-
1
-
-
0025945901
-
Internal initiation of translation in retroviral vectors carrying picornavirus 5′ nontranslated regions
-
M.A. Adam, N. Ramesh, A.D. Miller, and W.R. Osborne Internal initiation of translation in retroviral vectors carrying picornavirus 5′ nontranslated regions J. Virol. 65 1991 4985 4990
-
(1991)
J. Virol.
, vol.65
, pp. 4985-4990
-
-
Adam, M.A.1
Ramesh, N.2
Miller, A.D.3
Osborne, W.R.4
-
2
-
-
0033999084
-
Gene silencing as a threat to the success of gene therapy
-
T.H. Bestor Gene silencing as a threat to the success of gene therapy J. Clin. Invest. 105 2000 409 411 (Pubitemid 30127239)
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.4
, pp. 409-411
-
-
Bestor, T.H.1
-
3
-
-
0030783593
-
Enhanced green fluorescent protein as selectable marker of retroviral- mediated gene transfer in immature hematopoietic bone marrow cells
-
M.F. Bierhuizen, Y. Westerman, T.P. Visser, W. Dimjati, A.W. Wognum, and G. Wagemaker Enhanced green fluorescent protein as selectable marker of retroviral-mediated gene transfer in immature hematopoietic bone marrow cells Blood 90 1997 3304 3315 (Pubitemid 27473398)
-
(1997)
Blood
, vol.90
, Issue.9
, pp. 3304-3315
-
-
Bierhuizen, M.F.A.1
Westerman, Y.2
Visser, T.P.3
Dimjati, W.4
Wognum, A.W.5
Wagemaker, G.6
-
4
-
-
0037424875
-
Current developments in the design of onco-retrovirus and lentivirus vector systems for hematopoietic cell gene therapy
-
DOI 10.1016/S0167-4889(03)00024-7
-
S. Brenner, and H.L. Malech Current developments in the design of onco-retrovirus and lentivirus vector systems for hematopoietic cell gene therapy Biochim. Biophys. Acta 1640 2003 1 24 (Pubitemid 36369633)
-
(2003)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1640
, Issue.1
, pp. 1-24
-
-
Brenner, S.1
Malech, H.L.2
-
5
-
-
0141889328
-
+ cells
-
DOI 10.1182/blood-2002-05-1482
-
+ cells Blood 102 2003 2789 2797 (Pubitemid 37248848)
-
(2003)
Blood
, vol.102
, Issue.8
, pp. 2789-2797
-
-
Brenner, S.1
Whiting-Theobald, N.L.2
Linton, G.F.3
Holmes, K.L.4
Anderson-Cohen, M.5
Kelly, P.F.6
Vanin, E.F.7
Pilon, A.M.8
Bodine, D.M.9
Horwitz, M.E.10
Malech, H.L.11
-
6
-
-
67651087321
-
Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications
-
B.D. Brown, and L. Naldini Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications Nat. Rev. Genet. 10 2009 578 585
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 578-585
-
-
Brown, B.D.1
Naldini, L.2
-
7
-
-
0027376309
-
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
-
DOI 10.1038/365666a0
-
M.I. Bukrinsky, S. Haggerty, M.P. Dempsey, N. Sharova, A. Adzhubel, L. Spitz, P. Lewis, D. Goldfarb, M. Emerman, and M. Stevenson A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells Nature 365 1993 666 669 (Pubitemid 23350541)
-
(1993)
Nature
, vol.365
, Issue.6447
, pp. 666-669
-
-
Bukrinsky, M.I.1
Haggerty, S.2
Dempsey, M.P.3
Sharova, N.4
Adzhubei, A.5
Spitz, L.6
Lewis, P.7
Goldfarb, D.8
Emerman, M.9
Stevenson, M.10
-
8
-
-
13044309472
-
- human hematopoietic cells by HIV-1-based lentiviral vectors
-
DOI 10.1073/pnas.96.6.2988
-
S.S. Case, M.A. Price, C.T. Jordan, X.J. Yu, L. Wang, G. Bauer, D.L. Haas, D. Xu, R. Stripecke, L. Naldini, D.B. Kohn, and G.M. Crooks Stable transduction of quiescent CD34(+)CD38(-) human hematopoietic cells by HIV-1-based lentiviral vectors Proc. Natl. Acad. Sci. USA 96 1999 2988 2993 (Pubitemid 29148831)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.6
, pp. 2988-2993
-
-
Case, S.S.1
Price, M.A.2
Jordan, C.T.3
Yu, X.J.4
Wang, L.5
Bauer, G.6
Haas, D.L.7
Xu, D.8
Stripecke, R.9
Naldini, L.10
Kohn, D.B.11
Crooks, G.M.12
-
9
-
-
33847178027
-
Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients
-
S. Charrier, L. Dupre, S. Scaramuzza, L. Jeanson-Leh, M.P. Blundell, O. Danos, F. Cattaneo, A. Aiuti, R. Eckenberg, A.J. Thrasher, M.G. Roncarolo, and A. Galy Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients Gene Ther. 14 2007 415 428
-
(2007)
Gene Ther.
