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Volumn 5, Issue 2, 2012, Pages 111-125

Efficacy and safety of the probiotic Saccharomyces boulardii for the prevention and therapy of gastrointestinal disorders

Author keywords

Efficacy; Gastrointestinal disorders; Probiotic; Saccharomyces boulardii; Safety

Indexed keywords

FLUCONAZOLE; MEBEVERINE; MESALAZINE; METRONIDAZOLE; PLACEBO; PROBIOTIC AGENT;

EID: 84857520779     PISSN: 1756283X     EISSN: 17562648     Source Type: Journal    
DOI: 10.1177/1756283X11428502     Document Type: Review
Times cited : (258)

References (134)
  • 1
    • 51049116216 scopus 로고    scopus 로고
    • Molecular analysis of the digestive microbiota in a gnotobiotic mouse model during antibiotic treatment: Influence of Saccharomyces boulardii
    • Barc M.C. Charrin-Sarnel C. Rochet V. Bourlioux F. Sandre C. Boureau H. et al. (2008) Molecular analysis of the digestive microbiota in a gnotobiotic mouse model during antibiotic treatment: Influence of Saccharomyces boulardii. Anaerobe 14: 229–233.
    • (2008) Anaerobe , vol.14 , pp. 229-233
    • Barc, M.C.1    Charrin-Sarnel, C.2    Rochet, V.3    Bourlioux, F.4    Sandre, C.5    Boureau, H.6
  • 2
    • 0037204196 scopus 로고    scopus 로고
    • Clinical practice. Antibiotic-associated diarrhea
    • Bartlett J.G. (2002) Clinical practice. Antibiotic-associated diarrhea. N Engl J Med 346: 334–339.
    • (2002) N Engl J Med , vol.346 , pp. 334-339
    • Bartlett, J.G.1
  • 3
    • 84855695088 scopus 로고
    • Randomised trial of Saccharomyces boulardii in the treatment of functional colon disorders
    • Bennani A. (1990) Randomised trial of Saccharomyces boulardii in the treatment of functional colon disorders. L'Objectif Medical 73: 56–61.
    • (1990) L'Objectif Medical , vol.73 , pp. 56-61
    • Bennani, A.1
  • 6
    • 77950354453 scopus 로고    scopus 로고
    • Preventive effects of different probiotic formulations on travelers’ diarrhea model in Wistar rats: preventive effects of probiotics on TD
    • Bisson J.F. Hidalgo S. Rozan P. Messaoudi M. (2010) Preventive effects of different probiotic formulations on travelers’ diarrhea model in Wistar rats: preventive effects of probiotics on TD. Dig Dis Sci 55: 911–919.
    • (2010) Dig Dis Sci , vol.55 , pp. 911-919
    • Bisson, J.F.1    Hidalgo, S.2    Rozan, P.3    Messaoudi, M.4
  • 7
    • 0024320219 scopus 로고
    • Disposition kinetics of Saccharomyces boulardii in man and rat
    • Blehaut H. Massot J. Elmer G.W. Levy R.H. (1989) Disposition kinetics of Saccharomyces boulardii in man and rat. Biopharm Drug Dispos 10: 353–364.
    • (1989) Biopharm Drug Dispos , vol.10 , pp. 353-364
    • Blehaut, H.1    Massot, J.2    Elmer, G.W.3    Levy, R.H.4
  • 8
    • 0030958897 scopus 로고    scopus 로고
    • Saccharomyces boulardii prevents diarrhea in critically ill tube-fed patients. A multicenter, randomized, double-blind placebo-controlled trial
    • Bleichner G. Blehaut H. Mentec H. Moyse D. (1997) Saccharomyces boulardii prevents diarrhea in critically ill tube-fed patients. A multicenter, randomized, double-blind placebo-controlled trial. Intensive Care Med 23: 517–523.
    • (1997) Intensive Care Med , vol.23 , pp. 517-523
    • Bleichner, G.1    Blehaut, H.2    Mentec, H.3    Moyse, D.4
  • 10
    • 0034076678 scopus 로고    scopus 로고
    • Application of the colon-simulation technique for studying the effects of Saccharomyces boulardii on basic parameters of porcine cecal microbial metabolism disturbed by clindamycin
    • Breves G. Faul K. Schroder B. Holst H. Caspary W.F. Stein J. (2000) Application of the colon-simulation technique for studying the effects of Saccharomyces boulardii on basic parameters of porcine cecal microbial metabolism disturbed by clindamycin. Digestion 61: 193–200.
    • (2000) Digestion , vol.61 , pp. 193-200
    • Breves, G.1    Faul, K.2    Schroder, B.3    Holst, H.4    Caspary, W.F.5    Stein, J.6
  • 11
    • 13644254969 scopus 로고    scopus 로고
    • Saccharomyces boulardii induced sepsis: successful therapy with voriconazole after treatment failure with fluconazole
    • Burkhardt O. Kohnlein T. Pletz M. Welte T. (2005) Saccharomyces boulardii induced sepsis: successful therapy with voriconazole after treatment failure with fluconazole. Scand J Infect Dis 37: 69–72.
    • (2005) Scand J Infect Dis , vol.37 , pp. 69-72
    • Burkhardt, O.1    Kohnlein, T.2    Pletz, M.3    Welte, T.4
  • 12
    • 58149302567 scopus 로고    scopus 로고
    • Twenty-five years of research on Saccharomyces boulardii trophic effects: updates and perspectives
    • Buts J.P. (2009) Twenty-five years of research on Saccharomyces boulardii trophic effects: updates and perspectives. Dig Dis Sci 54: 15–18.
    • (2009) Dig Dis Sci , vol.54 , pp. 15-18
    • Buts, J.P.1
  • 13
    • 0025181832 scopus 로고
    • Stimulation of secretory IgA and secretory component of immunoglobulins in small intestine of rats treated with Saccharomyces boulardii
    • Buts J.P. Bernasconi P. Vaerman J.P. Dive C. (1990) Stimulation of secretory IgA and secretory component of immunoglobulins in small intestine of rats treated with Saccharomyces boulardii. Dig Dis Sci 35: 251–256.
    • (1990) Dig Dis Sci , vol.35 , pp. 251-256
    • Buts, J.P.1    Bernasconi, P.2    Vaerman, J.P.3    Dive, C.4
  • 14
    • 0022654794 scopus 로고
    • Response of human and rat small intestinal mucosa to oral administration of Saccharomyces boulardii
    • Buts J.P. Bernasconi P. van Craynest M.P. Maldague P. De M.R. (1986) Response of human and rat small intestinal mucosa to oral administration of Saccharomyces boulardii. Pediatr Res 20: 192–196.
    • (1986) Pediatr Res , vol.20 , pp. 192-196
    • Buts, J.P.1    Bernasconi, P.2    van Craynest, M.P.3    Maldague, P.4    De, M.R.5
  • 15
    • 0027251381 scopus 로고
    • Saccharomyces boulardii for Clostridium difficile-associated enteropathies in infants
    • Buts J.P. Corthier G. Delmee M. (1993) Saccharomyces boulardii for Clostridium difficile-associated enteropathies in infants. J Pediatr Gastroenterol Nutr 16: 419–425.
    • (1993) J Pediatr Gastroenterol Nutr , vol.16 , pp. 419-425
    • Buts, J.P.1    Corthier, G.2    Delmee, M.3
  • 16
    • 0027983624 scopus 로고
    • Saccharomyces boulardii enhances rat intestinal enzyme expression by endoluminal release of polyamines
    • Buts J.P. De K.N. De R.L. (1994) Saccharomyces boulardii enhances rat intestinal enzyme expression by endoluminal release of polyamines. Pediatr Res 36: 522–527.
    • (1994) Pediatr Res , vol.36 , pp. 522-527
    • Buts, J.P.1    De, K.N.2    De, R.L.3
  • 17
    • 0032966439 scopus 로고    scopus 로고
    • Saccharomyces boulardii upgrades cellular adaptation after proximal enterectomy in rats
    • Buts J.P. De K.N. Marandi S. Hermans D. Sokal E.M. Chae Y.H. et al. (1999) Saccharomyces boulardii upgrades cellular adaptation after proximal enterectomy in rats. Gut 45: 89–96.
    • (1999) Gut , vol.45 , pp. 89-96
    • Buts, J.P.1    De, K.N.2    Marandi, S.3    Hermans, D.4    Sokal, E.M.5    Chae, Y.H.6
  • 18
    • 0036210510 scopus 로고    scopus 로고
    • Saccharomyces boulardii enhances N-terminal peptide hydrolysis in suckling rat small intestine by endoluminal release of a zinc-binding metalloprotease
    • Buts J.P. De K.N. Stilmant C. Sokal E. Marandi S. (2002) Saccharomyces boulardii enhances N-terminal peptide hydrolysis in suckling rat small intestine by endoluminal release of a zinc-binding metalloprotease. Pediatr Res 51: 528–534.
