Apolipoprotein A1 Is Overexpressed in the Retina of Diabetic Patients

American Journal of Ophthalmology

Volumn 147, Issue 2, 2009, Pages

  Simó, Rafael ^a,b   García Ramírez, Marta ^a,b   Higuera, Mónica ^b   Hernández, Cristina ^a,b  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; MESSENGER RNA;

APOPTOSIS; ARTICLE; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; DENSITOMETRY; DIABETES MELLITUS; GLIA CELL; HUMAN; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; NERVE DEGENERATION; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RETINA; RETINA INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 58249114029     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2008.08.009     Document Type: Article

References (27)

1. Congdon N.G., Friedman D.S., and Lietman T. Important causes of visual impairment in the world today. JAMA 290 (2003) 2057-2060
2. Miljanovic B., Glynn R.J., Nathan D.M., et al. A prospective study of serum lipids and risk of diabetic macular edema in type 1 diabetes. Diabetes 53 (2004) 2883-2892
3. Keech A.C., Mitchell P., Summanen P.A., and FIELD Study Investigators. Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD Study): a randomised controlled trial. Lancet 370 (2007) 1687-1697
4. Simó R., and Hernández C. Fenofibrate for diabetic retinopathy. Lancet 370 (2007) 1667-1668
5. Tserentsoodol N., Sztein J., Campos M., et al. Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process. Mol Vis 12 (2006) 1306-1318
6. Tserentsoodol N., Gordiyenko N.V., Pascual I., et al. Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors. Mol Vis 12 (2006) 1319-1333
7. García-Ramirez M., Canals F., Hernández C., et al. Proteomic analysis of human vitreous fluid by fluorescence-based difference gel electrophoresis (DIGE): a new strategy for identifying potential candidates in the pathogenesis of proliferative diabetic retinopathy. Diabetologia 50 (2007) 1294-1303
8. Simó R., Higuera M., García-Ramírez M., et al. Elevation of apolipoprotein A-I and apolipoprotein H levels in the vitreous fluid and overexpression in the retina of diabetic patients. Arch Ophthalmol 126 (2008) 1076-1081
9. Sall J.W., Klisovic D.D., O'Dorisio M.S., et al. Somatostatin inhibits IGF-1 mediated induction of VEGF in human retinal pigment epithelial cells. Exp Eye Res 79 (2004) 465-476
10. Carrasco E., Hernández C., Miralles A., et al. Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegeneration. Diabetes Care 30 (2007) 2902-2908
11. García-Ramírez M., Hernández C., and Simó R. Expression of erithropoietin and its receptor in the human retina. A comparative study of diabetic and nondiabetic subjects. Diabetes Care 31 (2008) 1189-1194
12. Sanges D., Comitato A., Tammaro R., et al. Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc Natl Acad Sci USA 103 (2006) 17366-17371
13. Landi S., Cenni M.C., Maffei L., et al. Environmental enrichment effects on development of retinal ganglion cell dendritic stratification require retinal BDNF. PLoS ONE 2 (2007) e346
14. Kawai S., Nakajima T., Hokari S., et al. Apolipoprotein A-I concentration in tears in diabetic retinopathy. Ann Clin Biochem 39 (2002) 56-61
15. Ishida B.Y., Duncan K.G., Bailey K.R., et al. High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture. Br J Ophthalmol 90 (2006) 616-620
16. Girotti A.W., and Kriska T. Role of lipid hydroxiperoxides in photo-oxidative stress signaling. Antioxid Redox Signal 6 (2004) 301-310
17. Mackness M.I., and Durrington P.N. HDL, its enzymes and its potential to influence lipid peroxidation. Atherosclerosis 115 (1995) 243-253
18. Robbesyn F., Augé N., Vindis C., et al. High-density lipoproteins prevent the oxidized low-density lipoprotein-induced epidermal growth factor receptor activation and subsequent matrix metalloproteinase-2 upregulation. Arterioscler Thromb Vasc Biol 25 (2005) 1206-1212
19. Ng D.S., Leiter L.A., Vezina C., et al. Apolipoprotein A-I Q[-2]X causing isolated apolipoprotein A-I deficiency in a family with analphalipoproteinemia. J Clin Invest 93 (1994) 223-229
20. Ng D.S., O'Connor P.W., Mortimer C.B., et al. Case report: retinopathy and neuropathy associated with complete apolipoprotein A-I deficiency. Am J Med Sci 312 (1996) 30-33
21. Li C.M., Chung B.H., Presley J.B., et al. Lipoprotein-like particles and cholesteryl esters in human Bruch's membrane: initial characterization. Invest Ophthalmol Vis Sci 46 (2005) 2576-2586
22. Hayes K.C., Lindsey S., Stephan Z.F., et al. Retinal pigment epithelium possesses both LDL and scavenger receptor activity. Invest Ophthalmol Vis Sci 30 (1989) 225-232
23. Duncan K.G., Bailey K.R., Kane J.P., et al. Human retinal pigment epithelial cells express scavenger receptors BI and BII. Biochem Biophys Res Commun 292 (2002) 1017-1022
24. Curcio C.A., Millican C.L., Bailey T., et al. Accumulation of cholesterol with age in human Bruch's membrane. Invest Ophthalmol Vis Sci 42 (2001) 265-274
25. Li C.M., Clark M.E., Chimento M.F., et al. Apolipoprotein localization in isolated drusen and retinal apolipoprotein gene expression. Invest Ophthalmol Vis Sci 47 (2006) 3119-3128
26. Leung H., Wang J.J., Rochtchina E., et al. Dyslipidaemia and microvascular disease in the retina. Eye 19 (2005) 861-868
27. Zhang J., and McGwin Jr. G. Association of statin use with the risk of developing diabetic retinopathy. Arch Ophthalmol 125 (2007) 1096-1099