, vol.14
, pp. 415-428
-
-
Charrier, S.1
Dupre, L.2
Scaramuzza, S.3
Jeanson-Leh, L.4
Blundell, M.P.5
Danos, O.6
Cattaneo, F.7
Aiuti, A.8
Eckenberg, R.9
Thrasher, A.J.10
Roncarolo, M.G.11
Galy, A.12
-
10
-
-
0028839609
-
High-titer packaging cells producing recombinant retroviruses resistant to human serum
-
F.L. Cosset, Y. Takeuchi, J.L. Battini, R.A. Weiss, and M.K. Collins High-titer packaging cells producing recombinant retroviruses resistant to human serum J. Virol. 69 1995 7430 7436
-
(1995)
J. Virol.
, vol.69
, pp. 7430-7436
-
-
Cosset, F.L.1
Takeuchi, Y.2
Battini, J.L.3
Weiss, R.A.4
Collins, M.K.5
-
11
-
-
0035798131
-
Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr
-
DOI 10.1126/science.1063957
-
C.M. de Noronha, M.P. Sherman, H.W. Lin, M.V. Cavrois, R.D. Moir, R.D. Goldman, and W.C. Greene Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr Science 294 2001 1105 1108 (Pubitemid 33041866)
-
(2001)
Science
, vol.294
, Issue.5544
, pp. 1105-1108
-
-
De Noronha, C.M.C.1
Sherman, M.P.2
Lin, H.W.3
Cavrois, M.V.4
Moir, R.D.5
Goldman, R.D.6
Greene, W.C.7
-
12
-
-
0037501357
-
Co-translational, intraribosomal cleavage of polypeptides by the foot-and-mouth disease virus 2A peptide
-
DOI 10.1074/jbc.M211644200
-
F.P. de, L.E. Hughes, M.D. Ryan, and J.D. Brown Co-translational, intraribosomal cleavage of polypeptides by the foot-and-mouth disease virus 2A peptide J. Biol. Chem. 278 2003 11441 11448 (Pubitemid 36792703)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11441-11448
-
-
De Felipe, P.1
Hughes, L.E.2
Ryan, M.D.3
Brown, J.D.4
-
13
-
-
15244346492
-
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells
-
DOI 10.1182/blood-2004-03-0798
-
P.M. De, E. Montini, F.R. Santoni de Sio, F. Benedicenti, A. Gentile, E. Medico, and L. Naldini Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells Blood 105 2005 2307 2315 (Pubitemid 40387024)
-
(2005)
Blood
, vol.105
, Issue.6
, pp. 2307-2315
-
-
De Palma, M.1
Montini, E.2
Santoni De Sio, F.R.3
Benedicenti, F.4
Gentile, A.5
Medico, E.6
Naldini, L.7
-
14
-
-
84857581038
-
Retroviruses and associated human diseases
-
B.W. Mahy, 10th edn. Hodder Arnold London
-
C.S. Dezzutti, W. Heneine, R.S. Boneva, and T.M. Folks Retroviruses and associated human diseases B.W. Mahy, Topley & Wilson's Microbiology and Microbial Infections: Virology 10th edn. 2007 Hodder Arnold London 1284 1303
-
(2007)
Topley & Wilson's Microbiology and Microbial Infections: Virology
, pp. 1284-1303
-
-
Dezzutti, C.S.1
Heneine, W.2
Boneva, R.S.3
Folks, T.M.4
-
15
-
-
0035015174
-
Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: A putative ribosomal 'skip'
-
M.L. Donnelly, G. Luke, A. Mehrotra, X. Li, L.E. Hughes, D. Gani, and M.D. Ryan Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: A putative ribosomal 'skip' J. Gen. Virol. 82 2001 1013 1025 (Pubitemid 32454602)
-
(2001)
Journal of General Virology
, vol.82
, Issue.5
, pp. 1013-1025
-
-
Donnelly, M.L.L.1
Luke, G.2
Mehrotra, A.3
Li, X.4
Hughes, L.E.5
Gani, D.6
Ryan, M.D.7
-
16
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
T. Dull, R. Zufferey, M. Kelly, R.J. Mandel, M. Nguyen, D. Trono, and L. Naldini A third-generation lentivirus vector with a conditional packaging system J. Virol. 72 1998 8463 8471 (Pubitemid 28471781)
-
(1998)
Journal of Virology
, vol.72
, Issue.11
, pp. 8463-8471
-
-
Dull, T.1
Zufferey, R.2
Kelly, M.3
Mandel, R.J.4
Nguyen, M.5
Trono, D.6
Naldini, L.7
