-
1
-
-
56349102675
-
Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency-lessons learned from monogenic disorders in mice and men
-
Westerberg L.S., Klein C., Snapper S.B. Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency-lessons learned from monogenic disorders in mice and men. Curr. Opin. Immunol. 2008, 20:646-654.
-
(2008)
Curr. Opin. Immunol.
, vol.20
, pp. 646-654
-
-
Westerberg, L.S.1
Klein, C.2
Snapper, S.B.3
-
2
-
-
0022617990
-
Type I diabetes mellitus. A chronic autoimmune disease
-
Eisenbarth G.S. Type I diabetes mellitus. A chronic autoimmune disease. N. Engl. J. Med. 1986, 314:1360-1368.
-
(1986)
N. Engl. J. Med.
, vol.314
, pp. 1360-1368
-
-
Eisenbarth, G.S.1
-
3
-
-
50949092228
-
Autoimmune mechanisms in type 1 diabetes
-
Knip M., Siljander H. Autoimmune mechanisms in type 1 diabetes. Autoimmun. Rev. 2008, 7:550-557.
-
(2008)
Autoimmun. Rev.
, vol.7
, pp. 550-557
-
-
Knip, M.1
Siljander, H.2
-
4
-
-
29444433680
-
Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes
-
Pinkse G.G., Tysma O.H., Bergen C.A., Kester M.G., Ossendorp F., van Veelen P.A., et al. Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes. Proc. Natl. Acad. Sci. USA 2005, 102:18425-18430.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 18425-18430
-
-
Pinkse, G.G.1
Tysma, O.H.2
Bergen, C.A.3
Kester, M.G.4
Ossendorp, F.5
van Veelen, P.A.6
-
5
-
-
0038303191
-
The role of T-cells in the pathogenesis of Type 1 diabetes: from cause to cure
-
Roep B.O. The role of T-cells in the pathogenesis of Type 1 diabetes: from cause to cure. Diabetologia 2003, 46:305-321.
-
(2003)
Diabetologia
, vol.46
, pp. 305-321
-
-
Roep, B.O.1
-
6
-
-
33847629171
-
Translational mini-review series on type 1 diabetes: systematic analysis of T cell epitopes in autoimmune diabetes
-
Di Lorenzo T.P., Peakman M., Roep B.O. Translational mini-review series on type 1 diabetes: systematic analysis of T cell epitopes in autoimmune diabetes. Clin. Exp. Immunol. 2007, 148:1-16.
-
(2007)
Clin. Exp. Immunol.
, vol.148
, pp. 1-16
-
-
Di Lorenzo, T.P.1
Peakman, M.2
Roep, B.O.3
-
8
-
-
0028584260
-
Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives
-
Bingley P.J., Christie M.R., Bonifacio E., Bonfanti R., Shattock M., Fonte M.T., et al. Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives. Diabetes 1994, 43:1304-1310.
-
(1994)
Diabetes
, vol.43
, pp. 1304-1310
-
-
Bingley, P.J.1
Christie, M.R.2
Bonifacio, E.3
Bonfanti, R.4
Shattock, M.5
Fonte, M.T.6
-
9
-
-
0030175880
-
Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes
-
Verge C.F., Gianani R., Kawasaki E., Yu L., Pietropaolo M., Chase H.P., et al. Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes. J. Autoimmun. 1996, 9:379-383.
-
(1996)
J. Autoimmun.
, vol.9
, pp. 379-383
-
-
Verge, C.F.1
Gianani, R.2
Kawasaki, E.3
Yu, L.4
Pietropaolo, M.5
Chase, H.P.6
-
10
-
-
17944381519
-
The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study
-
Kimpimäki T., Kupila A., Hämäläinen A.M., Kukko M., Kulmala P., Savola K., et al. The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study. J. Clin. Endocrinol. Metab. 2001, 86:4782-4788.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 4782-4788
-
-
Kimpimäki, T.1
Kupila, A.2
Hämäläinen, A.M.3
Kukko, M.4
Kulmala, P.5
Savola, K.6
-
11
-
-
33644761987
-
Natural history of type 1 diabetes
-
Achenbach P., Bonifacio E., Koczwara K., Ziegler A.G. Natural history of type 1 diabetes. Diabetes 2005, 54(Suppl. 2):S25-S31.
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Achenbach, P.1
Bonifacio, E.2
Koczwara, K.3
Ziegler, A.G.4
-
12
-
-
0026046093
-
Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10
-
Karlsen A.E., Hagopian W.A., Grubin C.E., Dube S., Disteche C.M., Adler D.A., et al. Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10. Proc. Natl. Acad. Sci. USA 1991, 88:8337-8341.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 8337-8341
-
-
Karlsen, A.E.1
Hagopian, W.A.2
Grubin, C.E.3
Dube, S.4
Disteche, C.M.5
Adler, D.A.6
-
13
-
-
0242364727
-
A comprehensive guide to antibody and T-cell responses in type 1 diabetes
-
Lieberman S.M., DiLorenzo T.P. A comprehensive guide to antibody and T-cell responses in type 1 diabetes. Tissue Antigens 2003, 62:359-377.
