Saccharomyces boulardii improves intestinal cell restitution through activation of the α2β1 integrin collagen receptor

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Canonici, Alexandra ^a,b   Siret, Carole ^a,b   Pellegrino, Emilie ^a,b   Pontier Bres, Rodolphe ^c   Pouyet, Laurent ^d   Montero, Marie Pierre ^a,b   Colin, Carole ^a,b   Czerucka, Dorota ^c   Rigot, Véronique ^a,b   André, Frédéric ^a,b  

^a University of the Mediterranean Aix Marseille II   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2BETA1 INTEGRIN COLLAGEN RECEPTOR; COLLAGEN RECEPTOR; FOCAL ADHESION KINASE; MICROBIAL PRODUCTS NOT CLASSIFIED ELSEWHERE; PAXILLIN; TYROSINE; UNCLASSIFIED DRUG; PROBIOTIC AGENT; VERY LATE ACTIVATION ANTIGEN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL ADHESION; CELL ASSAY; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; DRUG MECHANISM; DRUG SCREENING; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CELL; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SACCHAROMYCES BOULARDII; SIGNAL TRANSDUCTION; SUPERNATANT; WOUND HEALING; ANIMAL; CELL MOTION; CELL STRAIN CACO 2; CELL STRAIN HT29; CYTOLOGY; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; METABOLISM; SACCHAROMYCES;

MUS; SACCHAROMYCES BOULARDII;

ANIMALS; CACO-2 CELLS; CELL ADHESION; CELL MOVEMENT; ENTEROCYTES; FEMALE; HT29 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INTEGRIN ALPHA2BETA1; MICE; PROBIOTICS; RECEPTORS, COLLAGEN; SACCHAROMYCES;

EID: 79953661081     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018427     Document Type: Article

References (41)

