-
1
-
-
56949105254
-
Pololike kinase 1 reaches beyond mitosis-cytokinesis, DNA damage response and development
-
PMID:19000759
-
Takaki T, Trenz K, Costanzo V, Petronczki M. Pololike kinase 1 reaches beyond mitosis-cytokinesis, DNA damage response and development. Curr Opin Cell Biol 2008; 20:650-60; PMID:19000759; http:// dx.doi.org/10.1016/j.ceb.2008.10. 005.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 650-660
-
-
Takaki, T.1
Trenz, K.2
Costanzo, V.3
Petronczki, M.4
-
2
-
-
43049151493
-
Polo on the Risefrom Mitotic Entry to Cytokinesis with Plk1
-
PMID:18477449
-
Petronczki M, Lénárt P, Peters JM. Polo on the Risefrom Mitotic Entry to Cytokinesis with Plk1. Dev Cell 2008; 14:646-59; PMID:18477449; http://dx.doi. org/10.1016/j.devcel.2008.04.014.
-
(2008)
Dev Cell
, vol.14
, pp. 646-659
-
-
Petronczki, M.1
Lénárt, P.2
Peters, J.M.3
-
3
-
-
79960446938
-
From Plk1 to Plk5: Functional evolution of polo-like kinases
-
PMID:21654194
-
de Cárcer G, Manning G, Malumbres M. From Plk1 to Plk5: functional evolution of polo-like kinases. Cell Cycle 2011; 10:2255-62; PMID:21654194; http:// dx.doi.org/10.4161/cc.10.14.16494.
-
(2011)
Cell Cycle
, vol.10
, pp. 2255-2262
-
-
De Cárcer, G.1
Manning, G.2
Malumbres, M.3
-
4
-
-
77954159791
-
Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway
-
PMID:20581453
-
Lee HJ, Hwang HI, Jang YJ. Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway. Cell Cycle 2010; 9:2389-98; PMID:20581453; http://dx.doi. org/10.4161/cc.9.12.11904.
-
(2010)
Cell Cycle
, vol.9
, pp. 2389-2398
-
-
Lee, H.J.1
Hwang, H.I.2
Jang, Y.J.3
-
5
-
-
22844437779
-
Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage
-
PMID:15611664
-
Tsvetkov L, Stern DF. Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage. Cell Cycle 2005; 4:166-71; PMID:15611664; http:// dx.doi.org/10.4161/cc.4.1.1348.
-
(2005)
Cell Cycle
, vol.4
, pp. 166-171
-
-
Tsvetkov, L.1
Stern, D.F.2
-
6
-
-
77955167321
-
Multifaceted polo-like kinases: Drug targets and antitargets for cancer therapy
-
PMID:20671765
-
Strebhardt K. Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy. Nat Rev Drug Discov 2010; 9:643-60; PMID:20671765; http:// dx.doi.org/10.1038/nrd3184.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 643-660
-
-
Strebhardt, K.1
-
7
-
-
62849123093
-
Polo-like kinases: Conservation and divergence in their functions and regulation
-
PMID:19305416
-
Archambault V, Glover DM. Polo-like kinases: conservation and divergence in their functions and regulation. Nat Rev Mol Cell Biol 2009; 10:265- 75; PMID:19305416; http://dx.doi.org/10.1038/ nrm2653.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 265-275
-
-
Archambault, V.1
Glover, D.M.2
-
8
-
-
13244269808
-
Polo-like kinases and oncogenesis
-
PMID:15640842
-
Eckerdt F, Yuan J, Strebhardt K. Polo-like kinases and oncogenesis. Oncogene 2005; 24:267-76; PMID:15640842; http://dx.doi.org/10.1038/ sj.onc.1208273.
-
(2005)
Oncogene
, vol.24
, pp. 267-276
-
-
Eckerdt, F.1
Yuan, J.2
Strebhardt, K.3
-
9
-
-
33645316142
-
Targeting polo-like kinase 1 for cancer therapy
-
PMID:16557283
-
Strebhardt K, Ullrich A. Targeting polo-like kinase 1 for cancer therapy. Nat Rev Cancer 2006; 6:321-30; PMID:16557283; http://dx.doi.org/10.1038/ nrc1841.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 321-330
-
-
Strebhardt, K.1
Ullrich, A.2
-
10
-
-
66149091940
-
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
-
PMID:19490893
-
Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, et al. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell 2009; 137:835- 48; PMID:19490893; http://dx.doi.org/10.1016/j. cell.2009.05.006.
