res 51 3 475 483 10.1002/1097-4636(20000905)51:3<475::AID-JBM23>3.0.CO;2-9 1:CAS:528:DC%2BD3cXkslagtL4%3D (Pubitemid 30452152)
69. MJ Biggs RG Richards N Gadegaard CD Wilkinson RO Oreffo MJ Dalby 2009 The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells Biomaterials 30 28 5094 5103 10.1016/j.biomaterials.2009.05.049 1:CAS:528:DC%2BD1MXpt1Citrk%3D
70. R James US Toti CT Laurencin SG Kumbar 2011 Electrospun nanofibrous scaffolds for engineering soft connective tissues Methods Mol Biol 726 243 258 10.1007/978-1-61779-052-2-16 1:CAS:528:DC%2BC3MXmvVahs7o%3D
71. R Vasita DS Katti 2006 Nanofibers and their applications in tissue engineering Int J Nanomed 1 1 15 30 10.2147/nano.2006.1.1.15 1:CAS:528:DC%2BD28XhtFSjsrrE
72. AS Curtis M Dalby N Gadegaard 2006 Cell signaling arising from nanotopography: implications for nanomedical devices Nanomedicine (Lond) 1 1 67 72 10.2217/17435889.1.1.67 1:CAS:528:DC%2BD28XpsFGhtrk%3D
73. S Schenk V Quaranta 2003 Tales from the crypt[ic] sites of the extracellular matrix Trends Cell Biol 13 7 366 375 10.1016/S0962-8924(03)00129-6 1:CAS:528:DC%2BD3sXkvFGku7o%3D (Pubitemid 36776714)