1. Blikslager AT, Moeser AJ, Gookin JL, Jones SL, Odle J, (2007) Restoration of barrier function in injured intestinal mucosa. Physiol Rev 87: 545-564.
2. Sturm A, Dignass AU, (2008) Epithelial restitution and wound healing in inflammatory bowel disease. World J Gastroenterol 14: 348-353.
3. Mumy KL, Chen X, Kelly CP, McCormick BA, (2008) Saccharomyces boulardii interferes with Shigella pathogenesis by postinvasion signaling events. Am J Physiol Gastrointest Liver Physiol 294: G599-609.
4. Martins FS, Veloso LC, Arantes RM, Nicoli JR, (2009) Effects of yeast probiotic formulation on viability, revival and protection against infection with Salmonella enterica ssp. enterica serovar Typhimurium in mice. Lett Appl Microbiol 49: 738-744.
5. Goke M, Kanai M, Lynch-Devaney K, Podolsky DK, (1998) Rapid mitogen-activated protein kinase activation by transforming growth factor alpha in wounded rat intestinal epithelial cells. Gastroenterology 114: 697-705.
6. Basson MD, (2001) In vitro evidence for matrix regulation of intestinal epithelial biology during mucosal healing. Life Sci 69: 3005-3018.
7. Zhang J, Owen CR, Sanders MA, Turner JR, Basson MD, (2006) The motogenic effects of cyclic mechanical strain on intestinal epithelial monolayer wound closure are matrix dependent. Gastroenterology 131: 1179-1189.
8. Gilcrease MZ, (2007) Integrin signaling in epithelial cells. Cancer Lett 247: 1-25.
9. Czerucka D, Piche T, Rampal P, (2007) Review article: yeast as probiotics - Saccharomyces boulardii. Aliment Pharmacol Ther 26: 767-778.
10. Pothoulakis C, (2009) Review article: anti-inflammatory mechanisms of action of Saccharomyces boulardii. Aliment Pharmacol Ther 30: 826-833.
11. Buts JP, De Keyser N, (2010) Transduction pathways regulating the trophic effects of Saccharomyces boulardii in rat intestinal mucosa. Scand J Gastroenterol 45: 175-185.
12. Plein K, Hotz J, (1993) Therapeutic effects of Saccharomyces boulardii on mild residual symptoms in a stable phase of Crohn's disease with special respect to chronic diarrhea-a pilot study. Z Gastroenterol 31: 129-134.
13. Guslandi M, Mezzi G, Sorghi M, Testoni PA, (2000) Saccharomyces boulardii in maintenance treatment of Crohn's disease. Dig Dis Sci 45: 1462-1464.
14. Girard P, Pansart Y, Coppe MC, Gillardin JM, (2005) Saccharomyces boulardii inhibits water and electrolytes changes induced by castor oil in the rat colon. Dig Dis Sci 50: 2183-2190.
15. Dalmasso G, Cottrez F, Imbert V, Lagadec P, Peyron JF, et al. (2006) Saccharomyces boulardii inhibits inflammatory bowel disease by trapping T cells in mesenteric lymph nodes. Gastroenterology 131: 1812-1825.
16. Dalmasso G, Loubat A, Dahan S, Calle G, Rampal P, et al. (2006) Saccharomyces boulardii prevents TNF-alpha-induced apoptosis in EHEC-infected T84 cells. Res Microbiol 157: 456-465.
17. Vermeulen SJ, Bruyneel EA, Bracke ME, De Bruyne GK, Vennekens KM, et al. (1995) Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells. Cancer Res 55: 4722-4728.
18. Chantret I, Rodolosse A, Barbat A, Dussaulx E, Brot-Laroche E, et al. (1994) Differential expression of sucrase-isomaltase in clones isolated from early and late passages of the cell line Caco-2: evidence for glucose-dependent negative regulation. J Cell Sci 107 (Pt 1): 213-225.
19. Fantini J, Abadie B, Tirard A, Remy L, Ripert JP, et al. (1986) Spontaneous and induced dome formation by two clonal cell populations derived from a human adenocarcinoma cell line, HT29. J Cell Sci 83: 235-249.
20. Dharmsathaphorn K, McRoberts JA, Mandel KG, Tisdale LD, Masui H, (1984) A human colonic tumor cell line that maintains vectorial electrolyte transport. Am J Physiol 246: G204-208.
21. Chen X, Kokkotou EG, Mustafa N, Bhaskar KR, Sougioultzis S, et al. (2006) Saccharomyces boulardii inhibits ERK1/2 mitogen-activated protein kinase activation both in vitro and in vivo and protects against Clostridium difficile toxin A-induced enteritis. J Biol Chem 281: 24449-24454.
22. Rigot V, Lehmann M, Andre F, Daemi N, Marvaldi J, et al. (1998) Integrin ligation and PKC activation are required for migration of colon carcinoma cells. J Cell Sci 111 (Pt 20): 3119-3127.
23. Canonici A, Steelant W, Rigot V, Khomitch-Baud A, Boutaghou-Cherid H, et al. (2008) Insulin-like growth factor-I receptor, E-cadherin and alpha v integrin form a dynamic complex under the control of alpha-catenin. Int J Cancer 122: 572-582.
24. Andre F, Rigot V, Remacle-Bonnet M, Luis J, Pommier G, et al. (1999) Protein kinases C-gamma and-delta are involved in insulin-like growth factor I-induced migration of colonic epithelial cells. Gastroenterology 116: 64-77.
25. Andre F, Janssens B, Bruyneel E, van Roy F, Gespach C, et al. (2004) Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells. Oncogene 23: 1177-1186.
26. Qureshi FG, Leaphart C, Cetin S, Li J, Grishin A, et al. (2005) Increased expression and function of integrins in enterocytes by endotoxin impairs epithelial restitution. Gastroenterology 128: 1012-1022.
27. Wilson AJ, Gibson PR, (1997) Epithelial migration in the colon: filling in the gaps. Clin Sci (Lond) 93: 97-108.
28. Arroyo AG, Garcia-Pardo A, Sanchez-Madrid F, (1993) A high affinity conformational state on VLA integrin heterodimers induced by an anti-beta 1 chain monoclonal antibody. J Biol Chem 268: 9863-9868.
29. Sinha A, Nightingale J, West KP, Berlanga-Acosta J, Playford RJ, (2003) Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis. N Engl J Med 349: 350-357.
30. Zeeh JM, Procaccino F, Hoffmann P, Aukerman SL, McRoberts JA, et al. (1996) Keratinocyte growth factor ameliorates mucosal injury in an experimental model of colitis in rats. Gastroenterology 110: 1077-1083.
31. Ido A, Numata M, Kodama M, Tsubouchi H, (2005) Mucosal repair and growth factors: recombinant human hepatocyte growth factor as an innovative therapy for inflammatory bowel disease. J Gastroenterol 40: 925-931.
32. Manske M, Bade EG, (1994) Growth factor-induced cell migration: biology and methods of analysis. Int Rev Cytol 155: 49-96.
33. Brasken P, Lehto M, Renvall S, (1990) Fibronectin, laminin, and collagen types I, III, IV and V in the healing rat colon anastomosis. Ann Chir Gynaecol 79: 65-71.
34. Andre F, Rigot V, Thimonier J, Montixi C, Parat F, et al. (1999) Integrins and E-cadherin cooperate with IGF-I to induce migration of epithelial colonic cells. Int J Cancer 83: 497-505.
35. Grzesiak JJ, Bouvet M, (2008) Activation of the alpha2beta1 integrin-mediated malignant phenotype on type I collagen in pancreatic cancer cells by shifts in the concentrations of extracellular Mg2+ and Ca2+. Int J Cancer 122: 2199-2209.
36. Humphries MJ, (1996) Integrin activation: the link between ligand binding and signal transduction. Curr Opin Cell Biol 8: 632-640.
37. Zaidel-Bar R, Itzkovitz S, Ma'ayan A, Iyengar R, Geiger B, (2007) Functional atlas of the integrin adhesome. Nat Cell Biol 9: 858-867.
38. Buts JP, (2009) Twenty-five years of research on Saccharomyces boulardii trophic effects: updates and perspectives. Dig Dis Sci 54: 15-18.
39. Zanello G, Meurens F, Berri M, Salmon H, (2009) Saccharomyces boulardii effects on gastrointestinal diseases. Curr Issues Mol Biol 11: 47-58.
40. Sougioultzis S, Simeonidis S, Bhaskar KR, Chen X, Anton PM, et al. (2006) Saccharomyces boulardii produces a soluble anti-inflammatory factor that inhibits NF-kappaB-mediated IL-8 gene expression. Biochem Biophys Res Commun 343: 69-76.
41. Lee SK, Kim HJ, Chi SG, Jang JY, Nam KD, et al. (2005) [Saccharomyces boulardii activates expression of peroxisome proliferator-activated receptor-gamma in HT-29 cells]. Korean J Gastroenterol 45: 328-334.