-
17
-
-
27744489220
-
Silencing and variegation of gammaretrovirus and lentivirus vectors
-
DOI 10.1089/hum.2005.16.1241
-
J. Ellis Silencing and variegation of gammaretrovirus and lentivirus vectors Hum. Gene Ther. 16 2005 1241 1246 (Pubitemid 41611651)
-
(2005)
Human Gene Therapy
, vol.16
, Issue.11
, pp. 1241-1246
-
-
Ellis, J.1
-
18
-
-
0033937095
-
Type and position of promoter elements in retroviral vectors have substantial effects on the expression level of an enhanced green fluorescent protein reporter gene
-
M. Flasshove, W. Bardenheuer, A. Schneider, G. Hirsch, P. Bach, C. Bury, T. Moritz, S. Seeber, and B. Opalka Type and position of promoter elements in retroviral vectors have substantial effects on the expression level of an enhanced green fluorescent protein reporter gene J. Cancer Res. Clin. Oncol. 126 2000 391 399 (Pubitemid 30436375)
-
(2000)
Journal of Cancer Research and Clinical Oncology
, vol.126
, Issue.7
, pp. 391-399
-
-
Flasshove, M.1
Bardenheuer, W.2
Schneider, A.3
Hirsch, G.4
Bach, P.5
Bury, C.6
Moritz, T.7
Seeber, S.8
Opalka, B.9
-
19
-
-
0034040751
-
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
-
DOI 10.1038/76095
-
A. Follenzi, L.E. Ailles, S. Bakovic, M. Geuna, and L. Naldini Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences Nat. Genet. 25 2000 217 222 (Pubitemid 30394997)
-
(2000)
Nature Genetics
, vol.25
, Issue.2
, pp. 217-222
-
-
Follenzi, A.1
Ailles, L.E.2
Bakovic, S.3
Geuna, M.4
Naldini, L.5
-
20
-
-
0030845528
-
Recombinant retroviruses Pseudotyped with the vesicular stomatitis virus G glycoprotein mediate both stable gene transfer and pseudotransduction in human peripheral blood lymphocytes
-
H.F. Gallardo, C. Tan, D. Ory, and M. Sadelain Recombinant retroviruses pseudotyped with the vesicular stomatitis virus G glycoprotein mediate both stable gene transfer and pseudotransduction in human peripheral blood lymphocytes Blood 90 1997 952 957 (Pubitemid 27314127)
-
(1997)
Blood
, vol.90
, Issue.3
, pp. 952-957
-
-
Gallardo, H.F.1
Tan, C.2
Ory, D.3
Sadelain, M.4
-
21
-
-
0028839344
-
HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase
-
P. Gallay, S. Swingler, J. Song, F. Bushman, and D. Trono HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase Cell 83 1995 569 576
-
(1995)
Cell
, vol.83
, pp. 569-576
-
-
Gallay, P.1
Swingler, S.2
Song, J.3
Bushman, F.4
Trono, D.5
-
22
-
-
0030987672
-
HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway
-
DOI 10.1073/pnas.94.18.9825
-
P. Gallay, T. Hope, D. Chin, and D. Trono HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway Proc. Natl. Acad. Sci. USA 94 1997 9825 9830 (Pubitemid 27408149)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.18
, pp. 9825-9830
-
-
Gallay, P.1
Hope, T.2
Chin, D.3
Trono, D.4
-
23
-
-
33747453473
-
Insulators: Exploiting transcriptional and epigenetic mechanisms
-
DOI 10.1038/nrg1925, PII NRG1925
-
M. Gaszner, and G. Felsenfeld Insulators: Exploiting transcriptional and epigenetic mechanisms Nat. Rev. Genet. 7 2006 703 713 (Pubitemid 44260006)
-
(2006)
Nature Reviews Genetics
, vol.7
, Issue.9
, pp. 703-713
-
-
Gaszner, M.1
Felsenfeld, G.2
-
24
-
-
0017710978
-
Characteristics of a human cell line transformed by DNA from human adenovirus type 5
-
F.L. Graham, J. Smiley, W.C. Russell, and R. Nairn Characteristics of a human cell line transformed by DNA from human adenovirus type 5 J. Gen. Virol. 36 1977 59 74
-
(1977)