-
(2009)
Cell
, vol.137
, pp. 835-848
-
-
Luo, J.1
Emanuele, M.J.2
Li, D.3
Creighton, C.J.4
Schlabach, M.R.5
Westbrook, T.F.6
-
11
-
-
78649476052
-
Shared and separate functions of polo-like kinases and aurora kinases in cancer
-
PMID:21102634
-
Lens SM, Voest EE, Medema RH. Shared and separate functions of polo-like kinases and aurora kinases in cancer. Nat Rev Cancer 2010; 10:825-41; PMID:21102634; http://dx.doi.org/10.1038/nrc2964.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 825-841
-
-
Lens, S.M.1
Voest, E.E.2
Medema, R.H.3
-
12
-
-
39149089275
-
Polo and Aurora kinases: Lessons derived from chemical biology
-
PMID:18249108
-
Taylor S, Peters JM. Polo and Aurora kinases: lessons derived from chemical biology. Curr Opin Cell Biol 2008; 20:77-84; PMID:18249108; http://dx.doi. org/10.1016/j.ceb.2007.11.008.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 77-84
-
-
Taylor, S.1
Peters, J.M.2
-
13
-
-
77953170553
-
Biological impact of freezing Plk1 in its inactive conformation in cancer cells
-
PMID:20139717
-
Keppner S, Proschak E, Kaufmann M, Strebhardt K, Schneider G, Spänkuch B. Biological impact of freezing Plk1 in its inactive conformation in cancer cells. Cell Cycle 2010; 9:761-73; PMID:20139717; http:// dx.doi.org/10.4161/cc.9.4.10644.
-
(2010)
Cell Cycle
, vol.9
, pp. 761-773
-
-
Keppner, S.1
Proschak, E.2
Kaufmann, M.3
Strebhardt, K.4
Schneider, G.5
Spänkuch, B.6
-
14
-
-
33846933218
-
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo
-
PMID:17291758
-
Steegmaier M, Hoffmann M, Baum A, Lénárt P, Petronczki M, Krssák M, et al. BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo. Curr Biol 2007; 17:316- 22; PMID:17291758; http://dx.doi.org/10.1016/j. cub.2006.12.037.
-
(2007)
Curr Biol
, vol.17
, pp. 316-322
-
-
Steegmaier, M.1
Hoffmann, M.2
Baum, A.3
Lénárt, P.4
Petronczki, M.5
Krssák, M.6
-
15
-
-
33846931644
-
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1
-
PMID:17291761
-
Lénárt P, Petronczki M, Steegmaier M, Di Fiore B, Lipp JJ, Hoffmann M, et al. The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1. Curr Biol 2007; 17:304- 15; PMID:17291761; http://dx.doi.org/10.1016/j. cub.2006.12.046.
-
(2007)
Curr Biol
, vol.17
, pp. 304-315
-
-
Lénárt, P.1
Petronczki, M.2
Steegmaier, M.3
Di Fiore, B.4
Lipp, J.J.5
Hoffmann, M.6
-
16
-
-
65649105075
-
BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity
-
PMID:19383823
-
Rudolph D, Steegmaier M, Hoffmann M, Grauert M, Baum A, Quant J, et al. BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity. Clin Cancer Res 2009; 15:3094-102; PMID:19383823; http://dx.doi. org/10.1158/1078-0432.CCR-08-2445.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3094-3102
-
-
Rudolph, D.1
Steegmaier, M.2
Hoffmann, M.3
Grauert, M.4
Baum, A.5
Quant, J.6
-
17
-
-
34948818671
-
Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis
-
PMID:17671160
-
Santamaria A, Neef R, Eberspächer U, Eis K, Husemann M, Mumberg D, et al. Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Mol Biol Cell 2007; 18:4024-36; PMID:17671160; http:// dx.doi.org/10.1091/mbc.E07-05-0517.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 4024-4036
-
-
Santamaria, A.1
Neef, R.2
Eberspächer, U.3
Eis, K.4
Husemann, M.5
Mumberg, D.6
-
18
-
-
33847403132
-
In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1
-
PMID:17267659
-
Lansing TJ, McConnell RT, Duckett DR, Spehar GM, Knick VB, Hassler DF, et al. In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1. Mol Cancer Ther 2007; 6:450-9; PMID:17267659; http://dx.doi.org/10.1158/1535-7163.MCT-06-0543.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 450-459
-
-
Lansing, T.J.1
McConnell, R.T.2
Duckett, D.R.3
Spehar, G.M.4
Knick, V.B.5
Hassler, D.F.6
-
19
-
-
10744221449
-
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polobox domain
-
PMID:14532005
-
Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, et al. The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polobox domain. Cell 2003; 115:83-95; PMID:14532005; http://dx.doi.org/ 10.1016/S0092-8674(03)00725-6.
