Saccharomyces boulardii inhibits ERK1/2 mitogen-activated protein kinase activation both in vitro and in vivo and protects against Clostridium difficile toxin A-induced enteritis

Journal of Biological Chemistry

Volumn 281, Issue 34, 2006, Pages 24449-24454

  Chen, Xinhua ^a,c   Kokkotou, Efi G ^a   Mustafa, Nasima ^a   Bhaskar, K Ramakrishnan ^a   Sougioultzis, Stavros ^a   O'Brien, Michael ^b   Pothoulakis, Charalabos ^a   Kelly, Ciarán P ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DISEASES; ENZYME INHIBITION; HISTOLOGY; TOXIC MATERIALS;

GASTROINTESTINAL DISORDERS; PATHOGENS; PROTEIN KINASE; SACCHAROMYCES BOULARDII;

YEAST;

CLOSTRIDIUM DIFFICILE TOXIN A; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; ENTERITIS; GASTROINTESTINAL DISEASE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; ILEUM MUCOSA; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTESTINE INJURY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SACCHAROMYCES BOULARDII; TISSUE INJURY;

ANIMALS; BACTERIAL TOXINS; CELL LINE; ENTERITIS; ENTEROTOXINS; HUMANS; INTESTINAL MUCOSA; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROBIOTICS; RATS; SACCHAROMYCES;

CLOSTRIDIUM DIFFICILE; SACCHAROMYCES BOULARDII;

EID: 33747699728     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M605200200     Document Type: Article

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