    • (2002) Pediatr Res , vol.51 , pp. 528-534
    • Buts, J.P.1    De, K.N.2    Stilmant, C.3    Sokal, E.4    Marandi, S.5
  • 19
    • 33748075169 scopus 로고    scopus 로고
    • Saccharomyces boulardii produces in rat small intestine a novel protein phosphatase that inhibits Escherichia coli endotoxin by dephosphorylation
    • Buts J.P. Dekeyser N. Stilmant C. Delem E. Smets F. Sokal E. (2006) Saccharomyces boulardii produces in rat small intestine a novel protein phosphatase that inhibits Escherichia coli endotoxin by dephosphorylation. Pediatr Res 60: 24–29.
    • (2006) Pediatr Res , vol.60 , pp. 24-29
    • Buts, J.P.1    Dekeyser, N.2    Stilmant, C.3    Delem, E.4    Smets, F.5    Sokal, E.6
  • 20
    • 0031967088 scopus 로고    scopus 로고
    • Premature stimulation of rat sucrase-isomaltase (SI) by exogenous insulin and the analog B-Asp10 is regulated by a receptor-mediated signal triggering SI gene transcription
    • Buts J.P. Duranton B. De K.N. Sokal E.M. Maernhout A.S. Raul F. et al. (1998) Premature stimulation of rat sucrase-isomaltase (SI) by exogenous insulin and the analog B-Asp10 is regulated by a receptor-mediated signal triggering SI gene transcription. Pediatr Res 43: 585–591.
    • (1998) Pediatr Res , vol.43 , pp. 585-591
    • Buts, J.P.1    Duranton, B.2    De, K.N.3    Sokal, E.M.4    Maernhout, A.S.5    Raul, F.6
  • 22
    • 84866629141 scopus 로고    scopus 로고
    • Clinical utility of probiotics in inflammatory bowel disease
    • Cain A.M. Karpa K.D. (2011) Clinical utility of probiotics in inflammatory bowel disease. Altern Ther Health Med 17: 72–79.
    • (2011) Altern Ther Health Med , vol.17 , pp. 72-79
    • Cain, A.M.1    Karpa, K.D.2
  • 23
    • 33645544410 scopus 로고    scopus 로고
    • Prophylactic Saccharomyces boulardii in the prevention of antibiotic-associated diarrhea: a prospective study
    • Can M. Besirbellioglu B.A. Avci I.Y. Beker C.M. Pahsa A. (2006) Prophylactic Saccharomyces boulardii in the prevention of antibiotic-associated diarrhea: a prospective study. Med Sci Monit 12: I19-I22.
    • (2006) Med Sci Monit , vol.12 , pp. I19-I22
    • Can, M.1    Besirbellioglu, B.A.2    Avci, I.Y.3    Beker, C.M.4    Pahsa, A.5
  • 24
    • 34548165542 scopus 로고    scopus 로고
    • Probiotics for treatment of acute diarrhoea in children: randomised clinical trial of five different preparations
    • Canani R.B. Cirillo P. Terrin G. Cesarano L. Spagnuolo M.I. De V.A. et al. (2007) Probiotics for treatment of acute diarrhoea in children: randomised clinical trial of five different preparations. BMJ 335: 340.
    • (2007) BMJ , vol.335 , pp. 340
    • Canani, R.B.1    Cirillo, P.2    Terrin, G.3    Cesarano, L.4    Spagnuolo, M.I.5    De, V.A.6
  • 25
    • 0027302362 scopus 로고
    • Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers
    • Canil C. Rosenshine I. Ruschkowski S. Donnenberg M.S. Kaper J.B. Finlay B.B. (1993) Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers. Infect Immun 61: 2755–2762.
    • (1993) Infect Immun , vol.61 , pp. 2755-2762
    • Canil, C.1    Rosenshine, I.2    Ruschkowski, S.3    Donnenberg, M.S.4    Kaper, J.B.5    Finlay, B.B.6
  • 26
    • 79953661081 scopus 로고    scopus 로고
    • Saccharomyces boulardii improves intestinal cell restitution through activation of the alpha2beta1 integrin collagen receptor
    • Canonici A. Siret C. Pellegrino E. Pontier-Bres R. Pouyet L. Montero M.P. et al. (2011) Saccharomyces boulardii improves intestinal cell restitution through activation of the alpha2beta1 integrin collagen receptor. PloS ONE 6: e18427.
    • (2011) PloS ONE , vol.6 , pp. e18427
    • Canonici, A.1    Siret, C.2    Pellegrino, E.3    Pontier-Bres, R.4    Pouyet, L.5    Montero, M.P.6
  • 27
    • 10544226189 scopus 로고    scopus 로고
    • Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum
    • Castagliuolo I. La Mont J.T. Nikulasson S.T. Pothoulakis C. (1996) Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum. Infect Immun 64: 5225–5232.
    • (1996) Infect Immun , vol.64 , pp. 5225-5232
    • Castagliuolo, I.1    La Mont, J.T.2    Nikulasson, S.T.3    Pothoulakis, C.4
  • 28
    • 0032919855 scopus 로고    scopus 로고
    • Saccharomyces boulardii protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa
    • Castagliuolo I. Riegler M.F. Valenick L. La Mont J.T. Pothoulakis C. (1999) Saccharomyces boulardii protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa. Infect Immun 67: 302–307.
    • (1999) Infect Immun , vol.67 , pp. 302-307
    • Castagliuolo, I.1    Riegler, M.F.2    Valenick, L.3    La Mont, J.T.4    Pothoulakis, C.5
  • 29
    • 35648945470 scopus 로고
    • Effects of Saccharomyces boulardii in children with chronic diarrhea, especially cases due to giardiasis
    • Castaneda C. Garcia E. Santa Cruz M. Fernandez M. Monterrey P. (1995) Effects of Saccharomyces boulardii in children with chronic diarrhea, especially cases due to giardiasis. Rev Mex Pueric Pediatr 2: 12–16.
    • (1995) Rev Mex Pueric Pediatr , vol.2 , pp. 12-16
    • Castaneda, C.1    Garcia, E.2    Santa Cruz, M.3    Fernandez, M.4    Monterrey, P.5
  • 30
    • 0025362542 scopus 로고
    • Prevention of Clostridium difficile-induced experimental pseudomembranous colitis by Saccharomyces boulardii: a scanning electron microscopic and microbiological study
    • Castex F. Corthier G. Jouvert S. Elmer G.W. Lucas F. Bastide M. (1990) Prevention of Clostridium difficile-induced experimental pseudomembranous colitis by Saccharomyces boulardii: a scanning electron microscopic and microbiological study. J Gen Microbiol 136: 1085–1089.
    • (1990) J Gen Microbiol , vol.136 , pp. 1085-1089
    • Castex, F.1    Corthier, G.2    Jouvert, S.3    Elmer, G.W.4    Lucas, F.5    Bastide, M.6
  • 31
    • 33747699728 scopus 로고    scopus 로고
    • Saccharomyces boulardii inhibits ERK1/2 mitogen-activated protein kinase activation both in vitro and in vivo and protects against Clostridium difficile toxin A-induced enteritis
    • Chen X. Kokkotou E.G. Mustafa N. Bhaskar K.R. Sougioultzis S. O'Brien M. et al. (2006) Saccharomyces boulardii inhibits ERK1/2 mitogen-activated protein kinase activation both in vitro and in vivo and protects against Clostridium difficile toxin A-induced enteritis. J Biol Chem 281: 24449–24454.
    • (2006) J Biol Chem , vol.281 , pp. 24449-24454
    • Chen, X.1    Kokkotou, E.G.2    Mustafa, N.3    Bhaskar, K.R.4    Sougioultzis, S.5    O'Brien, M.6
  • 32
    • 80052037138 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled multicenter trial of Saccharomyces boulardii in irritable bowel syndrome: effect on quality of life
    • in press
    • Choi C.H. Jo S.Y. Park H.J. Chang S.K. Byeon J.S. Myung S.J. (2011) A randomized, double-blind, placebo-controlled multicenter trial of Saccharomyces boulardii in irritable bowel syndrome: effect on quality of life. J Clin Gastroenterol, in press.
    • (2011) J Clin Gastroenterol
    • Choi, C.H.1    Jo, S.Y.2    Park, H.J.3    Chang, S.K.4    Byeon, J.S.5    Myung, S.J.6
  • 33
    • 34547569295 scopus 로고    scopus 로고
    • Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study
    • Cindoruk M. Erkan G. Karakan T. Dursun A. Unal S. (2007) Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study. Helicobacter 12: 309–316.
    • (2007) Helicobacter , vol.12 , pp. 309-316
    • Cindoruk, M.1    Erkan, G.2    Karakan, T.3    Dursun, A.4    Unal, S.5
  • 34
    • 77951026738 scopus 로고    scopus 로고
    • Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA)
    • Cohen S.H. Gerding D.N. Johnson S. Kelly C.P. Loo V.G. McDonald L.C. et al. (2010) Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol 31: 431–455.