J. Gen. Virol.
, vol.36
, pp. 59-74
-
-
Graham, F.L.1
Smiley, J.2
Russell, W.C.3
Nairn, R.4
-
25
-
-
51349090473
-
Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1
-
S. Hacein-Bey-Abina, A. Garrigue, G.P. Wang, J. Soulier, A. Lim, E. Morillon, E. Clappier, L. Caccavelli, E. Delabesse, K. Beldjord, V. Asnafi, and E. MacIntyre Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1 J. Clin. Invest. 118 2008 3132 3142
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3132-3142
-
-
Hacein-Bey-Abina, S.1
Garrigue, A.2
Wang, G.P.3
Soulier, J.4
Lim, A.5
Morillon, E.6
Clappier, E.7
Caccavelli, L.8
Delabesse, E.9
Beldjord, K.10
Asnafi, V.11
MacIntyre, E.12
-
26
-
-
0028239060
-
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells
-
DOI 10.1073/pnas.91.15.7311
-
N.K. Heinzinger, M.I. Bukinsky, S.A. Haggerty, A.M. Ragland, V. Kewalramani, M.A. Lee, H.E. Gendelman, L. Ratner, M. Stevenson, and M. Emerman The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells Proc. Natl. Acad. Sci. USA 91 1994 7311 7315 (Pubitemid 24226853)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.15
, pp. 7311-7315
-
-
Heinzinger, N.K.1
Bukrinsky, M.I.2
Haggerty, S.A.3
Ragland, A.M.4
Kewalramani, V.5
Lee, M.-A.6
Gendelman, H.E.7
Ratner, L.8
Stevenson, M.9
Emerman, M.10
-
27
-
-
51349158298
-
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
-
S.J. Howe, M.R. Mansour, K. Schwarzwaelder, C. Bartholomae, M. Hubank, H. Kempski, M.H. Brugman, K. Pike-Overzet, S.J. Chatters, R.D. de, K.C. Gilmour, and S. Adams Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients J. Clin. Invest. 118 2008 3143 3150
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3143-3150
-
-
Howe, S.J.1
Mansour, M.R.2
Schwarzwaelder, K.3
Bartholomae, C.4
Hubank, M.5
Kempski, H.6
Brugman, M.H.7
Pike-Overzet, K.8
Chatters, S.J.9
De, R.D.10
Gilmour, K.C.11
Adams, S.12
-
28
-
-
0038333587
-
Continuous high-titer HIV-1 vector production
-
DOI 10.1038/nbt815
-
Y. Ikeda, Y. Takeuchi, F. Martin, F.L. Cosset, K. Mitrophanous, and M. Collins Continuous high-titer HIV-1 vector production Nat. Biotechnol. 21 2003 569 572 (Pubitemid 36532025)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.5
, pp. 569-572
-
-
Ikeda, Y.1
Takeuchi, Y.2
Martin, F.3
Cosset, F.-L.4
Mitrophanous, K.5
Collins, M.6
-
29
-
-
3242682377
-
Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator
-
DOI 10.1016/j.yexcr.2004.04.037, PII S0014482704002642
-
J. Jakobsson, N. Rosenqvist, L. Thompson, P. Barraud, and C. Lundberg Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator Exp. Cell Res. 298 2004 611 623 (Pubitemid 38950876)
-
(2004)
Experimental Cell Research
, vol.298
, Issue.2
, pp. 611-623
-
-
Jakobsson, J.1
Rosenqvist, N.2
Thompson, L.3
Barraud, P.4
Lundberg, C.5
-
30
-
-
0030669613
-
Gene transfer into marrow repopulating cells: Comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons
-
H.P. Kiem, S. Heyward, A. Winkler, J. Potter, J.M. Allen, A.D. Miller, and R.G. Andrews Gene transfer into marrow repopulating cells: Comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons Blood 90 1997 4638 4645 (Pubitemid 27508472)
-
(1997)
Blood
, vol.90
, Issue.11
, pp. 4638-4645
-
-
Kiem, H.-P.1
Heyward, S.2
Winkler, A.3
Potter, J.4
Allen, J.M.5
Miller, A.D.6
Andrews, R.G.7
-
31
-
-
0034254827
-
Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny
-
C.A. Klug, S. Cheshier, and I.L. Weissman Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny Blood 96 2000 894 901 (Pubitemid 30616853)
-
(2000)
Blood
, vol.96
, Issue.3
, pp. 894-901
-
-
Klug, C.A.1
Cheshier, S.2
Weissman, I.L.3
-
32
-
-
0028055281
-
Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus
-
P.F. Lewis, and M. Emerman Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus J. Virol. 68 1994 510 516
-
(1994)
