Traditional uses, phytochemistry and pharmacology of Clerodendron glandulosum Coleb – a review

Asian Pacific Journal of Tropical Medicine

Volumn 5, Issue 1, 2012, Pages 1-6

  Jadeja, Ravirajsinh N ^a   Thounaojam, Menaka C ^a   Singh, Thouchom Brojendro ^b   Devkar, Ranjitsinh V ^a   Ramachandran, A V ^a  

^a M S UNIVERSITY OF BARODA   (India)

^b Oriental College   (India)

Author keywords

Atherosclerosis; Clerodendron glandulosum. Coleb; Hypertension; Insulin resistance; Obesity

Indexed keywords

2 PENTADECYN 1 OL; ALKALOID; ALPHA TOCOPHEROL; ANTHRAQUINONE DERIVATIVE; ASCORBIC ACID; CARBON TETRACHLORIDE; CLERODENDRON GLANDULOSUM EXTRACT; FLAVONOID; GALLIC ACID; HENTRIACONTANE; HEXACOSANE; HEXANE; LOW DENSITY LIPOPROTEIN; LUPEOL; NOROLEAN 12 ENE; OCTACOSANE; PALMITIC ACID; PHENOL DERIVATIVE; PHYTOSTEROL; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; POLYPHENOL DERIVATIVE; QUERCETIN; SAPONIN DERIVATIVE; STRONGYLOSTER; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANTIOBESITY AGENT; ANTIOXIDANT; PROTECTIVE AGENT; SCAVENGER;

ANTIDIABETIC ACTIVITY; ANTIHYPERTENSIVE ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CLERODENDRON GLANDULOSUM; DRUG ACTIVITY; DRUG EFFECT; EXPERIMENTAL ATHEROSCLEROSIS; EXPERIMENTAL HYPERLIPIDEMIA; EXPERIMENTAL STEATOHEPATITIS; FREE RADICAL SCAVENGING ASSAY; IN VITRO STUDY; IN VIVO STUDY; LIPID OXIDATION; LIVER PROTECTION; LIVER TOXICITY; MACROPHAGE; METABOLIC SYNDROME X; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PHYTOCHEMISTRY; PLANT LEAF; PRIORITY JOURNAL; TOXICITY TESTING; VERBENACEAE; ANIMAL; ATHEROSCLEROSIS; CHEMISTRY; CLERODENDRUM; EVIDENCE BASED MEDICINE; FATTY LIVER; HUMAN; INDIA; METHODOLOGY; MOUSE; PHYTOTHERAPY; REVIEW; TRADITIONAL MEDICINE;

ANIMALS; ANTI-OBESITY AGENTS; ANTIHYPERTENSIVE AGENTS; ANTIOXIDANTS; ATHEROSCLEROSIS; CLERODENDRUM; EVIDENCE-BASED MEDICINE; FATTY LIVER; FREE RADICAL SCAVENGERS; HUMANS; HYPOGLYCEMIC AGENTS; INDIA; MEDICINE, TRADITIONAL; MICE; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; PROTECTIVE AGENTS;

EID: 84857137037     PISSN: 19957645     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1995-7645(11)60236-8     Document Type: Article

References (51)

