Nutritional modulation of insulin resistance in the true carnivorous cat: A review

Critical Reviews in Food Science and Nutrition

Volumn 52, Issue 2, 2012, Pages 172-182

  Verbrugghe, Adronie ^a   Hesta, Myriam ^a   Daminet, Sylvie ^a   Janssens, Geert P J ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Carnivore; Cat; Insulin resistance; Nutrition

Indexed keywords

ANIMAL TISSUE; CARBOHYDRATE SOURCES; CARNIVORE; CAT; DIABETES MELLITUS; DIETARY FIBERS; DIGESTIVE TRACT; INSULIN RESISTANCE; INSULIN SENSITIVITY; LITERATURE REVIEWS; NATURAL HABITAT; OUTDOOR ENVIRONMENT; PHYSICAL ACTIVITY; PHYSIOLOGICAL ADAPTATIONS; PROTEIN METABOLISM;

CARBOHYDRATES; DIGESTIVE SYSTEM; NUTRITION; TISSUE;

INSULIN;

ANIMALIA; FELIDAE; FELIS CATUS;

ANIMAL; ANIMAL FOOD; CARBOHYDRATE DIET; CAT; CAT DISEASE; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; INSULIN RESISTANCE; METABOLISM; NUTRITIONAL REQUIREMENT; OBESITY; PROTEIN INTAKE; REVIEW;

ANIMAL FEED; ANIMAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ANIMALS; BLOOD GLUCOSE; CAT DISEASES; CATS; DIABETES MELLITUS; DIETARY CARBOHYDRATES; DIETARY PROTEINS; INSULIN RESISTANCE; NUTRITIONAL REQUIREMENTS; OBESITY;

EID: 84857391077     PISSN: 10408398     EISSN: 15497852     Source Type: Journal    
DOI: 10.1080/10408398.2010.499763     Document Type: Review

References (98)