    • (2010) Infect Control Hosp Epidemiol , vol.31 , pp. 431-455
    • Cohen, S.H.1    Gerding, D.N.2    Johnson, S.3    Kelly, C.P.4    Loo, V.G.5    McDonald, L.C.6
  • 35
    • 0036840803 scopus 로고    scopus 로고
    • Effect of different probiotic preparations on anti-Helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study
    • Cremonini F. Di C.S. Covino M. Armuzzi A. Gabrielli M. Santarelli L. et al. (2002) Effect of different probiotic preparations on anti-Helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study. Am J Gastroenterol 97: 2744–2749.
    • (2002) Am J Gastroenterol , vol.97 , pp. 2744-2749
    • Cremonini, F.1    Di, C.S.2    Covino, M.3    Armuzzi, A.4    Gabrielli, M.5    Santarelli, L.6
  • 36
    • 0033806709 scopus 로고    scopus 로고
    • Saccharomyces boulardii preserves the barrier function and modulates the signal transduction pathway induced in enteropathogenic Escherichia coli-infected T 84 cells
    • Czerucka D. Dahan S. Mograbi B. Rossi B. Rampal P. (2000) Saccharomyces boulardii preserves the barrier function and modulates the signal transduction pathway induced in enteropathogenic Escherichia coli-infected T 84 cells. Infect Immun 68: 5998–6004.
    • (2000) Infect Immun , vol.68 , pp. 5998-6004
    • Czerucka, D.1    Dahan, S.2    Mograbi, B.3    Rossi, B.4    Rampal, P.5
  • 37
    • 34548303882 scopus 로고    scopus 로고
    • Review article: yeast as probiotics – Saccharomyces boulardii
    • Czerucka D. Piche T. Rampal P. (2007) Review article: yeast as probiotics – Saccharomyces boulardii. Aliment Pharmacol Ther 26: 767–778.
    • (2007) Aliment Pharmacol Ther , vol.26 , pp. 767-778
    • Czerucka, D.1    Piche, T.2    Rampal, P.3
  • 38
    • 0036286070 scopus 로고    scopus 로고
    • Experimental effects of Saccharomyces boulardii on diarrheal pathogens
    • Czerucka D. Rampal P. (2002) Experimental effects of Saccharomyces boulardii on diarrheal pathogens. Microbes Infect 4: 733–739.
    • (2002) Microbes Infect , vol.4 , pp. 733-739
    • Czerucka, D.1    Rampal, P.2
  • 39
    • 0028107147 scopus 로고
    • Saccharomyces boulardii inhibits secretagogue-mediated adenosine 3’,5’-cyclic monophosphate induction in intestinal cells
    • Czerucka D. Roux I. Rampal P. (1994) Saccharomyces boulardii inhibits secretagogue-mediated adenosine 3’,5’-cyclic monophosphate induction in intestinal cells. Gastroenterology 106: 65–72.
    • (1994) Gastroenterology , vol.106 , pp. 65-72
    • Czerucka, D.1    Roux, I.2    Rampal, P.3
  • 40
    • 0036123679 scopus 로고    scopus 로고
    • Enterohemorrhagic Escherichia coli infection induces interleukin-8 production via activation of mitogen-activated protein kinases and the transcription factors NF-kappa B and AP-1 in T 84 cells
    • Dahan S. Busuttil V. Imbert V. Peyron J.F. Rampal P. Czerucka D. (2002) Enterohemorrhagic Escherichia coli infection induces interleukin-8 production via activation of mitogen-activated protein kinases and the transcription factors NF-kappa B and AP-1 in T 84 cells. Infect Immun 70: 2304–2310.
    • (2002) Infect Immun , vol.70 , pp. 2304-2310
    • Dahan, S.1    Busuttil, V.2    Imbert, V.3    Peyron, J.F.4    Rampal, P.5    Czerucka, D.6
  • 41
    • 0037304989 scopus 로고    scopus 로고
    • Saccharomyces boulardii interferes with enterohemorrhagic Escherichia coli-induced signaling pathways in T 84 cells
    • Dahan S. Dalmasso G. Imbert V. Peyron J.F. Rampal P. Czerucka D. (2003) Saccharomyces boulardii interferes with enterohemorrhagic Escherichia coli-induced signaling pathways in T 84 cells. Infect Immun 71:766–773.
    • (2003) Infect Immun , vol.71 , pp. 766-773
    • Dahan, S.1    Dalmasso, G.2    Imbert, V.3    Peyron, J.F.4    Rampal, P.5    Czerucka, D.6
  • 42
    • 33845683428 scopus 로고    scopus 로고
    • Saccharomyces boulardii inhibits inflammatory bowel disease by trapping T cells in mesenteric lymph nodes
    • Dalmasso G. Cottrez F. Imbert V. Lagadec P. Peyron J.F. Rampal P. et al. (2006 a) Saccharomyces boulardii inhibits inflammatory bowel disease by trapping T cells in mesenteric lymph nodes. Gastroenterology 131: 1812–1825.
    • (2006) Gastroenterology , vol.131 , pp. 1812-1825
    • Dalmasso, G.1    Cottrez, F.2    Imbert, V.3    Lagadec, P.4    Peyron, J.F.5    Rampal, P.6
  • 43
    • 33744827083 scopus 로고    scopus 로고
    • Saccharomyces boulardii prevents TNF-alpha-induced apoptosis in EHEC-infected T 84 cells
    • Dalmasso G. Loubat A. Dahan S. Calle G. Rampal P. Czerucka D. (2006 b) Saccharomyces boulardii prevents TNF-alpha-induced apoptosis in EHEC-infected T 84 cells. Res Microbiol 157: 456–465.
    • (2006) Res Microbiol , vol.157 , pp. 456-465
    • Dalmasso, G.1    Loubat, A.2    Dahan, S.3    Calle, G.4    Rampal, P.5    Czerucka, D.6
  • 44
    • 79955941227 scopus 로고    scopus 로고
    • Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection
    • Dinleyici E.C. Eren M. Dogan N. Reyhanioglu S. Yargic Z.A. Vandenplas Y. (2011) Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection. Parasitol Res 108: 541–545.
    • (2011) Parasitol Res , vol.108 , pp. 541-545
    • Dinleyici, E.C.1    Eren, M.2    Dogan, N.3    Reyhanioglu, S.4    Yargic, Z.A.5    Vandenplas, Y.6
  • 45
    • 66949125043 scopus 로고    scopus 로고
    • Clinical efficacy of Saccharomyces boulardii and metronidazole compared with metronidazole alone in children with acute bloody diarrhea caused by amebiasis: a prospective, randomized, open label study
    • Dinleyici E.C. Eren M. Yargic Z.A. Dogan N. Vandenplas Y. (2009) Clinical efficacy of Saccharomyces boulardii and metronidazole compared with metronidazole alone in children with acute bloody diarrhea caused by amebiasis: a prospective, randomized, open label study. Am J Trop Med Hyg 80: 953–955.
    • (2009) Am J Trop Med Hyg , vol.80 , pp. 953-955
    • Dinleyici, E.C.1    Eren, M.2    Yargic, Z.A.3    Dogan, N.4    Vandenplas, Y.5
  • 46
    • 29244491643 scopus 로고    scopus 로고
    • Efficacy and safety of Saccharomyces boulardii in prevention of antibiotic-associated diarrhoea due to Helicobacter pylori eradication
    • Duman D.G. Bor S. Ozutemiz O. Sahin T. Oguz D. Istan F. et al. (2005) Efficacy and safety of Saccharomyces boulardii in prevention of antibiotic-associated diarrhoea due to Helicobacter pylori eradication. Eur J Gastroenterol Hepatol 17: 1357–1361.
    • (2005) Eur J Gastroenterol Hepatol , vol.17 , pp. 1357-1361
    • Duman, D.G.1    Bor, S.2    Ozutemiz, O.3    Sahin, T.4    Oguz, D.5    Istan, F.6
  • 47
    • 0025855332 scopus 로고
    • Modulation of Clostridium difficile induced mortality as a function of the dose and the viability of the Saccharomyces boulardii used as a preventative agent in gnotobiotic mice
    • Elmer G.W. Corthier G. (1991) Modulation of Clostridium difficile induced mortality as a function of the dose and the viability of the Saccharomyces boulardii used as a preventative agent in gnotobiotic mice. Can J Microbiol 37: 315–317.
    • (1991) Can J Microbiol , vol.37 , pp. 315-317
    • Elmer, G.W.1    Corthier, G.2
  • 48
    • 0032999029 scopus 로고    scopus 로고
    • Survival of Saccharomyces boulardii in the rat gastrointestinal tract and effects of dietary fiber
    • Elmer G.W. Martin S.W. Horner K.L. McFarland L.V. Levy R.H. (1999 a) Survival of Saccharomyces boulardii in the rat gastrointestinal tract and effects of dietary fiber. Microb Ecology Health Dis 11: 29–34.
