메뉴 건너뛰기




Volumn 159, Issue 3, 2012, Pages 182-189

Altered angiogenic balance in keloids: A key to therapeutic intervention

Author keywords

cDNA; complementary DNA; ECM; ELISA; enzyme linked immunosorbent assay; extracellular matrix; IgG; immunoglobulin G; matrix metalloprotease; MMP; PCR; polymerase chain reaction; SD; SDS; SDS PAGE; serum vascular endothelial growth factor; sodium dodecyl sulfate; sodium dodecyl sulfate polyacrylamide gel electrophoresis; standard deviation; sVEGF; TIMP; tissue inhibitor of matrix metalloprotease; vascular endothelial growth factor; VEGF

Indexed keywords

BETA ACTIN; ENDOSTATIN; VASCULOTROPIN;

EID: 84857264194     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2011.10.002     Document Type: Article
Times cited : (44)

References (32)
  • 2
    • 20444427635 scopus 로고    scopus 로고
    • Endostatin: The logic of antiangiogenic therapy
    • DOI 10.1016/j.drup.2005.03.001, PII S136876460500021X
    • A. Abdollahi, L. Hlatky, and P.E. Huber Endostatin: the logic of antiangiogenic therapy Drug Resist Updat 8 2005 59 74 (Pubitemid 40797957)
    • (2005) Drug Resistance Updates , vol.8 , Issue.1-2 , pp. 59-74
    • Abdollahi, A.1    Hlatky, L.2    Huber, P.E.3
  • 3
    • 0034575632 scopus 로고    scopus 로고
    • The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing
    • W. Bloch, K. Huggel, and T. Sasaki The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing FASEB J 14 2000 2373 2376
    • (2000) FASEB J , vol.14 , pp. 2373-2376
    • Bloch, W.1    Huggel, K.2    Sasaki, T.3
  • 4
    • 48149090563 scopus 로고    scopus 로고
    • Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing
    • L. Seppinen, R. Sormunen, and Y. Soini Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing Matrix Biol 27 2008 535 546
    • (2008) Matrix Biol , vol.27 , pp. 535-546
    • Seppinen, L.1    Sormunen, R.2    Soini, Y.3
  • 5
    • 33845450616 scopus 로고    scopus 로고
    • The keloid phenomenon: Progress toward a solution
    • DOI 10.1002/ca.20374
    • L. Louw The keloid phenomenon: progress toward a solution Clin Anat 20 2007 3 14 (Pubitemid 44893986)
    • (2007) Clinical Anatomy , vol.20 , Issue.1 , pp. 3-14
    • Louw, L.1
  • 6
    • 0026843757 scopus 로고
    • The microvessels in hypertrophic scars, keloids and related lesions: A review
    • C.W. Kischer The microvessels in hypertrophic scars, keloids and related lesions: a review J Submicrosc Cytol Pathol 24 1992 281 296
    • (1992) J Submicrosc Cytol Pathol , vol.24 , pp. 281-296
    • Kischer, C.W.1
  • 7
    • 28344454083 scopus 로고    scopus 로고
    • Hypoxia-induced HIF-1 α accumulation is augmented in a co-culture of keloid fibroblasts and human mast cells: Involvement of ERK1/2 and PI-3K/Akt
    • DOI 10.1016/j.yexcr.2005.10.006, PII S0014482705004623
    • Q. Zhang, C.K. Oh, and D.V. Messadi Hypoxia-induced HIF-1 alpha accumulation is augmented in a co-culture of keloid fibroblasts and human mast cells: involvement of ERK1/2 and PI-3K/Akt Exp Cell Res 312 2006 145 155 (Pubitemid 41721177)
    • (2006) Experimental Cell Research , vol.312 , Issue.2 , pp. 145-155
    • Zhang, Q.1    Oh, C.K.2    Messadi, D.V.3    Duong, H.S.4    Kelly, A.P.5    Soo, C.6    Wang, L.7    Le, A.D.8
  • 9
    • 77949905452 scopus 로고    scopus 로고
    • Molecular dissection of abnormal wound healing processes resulting in keloid disease
    • B. Shih, E. Garside, D.A. McGrouther, and A. Bayat Molecular dissection of abnormal wound healing processes resulting in keloid disease Wound Repair Regen 18 2010 139 153
    • (2010) Wound Repair Regen , vol.18 , pp. 139-153
    • Shih, B.1    Garside, E.2    McGrouther, D.A.3    Bayat, A.4
