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Volumn 128, Issue 3, 2008, Pages 702-709

Human skin keloid fibroblasts display bioenergetics of cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; COBALT CHLORIDE; DEFEROXAMINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEXOKINASE; HYPOXIA INDUCIBLE FACTOR 1; LACTATE DEHYDROGENASE; LACTIC ACID; REACTIVE OXYGEN METABOLITE;

EID: 39149095601     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5701107     Document Type: Article
Times cited : (142)

References (50)
  • 1
    • 0033179481 scopus 로고    scopus 로고
    • Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes
    • Ainscow EK, Brand MD (1999) Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. Eur J Biochem 263:671-85
    • (1999) Eur J Biochem , vol.263 , pp. 671-685
    • Ainscow, E.K.1    Brand, M.D.2
  • 2
    • 0035661664 scopus 로고    scopus 로고
    • Albina JE, Mastrofrancesco B, Vessella JA, Louis CA, Henry WL Jr, Reichner JS (2001) HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha. Am J Physiol Cell Physiol 281:C1971-7
    • Albina JE, Mastrofrancesco B, Vessella JA, Louis CA, Henry WL Jr, Reichner JS (2001) HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha. Am J Physiol Cell Physiol 281:C1971-7
  • 3
    • 0036328867 scopus 로고    scopus 로고
    • 2 generation in isolated mitochondria
    • 2 generation in isolated mitochondria. J Bioenerg Biomembr 34:227-33
    • (2002) J Bioenerg Biomembr , vol.34 , pp. 227-233
    • Barja, G.1
  • 4
    • 0027172514 scopus 로고
    • Characterization of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-Kd nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells
    • Beck I, Weinmann R, Caro J (1993) Characterization of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-Kd nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells. Blood 82:704-11
    • (1993) Blood , vol.82 , pp. 704-711
    • Beck, I.1    Weinmann, R.2    Caro, J.3
  • 5
    • 0022415127 scopus 로고
    • Transcutaneous oxygen tension as an index of maturity in hypertrophic scars treated by compression
    • Berry RB, Tan OT, Cooke ED, Gaylarde PM, Bowcock SA, Lamberty BG et al. (1985) Transcutaneous oxygen tension as an index of maturity in hypertrophic scars treated by compression. Br J Plast Surg 38:163-73
    • (1985) Br J Plast Surg , vol.38 , pp. 163-173
    • Berry, R.B.1    Tan, O.T.2    Cooke, E.D.3    Gaylarde, P.M.4    Bowcock, S.A.5    Lamberty, B.G.6
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-54
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0030945198 scopus 로고    scopus 로고
    • Aerobic glycolysis by proliferating cells: A protective strategy against reactive oxygen species
    • Brand KA, Hermfisse U (1997) Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species. FASEB J 11:388-95
    • (1997) FASEB J , vol.11 , pp. 388-395
    • Brand, K.A.1    Hermfisse, U.2
  • 9
    • 0000381877 scopus 로고
    • Glycolysis, tricarboxylic acid and related enzymes in brain
    • Boulton A, Baker G, Butterworth RF eds New Jersey: Humana Press
    • Clark JB, Lai CK (1989) Glycolysis, tricarboxylic acid and related enzymes in brain. In: Neuromethods (Boulton A, Baker G, Butterworth RF eds) vol. 11. New Jersey: Humana Press, 233-81
    • (1989) Neuromethods , vol.11 , pp. 233-281
    • Clark, J.B.1    Lai, C.K.2
  • 10
    • 0035163491 scopus 로고    scopus 로고
    • The role of nitric acid in the formation of keloid and hypertrophic lesions
    • Cobbold CA (2001) The role of nitric acid in the formation of keloid and hypertrophic lesions. Med Hypotheses 57:497-502
    • (2001) Med Hypotheses , vol.57 , pp. 497-502