-
(2003)
Cell
, vol.115
, pp. 83-95
-
-
Elia, A.E.1
Rellos, P.2
Haire, L.F.3
Chao, J.W.4
Ivins, F.J.5
Hoepker, K.6
-
20
-
-
43149093993
-
Inhibition of polo-like kinase 1 by blocking polobox domain-dependent protein-protein interactions
-
PMID:18482698
-
Reindl W, Yuan J, Krämer A, Strebhardt K, Berg T. Inhibition of polo-like kinase 1 by blocking polobox domain-dependent protein-protein interactions. Chem Biol 2008; 15:459-66; PMID:18482698; http:// dx.doi.org/10.1016/j.chembiol.2008.03.013.
-
(2008)
Chem Biol
, vol.15
, pp. 459-466
-
-
Reindl, W.1
Yuan, J.2
Krämer, A.3
Strebhardt, K.4
Berg, T.5
-
21
-
-
59049093510
-
Deficiency in chromosome congression by the inhibition of Plk1 polo box domaindependent recognition
-
PMID:19033445
-
Watanabe N, Sekine T, Takagi M, Iwasaki J, Imamoto N, Kawasaki H, et al. Deficiency in chromosome congression by the inhibition of Plk1 polo box domaindependent recognition. J Biol Chem 2009; 284:2344- 53; PMID:19033445; http://dx.doi.org/10.1074/jbc. M805308200.
-
(2009)
J Biol Chem
, vol.284
, pp. 2344-2353
-
-
Watanabe, N.1
Sekine, T.2
Takagi, M.3
Iwasaki, J.4
Imamoto, N.5
Kawasaki, H.6
-
22
-
-
80053229630
-
Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo
-
PMID:21839059
-
Yuan J, Sanhaji M, Krämer A, Reindl W, Hofmann M, Kreis NN, et al. Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo. Am J Pathol 2011; 179:2091- 9; PMID:21839059; http://dx.doi.org/10.1016/j. ajpath.2011.06.031.
-
(2011)
Am J Pathol
, vol.179
, pp. 2091-2099
-
-
Yuan, J.1
Sanhaji, M.2
Krämer, A.3
Reindl, W.4
Hofmann, M.5
Kreis, N.N.6
-
23
-
-
84860388896
-
Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel
-
PMID:21765407
-
Liu F, Park JE, Qian WJ, Lim D, Gräber M, Berg T, et al. Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel. Nat Chem Biol 2011; 7:595- 601; PMID:21765407; http://dx.doi.org/10.1038/ nchembio.614.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 595-601
-
-
Liu, F.1
Park, J.E.2
Qian, W.J.3
Lim, D.4
Gräber, M.5
Berg, T.6
-
24
-
-
68049112546
-
Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology
-
PMID:19474163
-
Schöffski P. Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. Oncologist 2009; 14:559-70; PMID:19474163; http://dx.doi.org/10.1634/theoncologist.2009-0010.
-
(2009)
Oncologist
, vol.14
, pp. 559-570
-
-
Schöffski, P.1
-
25
-
-
77955714290
-
Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network of Core Institutes (NOCI)
-
PMID:20471824
-
Schöffski P, Blay JY, De Greve J, Brain E, Machiels JP, Soria JC, et al. Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI). Eur J Cancer 2010; 46:2206- 15; PMID:20471824; http://dx.doi.org/10.1016/j. ejca.2010.03.039.
