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Volumn 109, Issue 5, 2012, Pages 1691-1696

In-feed antibiotic effects on the swine intestinal microbiome

Author keywords

BioTrove microarray; Intestinal microbiota; Metagenomics; Microbiome shifts; Swine bacteria

Indexed keywords

AMINOGLYCOSIDE PHOSPHOTRANSFERASE; ANTIBIOTIC AGENT; CHLORTETRACYCLINE; PENICILLIN G; SULFADIMIDINE; UNCLASSIFIED DRUG;

EID: 84857135712     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1120238109     Document Type: Article
Times cited : (877)

References (50)
  • 1
    • 0036557819 scopus 로고    scopus 로고
    • Why and how antibiotics are used in swine production
    • Cromwell GL (2002) Why and how antibiotics are used in swine production. Anim Biotechnol 13:7-27.
    • (2002) Anim Biotechnol , vol.13 , pp. 7-27
    • Cromwell, G.L.1
  • 2
    • 18944406651 scopus 로고    scopus 로고
    • Antibiotic growth promoters in agriculture: History and mode of action
    • Dibner JJ, Richards JD (2005) Antibiotic growth promoters in agriculture: History and mode of action. Poult Sci 84:634-643. (Pubitemid 40697362)
    • (2005) Poultry Science , vol.84 , Issue.4 , pp. 634-643
    • Dibner, J.J.1    Richards, J.D.2
  • 4
    • 0017811905 scopus 로고
    • Emergence of antibiotic-resistant bacteria in the intestinal flora of farm inhabitants
    • Levy SB (1978) Emergence of antibiotic-resistant bacteria in the intestinal flora of farm inhabitants. J Infect Dis 137:689-690.
    • (1978) J Infect Dis , vol.137 , pp. 689-690
    • Levy, S.B.1
  • 5
    • 0032726165 scopus 로고    scopus 로고
    • The effects of antibiotic usage in food animals on the development of antimicrobial resistance of importance for humans in Campylobacter and Escherichia coli
    • Aarestrup FM, Wegener HC (1999) The effects of antibiotic usage in food animals on the development of antimicrobial resistance of importance for humans in Campylobacter and Escherichia coli. Microbes Infect 1:639-644.
    • (1999) Microbes Infect , vol.1 , pp. 639-644
    • Aarestrup, F.M.1    Wegener, H.C.2
  • 6
    • 77949568092 scopus 로고    scopus 로고
    • Call of the wild: Antibiotic resistance genes in natural environments
    • Allen HK, et al. (2010) Call of the wild: Antibiotic resistance genes in natural environments. Nat Rev Microbiol 8:251-259.
    • (2010) Nat Rev Microbiol , vol.8 , pp. 251-259
    • Allen, H.K.1
  • 7
    • 69549086653 scopus 로고    scopus 로고
    • Functional characterization of the antibiotic resistance reservoir in the human microflora
    • Sommer MO, Dantas G, Church GM (2009) Functional characterization of the antibiotic resistance reservoir in the human microflora. Science 325:1128-1131.
    • (2009) Science , vol.325 , pp. 1128-1131
    • Sommer, M.O.1    Dantas, G.2    Church, G.M.3
  • 8
    • 57549107144 scopus 로고    scopus 로고
    • A global view of antibiotic resistance
    • Martinez JL, et al. (2009) A global view of antibiotic resistance. FEMS Microbiol Rev 33:44-65.
    • (2009) FEMS Microbiol Rev , vol.33 , pp. 44-65
    • Martinez, J.L.1
  • 10
    • 0342460609 scopus 로고    scopus 로고
    • Why are antibiotic resistance genes so resistant to elimination?
