Advances in targeting the Hedgehog signaling pathway in cancer therapy

Expert Opinion on Therapeutic Targets

Volumn 16, Issue 2, 2012, Pages 151-156

  Kiesslich, Tobias ^a   Neureiter, Daniel ^a  

^a PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

Combinatory drug development; Drug resistance; Hedgehog pathway; Targeted cancer therapy

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; BMS 833923; CYCLOPAMINE; GANT 58; GANT 61; IPI 926; ITRACONAZOLE; KI 67 ANTIGEN; LEQ 506; MICRORNA; NVP LDE 225; PF 04449913; PROTEIN P53; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TAK 441; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI; TRANSCRIPTION FACTOR SUFU; UNCLASSIFIED DRUG; VISMODEGIB;

ANTINEOPLASTIC ACTIVITY; ASTROCYTE; BASAL CELL CARCINOMA; BASAL CELL NEVUS SYNDROME; CANCER INHIBITION; CANCER RESISTANCE; CARCINOGENESIS; DNA METHYLATION; DRUG EFFICACY; ENDOTHELIUM CELL; FIBROBLAST; GAIN OF FUNCTION MUTATION; HISTONE ACETYLATION; HUMAN; LOSS OF FUNCTION MUTATION; MEDULLOBLASTOMA; METASTASIS; METASTATIC MEDULLOBLASTOMA; MOLECULAR INTERACTION; MOLECULARLY TARGETED THERAPY; POINT MUTATION; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; TUMOR GROWTH; UPREGULATION;

ANTINEOPLASTIC AGENTS; HEDGEHOG PROTEINS; HUMANS; NEOPLASMS; SIGNAL TRANSDUCTION;

EID: 84857380555     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2012.652948     Document Type: Review

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