-
(2010)
Eur J Cancer
, vol.46
, pp. 2206-2215
-
-
Schöffski, P.1
Blay, J.Y.2
De Greve, J.3
Brain, E.4
Machiels, J.P.5
Soria, J.C.6
-
26
-
-
57149102928
-
Phase I dose escalation and pharmacokinetic study of BI 2536, a novel Polo-like kinase 1 inhibitor, in patients with advanced solid tumors
-
PMID:18955456
-
Mross K, Frost A, Steinbild S, Hedbom S, Rentschler J, Kaiser R, et al. Phase I dose escalation and pharmacokinetic study of BI 2536, a novel Polo-like kinase 1 inhibitor, in patients with advanced solid tumors. J Clin Oncol 2008; 26:5511-7; PMID:18955456; http://dx.doi.org/10.1200/JCO.2008.16.1547.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5511-5517
-
-
Mross, K.1
Frost, A.2
Steinbild, S.3
Hedbom, S.4
Rentschler, J.5
Kaiser, R.6
-
27
-
-
0038624074
-
Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells
-
PMID:12732729
-
Liu X, Erikson RL. Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells. Proc Natl Acad Sci USA 2003; 100:5789-94; PMID:12732729; http:// dx.doi.org/10.1073/pnas.1031523100.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5789-5794
-
-
Liu, X.1
Erikson, R.L.2
-
28
-
-
0037132736
-
Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells
-
PMID:12488480
-
Spänkuch-Schmitt B, Bereiter-Hahn J, Kaufmann M, Strebhardt K. Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells. J Natl Cancer Inst 2002; 94:1863- 77; PMID:12488480; http://dx.doi.org/10.1093/ jnci/94.24.1863.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1863-1877
-
-
Spänkuch-Schmitt, B.1
Bereiter-Hahn, J.2
Kaufmann, M.3
Strebhardt, K.4
-
29
-
-
33644767315
-
Normal cells, but not cancer cells, survive severe Plk1 depletion
-
PMID:16507989
-
Liu X, Lei M, Erikson RL. Normal cells, but not cancer cells, survive severe Plk1 depletion. Mol Cell Biol 2006; 26:2093-108; PMID:16507989; http://dx.doi. org/10.1128/MCB.26.6.2093-108.2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2093-2108
-
-
Liu, X.1
Lei, M.2
Erikson, R.L.3
-
30
-
-
16844369144
-
Small interfering RNA-mediated Polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals
-
PMID:15805268
-
Guan R, Tapang P, Leverson JD, Albert D, Giranda VL, Luo Y. Small interfering RNA-mediated Polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals. Cancer Res 2005; 65:2698-704; PMID:15805268; http://dx.doi. org/10.1158/0008-5472.CAN-04-2131.
-
(2005)
Cancer Res
, vol.65
, pp. 2698-2704
-
-
Guan, R.1
Tapang, P.2
Leverson, J.D.3
Albert, D.4
Giranda, V.L.5
Luo, Y.6
-
31
-
-
77954597123
-
Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability
-
PMID:20571075
-
Degenhardt Y, Greshock J, Laquerre S, Gilmartin AG, Jing J, Richter M, et al. Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability. Mol Cancer Ther 2010; 9:2079-89; PMID:20571075; http:// dx.doi.org/10.1158/1535-7163.MCT-10-0095.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 2079-2089
-
-
Degenhardt, Y.1
Greshock, J.2
Laquerre, S.3
Gilmartin, A.G.4
Jing, J.5
Richter, M.6
-
32
-
-
77958574408
-
The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro
-
PMID:20886032
-
Lu B, Mahmud H, Maass AH, Yu B, van Gilst WH, de Boer RA, et al. The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro. PLoS One 2010; 5:12963; PMID:20886032; http://dx.doi.org/10.1371/journal. pone.0012963.
-
(2010)
PLoS One
, vol.5
, pp. 12963
-
-
Lu, B.1
Mahmud, H.2
Maass, A.H.3
Yu, B.4
Van Gilst, W.H.5
De Boer, R.A.6
-
33
-
-
0027358723
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
PMID:8221889
-
Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 1993; 75:495-505; PMID:8221889; http:// dx.doi.org/10.1016/0092- 8674(93)90384-3.