    • Salyers AA, Amábile-Cuevas CF (1997) Why are antibiotic resistance genes so resistant to elimination? Antimicrob Agents Chemother 41:2321-2325. (Pubitemid 27467534)
    • (1997) Antimicrobial Agents and Chemotherapy , vol.41 , Issue.11 , pp. 2321-2325
    • Salyers, A.A.1    Amabile-Cuevas, C.F.2
  • 11
    • 82955194467 scopus 로고    scopus 로고
    • Persistence of antibiotic resistance: Evaluation of a probiotic approach using antibiotic-sensitive Megasphaera elsdenii strains to prevent colonization of swine by antibiotic-resistant strains
    • Stanton TB, Humphrey SB (2011) Persistence of antibiotic resistance: Evaluation of a probiotic approach using antibiotic-sensitive Megasphaera elsdenii strains to prevent colonization of swine by antibiotic-resistant strains. Appl EnvironMicrobiol 77:7158-7166.
    • (2011) Appl EnvironMicrobiol , vol.77 , pp. 7158-7166
    • Stanton, T.B.1    Humphrey, S.B.2
  • 12
    • 82955169517 scopus 로고    scopus 로고
    • Chlortetracycline-resistant intestinal bacteria in organically raised and feral Swine
    • Stanton TB, Humphrey SB, Stoffregen WC (2011) Chlortetracycline-resistant intestinal bacteria in organically raised and feral Swine. Appl Environ Microbiol 77:7167-7170.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 7167-7170
    • Stanton, T.B.1    Humphrey, S.B.2    Stoffregen, W.C.3
  • 13
    • 47749155981 scopus 로고    scopus 로고
    • Antibiotics and antibiotic resistance genes in natural environments
    • Martínez JL (2008) Antibiotics and antibiotic resistance genes in natural environments. Science 321:365-367.
    • (2008) Science , vol.321 , pp. 365-367
    • Martínez, J.L.1
  • 14
    • 84857134993 scopus 로고    scopus 로고
    • US Department of Health and Human Services, and Center for Veterinary Medicine Draft guidance #209. Available at Accessed October 12, 2010
    • US Department of Health and Human Services, Food and Drug Administration, and Center for Veterinary Medicine (2010) Draft guidance #209. Available at http://www.fda.gov/downloads/animalveterinary/guidancecomplianceenforcement/ guidanceforindustry/ucm216936.pdf. Accessed October 12, 2010.
    • (2010)
  • 16
    • 4544359260 scopus 로고    scopus 로고
    • Molecular microbial ecology of the gastrointestinal tract: From phylogeny to function
    • Zoetendal EG, Cheng B, Koike S, Mackie RI (2004) Molecular microbial ecology of the gastrointestinal tract: From phylogeny to function. Curr Issues Intest Microbiol 5:31-47.
    • (2004) Curr Issues Intest Microbiol , vol.5 , pp. 31-47
    • Zoetendal, E.G.1    Cheng, B.2    Koike, S.3    Mackie, R.I.4
  • 17
    • 35448965272 scopus 로고    scopus 로고
    • Transfer of an ampicillin resistance gene between two Escherichia coli strains in the bowel microbiota of an infant treated with antibiotics
    • DOI 10.1093/jac/dkm327
    • Karami N, et al. (2007) Transfer of an ampicillin resistance gene between two Escherichia coli strains in the bowel microbiota of an infant treated with antibiotics. J Antimicrob Chemother 60:1142-1145. (Pubitemid 47617767)
    • (2007) Journal of Antimicrobial Chemotherapy , vol.60 , Issue.5 , pp. 1142-1145
    • Karami, N.1    Martner, A.2    Enne, V.I.3    Swerkersson, S.4    Adlerberth, I.5    Wold, A.E.6
  • 18
    • 0035142427 scopus 로고    scopus 로고
    • Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon
    • DOI 10.1128/AEM.67.2.561-568.2001