J. Virol.
, vol.68
, pp. 510-516
-
-
Lewis, P.F.1
Emerman, M.2
-
33
-
-
0000557449
-
Human immunodeficiency viruses and their replication
-
D.M. Knipe, P.M. Howely, Raven Press New York
-
P.A. Luciw Human immunodeficiency viruses and their replication D.M. Knipe, P.M. Howely, Field's Virology 1996 Raven Press New York 1881 1952
-
(1996)
Field's Virology
, pp. 1881-1952
-
-
Luciw, P.A.1
-
34
-
-
79952688973
-
Large-scale manufacture and characterization of a lentiviral vector produced for clinical ex vivo gene therapy application
-
O.W. Merten, S. Charrier, N. Laroudie, S. Fauchille, C. Dugue, C. Jenny, M. Audit, M.A. Zanta-Boussif, H. Chautard, M. Radrizzani, G. Vallanti, and L. Naldini Large-scale manufacture and characterization of a lentiviral vector produced for clinical ex vivo gene therapy application Hum. Gene Ther. 22 2011 343 356
-
(2011)
Hum. Gene Ther.
, vol.22
, pp. 343-356
-
-
Merten, O.W.1
Charrier, S.2
Laroudie, N.3
Fauchille, S.4
Dugue, C.5
Jenny, C.6
Audit, M.7
Zanta-Boussif, M.A.8
Chautard, H.9
Radrizzani, M.10
Vallanti, G.11
Naldini, L.12
-
35
-
-
0001319673
-
Development and applications of retroviral vectors
-
J.M. Coffin, S.H. Hughes, H. Varmus, Cold Spring Harbor Laboratory New York 2nd edn
-
A.D. Miller Development and applications of retroviral vectors J.M. Coffin, S.H. Hughes, H. Varmus, Retroviruses 1997 Cold Spring Harbor Laboratory New York 437 473 2nd edn
-
(1997)
Retroviruses
, pp. 437-473
-
-
Miller, A.D.1
-
36
-
-
0024460181
-
Improved retroviral vectors for gene transfer and expression
-
A.D. Miller, and G.J. Rosman Improved retroviral vectors for gene transfer and expression Biotechniques 7 1989 980 986
-
(1989)
Biotechniques
, vol.7
, pp. 980-986
-
-
Miller, A.D.1
Rosman, G.J.2
-
37
-
-
0031666744
-
Development of a self-inactivating lentivirus vector
-
H. Miyoshi, U. Blomer, M. Takahashi, F.H. Gage, and I.M. Verma Development of a self-inactivating lentivirus vector J. Virol. 72 1998 8150 8157
-
(1998)
J. Virol.
, vol.72
, pp. 8150-8157
-
-
Miyoshi, H.1
Blomer, U.2
Takahashi, M.3
Gage, F.H.4
Verma, I.M.5
-
38
-
-
0034170820
-
IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector
-
H. Mizuguchi, Z. Xu, A. Ishii-Watabe, E. Uchida, and T. Hayakawa IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector Mol. Ther. 1 2000 376 382
-
(2000)
Mol. Ther.
, vol.1
, pp. 376-382
-
-
Mizuguchi, H.1
Xu, Z.2
Ishii-Watabe, A.3
Uchida, E.4
Hayakawa, T.5
-
39
-
-
79954692758
-
Ex vivo gene transfer and correction for cell-based therapies
-
L. Naldini Ex vivo gene transfer and correction for cell-based therapies Nat. Rev. Genet. 12 2011 301 315
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 301-315
-
-
Naldini, L.1
-
40
-
-
33645734405
-
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
-
M.G. Ott, M. Schmidt, K. Schwarzwaelder, S. Stein, U. Siler, U. Koehl, H. Glimm, K. Kuhlcke, A. Schilz, H. Kunkel, S. Naundorf, and A. Brinkmann Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1 Nat. Med. 12 2006 401 409
-
(2006)
Nat. Med.