1. Anonymous, Clerodendrum Carolus Linnaeus. Species Plantarum, 2, 1753, 637.
2. Quattrocchi, U, CRC world dictionary of plant names, 2000, CRC Press, Boca Raton, 559.
3. Mabberley, DJ, Mabberley's plant-book, 3rd ed., 2008, Cambridge University Press, Cambridge.
4. Shrivastava, N, Patel, T, Clerodendrum and healthcare: an overview. Medicinal Aromatic Plant Sci Biotech 1 (2007), 142–150.
5. Moldenke, HN, Notes on the genus Clerodendrum (Verbenaceae) IV. Phytologia 57 (1985), 334–365.
6. Rueda, RM, The genus Clerodendrum (Verbenaceae) in Mesoamerica. Ann Missouri Bot Garden 80 (1993), 870–890.
7. Deb, DB, Flora of Tripura State, 1983, Today and Tomorrow's Printers, New Delhi, 107.
8. Anonymous. Hidaklon-book of traditional medicine, an archaic literature 16th century. Imphal: Chandrasingh Memorial Manuscript Library.
9. Anonymous. Leirol, book of flowers, an archaic literature 17th century. Imphal: Chandrasingh Memorial Manuscript Library.
10. Anonymous. Leirol, lumbuba, book of flowers, an archaic literature 17th century. Imphal: Chandrasingh Memorial Manuscript, Library.
11. Kala, CP, Ethnomedicinal botany of the Apatani in the Eastern Himalayan region of India. J Ethnobiol Ethnomed, 1, 2005, 11.
12. Deb, S, Arunachalam, A, Das, AK, Indigenous knowledge of Nyishi tribes on traditional agro forestry systems. Indian J Trad Knowl 8 (2009), 41–46.
13. Jubilee, P, Subhan, CN, Islamb, M, Ethnobotany of medicinal plants from Dibru-Saikhowa biosphere reserve of Northeast India. Fitoterapia 76 (2005), 121–127.
14. Jadeja, RN, Thounaojam, MC, Ansarullah, Devkar, RV, Ramchandran, AV, A prelimnary study on hypolipidemic effect of aqueous extract of Clerodendron glandulosum. Coleb. Int J Green Pharm 2 (2009), 119–123.
15. Jadeja, RN, Thounaojam, MC, Ansarullah, Ramchandran, AV, Devkar, RV, Phytochemical constituents and free radical scavenging activity of Clerodendron glandulosum Coleb methanolic extract. J Compl Integr Med 6 (2009), 1–23.
16. Bandyopadhyay, U, Das, D, Banerjee, RK, Reactive oxygen species: oxidative damage and pathogenesis. Curr Sci, 77, 1999, 5.
17. Thounaojam, MC, Jadeja, RN, Devkar, RV, Ramachandran, AV, Antioxidant and free radical scavenging activity of Sida rhomboidea. Roxb methanolic extract determined using different in vitro models. Bol Latinoam Caribe Plant Med Aromat 9 (2010), 191–198.
18. Al-Attar, AM, Physiological and biochemical alterations in Sprague-Dawley female rats subjected to high fat diet and intermittent fasting. J Appl Sci Res 6 (2010), 2096–2104.
19. Mukerjee, PK, Plant products with hypocholesterolemic potentials. Taylor, L., (eds.) Advances in food and nutrition research, 2003, Elsevier, Netherlands, 278–339.
20. Richard, NF, Statin drugs. [Online]. Available from: http://heartdisease.about.com/b/2008/01/14/enhance-at-best-no-benefit-from-vytorinor-zetia.htm [Accessed on 2008].
21. Wilson, PWF, High density lipoprotein, low density lipoprotein and coronary heart disease. Am J Cardiol 66 (1990), 7–10.
22. Jadeja, RN, Thounaojam, MC, Ansarullah, Devkar, RV, Ramchandran, AV, Clerodendron glandulosum Coleb. Verbenaceae, ameliorates high fat diet-induced alteration in lipid and cholesterol metabolism in rats. Revista Brasileira de Pharmacognosia 20 (2010), 117–123.
23. Grundy, SM, Brewer, HB Jr, Cleeman, JI, Smith, SC Jr, Definition of metabolic syndrome report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on scientific issues related to definition. Circulation 109 (2004), 433–438.
24. Eckel, RH, Grundy, SM, Zimmet, PZ, The metabolic syndrome. Lancet 365 (2005), 1415–1428.
25. Basciano, H, Federico, L, Adeli, K, Fructose, insulin resistance, and metabolic dyslipidemia. Nutr Metab, 2, 2005, 5.
26. Mohammd, RS, Mehdi, H, Ahamd, RS, Prevention of high fructose-induced metabolic syndrome in male wistar rats by aqueous extract of Tamarindus Indica seed. Acta Medica Iranica, 49, 2011, 5.
27. Jadeja, RN, Thounaojam, MC, Ansarullah, Patel, VB, Devkar, RV, Ramachandran, AV, Protective effect of Clerodendron glandulosum extract against experimentally induced metabolic syndrome in rats. Pharm Biol 48 (2010), 1312–1319.
28. Duvnjak, M, Lerotić I, Baršić N, Tomašić V, Jukić LV, Velagić V, Pathogenesis and management issues for non-alcoholic fatty liver disease. World J Gastroenterol 13 (2007), 4539–4550.