-
(1993)
Cell
, vol.75
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
34
-
-
77958020836
-
Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells
-
PMID:20661218
-
Kreis NN, Sanhaji M, Krämer A, Sommer K, Rödel F, Strebhardt K, et al. Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells. Oncogene 2010; 29:5591-603; PMID:20661218; http://dx.doi. org/10.1038/onc.2010.290.
-
(2010)
Oncogene
, vol.29
, pp. 5591-5603
-
-
Kreis, N.N.1
Sanhaji, M.2
Krämer, A.3
Sommer, K.4
Rödel, F.5
Strebhardt, K.6
-
35
-
-
33846523617
-
Targeted anti-mitotic therapies: Can we improve on tubulin agents?
-
PMID:17251917
-
Jackson JR, Patrick DR, Dar MM, Huang PS. Targeted anti-mitotic therapies: can we improve on tubulin agents? Nat Rev Cancer 2007; 7:107-17; PMID:17251917; http://dx.doi.org/10.1038/nrc2049.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 107-117
-
-
Jackson, J.R.1
Patrick, D.R.2
Dar, M.M.3
Huang, P.S.4
-
36
-
-
77958470977
-
p53-dependent repression of pololike kinase-1 (PLK1)
-
PMID:20962589
-
McKenzie L, King S, Marcar L, Nicol S, Dias SS, Schumm K, et al. p53-dependent repression of pololike kinase-1 (PLK1). Cell Cycle 2010; 9:4200-12; PMID:20962589; http://dx.doi.org/10.4161/ cc.9.20.13532.
-
(2010)
Cell Cycle
, vol.9
, pp. 4200-4212
-
-
McKenzie, L.1
King, S.2
Marcar, L.3
Nicol, S.4
Dias, S.S.5
Schumm, K.6
-
37
-
-
2942623616
-
Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation
-
PMID:15024021
-
Ando K, Ozaki T, Yamamoto H, Furuya K, Hosoda M, Hayashi S, et al. Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation. J Biol Chem 2004; 279:25549-61; PMID:15024021; http://dx.doi.org/10.1074/jbc.M314182200.
-
(2004)
J Biol Chem
, vol.279
, pp. 25549-25561
-
-
Ando, K.1
Ozaki, T.2
Yamamoto, H.3
Furuya, K.4
Hosoda, M.5
Hayashi, S.6
-
38
-
-
67650529837
-
Plk1-mediated phosphorylation of Topors regulates p53 stability
-
PMID:19473992
-
Yang X, Li H, Zhou Z, Wang WH, Deng A, Andrisani O, et al. Plk1-mediated phosphorylation of Topors regulates p53 stability. J Biol Chem 2009; 284:18588- 92; PMID:19473992; http://dx.doi.org/10.1074/jbc. C109.001560.
-
(2009)
J Biol Chem
, vol.284
, pp. 18588-18592
-
-
Yang, X.1
Li, H.2
Zhou, Z.3
Wang, W.H.4
Deng, A.5
Andrisani, O.6
-
39
-
-
62649112876
-
A part of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53
-
PMID:19225112
-
Sur S, Pagliarini R, Bunz F, Rago C, Diaz LA Jr, Kinzler KW, et al. A part of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53. Proc Natl Acad Sci USA 2009; 106:3964- 9; PMID:19225112; http://dx.doi.org/10.1073/ pnas.0813333106.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3964-3969
-
-
Sur, S.1
Pagliarini, R.2
Bunz, F.3
Rago, C.4
Diaz Jr., L.A.5
Kinzler, K.W.6
-
40
-
-
70349438905
-
The expanding universe of p53 targets
-
PMID:19776742
-
Menendez D, Inga A, Resnick MA. The expanding universe of p53 targets. Nat Rev Cancer 2009; 9:724-37; PMID:19776742; http://dx.doi.org/10.1038/nrc2730.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 724-737
-
-
Menendez, D.1
Inga, A.2
Resnick, M.A.3
-
41
-
-
70450270900
-
Awakening guardian angels: Drugging the p53 pathway
-
PMID:19935675
-
Brown CJ, Lain S, Verma CS, Fersht AR, Lane DP. Awakening guardian angels: drugging the p53 pathway. Nat Rev Cancer 2009; 9:862-73; PMID:19935675; http://dx.doi.org/10.1038/nrc2763.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 862-873
-
-
Brown, C.J.1
Lain, S.2
Verma, C.S.3
Fersht, A.R.4
Lane, D.P.5
-
43
-
-
79960464440
-
Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture
-
PMID:21447859
-
Apontes P, Leontieva OV, Demidenko ZN, Li F, Blagosklonny MV. Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture. Oncotarget 2011; 2:222-33; PMID:21447859.