, vol.12
, pp. 401-409
-
-
Ott, M.G.1
Schmidt, M.2
Schwarzwaelder, K.3
Stein, S.4
Siler, U.5
Koehl, U.6
Glimm, H.7
Kuhlcke, K.8
Schilz, A.9
Kunkel, H.10
Naundorf, S.11
Brinkmann, A.12
-
41
-
-
0034122464
-
Progress with retroviral gene vectors
-
DOI 10.1002/(SICI)1099-1654(200 005/06)10:3<185::AI D-RMV285>3.0.CO;2-8
-
G. Palu, C. Parolin, Y. Takeuchi, and M. Pizzato Progress with retroviral gene vectors Rev. Med. Virol. 10 2000 185 202 (Pubitemid 30311718)
-
(2000)
Reviews in Medical Virology
, vol.10
, Issue.3
, pp. 185-202
-
-
Palu, G.1
Parolin, C.2
Takeuchi, Y.3
Pizzato, M.4
-
42
-
-
0034329445
-
Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code
-
D. Pannell, C.S. Osborne, S. Yao, T. Sukonnik, P. Pasceri, A. Karaiskakis, M. Okano, E. Li, H.D. Lipshitz, and J. Ellis Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code EMBO J. 19 2000 5884 5894
-
(2000)
EMBO J.
, vol.19
, pp. 5884-5894
-
-
Pannell, D.1
Osborne, C.S.2
Yao, S.3
Sukonnik, T.4
Pasceri, P.5
Karaiskakis, A.6
Okano, M.7
Li, E.8
Lipshitz, H.D.9
Ellis, J.10
-
43
-
-
0344783931
-
Minimal number of circulating CD34+ cells to ensure successful leukapheresis and engraftment in autologous peripheral blood progenitor cell transplantation
-
+ cells to ensure successful leukapheresis and engraftment in autologous peripheral blood progenitor cell transplantation Transfusion 38 1998 385 391 (Pubitemid 28213595)
-
(1998)
Transfusion
, vol.38
, Issue.4
, pp. 385-391
-
-
Perez-Simon, J.A.1
Caballero, M.D.2
Corral, M.3
Nieto, M.J.4
Orfao, A.5
Vazquez, L.6
Amigo, M.L.7
Berges, C.8
Gonzalez, M.9
Del Canizo, C.10
San Miguel, J.F.11
-
44
-
-
14044263641
-
+ cells using amphotropic-, GALV-, or RD114-pseudotyped HIV-1-Based vectors from stable producer cells
-
DOI 10.1016/j.ymthe.2004.10.014, PII S1525001604015060
-
+ cells using amphotropic-, GALV-, or RD114-pseudotyped HIV-1-based vectors from stable producer cells Mol. Ther. 11 2005 452 459 (Pubitemid 40277322)
-
(2005)
Molecular Therapy
, vol.11
, Issue.3
, pp. 452-459
-
-
Relander, T.1
Johansson, M.2
Olsson, K.3
Ikeda, Y.4
Takeuchi, Y.5
Collins, M.6
Richter, J.7
-
45
-
-
0027158091
-
Integration of murine leukemia virus DNA depends on mitosis
-
T. Roe, T.C. Reynolds, G. Yu, and P.O. Brown Integration of murine leukemia virus DNA depends on mitosis EMBO J. 12 1993 2099 2108 (Pubitemid 23157725)
-
(1993)
EMBO Journal
, vol.12
, Issue.5
, pp. 2099-2108
-
-
Roe, T.1
Reynolds, T.C.2
Yu, G.3
Brown, P.O.4
-
46
-
-
0036682935
-
+ cells derived from human and nonhuman primates
-
DOI 10.1182/blood-2001-11-0042
-
+ cells derived from human and nonhuman primates Blood 100 2002 823 832 (Pubitemid 34832607)
-
(2002)
Blood
, vol.100
, Issue.3
, pp. 823-832
-
-
Sandrin, V.1
Boson, B.2
Salmon, P.3
Gay, W.4
Negre, D.5
Le Grand, R.6
Trono, D.7
Cosset, F.-L.8
-
47
-
-
78650918644
-
Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells
-
G. Santilli, E. Almarza, C. Brendel, U. Choi, C. Beilin, M.P. Blundell, S. Haria, K.L. Parsley, C. Kinnon, H.L. Malech, J.A. Bueren, and M. Grez Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells Mol. Ther. 19 2011 122 132
-
(2011)
Mol. Ther.
, vol.19
, pp. 122-132
-
-
Santilli, G.1
Almarza, E.2
Brendel, C.3
Choi, U.4
Beilin, C.5
Blundell, M.P.6
Haria, S.7
Parsley, K.L.8
Kinnon, C.9
Malech, H.L.10
Bueren, J.A.11
Grez, M.12
-
48
-
-
0034322479
-
Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors
-
A. Schambach, H. Wodrich, M. Hildinger, J. Bohne, H.G. Krausslich, and C. Baum Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors Mol. Ther. 2 2000 435 445
-
(2000)
Mol. Ther.
