An American founder mutation in MLH1

International Journal of Cancer

Volumn 130, Issue 9, 2012, Pages 2088-2095

  Tomsic, Jerneja ^a   Liyanarachchi, Sandya ^a   Hampel, Heather ^a   Morak, Monika ^b,c   Thomas, Brittany C ^d   Raymond, Victoria M ^e,f   Chittenden, Anu ^g   Schackert, Hans K ^h   Gruber, Stephen B ^e,f   Syngal, Sapna ^g,i   Viel, Alessandra ^j   Holinski Feder, Elke ^b,c   Thibodeau, Stephen N ^d   De La Chapelle, Albert ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c Center of Medical Genetics and Primary Health Care   (Armenia)

^d Mayo Clinic   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^g DANA FARBER CANCER INSTITUTE   (United States)

^h DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

ⁱ BRIGHAM AND WOMEN S HOSPITAL   (United States)

^j CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

more..

Author keywords

colon cancer; founder mutation; genetic predisposition; MLH1

Indexed keywords

ADENINE; GUANINE; METHIONINE; VALINE;

ADULT; AGED; AMERICAN; ARTICLE; CANCER DIAGNOSIS; CANCER GENETICS; CONTROLLED STUDY; ETHNIC GROUP; FAMILY STUDY; FEMALE; GENE; GENE MUTATION; GENETIC VARIABILITY; GERMAN; HAPLOTYPE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HETEROZYGOTE; HUMAN; ITALIAN; ITALY; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; MLH1 GENE; MUTATIONAL ANALYSIS; POPULATION GENETICS; POPULATION RESEARCH; PREDICTION; PRIORITY JOURNAL; UNITED STATES;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; ALLELES; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; EXONS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERMANY; HAPLOTYPES; HETEROZYGOTE; HUMANS; INTRONS; ITALY; MALE; MIDDLE AGED; MUTATION; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA SPLICE SITES; UNITED STATES;

EID: 84857505188     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26233     Document Type: Article

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