-
(2003)
Tissue Antigens
, vol.62
, pp. 359-377
-
-
Lieberman, S.M.1
DiLorenzo, T.P.2
-
14
-
-
0007102288
-
Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients
-
Endl J., Otto H., Jung G., Dreisbusch B., Donie F., Stahl P., et al. Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients. J. Clin. Invest. 1997, 99:2405-2415.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2405-2415
-
-
Endl, J.1
Otto, H.2
Jung, G.3
Dreisbusch, B.4
Donie, F.5
Stahl, P.6
-
15
-
-
10544223741
-
Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401
-
Wicker L.S., Chen S.L., Nepom G.T., Elliott J.F., Freed D.C., Bansal A., et al. Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401. J. Clin. Invest. 1996, 98:2597-2603.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2597-2603
-
-
Wicker, L.S.1
Chen, S.L.2
Nepom, G.T.3
Elliott, J.F.4
Freed, D.C.5
Bansal, A.6
-
16
-
-
27844561478
-
4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects
-
4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects. J. Autoimmun. 2005, 25:235-243.
-
(2005)
J. Autoimmun.
, vol.25
, pp. 235-243
-
-
Öling, V.1
Marttila, J.2
Ilonen, J.3
Kwok, W.W.4
Nepom, G.5
Knip, M.6
-
18
-
-
0036312395
-
Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects
-
Reijonen H., Novak E.J., Kochik S., Heninger A., Liu A.W., Kwok W.W. Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects. Diabetes 2002, 51:1375-1382.
-
(2002)
Diabetes
, vol.51
, pp. 1375-1382
-
-
Reijonen, H.1
Novak, E.J.2
Kochik, S.3
Heninger, A.4
Liu, A.W.5
Kwok, W.W.6
-
19
-
-
67651152594
-
Changes in autoreactive T cell avidity during type 1 diabetes development
-
Standifer N.E., Burwell E.A., Gersuk V.H., Greenbaum C.J., Nepom G.T. Changes in autoreactive T cell avidity during type 1 diabetes development. Clin. Immunol. 2009, 132:312-320.
-
(2009)
Clin. Immunol.
, vol.132
, pp. 312-320
-
-
Standifer, N.E.1
Burwell, E.A.2
Gersuk, V.H.3
Greenbaum, C.J.4
Nepom, G.T.5
-
20
-
-
50549103960
-
T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies
-
Marttila J., Huttunen S., Vaarala O., Suzuki K., Elliott J.F., Närvänen A., et al. T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies. J. Autoimmun. 2008, 31:142-148.
-
(2008)
J. Autoimmun.
, vol.31
, pp. 142-148
-
-
Marttila, J.1
Huttunen, S.2
Vaarala, O.3
Suzuki, K.4
Elliott, J.F.5
Närvänen, A.6
-
21
-
-
27744524215
-
The insulin A-chain epitope recognized by human T cells is posttranslationally modified
-
Mannering S.I., Harrison L.C., Williamson N.A., Morris J.S., Thearle D.J., Jensen K.P., et al. The insulin A-chain epitope recognized by human T cells is posttranslationally modified. J. Exp. Med. 2005, 202:1191-1197.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1191-1197
-
-
Mannering, S.I.1
Harrison, L.C.2
Williamson, N.A.3
Morris, J.S.4
Thearle, D.J.5
Jensen, K.P.6
-
23
-
-
18744385526
-
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope
-
Kent S.C., Chen Y., Bregoli L., Clemmings S.M., Kenyon N.S., Ricordi C., et al. Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope. Nature 2005, 435:224-228.
-
(2005)
Nature
, vol.435
, pp. 224-228
-
-
Kent, S.C.1
Chen, Y.2
Bregoli, L.3
Clemmings, S.M.4
Kenyon, N.S.5
Ricordi, C.6
-
24
-
-
0037006432
-
Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity
-
Durinovic-Bello I., Boehm B.O., Ziegler A.G. Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity. J. Autoimmun. 2002, 18:55-66.
-
(2002)
J. Autoimmun.
, vol.18
, pp. 55-66
-
-
Durinovic-Bello, I.1
Boehm, B.O.2
Ziegler, A.G.3
-
25
-
-
0036212794
-
GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes
-
Viglietta V., Kent S.C., Orban T., Hafler D.A. GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes. J. Clin. Invest. 2002, 109:895-903.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 895-903
-
-
Viglietta, V.1
Kent, S.C.2
Orban, T.3
Hafler, D.A.4
-
26
-
-
2442522323
-
Autoreactive T cells in healthy individuals
-
Danke N.A., Koelle D.M., Yee C., Beheray S., Kwok W.W. Autoreactive T cells in healthy individuals. J. Immunol. 2004, 172:5967-5972.
-
(2004)
J. Immunol.
, vol.172
, pp. 5967-5972
-
-
Danke, N.A.1
Koelle, D.M.2
Yee, C.3
Beheray, S.4
Kwok, W.W.5
-
28
-
-
33644758318
-
Coexpression of CD25 and OX40 (CD134) receptors delineates autoreactive T-cells in type 1 diabetes
-
Endl J., Rosinger S., Schwarz B., Friedrich S.O., Rothe G., Karges W., et al. Coexpression of CD25 and OX40 (CD134) receptors delineates autoreactive T-cells in type 1 diabetes. Diabetes 2006, 55:50-60.