    • (1999) Microb Ecology Health Dis , vol.11 , pp. 29-34
    • Elmer, G.W.1    Martin, S.W.2    Horner, K.L.3    McFarland, L.V.4    Levy, R.H.5
  • 50
    • 0002062238 scopus 로고
    • Evaluation of Saccharomyces boulardii for patients with HIV-related chronic diarrhoea and in healthy volunteers receiving antifungals
    • Elmer G.W. Moyer K.A. Vega R. Surawicz C.M. Collier A.C. Hooton T.M. et al. (1995) Evaluation of Saccharomyces boulardii for patients with HIV-related chronic diarrhoea and in healthy volunteers receiving antifungals. Microb Ther 25: 23–31.
    • (1995) Microb Ther , vol.25 , pp. 23-31
    • Elmer, G.W.1    Moyer, K.A.2    Vega, R.3    Surawicz, C.M.4    Collier, A.C.5    Hooton, T.M.6
  • 51
    • 57649142986 scopus 로고    scopus 로고
    • Effects of Saccharomyces boulardii on cytokine secretion from intraepithelial lymphocytes infected by Escherichia coli and Candida albicans
    • Fidan I. Kalkanci A. Yesilyurt E. Yalcin B. Erdal B. Kustimur S. et al. (2009) Effects of Saccharomyces boulardii on cytokine secretion from intraepithelial lymphocytes infected by Escherichia coli and Candida albicans. Mycoses 52: 29–34.
    • (2009) Mycoses , vol.52 , pp. 29-34
    • Fidan, I.1    Kalkanci, A.2    Yesilyurt, E.3    Yalcin, B.4    Erdal, B.5    Kustimur, S.6
  • 53
    • 0141428050 scopus 로고    scopus 로고
    • Effect of Lactobacillus strains and Saccharomyces boulardii on persistent diarrhea in children
    • Gaon D. Garcia H. Winter L. (2003) Effect of Lactobacillus strains and Saccharomyces boulardii on persistent diarrhea in children. Medicina (B Aires) 63: 293–298.
    • (2003) Medicina (B Aires) , vol.63 , pp. 293-298
    • Gaon, D.1    Garcia, H.2    Winter, L.3
  • 55
  • 56
    • 0032807013 scopus 로고    scopus 로고
    • Adherence of Escherichia coli serogroup O 157 and the Salmonella typhimurium mutant DT 104 to the surface of Saccharomyces boulardii
    • Gedek B.R. (1999 a) Adherence of Escherichia coli serogroup O 157 and the Salmonella typhimurium mutant DT 104 to the surface of Saccharomyces boulardii. Mycoses 42: 261–264.
    • (1999) Mycoses , vol.42 , pp. 261-264
    • Gedek, B.R.1
  • 57
    • 0032807013 scopus 로고    scopus 로고
    • Adherence of Escherichia coli serogroup O 157 and the Salmonella typhimurium mutant DT 104 to the surface of Saccharomyces boulardii
    • Gedek B.R. (1999 b) Adherence of Escherichia coli serogroup O 157 and the Salmonella typhimurium mutant DT 104 to the surface of Saccharomyces boulardii. Mycoses 42: 261–264.
    • (1999) Mycoses , vol.42 , pp. 261-264
    • Gedek, B.R.1
  • 58
    • 80052540085 scopus 로고    scopus 로고
    • Protection against increased intestinal permeability and bacterial translocation induced by intestinal obstruction in mice treated with viable and heat-killed Saccharomyces boulardii
    • Generoso S.V. Viana M.L. Santos R.G. Arantes R.M. Martins F.S. Nicoli J.R. et al. (2011) Protection against increased intestinal permeability and bacterial translocation induced by intestinal obstruction in mice treated with viable and heat-killed Saccharomyces boulardii. Eur J Nutr 50: 261–269.
    • (2011) Eur J Nutr , vol.50 , pp. 261-269
    • Generoso, S.V.1    Viana, M.L.2    Santos, R.G.3    Arantes, R.M.4    Martins, F.S.5    Nicoli, J.R.6
  • 59
    • 33644958017 scopus 로고    scopus 로고
    • The effects of Saccharomyces boulardii on bacterial translocation in rats with obstructive jaundice
    • Geyik M.F. Aldemir M. Hosoglu S. Ayaz C. Satilmis S. Buyukbayram H. et al. (2006) The effects of Saccharomyces boulardii on bacterial translocation in rats with obstructive jaundice. Ann R Coll Surg Engl 88: 176–180.
    • (2006) Ann R Coll Surg Engl , vol.88 , pp. 176-180
    • Geyik, M.F.1    Aldemir, M.2    Hosoglu, S.3    Ayaz, C.4    Satilmis, S.5    Buyukbayram, H.6
  • 60
    • 26644452974 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase involvement in the mechanism of action of Saccharomyces boulardii in castor oil-induced diarrhoea in rats
    • Girard P. Pansart Y. Gillardin J.M. (2005) Inducible nitric oxide synthase involvement in the mechanism of action of Saccharomyces boulardii in castor oil-induced diarrhoea in rats. Nitric Oxide 13: 163–169.
    • (2005) Nitric Oxide , vol.13 , pp. 163-169
    • Girard, P.1    Pansart, Y.2    Gillardin, J.M.3
  • 61
    • 0033981537 scopus 로고    scopus 로고
    • Probiotics and gastrointestinal health
    • Gorbach S.L. (2000) Probiotics and gastrointestinal health. Am J Gastroenterol 95: S2-S4.
    • (2000) Am J Gastroenterol , vol.95 , pp. S2-S4
    • Gorbach, S.L.1
  • 62
    • 31544472891 scopus 로고    scopus 로고
    • Effect of regular ingestion of Saccharomyces boulardii plus inulin or Lactobacillus acidophilus LB in children colonized by Helicobacter pylori
    • Gotteland M. Poliak L. Cruchet S. Brunser O. (2005) Effect of regular ingestion of Saccharomyces boulardii plus inulin or Lactobacillus acidophilus LB in children colonized by Helicobacter pylori. Acta Paediatr 94: 1747–1751.
    • (2005) Acta Paediatr , vol.94 , pp. 1747-1751
    • Gotteland, M.1    Poliak, L.2    Cruchet, S.3    Brunser, O.4
  • 63
    • 38849083178 scopus 로고    scopus 로고
    • Formulations for protecting the probiotic Saccharomyces boulardii from degradation in acidic condition
    • Graff S. Chaumeil J.C. Boy P. Lai-Kuen R. Charrueau C. (2008 a) Formulations for protecting the probiotic Saccharomyces boulardii from degradation in acidic condition. Biol Pharm Bull 31: 266–272.
    • (2008) Biol Pharm Bull , vol.31 , pp. 266-272
    • Graff, S.1    Chaumeil, J.C.2    Boy, P.3    Lai-Kuen, R.4    Charrueau, C.5
  • 64
    • 52649145404 scopus 로고    scopus 로고
    • Influence of pH conditions on the viability of Saccharomyces boulardii yeast
    • Graff S. Chaumeil J.C. Boy P. Lai-Kuen R. Charrueau C. (2008 b) Influence of pH conditions on the viability of Saccharomyces boulardii yeast. J Gen Appl Microbiol 54: 221–227.
    • (2008) J Gen Appl Microbiol , vol.54 , pp. 221-227
    • Graff, S.1    Chaumeil, J.C.2    Boy, P.3    Lai-Kuen, R.4    Charrueau, C.5
  • 65
    • 43149117068 scopus 로고    scopus 로고
    • European Society for Paediatric Gastroenterology, Hepatology, and Nutrition/European Society for Paediatric Infectious Diseases evidence-based guidelines for the management of acute gastroenteritis in children in Europe
    • Suppl. 2
    • Guarino A. Albano F. Ashkenazi S. Gendrel D. Hoekstra J.H. Shamir R. et al. (2008) European Society for Paediatric Gastroenterology, Hepatology, and Nutrition/European Society for Paediatric Infectious Diseases evidence-based guidelines for the management of acute gastroenteritis in children in Europe. J Pediatr Gastroenterol Nutr 46(Suppl. 2): S81–S122.
    • (2008) J Pediatr Gastroenterol Nutr , vol.46 , pp. S81-S122
    • Guarino, A.1    Albano, F.2    Ashkenazi, S.3    Gendrel, D.4    Hoekstra, J.H.5    Shamir, R.6
  • 66
    • 77951730354 scopus 로고    scopus 로고
    • Saccharomyces boulardii plus rifaximin in mesalamine-intolerant ulcerative colitis
    • Guslandi M. (2010) Saccharomyces boulardii plus rifaximin in mesalamine-intolerant ulcerative colitis. J Clin Gastroenterol 44:385.