29. Nakamoto, K, Takayama, F, Mankura, M, Hidaka, Y, Egashira, T, Ogino, T, et al. Beneficial-effects of fermented green tea extract in a rat model of non-alcoholic steatohepatitis. J Clin Biochem Nutr 44 (2009), 239–246.
30. Jadeja, RN, Thounaojam, MC, Dandekar, DS, Devkar, RV, Ramachandran, AV, Clerodendron glandulosum. Coleb extract ameliorates high fat diet/fatty acid induced lipotoxicity in experimental models of non alcoholic steatohepatitis. Food Chem Toxicol 48 (2010), 3424–3431.
31. Hoffman, DJ, Obesity in developing countries: causes and implications. Food Nutr Agric 28 (2001), 35–44.
32. Nakayama, T, Suzuki, S, Kudo, H, Sassa, S, Nomura, M, Sakamoto, S, Effects of three Chinese herbal medicines on plasma and liver lipids in mice fed a high-fat diet. J Ethnopharmacol 109 (2007), 236–240.
33. Mayer, MA, Hocht, C, Puyo, A, Taira, CA, Recent advances in obesity pharmacotherapy. Curr Clin Pharmacol 4 (2009), 53–61.
34. Yun, JW, Possible anti-obesity therapeutics from nature-a review. Phytochemistry 71 (2010), 1625–1641.
35. Jadeja, RN, Thounaojam, MC, Ramani, UV, Devkar, RV, Ramachandran, AV, Anti-obesity potential of Clerodendron glandulosum. Coleb leaf aqueous extract. J Ethnopharmacol 135 (2011), 338–343.
36. Libby, P, Ridker, PM, Hansson, GK, Progress and challenges in translating the biology of atherosclerosis. Nature 473 (2011), 317–325.
37. Cushing, SD, Berliner, JA, Valente, AJ, Territo, MC, Navab, M, Parhami, F, et al. Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci USA 87 (1999), 5134–5138.
38. Stocker, R, Keaney, JF Jr, Role of oxidative modifications in atherosclerosis. Physiol Rev 84 (2004), 1381–1478.
39. Boullier, A, Bird, DA, Chang, MK, Dennis, EA, Friedman, P, Gillotre-Taylor, K, et al. Scavenger receptors, oxidized LDL, and atherosclerosis. Ann N Y Acad Sci 947 (2001), 214–222.
40. Jadeja, RN, Thounaojam, MC, Devkar, RV, Ramachandran, AV, Clerodendron glandulosum. Coleb extract prevents in vitro human LDL oxidation and oxidized LDL induced Apoptosis in human monocyte derived macrophages. Food Chem Toxicol 49 (2011), 1195–1202.
41. Jadeja, RN, Thounaojam, MC, Jain, M, Devkar, RV, Ramachandran, AV, Clerodendron glandulosum. Coleb leaf extract attenuates in vitro macrophage differentiation and expression of VCAM-1 and P-selectin in thoracic aorta of atherogenic diet fed rats. Immunopharm Immunotox, 2011, 10.3109/08923973.2011.618136.
42. Lodhi, S, Singhai, AK, Preliminary pharmacological evaluation of Martynia annua Linn leaves for wound healing. Asian Pac J Trop Biomed 1:6 (2011), 421–427.
43. Paul, KR, Irudayaraj, V, Johnson, M, Patric, DR, Phytochemical and anti-bacterial activity of epidermal glands extract of Christella parasitica (L.) H. Lev. Asian Pac J Trop Biomed 1:1 (2011), 8–11.
44. Mithraja, MJ, Antonisamy, JM, Mahesh, M, Paul, ZM, Jeeva, S, Phytochemical studies on Azolla pinnata R. Br., Marsilea minuta L. and Salvinia molesta Mitch. Asian Pac J Trop Biomed 1:Suppl 1 (2011), S26–S29.
45. Kiruba, S, Mahesh, M, Paul, ZM, Jeeva, S, Preliminary phytochemical screening of the pericarp of Crataeva magna (Lour.) DC. - a medicinal tree. Asian Pac J Trop Biomed 1:Suppl 1 (2011), S129–S130.
46. Kiruba, S, Mahesh, M, Nisha, SR, Paul, ZM, Jeeva, S, Phytochemical analysis of the flower extracts of Rhododendron arboreum Sm. ssp. nilagiricum (Zenker) Tagg. Asian Pac J Trop Biomed 1:Suppl 2 (2011), S284–S286.
47. Williams, R, Global challenges in liver disease. Hepatology 44 (2006), 521–526.
48. Jadeja, RN, Thounaojam, MC, Ansarullah, Jadav, SV, Patel, MD, Patel, DK, et al. Toxicological evaluation and hepatoprotective potential of Clerodendron glandulosum Coleb leaf extract. Hum Exp Toxicol 30 (2011), 63–70.
49. Verma, S, Singh, SP, Current and future status of herbal medicines. Veterinary World 1 (2010), 347–350.
50. WHO, Traditional herbal remedies for primary health care. [Online]. Available from: http://apps.who.int/bookorders/anglais/detart1.jsp?sesslan=1&codlan=1&codcol=54&codcch=18 [Accessed on 2010].
51. Mosihuzzaman, M, Choudhary, MI, Protocols on safety, efficacy, standardization, and documentation of herbal medicine. Pure Appl Chem 80 (2008), 2195–2230.