, vol.2
, pp. 435-445
-
-
Schambach, A.1
Wodrich, H.2
Hildinger, M.3
Bohne, J.4
Krausslich, H.G.5
Baum, C.6
-
49
-
-
0029623030
-
Autografting with blood progenitor cells: Predictive value of preapheresis blood cell counts on progenitor cell harvest and correlation of the reinfused cell dose with hematopoietic reconstitution
-
DOI 10.1007/s002770050111
-
N. Schwella, W. Siegert, J. Beyer, O. Rick, J. Zingsem, R. Eckstein, S. Serke, and D. Huhn Autografting with blood progenitor cells: Predictive value of preapheresis blood cell counts on progenitor cell harvest and correlation of the reinfused cell dose with hematopoietic reconstitution Ann. Hematol. 71 1995 227 234 (Pubitemid 26020529)
-
(1995)
Annals of Hematology
, vol.71
, Issue.5
, pp. 227-234
-
-
Schwella, N.1
Siegert, W.2
Beyer, J.3
Rick, O.4
Zingsem, J.5
Eckstein, R.6
Serke, S.7
Huhn, D.8
-
51
-
-
0032956732
-
Transduction of human progenitor hematopoietic stem cells by human immunodeficiency virus type 1-based vectors is cell cycle dependent
-
R.E. Sutton, M.J. Reitsma, N. Uchida, and P.O. Brown Transduction of human progenitor hematopoietic stem cells by human immunodeficiency virus type 1-based vectors is cell cycle dependent J. Virol. 73 1999 3649 3660 (Pubitemid 29189806)
-
(1999)
Journal of Virology
, vol.73
, Issue.5
, pp. 3649-3660
-
-
Sutton, R.E.1
Reitsma, M.J.2
Uchida, N.3
Brown, P.O.4
-
52
-
-
39849110286
-
Self-inactivating gammaretroviral vectors for gene therapy of x-linked severe combined immunodeficiency
-
DOI 10.1038/sj.mt.6300393, PII 6300393
-
S.I. Thornhill, A. Schambach, S.J. Howe, M. Ulaganathan, E. Grassman, D. Williams, B. Schiedlmeier, N.J. Sebire, H.B. Gaspar, C. Kinnon, C. Baum, and A.J. Thrasher Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency Mol. Ther. 16 2008 590 598 (Pubitemid 351315000)
-
(2008)
Molecular Therapy
, vol.16
, Issue.3
, pp. 590-598
-
-
Thornhill, S.I.1
Schambach, A.2
Howe, S.J.3
Ulaganathan, M.4
Grassman, E.5
Williams, D.6
Schiedlmeier, B.7
Sebire, N.J.8
Gaspar, H.B.9
Kinnon, C.10
Baum, C.11
Thrasher, A.J.12
-
53
-
-
0033972740
-
Lentiviral vectors: Turning a deadly foe into a therapeutic agent
-
D. Trono Lentiviral vectors: Turning a deadly foe into a therapeutic agent Gene Ther. 7 2000 20 23 (Pubitemid 30077144)
-
(2000)
Gene Therapy
, vol.7
, Issue.1
, pp. 20-23
-
-
Trono, D.1
-
54
-
-
69949150240
-
Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3′LTR
-
F. Urbinati, P. Arumugam, T. Higashimoto, A. Perumbeti, K. Mitts, P. Xia, and P. Malik Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3′LTR Mol. Ther. 17 2009 1527 1536
-
(2009)
Mol. Ther.