    • (2010) J Clin Gastroenterol , vol.44 , pp. 385
    • Guslandi, M.1
  • 67
    • 80052023887 scopus 로고    scopus 로고
    • Treatment of irritable bowel syndrome with Saccharomyces boulardii
    • in press
    • Guslandi M. (2011) Treatment of irritable bowel syndrome with Saccharomyces boulardii. J Clin Gastroenterol, in press.
    • (2011) J Clin Gastroenterol
    • Guslandi, M.1
  • 68
    • 0037783259 scopus 로고    scopus 로고
    • A pilot trial of Saccharomyces boulardii in ulcerative colitis
    • Guslandi M. Giollo P. Testoni P.A. (2003) A pilot trial of Saccharomyces boulardii in ulcerative colitis. Eur J Gastroenterol Hepatol 15: 697–698.
    • (2003) Eur J Gastroenterol Hepatol , vol.15 , pp. 697-698
    • Guslandi, M.1    Giollo, P.2    Testoni, P.A.3
  • 69
    • 0033870413 scopus 로고    scopus 로고
    • Saccharomyces boulardii in maintenance treatment of Crohn's disease
    • Guslandi M. Mezzi G. Sorghi M. Testoni P.A. (2000) Saccharomyces boulardii in maintenance treatment of Crohn's disease. Dig Dis Sci 45: 1462–1464.
    • (2000) Dig Dis Sci , vol.45 , pp. 1462-1464
    • Guslandi, M.1    Mezzi, G.2    Sorghi, M.3    Testoni, P.A.4
  • 71
    • 1542315263 scopus 로고    scopus 로고
    • Effects of antibiotics and Saccharomyces boulardii on bacterial translocation in burn injury
    • Herek O. Kara I.G. Kaleli I. (2004) Effects of antibiotics and Saccharomyces boulardii on bacterial translocation in burn injury. Surg Today 34: 256–260.
    • (2004) Surg Today , vol.34 , pp. 256-260
    • Herek, O.1    Kara, I.G.2    Kaleli, I.3
  • 72
    • 0025270817 scopus 로고
    • Saccharomyces boulardii in acute adult diarrhea: efficacy and tolerability of treatment
    • Hochter W. Chase D. Hagenhoff G. (1990) Saccharomyces boulardii in acute adult diarrhea: efficacy and tolerability of treatment. Munch Med Wschr 132: 188–192.
    • (1990) Munch Med Wschr , vol.132 , pp. 188-192
    • Hochter, W.1    Chase, D.2    Hagenhoff, G.3
  • 73
    • 41249084682 scopus 로고    scopus 로고
    • Effect of Saccharomyces boulardii in the treatment of acute watery diarrhea in Myanmar children: a randomized controlled study
    • Htwe K. Yee K.S. Tin M. Vandenplas Y. (2008) Effect of Saccharomyces boulardii in the treatment of acute watery diarrhea in Myanmar children: a randomized controlled study. Am J Trop Med Hyg 78: 214–216.
    • (2008) Am J Trop Med Hyg , vol.78 , pp. 214-216
    • Htwe, K.1    Yee, K.S.2    Tin, M.3    Vandenplas, Y.4
  • 74
    • 57449099032 scopus 로고    scopus 로고
    • A randomized, open trial evaluating the effect of Saccharomyces boulardii on the eradication rate of Helicobacter pylori infection in children
    • Hurduc V. Plesca D. Dragomir D. Sajin M. Vandenplas Y. (2009) A randomized, open trial evaluating the effect of Saccharomyces boulardii on the eradication rate of Helicobacter pylori infection in children. Acta Paediatr 98: 127–131.
    • (2009) Acta Paediatr , vol.98 , pp. 127-131
    • Hurduc, V.1    Plesca, D.2    Dragomir, D.3    Sajin, M.4    Vandenplas, Y.5
  • 75
    • 67650400233 scopus 로고    scopus 로고
    • Probiotic gastrointestinal allergic reaction caused by Saccharomyces boulardii
    • Hwang J.B. Kang K.J. Kang Y.N. Kim A.S. (2009) Probiotic gastrointestinal allergic reaction caused by Saccharomyces boulardii. Ann Allergy Asthma Immunol 103: 87–88.
    • (2009) Ann Allergy Asthma Immunol , vol.103 , pp. 87-88
    • Hwang, J.B.1    Kang, K.J.2    Kang, Y.N.3    Kim, A.S.4
  • 76
    • 77957326669 scopus 로고    scopus 로고
    • [Recent advances in Saccharomyces boulardii research]
    • Suppl. 1
    • Im E. Pothoulakis C. (2010) [Recent advances in Saccharomyces boulardii research]. Gastroenterol Clin Biol 34(Suppl. 1): S62–S70.
    • (2010) Gastroenterol Clin Biol , vol.34 , pp. S62-S70
    • Im, E.1    Pothoulakis, C.2
  • 77
    • 0040699797 scopus 로고    scopus 로고
    • Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers
    • Jahn H.U. Ullrich R. Schneider T. Liehr R.M. Schieferdecker H.L. Holst H. et al. (1996) Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers. Digestion 57: 95–104.
    • (1996) Digestion , vol.57 , pp. 95-104
    • Jahn, H.U.1    Ullrich, R.2    Schneider, T.3    Liehr, R.M.4    Schieferdecker, H.L.5    Holst, H.6
  • 78
    • 36749082433 scopus 로고    scopus 로고
    • Clinical trial: multispecies probiotic supplementation alleviates the symptoms of irritable bowel syndrome and stabilizes intestinal microbiota
    • Kajander K. Myllyluoma E. Rajilic-Stojanovic M. Kyronpalo S. Rasmussen M. Jarvenpaa S. et al. (2008) Clinical trial: multispecies probiotic supplementation alleviates the symptoms of irritable bowel syndrome and stabilizes intestinal microbiota. Aliment Pharmacol Ther 27: 48–57.
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 48-57
    • Kajander, K.1    Myllyluoma, E.2    Rajilic-Stojanovic, M.3    Kyronpalo, S.4    Rasmussen, M.5    Jarvenpaa, S.6
  • 79
    • 0027367508 scopus 로고
    • Recovery and elimination of the biotherapeutic agent, Saccharomyces boulardii, in healthy human volunteers
    • Klein S.M. Elmer G.W. McFarland L.V. Surawicz C.M. Levy R.H. (1993) Recovery and elimination of the biotherapeutic agent, Saccharomyces boulardii, in healthy human volunteers. Pharm Res 10: 1615–1619.
    • (1993) Pharm Res , vol.10 , pp. 1615-1619
    • Klein, S.M.1    Elmer, G.W.2    McFarland, L.V.3    Surawicz, C.M.4    Levy, R.H.5
  • 80
    • 0027173742 scopus 로고
    • [Prevention of traveler's diarrhea with Saccharomyces boulardii. Results of a placebo controlled double-blind study]
    • Kollaritsch H. Holst H. Grobara P. Wiedermann G. (1993) [Prevention of traveler's diarrhea with Saccharomyces boulardii. Results of a placebo controlled double-blind study]. Fortschr Med 111: 152–156.
    • (1993) Fortschr Med , vol.111 , pp. 152-156
    • Kollaritsch, H.1    Holst, H.2    Grobara, P.3    Wiedermann, G.4
  • 81
    • 0001807647 scopus 로고
    • Prevention of traveller's diarrhea: comparison of different non-antibiotic preparations
    • Kollaritsch H. Kremsner P. Wiedermann G. Scheiner O. (1989) Prevention of traveller's diarrhea: comparison of different non-antibiotic preparations. Travel Med Internat 7: 9–18.
    • (1989) Travel Med Internat , vol.7 , pp. 9-18
    • Kollaritsch, H.1    Kremsner, P.2    Wiedermann, G.3    Scheiner, O.4
  • 82
    • 15044347921 scopus 로고    scopus 로고
    • Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea in children: a randomized double-blind placebo-controlled trial
    • Kotowska M. Albrecht P. Szajewska H. (2005) Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea in children: a randomized double-blind placebo-controlled trial. Aliment Pharmacol Ther 21: 583–590.
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 583-590
    • Kotowska, M.1    Albrecht, P.2    Szajewska, H.3
  • 83
    • 12344272168 scopus 로고    scopus 로고
    • Effects of Saccharomyces boulardii in children with acute diarrhoea
    • Kurugol Z. Koturoglu G. (2005) Effects of Saccharomyces boulardii in children with acute diarrhoea. Acta Paediatr 94: 44–47.
    • (2005) Acta Paediatr , vol.94 , pp. 44-47
    • Kurugol, Z.1    Koturoglu, G.2
  • 84
    • 0035915688 scopus 로고    scopus 로고
    • Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea
    • Kyne L. Warny M. Qamar A. Kelly C.P. (2001) Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea. Lancet 357: 189–193.