1. Anderson, R. S. (1973). Obesity in the dog and cat. Vet Ann. 14: 183-186.
2. Appleton, D. J., Rand, J. S., Priest, J., Sunvold, G. D., and Vickers, J. R. (2004). Dietary carbohydrate source affects glucose concentrations, insulin secretion, and food intake in overweight cats. Nutr Res. 24: 447-467.
3. Arai, T., Washizu, T., Sako, T., Sasaki, M., andMotoyoshi, S. (1992). D-glucose transport activities in erythrocytes and hepatocytes of dogs, cats and cattle. Comp Biochem Physiol A-Physiol. 102: 285-287.
4. Backus, R. C., Cave, N. J., and Keisler, D. H. (2007). Gonadectomy and high dietary fat but not high dietary carbohydrate induce gains in body weight and fat of domestic cats. Br J Nutr. 98: 641-650.
5. Ballard, F. J. (1965). Glucose utilization in mammalian liver. Comp Biochem Physiol. 14: 437-443.
6. Bartoshuk, L. M., Harned, M. A., and Parks, L. H. (1971). Taste of water in the cat: Effects on sucrose preference. Science. 171: 699-701.
7. Beauchamp, G. K., Maller, O., and Rogers, J. G. (1977). Flavor preferences in cats (Felis-Catus and Panthera Sp). J Comp Physiol Psycol. 91: 1118-1127.
8. Behall, K. M., Scholfield, D. J., Yuhaniak, I., and Canary, J. (1989). Diets containing high amylose vs amylopectin starch: Effects on metabolic variables in human-subjects. Am J Clin Nutr. 49: 337-344.
9. Behall, K. M. and Hallfrisch, J. (2002). Plasma glucose and insulin reduction after consumption of breads varying in amylose content. Eur J Clin Nutr. 56: 913-920.
10. Beidler, L.M., Fishman, I. Y., and Hardiman, C.W. (1955). Species differences in taste responses. Am J Physiol. 181: 235-239.
11. Bennett, N., Greco, D. S., Peterson, M. E., Kirk, C., Mathes, M., and Fettman, M. J. (2006). Comparison of a low carbohydrate-low fiber diet and a moderate carbohydrate-high fiber diet in the management of feline diabetes mellitus. J Feline Med Surg. 8: 73-84.
12. Blaxter, A. C., Cripps, P. J., and Gruffydd-Jones, T. J. (1990). Dietary fiber and postprandial hyperglycemia in normal and diabetic dogs. J Small Anim Pract. 31: 229-233.
13. Bouchard, G. F. and Sunvold, G. D. (2000). Effect of dietary carbohydrate source on postprandial plasma glucose and insulin concentrations in cats. In: Recent Advances in Canine and Feline Nutrition, pp. 91-101. Reinhart, G. A. and Carey, D. P., Eds., Orange Frazer Press, Wilmington, OH.
14. Boudreau, J. C. (1977). Chemical stimulus determinants of cat neural taste responses to meats. J Am Oil Chem Soc. 54: 464-466.
15. Buddington, R. K., Chen, J.W., and Diamond, J. M. (1991). Dietary-regulation of intestinal brush-border sugar and amino-acid-transport in carnivores. Am J Physiol. 261: R793-R801.
16. Carpenter, J. A. (1956). Species differences in taste preferences. J Comp Physiol Psycol. 49: 139-144.
17. Curry, D. L., Morris, J. G., Rogers, Q. R., and Stern, J. S. (1982). Dynamics of insulin and glucagon-secretion by the isolated perfused cat pancreas. Comp Biochem Physiol A-Physiol. 72: 333-338.
18. de-Oliveira, L. D., Carciofi, A. C., Oliveira, M. C. C., Vasconcellos, R. S., Bazolli, R. S., Pereira, G. T., and Prada, F. (2008). Effects of six carbohydrate sources on diet digestibility and postprandial glucose and insulin responses in cats. J Anim Sci. 86: 2237-2246.
19. Delarue, J. and Magnan, C. (2007). Free fatty acids and insulin resistance. Curr Opin Clin Nutr Metab Care. 10: 142-148.
20. Denardin, C. C., Walter, M., da Silva, L. P., Souto, G. D., and Fagundes, C. A. A. (2007). Effect of amylose content of rice varieties on glycemic metabolism and biological responses in rats. Food Chemistry. 105: 1474-1479.
21. de Wilde, R. and Huysentruyt, P. (1983). Digestion of carbohydrates in cats. Tijdschrift Voor Diergeneeskunde. 108: 187-190.
22. Dierenfeld, E. S., Alcorn, H. L., and Jacobsen, K. L. (2002). Nutrient composition of whole vertebrate prey (excluding fish) fed in zoos. http://www.nal.usda.gov/awic/zoo/WholePreyFinal02May29.pdf.