  • 11
    • 0029948302 scopus 로고    scopus 로고
    • Apoptosis, necrosis, and proliferation: Possible implications in the etiology of keloids
    • I. Appleton, N.J. Brown, and D.A. Willoughby Apoptosis, necrosis, and proliferation: possible implications in the etiology of keloids Am J Pathol 149 1996 1441 1447 (Pubitemid 26363950)
    • (1996) American Journal of Pathology , vol.149 , Issue.5 , pp. 1441-1447
    • Appleton, I.1    Brown, N.J.2    Willoughby, D.A.3
  • 12
    • 0032891017 scopus 로고    scopus 로고
    • Hypoxia upregulates VEGF production in keloid fibroblasts
    • D.S. Steinbrech, B.J. Mehrara, and D. Chau Hypoxia upregulates VEGF production in keloid fibroblasts Ann Plast Surg 42 1999 514 519
    • (1999) Ann Plast Surg , vol.42 , pp. 514-519
    • Steinbrech, D.S.1    Mehrara, B.J.2    Chau, D.3
  • 14
    • 33846258102 scopus 로고    scopus 로고
    • Epithelial-mesenchymal interactions in keloid pathologenesis modulate vascular endothelial growth factor expression and secretion
    • DOI 10.1002/path.2081
    • C.T. Ong, Y.T. Khoo, and E.K. Tan Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion J Pathol 211 2007 95 108 (Pubitemid 46092034)
    • (2007) Journal of Pathology , vol.211 , Issue.1 , pp. 95-108
    • Ong, C.T.1    Khoo, Y.T.2    Tan, E.K.3    Mukhopadhyay, A.4    Do, D.V.5    Han, H.C.6    Lim, I.J.7    Phan, T.T.8
  • 15
    • 0035871306 scopus 로고    scopus 로고
    • Serum endostatin levels are elevated in patients with soft tissue sarcoma
    • DOI 10.1002/1097-0142(20010415)91:8<1525::AID-CNCR1161>3.0.CO;2-P
    • A.L. Feldman, H. Pak, J.C. Yang, H.R. Alexander Jr., and S.K. Libutti Serum endostatin levels are elevated in patients with soft tissue sarcoma Cancer 91 2001 1525 1529 (Pubitemid 32319264)
    • (2001) Cancer , vol.91 , Issue.8 , pp. 1525-1529
    • Feldman, A.L.1    Pak, H.2    Yang, J.C.3    Richard Alexander Jr., H.4    Libutti, S.K.5
  • 16
    • 25644436232 scopus 로고    scopus 로고
    • Correlation of endostatin and tissue inhibitor of metalloproteinases 2 (TIMP2) serum levels with cardiovascular involvement in systemic sclerosis patients
    • DOI 10.1155/MI.2005.144, PII S0962935105501145
    • B. Dziankowska-Bartkowiak, E. Waszczykowska, A. Zalewska, and A. Sysa-Jedrzejowska Correlation of endostatin and tissue inhibitor of metalloproteinases 2 (TIMP2) serum levels with cardiovascular involvement in systemic sclerosis patients Mediators Inflamm 2005 2005 144 149 (Pubitemid 41381522)
    • (2005) Mediators of Inflammation , vol.2005 , Issue.3 , pp. 144-149
    • Dziankowska-Bartkowiak, B.1    Waszczykowska, E.2    Zalewska, A.3    Sysa-Jedrzejowska, A.4
  • 17
    • 14744297361 scopus 로고    scopus 로고
    • Imbalance in the production between vascular endothelial growth factor and endostatin in Kawasaki disease
    • DOI 10.1111/j.1365-2249.2005.02714.x
    • S. Takeshita, Y. Kawamura, H. Takabayashi, N. Yoshida, and S. Nonoyama Imbalance in the production between vascular endothelial growth factor and endostatin in Kawasaki disease Clin Exp Immunol 139 2005 575 579 (Pubitemid 40333270)
    • (2005) Clinical and Experimental Immunology , vol.139 , Issue.3 , pp. 575-579
    • Takeshita, S.1    Kawamura, Y.2    Takabayashi, H.3    Yoshida, N.4    Nonoyama, S.5
  • 18
    • 78049291026 scopus 로고    scopus 로고
    • Clinical significance of serum vascular endothelial growth factor, endostatin and leptin levels in children with lymphoma
    • F.V. Okur, C. Karadeniz, and M. Buyukpamukcu Clinical significance of serum vascular endothelial growth factor, endostatin and leptin levels in children with lymphoma Pediatr Blood Cancer 55 2010 1272 1277
