T7 RNA polymerases backed up by covalently trapped proteins catalyze highly error prone transcription

Journal of Biological Chemistry

Volumn 287, Issue 9, 2012, Pages 6562-6572

  Nakano, Toshiaki ^a   Ouchi, Ryo ^a   Kawazoe, Junya ^a   Pack, Seung Pil ^b   Makino, Keisuke ^c   Ide, Hiroshi ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b Korea University   (South Korea)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; DNA DAMAGING AGENTS; DNA LESIONS; DNA-BINDING PROTEIN; DNA-TEMPLATE; ERROR PRONES; IMMOBILIZED PROTEINS; IN-VITRO; MUTUAL INTERACTION; PROXIMAL POSITIONS; RNA POLYMERASE; SEQUENCE ANALYSIS; SITE-SPECIFIC; TRANSCRIPTIONAL FIDELITY; TRANSLESION;

DNA; GENES; RNA; TRANSCRIPTION;

PROTEINS;

DNA; RNA POLYMERASE; T7 RNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME MECHANISM; GEL MOBILITY SHIFT ASSAY; IN VITRO STUDY; MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION;

BACTERIOPHAGE T7; CATALYSIS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; DNA-DIRECTED RNA POLYMERASES; MUTAGENESIS; MUTATION; TRANSCRIPTION, GENETIC; VIRAL PROTEINS;

EID: 84857463889     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.318410     Document Type: Article

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