23. Farrow, H. A., Rand, J. S., and Sunvold, G. D. (2002). The effect of high protein, high fat or high carbohydrate diets on postprandial glucose and insulin concentrations in normal cats. J Vet Int Med. 16: 360.
24. Frank, G., Anderson, W., Pazak, H., Hodgkins, E., Ballam, J., and Laflamme, D. (2001). Use of high-protein diet in the management of feline diabetes mellitus. Veterinary Therapeutics. 2: 238-246.
25. Franz, M. J., Bantle, J. P., Beebe, C. A., Brunzell, J. D., Chiasson, J. L., Garg, A., Holzmeister, L. A., Hoogwerf, B., Mayer-Davis, E. et al. (2002). Evidencebased nutrition principles and recommendations for the treatment and prevention of diabetes and related complications. Diabetes Care. 25: 148-198.
26. Frings, H. (1951). Sweet taste in the cat and the taste-spectrum. Experientia. 7: 424-426.
27. Goddard, M. S., Young, G., and Marcus, R. (1984). The effect of amylase content on insulin and glucose responses to ingested rice. Am J Clin Nutr. 39: 388-392.
28. Green, A. S., Ramsey, J. J., Villaverde, C., Asami, D. K., Wei, A., and Fascetti, A. J. (2008).Cats are able to adapt protein oxidation to protein intake provided their requirement for dietary protein is met. J Nutr. 138: 1053-1060.
29. Hall, T. C., Mahony, O. M., Freeman, L. M., and Rozanski, E. A. (2008). Use of low carbohydrate, high protein diets in cats with diabetes mellitus. J Anim Physiol Anim Nutr. 92: 219-220.
30. Hesta, M., Janssens, G. P. J., Debraekeleer, J., and De Wilde, R. (2001). The effect of oligofructose and inulin on faecal characteristics and nutrient digestibility in healthy cats. J Anim Physiol Anim Nutr. 85: 135-141.
31. Hesta, M., Debraekeleer, J., Janssens, G. P. J., and De Wilde, R. (2006). Effects of prebiotics in dog and cat nutrition: A review. In: Trends in Dietary Carbohydrates Research, pp. 179-219. Landlow, M. V., Ed., Nova Science Publishers, Inc., New York.
32. Higgins, J. A. (2004). Resistant starch: Metabolic effects and potential health benefits. J Assoc of Anal Chem Int. 87: 761-768.
33. Hoenig, M., Thomaseth, K., Brandao, J., Waldron, M., and Ferguson, D. C. (2006). Assessment and mathematical modeling of glucose turnover and insulin sensitivity in lean and obese cats. Dom Anim Endocrinol. 31: 373-389.
34. Hoenig, M., Thomaseth, K., Waldron, M., and Ferguson, D. C. (2007a). Fatty acid turnover, substrate oxidation, and heat production in lean and obese cats during the euglycemic hyperinsulinemic clamp. Dom Anim Endocrinol. 32: 329-338.
35. Hoenig, M., Thomaseth, K., Waldron, M., and Ferguson, D. C. (2007b). Insulin sensitivity, fat distribution, and adipocytokine response to different diets in lean and obese cats before and after weight loss. Am J Physiol -Regul Integr Comp Physiol. 292: R227-R234.
36. Holste, L. C., Nelson, R.W., Feldman, E. C., and Bottoms, G. D. (1989). Effect of dry, soft moist, and canned dog foods on postprandial blood-glucose and insulin concentrations in healthy dogs. Am J Vet Res. 50: 984-989.
37. Jenkins, D. J. A., Wolever, T. M. S., Taylor, R. H., Barker, H., Fielden, H., Baldwin, J. M., Bowling, A. C., Newman, H. C., Jenkins, A. L., and Goff, D. V. (1981). Glycemic index of foods - A physiological-basis for carbohydrate exchange. Am J Clin Nutr. 34: 362-366.
38. Johnston, K., Lamport, A., and Batt, R. M. (1993).An unexpected bacterial-flora in the proximal small-intestine of normal cats. Vet Rec. 132: 362-363.
39. Kienzle, E. (1993a). Carbohydrate-metabolism of the cat. 2. Digestion of starch. J Anim Physiol Anim Nutr. 69: 102-114.
40. Kienzle, E. (1993b). Carbohydrate-metabolism of the cat. 1. Activity of amylase in the gastrointestinal-tract of the cat. J Anim Physiol Anim Nutr. 69: 92-101.
41. Kienzle, E. (1993c). Carbohydrate-metabolism of the cat. 4. Activity of maltase, isomaltase, sucrase and lactase in the gastrointestinal-tract in relation to age and diet. J Anim Physiol Anim Nutr. 70: 89-96.
42. Kienzle, E. (1994a). Effect of carbohydrates on digestion in the cat. J Nutr. 124: 2568S-2571S.