    • Shoemaker NB, Vlamakis H, Hayes K, Salyers AA (2001) Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon. Appl Environ Microbiol 67:561-568. (Pubitemid 32121342)
    • (2001) Applied and Environmental Microbiology , vol.67 , Issue.2 , pp. 561-568
    • Shoemaker, N.B.1    Vlamakis, H.2    Hayes, K.3    Salyers, A.A.4
  • 19
    • 0036642409 scopus 로고    scopus 로고
    • Evidence of extensive interspecies transfer of integron-mediated antimicrobial resistance genes among multidrug-resistant Enterobacteriaceae in a clinical setting
    • DOI 10.1086/341078
    • Leverstein-van Hall MA, et al. (2002) Evidence of extensive interspecies transfer of integron-mediated antimicrobial resistance genes among multidrug-resistant Enterobacteriaceae in a clinical setting. J Infect Dis 186:49-56. (Pubitemid 34666913)
    • (2002) Journal of Infectious Diseases , vol.186 , Issue.1 , pp. 49-56
    • Leverstein-Van, H.M.A.1    Box, A.T.A.2    Blok, H.E.M.3    Paauw, A.4    Fluit, A.C.5    Verhoef, J.6
  • 20
    • 0033068947 scopus 로고    scopus 로고
    • Evidence for recent intergeneric transfer of a new tetracycline resistance gene, tet(W), isolated from Butyrivibrio fibrisolvens, and the occurrence of tet(O) in ruminai bacteria
    • Barbosa TM, Scott KP, Flint HJ (1999) Evidence for recent intergeneric transfer of a new tetracycline resistance gene, tet(W), isolated from Butyrivibrio fibrisolvens, and the occurrence of tet(O) in ruminal bacteria. Environ Microbiol 1:53-64. (Pubitemid 129640028)
    • (1999) Environmental Microbiology , vol.1 , Issue.1 , pp. 53-64
    • Barbosa, T.M.1    Scott, K.P.2    Flint, H.J.3
  • 21
    • 0037479815 scopus 로고    scopus 로고
    • Isolation of tetracycline-resistant Megasphaera elsdenii strains with novel mosaic gene combinations of tet(O) and tet(W) from swine
    • DOI 10.1128/AEM.69.7.3874-3882.2003
    • Stanton TB, Humphrey SB (2003) Isolation of tetracycline-resistant Megasphaera elsdenii strains with novel mosaic gene combinations of tet(O) and tet(W) from swine. Appl Environ Microbiol 69:3874-3882. (Pubitemid 36870042)
    • (2003) Applied and Environmental Microbiology , vol.69 , Issue.7 , pp. 3874-3882
    • Stanton, T.B.1    Humphrey, S.B.2
  • 22
    • 78649387692 scopus 로고    scopus 로고
    • Tetracycline resistance associated with commensal bacteria from representative ready-to-consume deli and restaurant foods
    • Li X, Wang HH (2010) Tetracycline resistance associated with commensal bacteria from representative ready-to-consume deli and restaurant foods. J Food Prot 73:1841-1848.
    • (2010) J Food Prot , vol.73 , pp. 1841-1848
    • Li, X.1    Wang, H.H.2
  • 26
    • 74349110379 scopus 로고    scopus 로고
    • Using the metagenomics RAST server (MG-RAST) for analyzing shotgun metagenomes
    • pdb prot5368. Available at
    • Glass EM, Wilkening J, Wilke A, Antonopoulos D, Meyer F (2010) Using the metagenomics RAST server (MG-RAST) for analyzing shotgun metagenomes. Cold Spring Harb Protoc 2010:pdb prot5368. Available at http://cshprotocols.cshlp. org/.
    • (2010) Cold Spring Harb Protoc , vol.2010
    • Glass, E.M.1    Wilkening, J.2    Wilke, A.3    Antonopoulos, D.4    Meyer, F.5
  • 27
    • 58149183697 scopus 로고    scopus 로고
    • ARDB-Antibiotic Resistance Genes Database
    • Liu B, Pop M (2009) ARDB-Antibiotic Resistance Genes Database. Nucleic Acids Res 37(Database issue):D443-D447.
