The antipsychotic drug loxapine is an opener of the sodium- activated potassium channel slack (Slo2.2)

Journal of Pharmacology and Experimental Therapeutics

Volumn 340, Issue 3, 2012, Pages 706-715

  Biton, Bruno ^a   Sethuramanujam, S ^b   Picchione, Kelly E ^b   Bhattacharjee, A ^b   Khessibi, N ^a   Chesney, F ^a   Lanneau, C ^a   Curet, O ^a   Avenet, P ^a  

^a SANOFI   (France)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXAPINE; CLOZAPINE; LOXAPINE; NICLOSAMIDE; OLANZAPINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL SLO2.2; QUETIAPINE; RECOMBINANT PROTEIN; RILUZOLE; RUBIDIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; EMBRYO; FEMALE; HUMAN; HUMAN CELL; NERVE CONDUCTION; NERVE EXCITABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY CELL; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; SPINAL GANGLION;

ACTION POTENTIALS; ANIMALS; ANTIPSYCHOTIC AGENTS; CHO CELLS; CRICETINAE; CRICETULUS; GANGLIA, SPINAL; LOXAPINE; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; RILUZOLE; RUBIDIUM;

EID: 84857328420     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.184622     Document Type: Article

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