43. Kienzle, E. (1994b). Blood sugar levels and renal sugar excretion after the intake of high carbohydrate diets in cats. J Nutr. 124: 2563S-2567S.
44. Kimmel, S. E., Michel, K. E., Hess, R. S., and Ward, C. R. (2000). Effects of insoluble and soluble dietary fiber on glycemic control in dogs with naturally occurring insulin-dependent diabetes mellitus. J Am Vet Med Assoc. 216: 1076-1081.
45. Laflamme, D. P. and Hannah, S. S. (2005). Increased dietary protein promotes fat loss and reduces loss of lean body mass during weight loss in cats. Int J Appl Res Vet Med. 3: 62-68.
46. Leray, V., Siliart, B., Dumon, H., Martin, L., Sergheraert, R., Biourge, V., and Nguyen, P. (2006). Protein intake does not affect insulin sensitivity in normal weight cats. J Nutr. 136: 2028S-2030S.
47. Li, X., Li, W. H., Wang, H., Cao, J., Maehashi, K., Huang, L. Q., Bachmanov, A. A., Reed, D. R., Legrand-Defretin, V. et al. (2005). Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar. Plos Genetics. 1: 27-35.
48. Li, X., Li, W. H., Wang, H., Bayley, D. L., Cao, J., Reed, D. R., Bachmanov, A. A., Huang, L. Q., Legrand-Defretin, V. et al. (2006). Cats lack a sweet taste receptor. J Nutr. 136: 1932S-1934S.
49. Lund, E. M., Armstrong, P. J., Kirk, C. A., and Klausner, J. S. (2005). Prevalence and risk factors for obesity in adult cats from private US veterinary practices. Int J Appl Res Vet Med. 3: 88-96.
50. Lutz, T. A. and Rand, J. S. (1995). Pathogenesis of feline diabetes-mellitus. Vet Clin North Am -Small Anim Pract. 25: 527-552.
51. MacDonald, M. L., Rogers, Q. R., and Morris, J. G. (1984). Nutrition of the domestic cat, a mammalian carnivore. Annu Rev Nutr. 4: 521-562.
52. Mazzaferro, E. M., Greco, D. S., Turner, A. S., and Fettman, M. J. (2003). Treatment of feline diabetes mellitus using an alpha-glucosidase inhibitor and a low-carbohydrate diet. J Feline Med Surg. 5: 183-189.
53. Mcgeachin, R. L. and Akin, J. R. (1979). Amylase levels in the tissues and bodyfluids of the domestic cat (Felis-Catus). Comp Biochem Physiol B-Biochem Molec Biol. 63: 437-439.
54. Morita, T., Kasaoka, S., and Kiriyama, S. (2004). Physiological functions of resistant proteins: Proteins and peptides regulating large bowel fermentation of indigestible polysaccharide. J Assoc of Anal Chem Int. 87: 792-796.
55. Morris, J. G. (2002). Idiosyncratic nutrient requirements of cats appear to be diet-induced evolutionary adaptations. Nutr Res Rev. 15: 153-168.
56. Morris, J. G., Trudell, J., and Pencovic, T. (1977). Carbohydrate digestion by domestic cat (Felis Catus). Br J Nutr. 37: 365-373.
57. Nelson, R.W. (1989). The role of fiber in managing diabetes mellitus. Vet Med. 84: 1156-1160.
58. Nelson, R. W., Ihle, S. L., Lewis, L. D., Salisbury, S. K., Miller, T., Bergdall, V., and Bottoms, G. D. (1991). Effects of dietary fiber supplementation on glycemic control in dogs with alloxan-induced diabetes-mellitus. Am J Vet Res. 52: 2060-2066
59. Nelson, R. W., Duesberg, C. A., Ford, S. L., Feldman, E. C., Davenport, D. J., Kiernan, C. and Neal, L. (1998). Effect of dietary insoluble fiber on control of glycemia in dogs with naturally acquired diabetes mellitus. J Am VetMed Assoc. 212: 380-386.
60. Nelson, R. W., Scott-Moncrieff, J. C., Feldman, E. C., Vries-Concannon, S. E., Kass, P. H., Davenport, D. J., Kiernan, C. T., and Neal, L. A. (2000). Effect of dietary insoluble fiber on control of glycemia in cats with naturally acquired diabetes mellitus. J Am Vet Med Assoc. 216: 1082-088.
61. Nguyen, P., Dumon, H., Buttin, P., Martin, L., and Gouro, A. S. (1994). Composition of meal influences changes in postprandial incremental glucose and insulin in healthy dogs. J Nutr. 124: 2707S-2711S.
62. Nguyen, P. G., Dumon, H. J., Siliart, B. S., Martin, L. J., Sergheraert, R., and Biourge, V. C. (2004a). Effects of dietary fat and energy on body weight and composition after gonadectomy in cats. Am J Vet Res. 65: 1708-1713.