    • (2009) Nucleic Acids Res , vol.37 , Issue.DATABASE ISSUE
    • Liu, B.1    Pop, M.2
  • 28
    • 0034774482 scopus 로고    scopus 로고
    • Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens
    • DOI 10.1128/AAC.45.11.3246-3249.2001
    • MelvilleCM, ScottKP,Mercer DK, FlintHJ (2001)Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens. Antimicrob Agents Chemother 45:3246-3249. (Pubitemid 32988864)
    • (2001) Antimicrobial Agents and Chemotherapy , vol.45 , Issue.11 , pp. 3246-3249
    • Melville, C.M.1    Scott, K.P.2    Mercer, D.K.3    Flint, H.J.4
  • 29
    • 67650486955 scopus 로고    scopus 로고
    • The role of natural environments in the evolution of resistance traits in pathogenic bacteria
    • Martinez JL (2009) The role of natural environments in the evolution of resistance traits in pathogenic bacteria. Proc Biol Sci 276:2521-2530.
    • (2009) Proc Biol Sci , vol.276 , pp. 2521-2530
    • Martinez, J.L.1
  • 30
    • 65549165914 scopus 로고    scopus 로고
    • What antimicrobial resistance has taught us about horizontal gene transfer
    • Barlow M (2009) What antimicrobial resistance has taught us about horizontal gene transfer. Methods Mol Biol 532:397-411.
    • (2009) Methods Mol Biol , vol.532 , pp. 397-411
    • Barlow, M.1
  • 32
    • 0023298190 scopus 로고
    • Molecular mechanisms for transposition of drug-resistance genes and other movable genetic elements
    • Lupski JR (1987) Molecular mechanisms for transposition of drug-resistance genes and other movable genetic elements. Rev Infect Dis 9:357-368.
    • (1987) Rev Infect Dis , vol.9 , pp. 357-368
    • Lupski, J.R.1
  • 33
    • 79953170241 scopus 로고    scopus 로고
    • Effect of antibiotic treatment on the intestinal metabolome
    • Antunes LC, et al. (2011) Effect of antibiotic treatment on the intestinal metabolome. Antimicrob Agents Chemother 55:1494-1503.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1494-1503
    • Antunes, L.C.1
  • 34
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • DOI 10.1038/nature05414, PII NATURE05414
    • Turnbaugh PJ, et al. (2006) An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444:1027-1031. (Pubitemid 46018515)
    • (2006) Nature , vol.444 , Issue.7122 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 35
    • 66549102207 scopus 로고    scopus 로고
    • Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation
    • Antonopoulos DA, et al. (2009) Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation. Infect Immun 77:2367-2375.
    • (2009) Infect Immun , vol.77 , pp. 2367-2375
    • Antonopoulos, D.A.1
  • 36
    • 77955245068 scopus 로고    scopus 로고
    • Metronidazole effects on microbiota and mucus layer thickness in the rat gut
    • Pélissier MA, et al. (2010) Metronidazole effects on microbiota and mucus layer thickness in the rat gut. FEMS Microbiol Ecol 73:601-610.
    • (2010) FEMS Microbiol Ecol , vol.73 , pp. 601-610
    • Pélissier, M.A.1
  • 37
    • 78649266096 scopus 로고    scopus 로고
    • Reshaping the gut microbiome with bacterial transplantation and antibiotic intake
    • Manichanh C, et al. (2010) Reshaping the gut microbiome with bacterial transplantation and antibiotic intake. Genome Res 20:1411-1419.
    • (2010) Genome Res , vol.20 , pp. 1411-1419
    • Manichanh, C.1
  • 39
    • 56849106496 scopus 로고    scopus 로고
    • Thepervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
    • Dethlefsen L, Huse S, SoginML, RelmanDA(2008) Thepervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biol 6:e280.
    • (2008) PLoS Biol , vol.6
    • Dethlefsen, L.1    Huse, S.2    Sogin, M.L.3    Relman, D.A.4
  • 40
    • 77954672686 scopus 로고    scopus 로고
    • Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women
    • Santacruz A, et al. (2010) Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women. Br J Nutr 104:83-92.