-
(2011)
Oncotarget
, vol.2
, pp. 222-233
-
-
Apontes, P.1
Leontieva, O.V.2
Demidenko, Z.N.3
Li, F.4
Blagosklonny, M.V.5
-
44
-
-
33645573673
-
The role of the p53 molecule in cancer therapies with radiation and/or hyperthermia
-
PMID:17998646
-
Ohnishi T. The role of the p53 molecule in cancer therapies with radiation and/or hyperthermia. J Cancer Res Ther 2005; 1:147-50; PMID:17998646; http:// dx.doi.org/10.4103/0973-1482.19594.
-
(2005)
J Cancer Res Ther
, vol.1
, pp. 147-150
-
-
Ohnishi, T.1
-
45
-
-
79960468258
-
Exploiting p53 status to enhance effectiveness of chemotherapy by lowering associated toxicity
-
PMID:21487160
-
Steelman LS, Martelli AM, Nicoletti F, McCubrey JA. Exploiting p53 status to enhance effectiveness of chemotherapy by lowering associated toxicity. Oncotarget 2011; 2:109-12; PMID:21487160.
-
(2011)
Oncotarget
, vol.2
, pp. 109-112
-
-
Steelman, L.S.1
Martelli, A.M.2
Nicoletti, F.3
McCubrey, J.A.4
-
46
-
-
79956035239
-
Evaluation of an Actinomycin D/VX-680 aurora kinase inhibitor combination in p53-based cyclotherapy
-
PMID:21317459
-
Rao B, van Leeuwen IM, Higgins M, Campbel J, Thompson AM, Lane DP, et al. Evaluation of an Actinomycin D/VX-680 aurora kinase inhibitor combination in p53-based cyclotherapy. Oncotarget 2010; 1:639-50; PMID:21317459.
-
(2010)
Oncotarget
, vol.1
, pp. 639-650
-
-
Rao, B.1
Van Leeuwen, I.M.2
Higgins, M.3
Campbel, J.4
Thompson, A.M.5
Lane, D.P.6
-
47
-
-
59449101448
-
Long-term downregulation of Polo-like kinase 1 increases the cyclin-dependent kinase inhibitor p21(WAF1/CIP1)
-
PMID:19177004
-
Kreis NN, Sommer K, Sanhaji M, Krämer A, Matthess Y, Kaufmann M, et al. Long-term downregulation of Polo-like kinase 1 increases the cyclin-dependent kinase inhibitor p21(WAF1/CIP1). Cell Cycle 2009; 8:460- 72; PMID:19177004; http://dx.doi.org/10.4161/ cc.8.3.7651.
-
(2009)
Cell Cycle
, vol.8
, pp. 460-472
-
-
Kreis, N.N.1
Sommer, K.2
Sanhaji, M.3
Krämer, A.4
Matthess, Y.5
Kaufmann, M.6
-
48
-
-
77952625286
-
Functional and spatial regulation of mitotic centromere-associated kinesin by cyclindependent kinase 1
-
PMID:20368358
-
Sanhaji M, Friel CT, Kreis NN, Krämer A, Martin C, Howard J, et al. Functional and spatial regulation of mitotic centromere-associated kinesin by cyclindependent kinase 1. Mol Cell Biol 2010; 30:2594- 607; PMID:20368358; http://dx.doi.org/10.1128/ MCB.00098-10.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 2594-2607
-
-
Sanhaji, M.1
Friel, C.T.2
Kreis, N.N.3
Krämer, A.4
Martin, C.5
Howard, J.6
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