Synthesis and biological evaluation of novel 4-(hetero) aryl-2-piperazino quinazolines as anti-leishmanial and anti-proliferative agents

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 9, 2009, Pages 2542-2545

  Kumar, Shailesh ^a   Shakya, Nishi ^a   Gupta, Suman ^a   Sarkar, Jayanta ^a   Sahu, Devi Prasad ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

2,4 Disubstituted quinazolines; Antileishmanial agents; Antiproliferative agents; Bis heteroaryls

Indexed keywords

ANTILEISHMANIAL AGENT; PENTAMIDINE; QUINAZOLINE DERIVATIVE; STIBOGLUCONATE SODIUM;

AMASTIGOTE; ANTINEOPLASTIC ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LEISHMANIA DONOVANI; MAMMAL CELL; NONHUMAN; PROMASTIGOTE;

ANIMALS; ANTIMONY SODIUM GLUCONATE; CELL LINE; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HUMANS; INHIBITORY CONCENTRATION 50; LEISHMANIA DONOVANI; MODELS, CHEMICAL; PENTAMIDINE; QUINAZOLINES; TRYPANOCIDAL AGENTS;

LEISHMANIA DONOVANI; MAMMALIA;

EID: 64249090421     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.03.020     Document Type: Article

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