    • (2001) Lancet , vol.357 , pp. 189-193
    • Kyne, L.1    Warny, M.2    Qamar, A.3    Kelly, C.P.4
  • 85
    • 33747738231 scopus 로고    scopus 로고
    • [Saccharomyces boulardii activates expression of peroxisome proliferator-activated receptor-gamma in HT-29 cells]
    • Lee S.K. Kim H.J. Chi S.G. Jang J.Y. Nam K.D. Kim N.H. et al. (2005) [Saccharomyces boulardii activates expression of peroxisome proliferator-activated receptor-gamma in HT-29 cells]. Korean J Gastroenterol 45: 328–334.
    • (2005) Korean J Gastroenterol , vol.45 , pp. 328-334
    • Lee, S.K.1    Kim, H.J.2    Chi, S.G.3    Jang, J.Y.4    Nam, K.D.5    Kim, N.H.6
  • 86
    • 59449084229 scopus 로고    scopus 로고
    • The effect of Saccharomyces boulardii on human colon cells and inflammation in rats with trinitrobenzene sulfonic acid-induced colitis
    • Lee S.K. Kim Y.W. Chi S.G. Joo Y.S. Kim H.J. (2009) The effect of Saccharomyces boulardii on human colon cells and inflammation in rats with trinitrobenzene sulfonic acid-induced colitis. Dig Dis Sci 54: 255–263.
    • (2009) Dig Dis Sci , vol.54 , pp. 255-263
    • Lee, S.K.1    Kim, Y.W.2    Chi, S.G.3    Joo, Y.S.4    Kim, H.J.5
  • 88
    • 48249085783 scopus 로고    scopus 로고
    • Rapid determination of the bacterial composition of commercial probiotic products by terminal restriction fragment length polymorphism analysis
    • Marcobal A. Underwood M.A. Mills D.A. (2008) Rapid determination of the bacterial composition of commercial probiotic products by terminal restriction fragment length polymorphism analysis. J Pediatr Gastroenterol Nutr 46: 608–611.
    • (2008) J Pediatr Gastroenterol Nutr , vol.46 , pp. 608-611
    • Marcobal, A.1    Underwood, M.A.2    Mills, D.A.3
  • 89
    • 21244487834 scopus 로고    scopus 로고
    • Screening of yeasts as probiotic based on capacities to colonize the gastrointestinal tract and to protect against enteropathogen challenge in mice
    • Martins F.S. Nardi R.M. Arantes R.M. Rosa C.A. Neves M.J. Nicoli J.R. (2005) Screening of yeasts as probiotic based on capacities to colonize the gastrointestinal tract and to protect against enteropathogen challenge in mice. J Gen Appl Microbiol 51: 83–92.
    • (2005) J Gen Appl Microbiol , vol.51 , pp. 83-92
    • Martins, F.S.1    Nardi, R.M.2    Arantes, R.M.3    Rosa, C.A.4    Neves, M.J.5    Nicoli, J.R.6
  • 90
    • 70449469829 scopus 로고    scopus 로고
    • Effects of yeast probiotic formulation on viability, revival and protection against infection with Salmonella enterica ssp. enterica serovar Typhimurium in mice
    • Martins F.S. Veloso L.C. Arantes R.M. Nicoli J.R. (2009) Effects of yeast probiotic formulation on viability, revival and protection against infection with Salmonella enterica ssp. enterica serovar Typhimurium in mice. Lett Appl Microbiol 49: 738–744.
    • (2009) Lett Appl Microbiol , vol.49 , pp. 738-744
    • Martins, F.S.1    Veloso, L.C.2    Arantes, R.M.3    Nicoli, J.R.4
  • 91
    • 21244451548 scopus 로고    scopus 로고
    • Culture-dependent and culture-independent qualitative analysis of probiotic products claimed to contain bifidobacteria
    • Masco L. Huys G. de B.E. Temmerman R. Swings J. (2005) Culture-dependent and culture-independent qualitative analysis of probiotic products claimed to contain bifidobacteria. Int J Food Microbiol 102: 221–230.
    • (2005) Int J Food Microbiol , vol.102 , pp. 221-230
    • Masco, L.1    Huys, G.2    de, B.E.3    Temmerman, R.4    Swings, J.5
  • 92
    • 0020665293 scopus 로고
    • Treatment of irritable bowel syndrome with Saccharomyces boulardii: a double-blind, placebo-controlled study
    • Maupas J.L. Champemont P. Delforge M. (1983) Treatment of irritable bowel syndrome with Saccharomyces boulardii: a double-blind, placebo-controlled study. Med Chir Dig 12: 77–79.
    • (1983) Med Chir Dig , vol.12 , pp. 77-79
    • Maupas, J.L.1    Champemont, P.2    Delforge, M.3
  • 93
    • 33645455337 scopus 로고    scopus 로고
    • Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease
    • McFarland L.V. (2006) Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. Am J Gastroenterol 101: 812–822.
    • (2006) Am J Gastroenterol , vol.101 , pp. 812-822
    • McFarland, L.V.1
  • 94
    • 33846865120 scopus 로고    scopus 로고
    • Meta-analysis of probiotics for the prevention of traveler's diarrhea
    • McFarland L.V. (2007) Meta-analysis of probiotics for the prevention of traveler's diarrhea. Travel Med Infect Dis 5: 97–105.
    • (2007) Travel Med Infect Dis , vol.5 , pp. 97-105
    • McFarland, L.V.1
  • 95
    • 68949207025 scopus 로고    scopus 로고
    • Unraveling the causes of negative studies: a case of S boulardii for the prevention of antibiotic-associated diarrhea
    • McFarland L.V. (2009) Unraveling the causes of negative studies: a case of S boulardii for the prevention of antibiotic-associated diarrhea. Rev Med Chil 137: 719–720.
    • (2009) Rev Med Chil , vol.137 , pp. 719-720
    • McFarland, L.V.1
  • 96
    • 77952615260 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of Saccharomyces boulardii in adult patients
    • McFarland L.V. (2010) Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World J Gastroenterol 16: 2202–2222.
    • (2010) World J Gastroenterol , vol.16 , pp. 2202-2222
    • McFarland, L.V.1
  • 97
    • 49649088887 scopus 로고    scopus 로고
    • Meta-analysis of probiotics for the treatment of irritable bowel syndrome
    • McFarland L.V. Dublin S. (2008) Meta-analysis of probiotics for the treatment of irritable bowel syndrome. World J Gastroenterol 14: 2650–2661.
    • (2008) World J Gastroenterol , vol.14 , pp. 2650-2661
    • McFarland, L.V.1    Dublin, S.2
  • 98
    • 0028226085 scopus 로고
    • A randomized placebo-controlled trial of Saccharomyces boulardii in combination with standard antibiotics for Clostridium difficile disease
    • McFarland L.V. Surawicz C.M. Greenberg R.N. Fekety R. Elmer G.W. Moyer K.A. et al. (1994) A randomized placebo-controlled trial of Saccharomyces boulardii in combination with standard antibiotics for Clostridium difficile disease. JAMA 271: 1913–1918.
    • (1994) JAMA , vol.271 , pp. 1913-1918
    • McFarland, L.V.1    Surawicz, C.M.2    Greenberg, R.N.3    Fekety, R.4    Elmer, G.W.5    Moyer, K.A.6
  • 99
    • 41549123221 scopus 로고    scopus 로고
    • Saccharomyces boulardii interferes with Shigella pathogenesis by postinvasion signaling events
    • Mumy K.L. Chen X. Kelly C.P. McCormick B.A. (2008) Saccharomyces boulardii interferes with Shigella pathogenesis by postinvasion signaling events. Am J Physiol Gastrointest Liver Physiol 294: G599–G609.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294 , pp. G599-G609
    • Mumy, K.L.1    Chen, X.2    Kelly, C.P.3    McCormick, B.A.4
  • 100
    • 38149030021 scopus 로고    scopus 로고
    • Effective prophylaxis against rotavirus diarrhea using a combination of Lactobacillus rhamnosus GG and antibodies
    • Pant N. Marcotte H. Brussow H. Svensson L. Hammarstrom L. (2007) Effective prophylaxis against rotavirus diarrhea using a combination of Lactobacillus rhamnosus GG and antibodies. BMC Microbiol 7: 86.
    • (2007) BMC Microbiol , vol.7 , pp. 86
    • Pant, N.1    Marcotte, H.2    Brussow, H.3    Svensson, L.4    Hammarstrom, L.5
  • 101
    • 44949161833 scopus 로고    scopus 로고
    • Gastrointestinal microbiota in irritable bowel syndrome: their role in its pathogenesis and treatment
    • Parkes G.C. Brostoff J. Whelan K. Sanderson J.D. (2008) Gastrointestinal microbiota in irritable bowel syndrome: their role in its pathogenesis and treatment. Am J Gastroenterol 103: 1557–1567.