63. Nguyen, P., Leray, V., Dumon, H., Martin, L., Siliart, B., Diez, M., and Biourge, V. (2004b). High protein intake affects lean body mass but not energy expenditure in nonobese neutered cats. J Nutr. 134: 2084S-2086S.
64. Nishimune, T., Yakushiji, T., Sumimoto, T., Taguchi, S., Konishi, Y., Nakahara, S., Ichikawa, T., and Kunita, N. (1991). Glycemic response and fiber content of some foods. Am J Clin Nutr. 54: 414-419.
65. Nuttall, F. Q. (1993). Dietary fiber in the management of diabetes. Diabetes. 42:503-508.
66. O'Brien, T. D. (2002). Pathogenesis of feline diabetes mellitus. Molec Cell Endocrinol. 197: 213-219.
67. Papasouliotis, K., Sparkes, A. H., Werrett, G., Egan, K., Gruffydd-Jones, E. A., and Gruffydd-Jones, T. J. (1998). Assessment of the bacterial flora of the proximal part of the small intestine in healthy cats, and the effect of sample collection method. Am J Vet Res. 59: 48-51.
68. Pfaffmann, C. (1955). Gustatory nerve impulses in rat, cat, and rabbit. Journal of Neurophysiology. 18: 429-440.
69. Prahl, A., Guptill, L., Glickman, N.W., Tetrick, M., and Glickman, L. T. (2007). Time trends and risk factors for diabetes mellitus in cats presented to veterinary teaching hospitals. J Feline Med Surg. 9: 351-358.
70. Raben, A., Tagliabue, A., Christensen, N. J., Madsen, J., Holst, J. J., and Astrup, A. (1994). Resistant starch: The effect on postprandial glycemia, hormonal response, and satiety. Am J Clin Nutr. 60: 544-551.
71. Rand, J. S., Fleeman, L. M., Farrow, H. A., Appleton, D. J., and Lederer, R. (2004). Canine and feline diabetes mellitus: Nature or nurture? J Nutr. 134: 2072S-2080S.
72. Richard, M. J., Holck, J. T., and Beitz, D. C. (1989). Lipogenesis in liver and adipose-tissue of the domestic cat (Felis Domestica). Comp Biochem Physiol B-Biochem Molec Biol. 93: 561-564.
73. Robertson, I. D. (1999). The influence of diet and other factors on ownerperceived obesity in privately owned cats from metropolitan Perth, Western Australia. Preventive Veterinary Medicine. 40: 75-85.
74. Robertson, M. D., Currie, J. M., Morgan, L. M., Jewell, D. P., and Frayn, K. N. (2003). Prior short-term consumption of resistant starch enhances postprandial insulin sensitivity in healthy subjects. Diabetologia. 46: 659-665.
75. Rogers, Q. R., Morris, J. G., and Freedland, R. A. (1977). Lack of hepatic enzymatic adaptation to low and high levels of dietary protein in the adult cat. Enzyme. 22: 348-356.
76. Russell, K., Murgatroyd, P. R., and Batt, R. M. (2002). Net protein oxidation is adapted to dietary protein intake in domestic cats (Felis silvestris catus). J Nutr. 132: 456-460.
77. Scarlett, J. M., Donoghue, S., Saidla, J., and Wills, J. (1994). Overweight cats: Prevalence and risk-factors. Int J Obes. 18: S22-S28.
78. Silva, S. V. and Mercer, J. R. (1985). Effect of protein intake on amino acid catabolism and gluconeogenesis by isolated hepatocytes from the cat (Felis domestica). Comp Biochem Physiol B-Biochem Molec Biol. 80: 603-607.
79. Slingerland, L. I., van Haeften, T. W., Beynen, A. C., Robben, J. H., Vernooij, J. C. M., and Kooistra, H. S. (2008). Effects of dietary macronutrients on glucose disposal, β-cell function, insulin sensitivity, arterial blood pressure, and body composition in healthy cats fed for weight stasis. In: Risk Factors to Feline Diabetes Mellitus, PhD Dissertation, pp. 105-120. Slingerland, L. I., Ed., University of Utrecht, Faculty of Veterinary Medicine, Utrecht, The Netherlands.
80. Slingerland, L. I., Fazilova, V. V., Plantinga, E. A., Kooistra, H. S., and Beynen, A. C. (2009). Indoor confinement and physical inactivity rather than the proportion of dry food are risk factors in the development of feline type 2 diabetes mellitus. Vet J. 179: 247-253.
81. Sloth, C. (1992). Practical management of obesity in dogs and cats. J Small Anim Pract. 33: 178-182.
