Controlled release of IGF-I from a biodegradable matrix improves functional recovery of skeletal muscle from ischemia/reperfusion

Biotechnology and Bioengineering

Volumn 109, Issue 4, 2012, Pages 1051-1059

  Hammers, David W ^a,b   Sarathy, Apurva ^a   Pham, Chantal B ^a   Drinnan, Charles T ^b   Farrar, Roger P ^a   Suggs, Laura J ^b  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b The University of Texas at Austin   (United States)

Author keywords

Muscle regeneration; Protein kinase b; Regenerative medicine; Satellite cells; Tourniquet

Indexed keywords

MUSCLE REGENERATION; PROTEIN KINASE B; REGENERATIVE MEDICINE; SATELLITE CELLS; TOURNIQUET;

ANIMALS; FUNCTION EVALUATION; NEURONS; POLYETHYLENE GLYCOLS; RECOVERY; SYNCHROTRONS;

MUSCLE;

FIBRIN; MACROGOL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIODEGRADABILITY; CONJUGATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE FUNCTION; MUSCLE INJURY; MUSCLE ISCHEMIA; MUSCLE REGENERATION; MYOBLAST; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; REPERFUSION INJURY; SKELETAL MUSCLE; STRUCTURE ANALYSIS; WESTERN BLOTTING;

ABSORBABLE IMPLANTS; ANIMALS; DRUG CARRIERS; DRUG EVALUATION, PRECLINICAL; DRUG IMPLANTS; FIBRIN; GELS; HINDLIMB; INJECTIONS, INTRAMUSCULAR; INSULIN-LIKE GROWTH FACTOR I; MALE; MUSCLE, SKELETAL; PHOSPHATIDYLINOSITOL 3-KINASES; POLYETHYLENE GLYCOLS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TOURNIQUETS;

ANIMALIA; RATTUS;

EID: 84857440738     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24382     Document Type: Article

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