    • (2008) Am J Gastroenterol , vol.103 , pp. 1557-1567
    • Parkes, G.C.1    Brostoff, J.2    Whelan, K.3    Sanderson, J.D.4
  • 102
    • 0027502522 scopus 로고
    • Therapeutic effects of Saccharomyces boulardii on mild residual symptoms in a stable phase of Crohn's disease with special respect to chronic diarrhea–a pilot study
    • Plein K. Hotz J. (1993) Therapeutic effects of Saccharomyces boulardii on mild residual symptoms in a stable phase of Crohn's disease with special respect to chronic diarrhea–a pilot study. Z Gastroenterol 31: 129–134.
    • (1993) Z Gastroenterol , vol.31 , pp. 129-134
    • Plein, K.1    Hotz, J.2
  • 103
    • 70349213718 scopus 로고    scopus 로고
    • Review article: anti-inflammatory mechanisms of action of Saccharomyces boulardii
    • Pothoulakis C. (2009) Review article: anti-inflammatory mechanisms of action of Saccharomyces boulardii. Aliment Pharmacol Ther 30: 826–833.
    • (2009) Aliment Pharmacol Ther , vol.30 , pp. 826-833
    • Pothoulakis, C.1
  • 104
    • 0027516691 scopus 로고
    • Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum
    • Pothoulakis C. Kelly C.P. Joshi M.A. Gao N. O'Keane C.J. Castagliuolo I. et al. (1993) Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum. Gastroenterology 104: 1108–1115.
    • (1993) Gastroenterology , vol.104 , pp. 1108-1115
    • Pothoulakis, C.1    Kelly, C.P.2    Joshi, M.A.3    Gao, N.4    O'Keane, C.J.5    Castagliuolo, I.6
  • 105
    • 0035077712 scopus 로고    scopus 로고
    • Saccharomyces boulardii stimulates intestinal immunoglobulin A immune response to Clostridium difficile toxin A in mice
    • Qamar A. Aboudola S. Warny M. Michetti P. Pothoulakis C. La Mont J.T. et al. (2001) Saccharomyces boulardii stimulates intestinal immunoglobulin A immune response to Clostridium difficile toxin A in mice. Infect Immun 69: 2762–2765.
    • (2001) Infect Immun , vol.69 , pp. 2762-2765
    • Qamar, A.1    Aboudola, S.2    Warny, M.3    Michetti, P.4    Pothoulakis, C.5    La Mont, J.T.6
  • 106
    • 0028197635 scopus 로고
    • Inhibitory activity of saccharomyces yeasts on the adhesion of Entamoeba histolytica trophozoites to human erythrocytes in vitro
    • Rigothier M.C. Maccario J. Gayral P. (1994) Inhibitory activity of saccharomyces yeasts on the adhesion of Entamoeba histolytica trophozoites to human erythrocytes in vitro. Parasitol Res 80: 10–15.
    • (1994) Parasitol Res , vol.80 , pp. 10-15
    • Rigothier, M.C.1    Maccario, J.2    Gayral, P.3
  • 107
    • 0033833633 scopus 로고    scopus 로고
    • Saccharomyces boulardii stimulates sIgA production and the phagocytic system of gnotobiotic mice
    • Rodrigues A.C. Cara D.C. Fretez S.H. Cunha F.Q. Vieira E.C. Nicoli J.R. et al. (2000) Saccharomyces boulardii stimulates sIgA production and the phagocytic system of gnotobiotic mice. J Appl Microbiol 89: 404–414.
    • (2000) J Appl Microbiol , vol.89 , pp. 404-414
    • Rodrigues, A.C.1    Cara, D.C.2    Fretez, S.H.3    Cunha, F.Q.4    Vieira, E.C.5    Nicoli, J.R.6
  • 108
    • 0029797776 scopus 로고    scopus 로고
    • Effect of Saccharomyces boulardii against experimental oral infection with Salmonella typhimurium and Shigella flexneri in conventional and gnotobiotic mice
    • Rodrigues A.C. Nardi R.M. Bambirra E.A. Vieira E.C. Nicoli J.R. (1996) Effect of Saccharomyces boulardii against experimental oral infection with Salmonella typhimurium and Shigella flexneri in conventional and gnotobiotic mice. J Appl Bacteriol 81: 251–256.
    • (1996) J Appl Bacteriol , vol.81 , pp. 251-256
    • Rodrigues, A.C.1    Nardi, R.M.2    Bambirra, E.A.3    Vieira, E.C.4    Nicoli, J.R.5
  • 109
    • 0025798346 scopus 로고
    • [Efficacy of Saccharomyces boulardii in the treatment of diarrhea in AIDS]
    • Saint-Marc T. Rossello-Prats L. Touraine J.L. (1991) [Efficacy of Saccharomyces boulardii in the treatment of diarrhea in AIDS]. Ann Med Interne (Paris) 142: 64–65.
    • (1991) Ann Med Interne (Paris) , vol.142 , pp. 64-65
    • Saint-Marc, T.1    Rossello-Prats, L.2    Touraine, J.L.3
  • 110
    • 0003019422 scopus 로고
    • Value of Saccharomyces boulardii in the digestive acceptability of continuous-flow enteral nutrition in burnt patients
    • Schlotterer M. Bernasconi P. Le Breton F. Wassermann D. (1987) Value of Saccharomyces boulardii in the digestive acceptability of continuous-flow enteral nutrition in burnt patients. Nutr Clin Metabol 1: 31–34.
    • (1987) Nutr Clin Metabol , vol.1 , pp. 31-34
    • Schlotterer, M.1    Bernasconi, P.2    Le Breton, F.3    Wassermann, D.4
  • 111
    • 30644475117 scopus 로고    scopus 로고
    • Effects of Saccharomyces boulardii on fecal short-chain fatty acids and microflora in patients on long-term total enteral nutrition
    • Schneider S.M. Girard-Pipau F. Filippi J. Hebuterne X. Moyse D. Hinojosa G.C. et al. (2005) Effects of Saccharomyces boulardii on fecal short-chain fatty acids and microflora in patients on long-term total enteral nutrition. World J Gastroenterol 11: 6165–6169.
    • (2005) World J Gastroenterol , vol.11 , pp. 6165-6169
    • Schneider, S.M.1    Girard-Pipau, F.2    Filippi, J.3    Hebuterne, X.4    Moyse, D.5    Hinojosa, G.C.6
  • 113
    • 77952653193 scopus 로고    scopus 로고
    • The effect of Saccharomyces boulardii on reducing irinotecan-induced intestinal mucositis and diarrhea
    • Sezer A. Usta U. Cicin I. (2009) The effect of Saccharomyces boulardii on reducing irinotecan-induced intestinal mucositis and diarrhea. Med Oncol 26: 350–357.
    • (2009) Med Oncol , vol.26 , pp. 350-357
    • Sezer, A.1    Usta, U.2    Cicin, I.3
  • 114
    • 33645104228 scopus 로고    scopus 로고
    • Saccharomyces boulardii produces a soluble anti-inflammatory factor that inhibits NF-kappa B-mediated IL-8 gene expression
    • Sougioultzis S. Simeonidis S. Bhaskar K.R. Chen X. Anton P.M. Keates S. et al. (2006) Saccharomyces boulardii produces a soluble anti-inflammatory factor that inhibits NF-kappa B-mediated IL-8 gene expression. Biochem Biophys Res Commun 343: 69–76.
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 69-76
    • Sougioultzis, S.1    Simeonidis, S.2    Bhaskar, K.R.3    Chen, X.4    Anton, P.M.5    Keates, S.6
  • 115
    • 0034450738 scopus 로고    scopus 로고
    • The search for a better treatment for recurrent Clostridium difficile disease: use of high-dose vancomycin combined with Saccharomyces boulardii
    • Surawicz C.M. McFarland L.V. Greenberg R.N. Rubin M. Fekety R. Mulligan M.E. et al. (2000) The search for a better treatment for recurrent Clostridium difficile disease: use of high-dose vancomycin combined with Saccharomyces boulardii. Clin Infect Dis 31: 1012–1017.
    • (2000) Clin Infect Dis , vol.31 , pp. 1012-1017
    • Surawicz, C.M.1    McFarland, L.V.2    Greenberg, R.N.3    Rubin, M.4    Fekety, R.5    Mulligan, M.E.6
  • 116
    • 48549097837 scopus 로고    scopus 로고
    • Biostructure of fecal microbiota in healthy subjects and patients with chronic idiopathic diarrhea
    • Swidsinski A. Loening-Baucke V. Verstraelen H. Osowska S. Doerffel Y. (2008) Biostructure of fecal microbiota in healthy subjects and patients with chronic idiopathic diarrhea. Gastroenterology 135: 568–579.
