Radiobiology dedicated to endothelium;Radiobiologie appliquée à l'endothélium

Cancer/Radiotherapie

Volumn 16, Issue 1, 2012, Pages 11-15

  Supiot, S ^a,b,c   Paris, F ^a,b,c  

^a Team 12   (France)

^b UNIVERSITÉ DE NANTES   (France)

^c UMR INSERM U892 CNRS 6299   (France)

Author keywords

Apoptosis; Ceramide; Endothelial cell; Ionizing radiation

Indexed keywords

CANCER RADIOTHERAPY; ENDOTHELIUM; PRIORITY JOURNAL; RADIOBIOLOGY; RADIOSENSITIVITY; SHORT SURVEY;

ANGIOGENESIS INHIBITORS; APOPTOSIS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; RADIOTHERAPY DOSAGE;

EID: 84857448727     PISSN: 12783218     EISSN: 17696658     Source Type: Journal    
DOI: 10.1016/j.canrad.2011.10.006     Document Type: Short Survey

References (41)

1. Mervoyer A., Lisbonna A., Rio E., Mahé M. évaluation de la dose reçue par les organes à risque. Cancer Radiother 2010, 14:232-235.
2. Andreyev J. Gastrointestinal symptoms after pelvic radiotherapy: a new understanding to improve management of symptomatic patients. Lancet Oncol 2007, 8:1007-1017.
3. Cosset J.M. Hypofractionnement en radiothérapie: le retour ?. Cancer Radiother 2005, 9366-9373.
4. McGarry R.C., Papiez L., Williams M., Whitford T., Timmerman R.D. Stereotactic body radiation therapy of early-stage non-small-cell lung carcinoma: phase I study. Int J Radiat Oncol Biol Phys 2005, 63:1010-1015.
5. Ahmed K.M., Li J.J. ATM-NF-kappaB connection as a target for tumor radiosensitization. Curr Cancer Drug Targets 2007, 7:335-342.
6. Durand R.E. Keynote address: the influence of microenvironmental factors on the activity of radiation and drugs. Int J Radiat Oncol Biol Phys 1991, 20:253-258.
7. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971, 285:1182-1186.
8. Carmeliet P. Angiogenesis in life, disease and medicine. Nature 2005, 438:932-936.
9. The Angiogenesis Foundation (page d'accueil sur Internet). Cambridge, MA: The Angiogenesis Foundation ; ©2011. Disponible à l'adresse: . (Accès le 17/10/2011). http://www.angio.org/index.php.
10. Chen H.X., Cleck J.N. Adverse effects of anticancer agents that target the VEGF pathway. Nat Rev Clin Oncol 2009, 6:465-477.
11. Garcia-Barros M., Paris F., Cordon-Cardo C., Lyden D., Rafii S., Haimovitz-Friedman A., et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003, 300:1155-1159.
12. Corre I., Niaudet C., Paris F. Plasma membrane signaling induced by ionizing radiation. Mutat Res 2010, 704:61-67.
13. Maj J.G., Paris F., Haimovitz-Friedman A., Venkatraman E., Kolesnick R., Fuks Z. Microvascular function regulates intestinal crypt response to radiation. Cancer Res 2003, 63:4338-4341.
14. Paris F., Fuks Z., Kang A., Capodieci P., Juan G., Ehleiter D., et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 2001, 293:293-297.
15. Kirsch D.G., Santiago P.M., di Tomaso E., Sullivan J.M., Hou W.S., Dayton T., et al. p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis. Science 2010, 327:593-596.
16. Bonnaud S., Niaudet C., Legoux F., Corre I., Delpon G., Saulquin X., et al. Sphingosine-1-phosphate activates the AKT pathway to protect small intestines from radiation-induced endothelial apoptosis. Cancer Res 2010, 70:9905-9915.
17. Qiu W., Carson-Walter E.B., Liu H., Epperly M., Greenberger J.S., Zambetti G.P., et al. PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome. Cell Stem Cell 2008, 2:576-583.
18. Cho C.H., Kammerer R.A., Lee H.J., Yasunaga K., Kim K.T., Choi H.H., et al. Designed angiopoietin-1 variant, COMP-Ang1, protects against radiation-induced endothelial cell apoptosis. Proc Natl Acad Sci U S A 2004, 101:5553-5558.
19. Rotolo J.A., Maj J.G., Feldman R., Ren D., Haimovitz-Friedman A., Cordon-Cardo C., et al. Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa. Int J Radiat Oncol Biol Phys 2008, 70:804-815.
20. Wang J., Boerma M., Fu Q., Hauer-Jensen M. Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy. World J Gastroenterol 2007, 13:3047-3355.
