Low-resolution molecular models reveal the oligomeric state of the PPAR and the conformational organization of its domains in solution

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Bernardes, Amanda ^a   Batista, Fernanda A H ^a   de Oliveira Neto, Mario ^a   Figueira, Ana Carolina M ^b   Webb, Paul ^c   Saidemberg, Daniel ^d,e   Palma, Mario S ^d,e   Polikarpov, Igor ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b BRAZILIAN CENTER FOR RESEARCH IN ENERGY AND MATERIALS CNPEM   (Brazil)

^c HOUSTON METHODIST HOSPITAL   (United States)

^d SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^e National Institute of Science and Technology on Immunology (INCT/iii)   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; DIMER; MONOMER; OLIGOMER; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RETINOID X RECEPTOR; RETINOID X RECEPTOR ALPHA; DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ARTICLE; CONTROLLED STUDY; DNA BINDING; HUMAN; LOW RESOLUTION MOLECULAR MODEL; MOLECULAR MODEL; NONHUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; DEUTERIUM HYDROGEN EXCHANGE; DNA RESPONSIVE ELEMENT; GEL CHROMATOGRAPHY; GENETICS; HYDRODYNAMICS; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SMALL ANGLE SCATTERING; SOLUTION AND SOLUBILITY; X RAY DIFFRACTION;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, GEL; DEUTERIUM EXCHANGE MEASUREMENT; DNA; HUMANS; HYDRODYNAMICS; MASS SPECTROMETRY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PPAR GAMMA; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RESPONSE ELEMENTS; RETINOID X RECEPTOR ALPHA; SCATTERING, SMALL ANGLE; SOLUTIONS; X-RAY DIFFRACTION;

EID: 84857484518     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031852     Document Type: Article

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