    • Cobbold, C.A.1
  • 11
    • 0018349618 scopus 로고
    • Growth kinetics and collagen synthesis of normal skin, normal scar and keloid fibroblasts in vitro
    • Diegelmann RF, Cohen IK, McCoy BJ (1979) Growth kinetics and collagen synthesis of normal skin, normal scar and keloid fibroblasts in vitro. J Cell Physiol 98:341-6
    • (1979) J Cell Physiol , vol.98 , pp. 341-346
    • Diegelmann, R.F.1    Cohen, I.K.2    McCoy, B.J.3
  • 12
    • 0028843411 scopus 로고
    • Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents
    • Gleadle JM, Ebert BL, Firth JD, Ratcliffe PJ (1995) Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents. Am J Physiol 268:C1362-8
    • (1995) Am J Physiol , vol.268
    • Gleadle, J.M.1    Ebert, B.L.2    Firth, J.D.3    Ratcliffe, P.J.4
  • 14
    • 0033962899 scopus 로고    scopus 로고
    • Early wound healing exhibits cytokine surge without evidence of hypoxia
    • Haroon ZA, Raleigh JA, Greenberg CS, Dewhirst MW (2000) Early wound healing exhibits cytokine surge without evidence of hypoxia. Ann Surg 231:137-47
    • (2000) Ann Surg , vol.231 , pp. 137-147
    • Haroon, Z.A.1    Raleigh, J.A.2    Greenberg, C.S.3    Dewhirst, M.W.4
  • 15
    • 0035027711 scopus 로고    scopus 로고
    • Hypertrophic scars and keloids
    • Haverstock BD (2001) Hypertrophic scars and keloids. Clin Podiatr Med Surg 18:147-59
    • (2001) Clin Podiatr Med Surg , vol.18 , pp. 147-159
    • Haverstock, B.D.1
  • 16
    • 0015011902 scopus 로고
    • Enzyme activities in hypertrophic scars and keloids
    • Hoopes JE, Su CT, Im MJ (1971) Enzyme activities in hypertrophic scars and keloids. Plast Reconstr Surg 47:132-7
    • (1971) Plast Reconstr Surg , vol.47 , pp. 132-137
    • Hoopes, J.E.1    Su, C.T.2    Im, M.J.3
  • 17
    • 0024519213 scopus 로고
    • Two kinetic methods to study the regulation of mammalian hexokinases
    • Jenkins WT, Thompson CC (1989) Two kinetic methods to study the regulation of mammalian hexokinases. Anal Biochem 177:396-401
    • (1989) Anal Biochem , vol.177 , pp. 396-401
    • Jenkins, W.T.1    Thompson, C.C.2
  • 18
    • 0347359161 scopus 로고    scopus 로고
    • Modification of glycolysis affects cell sensitivity to apoptosis induced by oxidative stress and mediated by mitochondria
    • Jeong DW, Kim TS, Cho IT, Kim IY (2004) Modification of glycolysis affects cell sensitivity to apoptosis induced by oxidative stress and mediated by mitochondria. Biochem Biophys Res Commun 313:984-91
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 984-991
    • Jeong, D.W.1    Kim, T.S.2    Cho, I.T.3    Kim, I.Y.4
  • 21
    • 0029076629 scopus 로고
    • Oxygraphic evaluation of mitochondrial function in digitonin- permeabilized mononuclear cells and cultured skin fibroblasts of patients with chronic progressive external ophthalmoplegia
    • Kunz D, Luley C, Fritz S, Bohnensack R, Winkler K, Kunz WS et al. (1995) Oxygraphic evaluation of mitochondrial function in digitonin- permeabilized mononuclear cells and cultured skin fibroblasts of patients with chronic progressive external ophthalmoplegia. Biochem Mol Med 54:105-11
    • (1995) Biochem Mol Med , vol.54 , pp. 105-111
    • Kunz, D.1    Luley, C.2    Fritz, S.3    Bohnensack, R.4    Winkler, K.5    Kunz, W.S.6
  • 22
    • 0019059433 scopus 로고
    • P1,P5-Di(adenosine-5′) pentaphosphate(Ap5A) as an inhibitor of adenylate kinase in studies of fragmented sarcoplasmic reticulum from bullfrog skeletal muscle
    • Kurebayashi N, Kodama T, Ogawa Y (1980) P1,P5-Di(adenosine-5′) pentaphosphate(Ap5A) as an inhibitor of adenylate kinase in studies of fragmented sarcoplasmic reticulum from bullfrog skeletal muscle. J Biochem (Tokyo) 88:871-6
