Protein kinase A-dependent suppression of reactive oxygen species in transient focal ischemia in adrenomedullin-deficient mice

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 11, 2009, Pages 1769-1779

  Miyamoto, Nobukazu ^a   Tanaka, Ryota ^a,b   Shimosawa, Tatsuo ^c   Yatomi, Yutaka ^c   Fujita, Toshiro ^d   Hattori, Nobutaka ^a   Urabe, Takao ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JUNTENDO UNIVERSITY URAYASU HOSPITAL   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Adrenomedullin; Cyclic AMP; Ischemia reperfusion injury; Protein kinase A; Reactive oxygen species

Indexed keywords

ADRENOMEDULLIN; CILOSTAZOL; CYCLIC AMP DEPENDENT PROTEIN KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHODIESTERASE III INHIBITOR; PHOSPHODIESTERASE IV INHIBITOR; REACTIVE OXYGEN METABOLITE; ROLIPRAM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL ACTIVATION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; HETEROZYGOTE; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPERFUSION; SURVIVAL RATE;

ADRENOMEDULLIN; ANIMALS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HETEROZYGOTE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; ISCHEMIC ATTACK, TRANSIENT; ISOQUINOLINES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHODIESTERASE INHIBITORS; REACTIVE OXYGEN SPECIES; SULFONAMIDES; TETRAZOLES;

EID: 71949115323     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2009.92     Document Type: Article

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