AlCl 3 induced (hetero)arylation of 2,3-dichloroquinoxaline: A one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 5, 2012, Pages 1711-1722

  Kumar, K Shiva ^a   Rambabu, D ^a,b   Sandra, Sandhya ^a   Kapavarapu, Ravikumar ^a   Krishna, G Rama ^c   Basaveswara Rao, M V ^d   Chatti, Kiranam ^a   Reddy, C Malla ^c   Misra, Parimal ^a   Pal, Manojit ^a  

^a INSTITUTE OF LIFE SCIENCES   (India)

^b K L UNIVERSITY   (India)

^c INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH KOLKATA   (India)

^d KRISHNA UNIVERSITY   (India)

Author keywords

AlCl 3; Chorismate mutase; Indole; Quinoxalines; X ray

Indexed keywords

1 (3 CHLOROQUINOXALIN 2 YL)NAPHTHALEN 2 OL; 1 [3 (5 BROMO 1H INDOL 3 YL)QUINOXALIN 2 YL]NAPHTHALEN 2 OL; 1 [3 (5 CHLORO 1H INDOL 3 YL)QUINOXALIN 2 YL]NAPHTHALEN 2 OL; 2 (1H INDOL 3 YL) 3 (6 METHOXY 1H INDOL 3 YL)QUINOXALINE; 2 (3 CHLOROQUINOXALIN 2 YL)NAPHTHALEN 1 OL; 2 (3,3 DIMETHYLBUT 1 YNYL) 3 (1 METHYL 1H INDOL 3 YL)QUINOXALINE; 2 (5 BROMO 1H INDOL 3 YL) 3 (1H INDOL 3 YL)QUINOXALINE; 2 (5 BROMO 1H INDOL 3 YL) 3 CHLOROQUINOXALINE; 2 CHLORO 3 (1 METHYL 1H INDOL 3 YL)QUINOXALINE; 2 CHLORO 3 (1H INDOL 3 YL)QUINOXALINE; 2 CHLORO 3 (5 CHLORO 1H INDOL 3 YL)QUINOXALINE; 2 CHLORO 3 (5 METHOXY 1H INDOL 3 YL)QUINOXALINE; 2 CHLORO 3 (5,6 DIFLUORO 1H INDOL 3 YL)QUINOXALINE; 2 CHLORO 3 (6 METHOXY 1H INDOL 3 YL)QUINOXALINE; 2,3 BIS(1 METHYL 1H INDOL 3 YL)QUINOXALINE; 2,3 DI(1H INDOL 3 YL)QUINOXALINE; 2,3 DICHLOROQUINOXALINE; 4 (3 CHLOROQUINOXALIN 2 YL)BENZENE 1,3 DIOL; 4 [3 (5 BROMO 1H INDOL 3 YL)QUINOXALIN 2 YL]BENZENE 1,3 DIOL; ALUMINUM CHLORIDE; CHORISMATE MUTASE; QUINOXALINE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; ALUMINUM DERIVATIVE; CHLORIDE;

ANTIBACTERIAL ACTIVITY; ARTICLE; ARYLATION; BACTERIAL GENE; CHEMICAL BINDING; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; MOLECULAR DOCKING; MTCM GENE; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; X RAY DIFFRACTION; CHEMICAL STRUCTURE; CHEMISTRY; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ALUMINUM COMPOUNDS; ANTITUBERCULAR AGENTS; CHLORIDES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; QUINOXALINES;

EID: 84857369422     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.01.012     Document Type: Article

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