21. Stewart F.A., Te Poele J.A., Van der Wal A.F., Oussoren Y.G., Van Kleef E.M., Kuin A., et al. Radiation nephropathy: the link between functional damage and vascular mediated inflammatory and thrombotic changes. Acta Oncol 2001, 40:952-957.
22. Gabrys D., Greco O., Patel G., Prise K.M., Tozer G.M., Kanthou C. Radiation effects on the cytoskeleton of endothelial cells and endothelial monolayer permeability. Int J Radiat Oncol Biol Phys 2007, 69:1553-1562.
23. Rousseau M., Gaugler M.H., Rodallec A., Bonnaud S., Paris F., Corre I. RhoA GTPase regulates radiation-induced alterations in endothelial cell adhesion and migration. Biochem Biophys Res Commun 2011, 414:750-755. [Epub 2011 Oct 6. PMID: 22001926].
24. Gu Q., Wang D., Wang X., Peng R., Liu J., Jiang T., et al. Basic fibroblast growth factor inhibits radiation-induced apoptosis of HUVECs. I. The PI3K/AKT pathway and induction of phosphorylation of BAD. Radiat Res 2004, 161:692-702.
25. Bonnaud S., Niaudet C., Pottier G., Gaugler M.H., Millour J., Barbet J., et al. Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage-induced mitotic death. Cancer Res 2007, 67:1803-1811.
26. Gupta V.K., Jaskowiak N.T., Beckett M.A., Mauceri H.J., Grunstein J., Johnson R.S., et al. Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer J 2002, 8:47-54.
27. Cotrim A.P., Sowers A., Mitchell J.B., Baum B.J. Prevention of irradiation-induced salivary hypofunction by microvessel protection in mouse salivary glands. Mol Ther 2007, 15:2101-2106.
28. Gorski D.H., Mauceri H.J., Salloum R.M., Gately S., Hellman S., Beckett M.A., et al. Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin. Cancer Res 1998, 58:5686-5689.
29. Mauceri H.J., Hanna N.N., Beckett M.A., Gorski D.H., Staba M.J., Stellato K.A., et al. Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature 1998, 394:287-291.
30. Li J., Huang S., Armstrong E.A., Fowler J.F., Harari P.M. Angiogenesis and radiation response modulation after vascular endothelial growth factor receptor-2 (VEGFR2) blockade. Int J Radiat Oncol Biol Phys 2005, 62:1477-1485.
31. Kobayashi H., Lin P.C. Antiangiogenic and radiotherapy for cancer treatment. Histol Histopathol 2006, 21:1125-1134.
32. Kraeber-Bodere F., Bodet-Milin C., Niaudet C., Sai-Maurel C., Moreau A., Faivre-Chauvet A., et al. Comparative toxicity and efficacy of combined radioimmunotherapy and antiangiogenic therapy in carcinoembryonic antigen-expressing medullary thyroid cancer xenograft. J Nucl Med 2010, 51:624-631.
33. Jain R.K. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005, 307:58-62.
34. Winkler F., Kozin S.V., Tong R.T., Chae S.S., Booth M.F., Garkavtsev I., et al. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell 2004, 6:553-563.
35. Moeller B.J., Cao Y., Li C.Y., Dewhirst M.W. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. Cancer Cell 2004, 5:429-441.
36. Truman J.P., Garcia-Barros M., Kaag M., Hambardzumyan D., Stancevic B., Chan M., et al. Endothelial membrane remodeling is obligate for antiangiogenic radiosensitization during tumor radiosurgery. PLoS One 2010, 5:e12310.
37. Gutin P.H., Iwamoto F.M., Beal K., Mohile N.A., Karimi S., Hou B.L., et al. Safety and efficacy of bevacizumab with hypofractionated stereotactic irradiation for recurrent malignant gliomas. Int J Radiat Oncol Biol Phys 2009, 75:156-163.
38. Staehler M., Haseke N., Nuhn P., Tullmann C., Karl A., Siebels M., et al. Simultaneous antiangiogenic therapy and single-fraction radiosurgery in clinically relevant metastases from renal cell carcinoma. BJU Int 2011, 108:673-678.
39. Imaizumi N., Monnier Y., Hegi M., Mirimanoff R.O., Ruegg C. Radiotherapy suppresses angiogenesis in mice through TGF-betaRI/ALK5-dependent inhibition of endothelial cell sprouting. PLoS One 2010, 5:e11084.
40. Ahn G.O., Brown J.M. Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells. Cancer Cell 2008, 13:193-205.
41. Kioi M., Vogel H., Schultz G., Hoffman R.M., Harsh G.R., Brown J.M. Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J Clin Invest 2010, 120:694-705.