, vol.17
, pp. 1527-1536
-
-
Urbinati, F.1
Arumugam, P.2
Higashimoto, T.3
Perumbeti, A.4
Mitts, K.5
Xia, P.6
Malik, P.7
-
55
-
-
0003151659
-
Retroviral virons and genomes
-
J.M. Coffin, S.H. Hughes, H. Varmus, 2nd edn. Cold Spring Harbor Laboratory New York
-
V.M. Vogt Retroviral virons and genomes J.M. Coffin, S.H. Hughes, H. Varmus, Retroviruses 2nd edn. 1997 Cold Spring Harbor Laboratory New York
-
(1997)
Retroviruses
-
-
Vogt, V.M.1
-
56
-
-
34848851094
-
Promoter choice for retroviral vectors: Transcriptional strength versus trans-activation potential
-
DOI 10.1089/hum.2007.067
-
E.L. Weber, and P.M. Cannon Promoter choice for retroviral vectors: Transcriptional strength versus trans-activation potential Hum. Gene Ther. 18 2007 849 860 (Pubitemid 47502850)
-
(2007)
Human Gene Therapy
, vol.18
, Issue.9
, pp. 849-860
-
-
Weber, E.L.1
Cannon, P.M.2
-
57
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
DOI 10.1126/science.1083413
-
X. Wu, Y. Li, B. Crise, and S.M. Burgess Transcription start regions in the human genome are favored targets for MLV integration Science 300 2003 1749 1751 (Pubitemid 36712571)
-
(2003)
Science
, vol.300
, Issue.5626
, pp. 1749-1751
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
-
58
-
-
0028982237
-
Inducible, high-level production of infectious murine leukemia retroviral vector particles pseudotyped with vesicular stomatitis virus G envelope protein
-
Y. Yang, E.F. Vanin, M.A. Whitt, M. Fornerod, R. Zwart, R.D. Schneiderman, G. Grosveld, and A.W. Nienhuis Inducible, high-level production of infectious murine leukemia retroviral vector particles pseudotyped with vesicular stomatitis virus G envelope protein Hum. Gene Ther. 6 1995 1203 1213
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1203-1213
-
-
Yang, Y.1
Vanin, E.F.2
Whitt, M.A.3
Fornerod, M.4
Zwart, R.5
Schneiderman, R.D.6
Grosveld, G.7
Nienhuis, A.W.8
-
59
-
-
67349202780
-
Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: Application to the gene therapy of WAS
-
M.A. Zanta-Boussif, S. Charrier, A. Brice-Ouzet, S. Martin, P. Opolon, A.J. Thrasher, T.J. Hope, and A. Galy Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: Application to the gene therapy of WAS Gene Ther. 16 2009 605 619
-
(2009)
Gene Ther.
, vol.16
, pp. 605-619
-
-
Zanta-Boussif, M.A.1
Charrier, S.2
Brice-Ouzet, A.3
Martin, S.4
Opolon, P.5
Thrasher, A.J.6
Hope, T.J.7
Galy, A.8
-
60
-
-
0034646513
-
HIV-1 genome nuclear import is mediated by a central DNA flap
-
DOI 10.1016/S0092-8674(00)80828-4
-
V. Zennou, C. Petit, D. Guetard, U. Nerhbass, L. Montagnier, and P. Charneau HIV-1 genome nuclear import is mediated by a central DNA flap Cell 101 2000 173 185 (Pubitemid 32004745)
-
(2000)
Cell
, vol.101
, Issue.2
, pp. 173-185
-
-
Zennou, V.1
Petit, C.2
Guetard, D.3
Nerhbass, U.4
Montagnier, L.5
Charneau, P.6
-
61
-
-
34548843603
-
Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells
-
DOI 10.1182/blood-2006-12-060814
-
F. Zhang, S.I. Thornhill, S.J. Howe, M. Ulaganathan, A. Schambach, J. Sinclair, C. Kinnon, H.B. Gaspar, M. Antoniou, and A.J. Thrasher Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells Blood 110 2007 1448 1457 (Pubitemid 47443959)
-
(2007)
Blood
, vol.110
, Issue.5
, pp. 1448-1457
-
-
Zhang, F.1
Thornhill, S.I.2
Howe, S.J.3
Ulaganathan, M.4
Schambach, A.5
Sinclair, J.6
Kinnon, C.7
Gaspar, H.B.8
Antoniou, M.9
Thrasher, A.J.10
-
62
-
-
77956265818
-
A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation-mediated silencing of lentiviral vectors
-
F. Zhang, A.R. Frost, M.P. Blundell, O. Bales, M.N. Antoniou, and A.J. Thrasher A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation-mediated silencing of lentiviral vectors Mol. Ther. 18 2010 1640 1649
-
(2010)
Mol. Ther.
, vol.18
, pp. 1640-1649
-
-
Zhang, F.1
Frost, A.R.2
Blundell, M.P.3
Bales, O.4
Antoniou, M.N.5
Thrasher, A.J.6
-
63
-
-
4344693571
-
Cytokines: Value-Added products in hematopoietic stem cell gene therapy
-
DOI 10.1016/j.ymthe.2004.05.025, PII S1525001604001947
-
S.P. Zielske, and S.E. Braun Cytokines: Value-added products in hematopoietic stem cell gene therapy Mol. Ther. 10 2004 211 219 (Pubitemid 39117866)
-
(2004)
Molecular Therapy
, vol.10
, Issue.2
, pp. 211-219
-
-
Zielske, S.P.1
Braun, S.E.2
-
64
-
-
0032978712
-
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
-
R. Zufferey, J.E. Donello, D. Trono, and T.J. Hope Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors J. Virol. 73 1999 2886 2892 (Pubitemid 29135675)
-
(1999)
Journal of Virology
, vol.73
, Issue.4
, pp. 2886-2892
-
-
Zufferey, R.1
Donello, J.E.2
Trono, D.3
Hope, T.J.4
|