    • (2010) Pediatr Blood Cancer , vol.55 , pp. 1272-1277
    • Okur, F.V.1    Karadeniz, C.2    Buyukpamukcu, M.3
  • 19
    • 79952104610 scopus 로고    scopus 로고
    • The multiple functions of collagen XVIII in development and disease
    • L. Seppinen, and T. Pihlajaniemi The multiple functions of collagen XVIII in development and disease Matrix Biol 30 2011 83 92
    • (2011) Matrix Biol , vol.30 , pp. 83-92
    • Seppinen, L.1    Pihlajaniemi, T.2
  • 22
    • 63149142772 scopus 로고    scopus 로고
    • Matrix metalloproteinase - 2 and - 9 activities in human keloids, hypertrophic and atrophic scars: A pilot study
    • S. Tanriverdi-Akhisaroglu, A. Menderes, and G. Oktay Matrix metalloproteinase - 2 and - 9 activities in human keloids, hypertrophic and atrophic scars: a pilot study Cell Biochem Funct 27 2009 81 87
    • (2009) Cell Biochem Funct , vol.27 , pp. 81-87
    • Tanriverdi-Akhisaroglu, S.1    Menderes, A.2    Oktay, G.3
  • 24
    • 0037157106 scopus 로고    scopus 로고
    • Endostatin binds to the catalytic domain of matrix metalloproteinase-2
    • S.J. Lee, J.W. Jang, and Y.M. Kim Endostatin binds to the catalytic domain of matrix metalloproteinase-2 FEBS Lett 519 2002 147 152
    • (2002) FEBS Lett , vol.519 , pp. 147-152
    • Lee, S.J.1    Jang, J.W.2    Kim, Y.M.3
  • 27
    • 33746513742 scopus 로고    scopus 로고
    • Upregulation of the Wnt/β-catenin pathway induced by transforming growth factor-β in hypertrophic scars and keloids
    • DOI 10.2340/00015555-0101
    • M. Sato Upregulation of the Wnt/beta-catenin pathway induced by transforming growth factor-beta in hypertrophic scars and keloids Acta Derm Venereol 86 2006 300 307 (Pubitemid 44133374)
    • (2006) Acta Dermato-Venereologica , vol.86 , Issue.4 , pp. 300-307
    • Sato, M.1
  • 28
    • 2142657200 scopus 로고    scopus 로고
    • Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts
    • Y. Wu, Q. Zhang, and D.K. Ann Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts Am J Physiol Cell Physiol 286 2004 C905 C912
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Wu, Y.1    Zhang, Q.2    Ann, D.K.3
  • 29
    • 0024508608 scopus 로고
    • Fibronectin is overproduced by keloid fibroblasts during abnormal wound healing
    • M. Babu, R. Diegelmann, and N. Oliver Fibronectin is overproduced by keloid fibroblasts during abnormal wound healing Mol Cell Biol 9 1989 1642 1650 (Pubitemid 19095205)
    • (1989) Molecular and Cellular Biology , vol.9 , Issue.4 , pp. 1642-1650
    • Babu, M.1    Diegelmann, R.2    Oliver, N.3
  • 30
    • 33744524790 scopus 로고    scopus 로고
    • Nitric oxide produced by iNOS is associated with collagen synthesis in keloid scar formation
    • DOI 10.1016/j.niox.2006.01.006, PII S1089860306000243
    • Y.C. Hsu, M. Hsiao, L.F. Wang, Y.W. Chien, and W.R. Lee Nitric oxide produced by iNOS is associated with collagen synthesis in keloid scar formation Nitric Oxide 14 2006 327 334 (Pubitemid 43816315)
    • (2006) Nitric Oxide - Biology and Chemistry , vol.14 , Issue.4 , pp. 327-334
    • Hsu, Y.-C.1    Hsiao, M.2    Wang, L.-F.3    Chien, Y.W.4    Lee, W.-R.5
  • 31
    • 42149158926 scopus 로고    scopus 로고
    • Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways
    • DOI 10.1038/sj.jid.5701149, PII 5701149
    • J.C. Smith, B.E. Boone, S.R. Opalenik, S.M. Williams, and S.B. Russell Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways J Invest Dermatol 128 2008 1298 1310 (Pubitemid 351543197)
    • (2008) Journal of Investigative Dermatology , vol.128 , Issue.5 , pp. 1298-1310
    • Smith, J.C.1    Boone, B.E.2    Opalenik, S.R.3    Williams, S.M.4    Russell, S.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.