Nerve growth factor derived from bronchial epithelium after chronic mite antigen exposure contributes to airway hyperresponsiveness by inducing hyperinnervation, and is inhibited by in vivo siRNA

Clinical and Experimental Allergy

Volumn 42, Issue 3, 2012, Pages 460-470

  Ogawa, H ^a   Azuma, M ^a   Uehara, H ^a   Takahashi, T ^a   Nishioka, Y ^a   Sone, S ^a   Izumi, K ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Airway hyperresponsiveness; Bronchial epithelium; Hyperinnervation; Nerve growth factor; Substance P

Indexed keywords

HOUSE DUST ALLERGEN; NERVE GROWTH FACTOR; SMALL INTERFERING RNA;

AIRWAY HYPERRESPONSIVENESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS MUCOSA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DERMATOPHAGOIDES PTERONYSSINUS; DISEASE EXACERBATION; FEMALE; HISTOPATHOLOGY; IN VIVO STUDY; INNERVATION; LUNG ALVEOLUS EPITHELIUM; LUNG HOMOGENATE; LUNG LAVAGE; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE;

ANIMALS; ANTIGENS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DERMATOPHAGOIDES PTERONYSSINUS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCKDOWN TECHNIQUES; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; NERVE GROWTH FACTOR; RESPIRATORY MUCOSA; RNA, SMALL INTERFERING;

EID: 84857361327     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2011.03918.x     Document Type: Article

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