    • (1980) J Biochem (Tokyo) , vol.88 , pp. 871-876
    • Kurebayashi, N.1    Kodama, T.2    Ogawa, Y.3
  • 24
    • 0027461553 scopus 로고
    • Inducible operation of the erythropoietin 3′ enhancer in multiple cell lines: Evidence for a widespread oxygen-sensing mechanism
    • Maxwell PH, Pugh CW, Ratcliffe PJ (1993) Inducible operation of the erythropoietin 3′ enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism. Proc Natl Acad Sci USA 90:2423-7
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2423-2427
    • Maxwell, P.H.1    Pugh, C.W.2    Ratcliffe, P.J.3
  • 27
    • 0000415614 scopus 로고    scopus 로고
    • Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics
    • Mourant JR, Freyer JP, Hielscher AH, Eick AA, Shen D, Johnson TM (1998) Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics. Applied Optics 37:3586-93
    • (1998) Applied Optics , vol.37 , pp. 3586-3593
    • Mourant, J.R.1    Freyer, J.P.2    Hielscher, A.H.3    Eick, A.A.4    Shen, D.5    Johnson, T.M.6
  • 31
    • 0015253155 scopus 로고
    • Measurement of wound oxygen with implanted Silastic tube
    • Ninikoski J, Hunt TK (1972) Measurement of wound oxygen with implanted Silastic tube. Surgery 71:22-6
    • (1972) Surgery , vol.71 , pp. 22-26
    • Ninikoski, J.1    Hunt, T.K.2
  • 32
    • 0032532674 scopus 로고    scopus 로고
    • Mitochondrial ATP synthesis in permeabilized cells: Assessment of the ATP/O values in situ
    • Ouhabi R, Boue-Grabot M, Mazat JP (1998) Mitochondrial ATP synthesis in permeabilized cells: assessment of the ATP/O values in situ. Anal Biochem 263:169-75
    • (1998) Anal Biochem , vol.263 , pp. 169-175
    • Ouhabi, R.1    Boue-Grabot, M.2    Mazat, J.P.3
  • 33
    • 17844383964 scopus 로고    scopus 로고
    • Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements
    • Ramanathan A, Wang C, Schreiber S (2005) Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci USA 102:5992-7
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5992-5997
    • Ramanathan, A.1    Wang, C.2    Schreiber, S.3
  • 34
    • 0021345887 scopus 로고
    • Coordinate regulation of glycolysis by hypoxia in mammalian cells
    • Robin ED, Murphy BJ, Theodore J (1984) Coordinate regulation of glycolysis by hypoxia in mammalian cells. J Cell Physiol 118:287-90
    • (1984) J Cell Physiol , vol.118 , pp. 287-290
    • Robin, E.D.1    Murphy, B.J.2    Theodore, J.3
  • 35
    • 0001475111 scopus 로고
    • Intramolecular hydrogen transfer in the phosphoglucose isomerase reaction
    • Rose IA, O'Connell EL (1961) Intramolecular hydrogen transfer in the phosphoglucose isomerase reaction. J Biol Chem 236:3086-92
    • (1961) J Biol Chem , vol.236 , pp. 3086-3092
    • Rose, I.A.1    O'Connell, E.L.2
  • 36
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor 1
    • 2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 15:551-78
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 37
    • 0028068606 scopus 로고
    • Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
    • Semenza GL, Roth PH, Fang HM, Wang GL (1994) Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 269:23757-63
    • (1994) J Biol Chem , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.M.3    Wang, G.L.4
  • 39
    • 0034712939 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
    • Sutter CH, Laughner E, Semenza GL (2000) Hypoxia-inducible factor 1 alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations. Proc Natl Acad Sci USA 97:4748-53
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4748-4753
    • Sutter, C.H.1    Laughner, E.2    Semenza, G.L.3
  • 41
    • 33947726287 scopus 로고    scopus 로고
