A common MSH2 mutation in English and North American HNPCC families: Origin, phenotypic expression, and sex specific differences in colorectal cancer

Journal of Medical Genetics

Volumn 36, Issue 2, 1999, Pages 97-102

  Froggatt, Nicola J ^a   Green, Jane ^b   Brassett, Cecilia ^a   Evans, D Gareth R ^c   Bishop, D Timothy ^d   Kolodner, Richard ^e   Maher, Eamonn R ^a,f  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^c ST MARY S HOSPITAL   (United Kingdom)

^d ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^e DANA FARBER CANCER INSTITUTE   (United States)

^f UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Colorectal cancer; HNPCC; MSH2 mutation

Indexed keywords

MESSENGER RNA;

ADULT; ARTICLE; CANADA; CANCER RISK; CANCER SUSCEPTIBILITY; COLORECTAL CANCER; DNA REPAIR; ENDOMETRIUM CANCER; EXON; FEMALE; FOUNDER EFFECT; GENE MUTATION; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR GENETICS; NORTH AMERICA; OVARY CANCER; PHENOTYPE; PRIORITY JOURNAL; SEX DIFFERENCE; UNITED KINGDOM;

AGE FACTORS; CHROMOSOMES, HUMAN, PAIR 2; COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA-BINDING PROTEINS; ENDOMETRIAL NEOPLASMS; ENGLAND; FEMALE; FOUNDER EFFECT; GENE EXPRESSION; HAPLOTYPES; HUMANS; MALE; MUTS HOMOLOG 2 PROTEIN; NORTH AMERICA; OVARIAN NEOPLASMS; PHENOTYPE; POINT MUTATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTO-ONCOGENE PROTEINS; RISK FACTORS; SEQUENCE ANALYSIS, DNA; SEX FACTORS;

EID: 0033039550     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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