-
(2006)
Diabetes
, vol.55
, pp. 50-60
-
-
Endl, J.1
Rosinger, S.2
Schwarz, B.3
Friedrich, S.O.4
Rothe, G.5
Karges, W.6
-
29
-
-
38449111219
-
Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes
-
Monti P., Scirpoli M., Rigamonti A., Mayr A., Jaeger A., Bonfanti R., et al. Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes. J. Immunol. 2007, 179:5785-5792.
-
(2007)
J. Immunol.
, vol.179
, pp. 5785-5792
-
-
Monti, P.1
Scirpoli, M.2
Rigamonti, A.3
Mayr, A.4
Jaeger, A.5
Bonfanti, R.6
-
30
-
-
85047690395
-
Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health
-
Arif S., Tree T.I., Astill T.P., Tremble J.M., Bishop A.J., Dayan C.M., et al. Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health. J. Clin. Invest. 2004, 113:451-463.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 451-463
-
-
Arif, S.1
Tree, T.I.2
Astill, T.P.3
Tremble, J.M.4
Bishop, A.J.5
Dayan, C.M.6
-
31
-
-
0035079772
-
Feasibility of genetic and immunological prediction of type I diabetes in a population-based birth cohort
-
Kupila A., Muona P., Simell T., Arvilommi P., Savolainen H., Hämäläinen A.M., et al. Feasibility of genetic and immunological prediction of type I diabetes in a population-based birth cohort. Diabetologia 2001, 44:290-297.
-
(2001)
Diabetologia
, vol.44
, pp. 290-297
-
-
Kupila, A.1
Muona, P.2
Simell, T.3
Arvilommi, P.4
Savolainen, H.5
Hämäläinen, A.M.6
-
32
-
-
0042664186
-
HLA DR-DQ-encoded genetic determinants of childhood-onset type 1 diabetes in Finland: an analysis of 622 nuclear families
-
Hermann R., Turpeinen H., Laine A.P., Veijola R., Knip M., Simell O., et al. HLA DR-DQ-encoded genetic determinants of childhood-onset type 1 diabetes in Finland: an analysis of 622 nuclear families. Tissue Antigens 2003, 62:162-169.
-
(2003)
Tissue Antigens
, vol.62
, pp. 162-169
-
-
Hermann, R.1
Turpeinen, H.2
Laine, A.P.3
Veijola, R.4
Knip, M.5
Simell, O.6
-
33
-
-
21044442220
-
Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population
-
Kukko M., Kimpimäki T., Korhonen S., Kupila A., Simell S., Veijola R., et al. Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population. J. Clin. Endocrinol. Metab. 2005, 90:2712-2717.
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 2712-2717
-
-
Kukko, M.1
Kimpimäki, T.2
Korhonen, S.3
Kupila, A.4
Simell, S.5
Veijola, R.6
-
34
-
-
55749104546
-
Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial
-
Näntö-Salonen K., Kupila A., Simell S., Siljander H., Salonsaari T., Hekkala A., et al. Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial. Lancet 2008, 372:1746-1755.
-
(2008)
Lancet
, vol.372
, pp. 1746-1755
-
-
Näntö-Salonen, K.1
Kupila, A.2
Simell, S.3
Siljander, H.4
Salonsaari, T.5
Hekkala, A.6
-
35
-
-
0036016262
-
Modulation of T cell response to hGAD65 peptide epitopes
-
Masewicz S.A., Papadopoulos G.K., Swanson E., Moriarity L., Moustakas A.K., Nepom G.T. Modulation of T cell response to hGAD65 peptide epitopes. Tissue Antigens 2002, 59:101-112.
-
(2002)
Tissue Antigens
, vol.59
, pp. 101-112
-
-
Masewicz, S.A.1
Papadopoulos, G.K.2
Swanson, E.3
Moriarity, L.4
Moustakas, A.K.5
Nepom, G.T.6
-
36
-
-
70350534475
-
Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes
-
Herold K.C., Brooks-Worrell B., Palmer J., Dosch H.M., Peakman M., Gottlieb P. Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes. Diabetes 2009, 58:2588-2595.
-
(2009)
Diabetes
, vol.58
, pp. 2588-2595
-
-
Herold, K.C.1
Brooks-Worrell, B.2
Palmer, J.3
Dosch, H.M.4
Peakman, M.5
Gottlieb, P.6
-
37
-
-
0037237655
-
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood
-
Trudeau J.D., Kelly-Smith C., Verchere C.B., Elliott J.F., Dutz J.P., Finegood D.T., et al. Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood. J. Clin. Invest. 2003, 111:217-223.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 217-223
-
-
Trudeau, J.D.1
Kelly-Smith, C.2
Verchere, C.B.3
Elliott, J.F.4
Dutz, J.P.5
Finegood, D.T.6
|