82. Sparkes, A. H., Papasouliotis, K., Sunvold, G., Werrett, G., Clarke, C., Jones, M., Gruffydd-Jones, T. J., and Reinhart, G. (1998). Bacterial flora in the duodenum of healthy cats, and effect of dietary supplementation with fructooligosaccharides. Am J Vet Res. 59: 431-435.
83. Sunvold, G. D., Titgemeyer, E. C., Bourquin, L. D., Fahey, G. C., Jr., and Reinhart, G. A. (1994). Fermentability of selected fibrous substrates by cat fecal microflora. J Nutr. 124: 2721S-2722S.
84. Sunvold, G. D., Fahey, G. C., Merchen, N. R., Bourquin, L. D., Titgemeyer, E. C., Bauer, L. L., and Reinhart, G. A. (1995). Dietary fiber for cats: In vitro fermentation of selected fiber sources by cat fecal inoculum and in vivo utilization of diets containing selected fiber sources and their blends. J Anim Sci. 73: 2329-2339.
85. Sunvold, G. D., Hussein, H. S., Fahey, G. C., Jr., Merchen, N. R., and Reinhart, G. A. (1995). In vitro fermentation of cellulose, beet pulp, citrus pulp, and citrus pectin using fecal inoculum from cats, dogs, horses, humans, and pigs and ruminal fluid from cattle. J Anim Sci. 73: 3639-3648.
86. Sunvold, G. D., Fahey, G. C., Merchen, N. R., and Reinhart, G. A. (1995). In vitro fermentation of selected fibrous substrates by dog and cat fecal inoculum: Influence of diet composition on substrate organic-matter disappearance and short-chain fatty acid production. J Anim Sci. 73: 1110-1122.
87. Tanaka, A., Inoue, A., Takeguchi, A., Washizu, T., Bonkobara, M., and Arai, T. (2005). Comparison of expression of glucokinase gene and activities of enzymes related to glucose metabolism in livers between dog and cat. Vet Res Commun. 29: 477-485.
88. Thiess, S., Becskei, C., Tomsa, K., Lutz, T. A., and Wanner, M. (2004). Effects of high carbohydrate and high fat diet on plasma metabolite levels and on IV glucose tolerance test in intact and neutered mate cats. J Feline Med Surg. 6: 207-218.
89. Verbrugghe, A., Hesta, M., Van Weyenberg, S., Papadopoulos, G. A., Gommeren, K., Daminet, S., Bosmans, T., Polis, I., Buyse, J., and Janssens, G. P. J. (2010). The glucose and insulin response to iso-energetic reduction of dietary energy sources in a true carnivore: The domestic cat (Felis catus). Br J Nutr. 104: 214-221.
90. Verbrugghe, A., Hesta, M., Gommeren, K., Daminet, S., Wuyts, B., Buyse, J., and Janssens, G. P. (2009). Oligofructose and inulin modulate glucose and amino acid metabolism through propionate production in normal-weight and obese cats. Br J Nutr. 102: 694-702.
91. Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, J. J., Buyse, J., Wuyts, B., and Janssens, G. P. J. (2009). Colonic propionate might acts as gluconeogenic substrate in normal weight and obese cats, without affecting glucose tolerance. In: Nutritional Modulation of Carbohydrate Metabolism in Domestic Cats (Felis catus), pp. 65-83. Verbrugghe,A. Ed.,Ghent University, Faculty of Veterinary Medicine, Ghent, Belgium.
92. Vinuela, E., Salas, M., and Sols, A. (1963). Glucokinase and hexokinase in liver in relation to glycogen synthesis. J Biol Chem. 238: 1175-1177.
93. Washizu, T., Tanaka, A., Sako, T., Washizu, M., andArai, T. (1999). Comparison of the activities of enzymes related to glycolysis and gluconeogenesis in the liver of dogs and cats. Res Vet Sci. 67: 205-206.
94. White, T. D. and Boudreau, J. C. (1975). Taste preferences of cat for neurophysiologically active compounds. Physiological Psychology. 3: 405-410.
95. Wolever, T. M. S., Jenkins, D. J. A., Jenkins, A. L., and Josse, R. G. (1991). The glycemic index - Methodology and clinical implications. Am J Clin Nutr. 54: 846-854.
96. Wolffram, S., Eggenberger, E., and Scharrer, E. (1989). Kinetics of D-glucose transport across the intestinal brush-border membrane of the cat. Comp Biochem Physiol A-Physiol. 94: 111-115.
97. Wood, H. O. (1944). The surface area of the intestinal mucosa in the rat and in the cat. J Anat. 78: 103-105.
98. Zoran, D. L. (2002). The carnivore connection to nutrition in cats. J AmVetMed Assoc. 221: 1559-1567.