    • (2008) Gastroenterology , vol.135 , pp. 568-579
    • Swidsinski, A.1    Loening-Baucke, V.2    Verstraelen, H.3    Osowska, S.4    Doerffel, Y.5
  • 117
    • 78449305654 scopus 로고    scopus 로고
    • Meta-analysis: the effects of Saccharomyces boulardii supplementation on Helicobacter pylori eradication rates and side effects during treatment
    • Szajewska H. Horvath A. Piwowarczyk A. (2010) Meta-analysis: the effects of Saccharomyces boulardii supplementation on Helicobacter pylori eradication rates and side effects during treatment. Aliment Pharmacol Ther 32: 1069–1079.
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 1069-1079
    • Szajewska, H.1    Horvath, A.2    Piwowarczyk, A.3
  • 118
    • 24344493550 scopus 로고    scopus 로고
    • Meta-analysis: non-pathogenic yeast Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea
    • Szajewska H. Mrukowicz J. (2005) Meta-analysis: non-pathogenic yeast Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea. Aliment Pharmacol Ther 22: 365–372.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 365-372
    • Szajewska, H.1    Mrukowicz, J.2
  • 119
    • 33744462850 scopus 로고    scopus 로고
    • Probiotics in gastrointestinal diseases in children: hard and not-so-hard evidence of efficacy
    • Szajewska H. Setty M. Mrukowicz J. Guandalini S. (2006) Probiotics in gastrointestinal diseases in children: hard and not-so-hard evidence of efficacy. J Pediatr Gastroenterol Nutr 42: 454–475.
    • (2006) J Pediatr Gastroenterol Nutr , vol.42 , pp. 454-475
    • Szajewska, H.1    Setty, M.2    Mrukowicz, J.3    Guandalini, S.4
  • 120
    • 70349678942 scopus 로고    scopus 로고
    • Saccharomyces boulardii for treating acute gastroenteritis in children: updated meta-analysis of randomized controlled trials
    • Szajewska H. Skorka A. (2009) Saccharomyces boulardii for treating acute gastroenteritis in children: updated meta-analysis of randomized controlled trials. Aliment Pharmacol Ther 30: 960–961.
    • (2009) Aliment Pharmacol Ther , vol.30 , pp. 960-961
    • Szajewska, H.1    Skorka, A.2
  • 121
    • 33846287913 scopus 로고    scopus 로고
    • Meta-analysis: Saccharomyces boulardii for treating acute diarrhoea in children
    • Szajewska H. Skorka A. Dylag M. (2007) Meta-analysis: Saccharomyces boulardii for treating acute diarrhoea in children. Aliment Pharmacol Ther 25: 257–264.
    • (2007) Aliment Pharmacol Ther , vol.25 , pp. 257-264
    • Szajewska, H.1    Skorka, A.2    Dylag, M.3
  • 122
    • 0036300891 scopus 로고    scopus 로고
    • Inhibition of in vitro cell adherence of Clostridium difficile by Saccharomyces boulardii
    • Tasteyre A. Barc M.C. Karjalainen T. Bourlioux P. Collignon A. (2002) Inhibition of in vitro cell adherence of Clostridium difficile by Saccharomyces boulardii. Microb Pathog 32: 219–225.
    • (2002) Microb Pathog , vol.32 , pp. 219-225
    • Tasteyre, A.1    Barc, M.C.2    Karjalainen, T.3    Bourlioux, P.4    Collignon, A.5
  • 123
    • 0020532820 scopus 로고
    • [Prevention of diarrhea administering Saccharomyces boulardii during continuous enteral feeding]
    • Tempe J.D. Steidel A.L. Blehaut H. Hasselmann M. Lutun P. Maurier F. (1983) [Prevention of diarrhea administering Saccharomyces boulardii during continuous enteral feeding]. Sem Hop 59: 1409–1412.
    • (1983) Sem Hop , vol.59 , pp. 1409-1412
    • Tempe, J.D.1    Steidel, A.L.2    Blehaut, H.3    Hasselmann, M.4    Lutun, P.5    Maurier, F.6
  • 124
    • 61849185743 scopus 로고    scopus 로고
    • Saccharomyces boulardii inhibits lipopolysaccharide-induced activation of human dendritic cells and T cell proliferation
    • Thomas S. Przesdzing I. Metzke D. Schmitz J. Radbruch A. Baumgart D.C. (2009) Saccharomyces boulardii inhibits lipopolysaccharide-induced activation of human dendritic cells and T cell proliferation. Clin Exp Immunol 156: 78–87.
    • (2009) Clin Exp Immunol , vol.156 , pp. 78-87
    • Thomas, S.1    Przesdzing, I.2    Metzke, D.3    Schmitz, J.4    Radbruch, A.5    Baumgart, D.C.6
  • 125
    • 33846012178 scopus 로고    scopus 로고
    • Meta-analysis: the effect of supplementation with probiotics on eradication rates and adverse events during Helicobacter pylori eradication therapy
    • Tong J.L. Ran Z.H. Shen J. Zhang C.X. Xiao S.D. (2007) Meta-analysis: the effect of supplementation with probiotics on eradication rates and adverse events during Helicobacter pylori eradication therapy. Aliment Pharmacol Ther 25: 155–168.
    • (2007) Aliment Pharmacol Ther , vol.25 , pp. 155-168
    • Tong, J.L.1    Ran, Z.H.2    Shen, J.3    Zhang, C.X.4    Xiao, S.D.5
  • 126
    • 0021142921 scopus 로고
    • Prevention of clindamycin-induced mortality in hamsters by Saccharomyces boulardii
    • Toothaker R.D. Elmer G.W. (1984) Prevention of clindamycin-induced mortality in hamsters by Saccharomyces boulardii. Antimicrob Agents Chemother 26: 552–556.
    • (1984) Antimicrob Agents Chemother , vol.26 , pp. 552-556
    • Toothaker, R.D.1    Elmer, G.W.2
  • 129
    • 0022592266 scopus 로고
    • [Influence of Saccharomyces boulardii on jejunal secretion in rats induced by cholera toxin]
    • Vidon N. Huchet B. Rambaud J.C. (1986) [Influence of Saccharomyces boulardii on jejunal secretion in rats induced by cholera toxin]. Gastroenterol Clin Biol 10: 13–16.
    • (1986) Gastroenterol Clin Biol , vol.10 , pp. 13-16
    • Vidon, N.1    Huchet, B.2    Rambaud, J.C.3
  • 130
    • 33947543759 scopus 로고    scopus 로고
    • Saccharomyces boulardii in acute childhood diarrhoea: a randomized, placebo-controlled study
    • Villarruel G. Rubio D.M. Lopez F. Cintioni J. Gurevech R. Romero G. et al. (2007) Saccharomyces boulardii in acute childhood diarrhoea: a randomized, placebo-controlled study. Acta Paediatr 96: 538–541.
    • (2007) Acta Paediatr , vol.96 , pp. 538-541
    • Villarruel, G.1    Rubio, D.M.2    Lopez, F.3    Cintioni, J.4    Gurevech, R.5    Romero, G.6
  • 131
    • 0346496214 scopus 로고    scopus 로고
    • Evaluation of deficiencies in labeling of commercial probiotics
    • Weese J.S. (2003) Evaluation of deficiencies in labeling of commercial probiotics. Can Vet J 44: 982–983.
    • (2003) Can Vet J , vol.44 , pp. 982-983
    • Weese, J.S.1
  • 132
    • 77749254707 scopus 로고    scopus 로고
    • Safety of probiotics in patients receiving nutritional support: a systematic review of case reports, randomized controlled trials, and nonrandomized trials
    • Whelan K. Myers C.E. (2010) Safety of probiotics in patients receiving nutritional support: a systematic review of case reports, randomized controlled trials, and nonrandomized trials. Am J Clin Nutr 91: 687–703.
    • (2010) Am J Clin Nutr , vol.91 , pp. 687-703
    • Whelan, K.1    Myers, C.E.2
  • 133
    • 38349092363 scopus 로고    scopus 로고
    • Saccharomyces boulardii ameliorates Citrobacter rodentium- induced colitis through actions on bacterial virulence factors
    • Wu X. Vallance B.A. Boyer L. Bergstrom K.S. Walker J. Madsen K. et al. (2008) Saccharomyces boulardii ameliorates Citrobacter rodentium- induced colitis through actions on bacterial virulence factors. Am J Physiol Gastrointest Liver Physiol 294: G295-G306.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294 , pp. G295-G306
    • Wu, X.1    Vallance, B.A.2    Boyer, L.3    Bergstrom, K.S.4    Walker, J.5    Madsen, K.6
  • 134
    • 54849423926 scopus 로고    scopus 로고
    • Saccharomyces boulardii effects on gastrointestinal diseases
    • Zanello G. Meurens F. Berri M. Salmon H. (2009) Saccharomyces boulardii effects on gastrointestinal diseases. Curr Issues Mol Biol 11: 47–58.
    • (2009) Curr Issues Mol Biol , vol.11 , pp. 47-58
    • Zanello, G.1    Meurens, F.2    Berri, M.3    Salmon, H.4


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