Pharmacological activation and inhibition of Slack (Slo2.2) channels

Neuropharmacology

Volumn 51, Issue 4, 2006, Pages 896-906

  Yang, Bo ^a   Gribkoff, Valentin K ^b   Pan, Jennifer ^b   Damagnez, Veronique ^b   Dworetzky, Steven I ^c   Boissard, Christopher G ^c   Bhattacharjee, Arin ^a   Yan, Yangyang ^a   Sigworth, Fred J ^a   Kaczmarek, Leonard K ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Scion Pharmaceuticals Inc   (United States)

^c BRISTOL MYERS SQUIBB   (United States)

Author keywords

Electrophysiology; Potassium channels; Slack; Sodium activated channels

Indexed keywords

BEPRIDIL; BITHIONOL; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; QUINIDINE; SEQUENCE LIKE A CALCIUM ACTIVATED POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ELECTROPHYSIOLOGY; EMBRYO; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS LAEVIS;

ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; BEPRIDIL; BITHIONOL; CALCIUM CHANNEL BLOCKERS; CELL LINE, TRANSFORMED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; QUINIDINE; TRANSFECTION; XENOPUS;

EID: 33747836278     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.06.003     Document Type: Article

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