    • Intraarterial therapy with a new potent inhibitor of tumor metabolism (3-bromopyruvate): Identification of therapeutic dose and method of injection in an animal model of liver cancer
    • Vali M, Liapi E, Kowalski J, Hong K, Khwaja A, Torbenson MS et al. (2007) Intraarterial therapy with a new potent inhibitor of tumor metabolism (3-bromopyruvate): identification of therapeutic dose and method of injection in an animal model of liver cancer. Interv Radiol 18:95-101
    • (2007) Interv Radiol , vol.18 , pp. 95-101
    • Vali, M.1    Liapi, E.2    Kowalski, J.3    Hong, K.4    Khwaja, A.5    Torbenson, M.S.6
  • 42
    • 0033610865 scopus 로고    scopus 로고
    • Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types
    • Villani G, Greco M, Papa S, Attardi G (1998) Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types. J Biol Chem 273:31829-36
    • (1998) J Biol Chem , vol.273 , pp. 31829-31836
    • Villani, G.1    Greco, M.2    Papa, S.3    Attardi, G.4
  • 44
    • 0027210562 scopus 로고
    • General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
    • Wang GL, Semenza GL (1993) General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci USA 90:4304-8
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4304-4308
    • Wang, G.L.1    Semenza, G.L.2
  • 45
    • 0032820452 scopus 로고    scopus 로고
    • Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader
    • Wang H, Joseph JA (1999) Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic Biol Med 27:612-6
    • (1999) Free Radic Biol Med , vol.27 , pp. 612-616
    • Wang, H.1    Joseph, J.A.2
  • 46
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O (1956) On the origin of cancer cells. Science 123:309-14
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 47
    • 2142657200 scopus 로고    scopus 로고
    • Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts
    • Wu Y, Zhang Q, Ann DK, Akhondzadeh A, Duong HS, Messadi DV et al. (2004) Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts. Am J Physiol Cell Physiol 286:C905-12
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Wu, Y.1    Zhang, Q.2    Ann, D.K.3    Akhondzadeh, A.4    Duong, H.S.5    Messadi, D.V.6
  • 48
    • 28344454083 scopus 로고    scopus 로고
    • Hypoxia-induced HIF-1 alpha accumulation is augmented in a co-culture of keloid fibroblasts and human mast cells: Involvement of ERK1/2 and PI-3K/Akt
    • Zhang Q, Oh CK, Messadi DV, Duong HS, Kelly AP, Soo C et al. (2006) Hypoxia-induced HIF-1 alpha accumulation is augmented in a co-culture of keloid fibroblasts and human mast cells: involvement of ERK1/2 and PI-3K/Akt. Exp Cell Res 312:145-55
    • (2006) Exp Cell Res , vol.312 , pp. 145-155
    • Zhang, Q.1    Oh, C.K.2    Messadi, D.V.3    Duong, H.S.4    Kelly, A.P.5    Soo, C.6
  • 49
    • 0242406744 scopus 로고    scopus 로고
    • Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts
    • Zhang Q, Wu Y, Ann DK, Messadi DV, Tuan TL, Kelly AP et al. (2003) Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts. J Invest Dermatol 121:1005-12
    • (2003) J Invest Dermatol , vol.121 , pp. 1005-1012
    • Zhang, Q.1    Wu, Y.2    Ann, D.K.3    Messadi, D.V.4    Tuan, T.L.5    Kelly, A.P.6
  • 50
    • 5644288504 scopus 로고    scopus 로고
    • A mechanism of sulfite neurotoxicity: Direct inhibition of glutamate dehydrogenase
    • Zhang X, Vincent AS, Halliwell B, Wong KP (2004) A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenase. J Biol Chem 279:43035-45
    • (2004) J Biol Chem , vol.279 , pp. 43035-43045
    • Zhang, X.1    Vincent, A.S.2    Halliwell, B.3    Wong, K.P.4


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