    • (2010) Br J Nutr , vol.104 , pp. 83-92
    • Santacruz, A.1
  • 43
    • 58149200948 scopus 로고    scopus 로고
    • The Ribosomal Database Project: Improved alignments and new tools for rRNA analysis
    • Cole JR, et al. (2009) The Ribosomal Database Project: Improved alignments and new tools for rRNA analysis. Nucleic Acids Res 37(Database issue):D141-D145.
    • (2009) Nucleic Acids Res , vol.37 , Issue.DATABASE ISSUE
    • Cole, J.R.1
  • 44
    • 72949107142 scopus 로고    scopus 로고
    • Introducing mothur: Open-source, platform-independent, community-supported software for describing and comparing microbial communities
    • Schloss PD, et al. (2009) Introducing mothur: Open-source, platform-independent, community-supported software for describing and comparing microbial communities. Appl Environ Microbiol 75:7537-7541.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 7537-7541
    • Schloss, P.D.1
  • 45
    • 34748886657 scopus 로고    scopus 로고
    • PAST: Paleontological statistics software package for education and data analysis
    • Hammer ∅, Harper DAT
    • Hammer ∅, Harper DAT, Ryan PD (2001) PAST: Paleontological statistics software package for education and data analysis. Palaeontol Electronica 4:9.
    • (2001) Palaeontol Electronica , vol.4 , pp. 9
    • Ryan, P.D.1
  • 46
    • 70349993601 scopus 로고    scopus 로고
    • ShotgunFunctionalizeR: An R-package for functional comparison of metagenomes
    • Kristiansson E, Hugenholtz P, Dalevi D (2009) ShotgunFunctionalizeR: An R-package for functional comparison of metagenomes. Bioinformatics 25:2737-2738.
    • (2009) Bioinformatics , vol.25 , pp. 2737-2738
    • Kristiansson, E.1    Hugenholtz, P.2    Dalevi, D.3
  • 47
    • 45749127093 scopus 로고    scopus 로고
    • Developmentandexperimental validationofapredictive threshold cycle equation for quantification of virulence and marker genes by high-throughput nanoliter- Volume PCR on the OpenArray platform
    • Stedtfeld RD,etal. (2008)Developmentandexperimental validationofapredictive threshold cycle equation for quantification of virulence and marker genes by high-throughput nanoliter- volume PCR on the OpenArray platform. Appl Environ Microbiol 74:3831-3838.
    • (2008) Appl Environ Microbiol , vol.74 , pp. 3831-3838
    • Stedtfeld, R.D.1
  • 48
    • 34249939326 scopus 로고    scopus 로고
    • Biphenyl-utilizing bacteria and their functional genes in a pine root zone contaminated with polychlorinated biphenyls (PCBs)
    • DOI 10.1038/ismej.2007.26, PII ISMEJ200726
    • Leigh MB, et al. (2007) Biphenyl-utilizing bacteria and their functional genes in a pine root zone contaminated with polychlorinated biphenyls (PCBs). ISME J 1:134-148. (Pubitemid 46878156)
    • (2007) ISME Journal , vol.1 , Issue.2 , pp. 134-148
    • Leigh, M.B.1    Pellizari, V.H.2    Uhlik, O.3    Sutka, R.4    Rodrigues, J.5    Ostrom, N.E.6    Zhou, J.7    Tiedje, J.M.8
  • 49
    • 79953161283 scopus 로고    scopus 로고
    • Escherichia coli, enterococci, and Bacteroides thetaiotaomicron qPCR signals through wastewater and septage treatment
    • Srinivasan S, Aslan A, Xagoraraki I, Alocilja E, Rose JB (2011) Escherichia coli, enterococci, and Bacteroides thetaiotaomicron qPCR signals through wastewater and septage treatment. Water Res 45:2561-2572.
    • (2011) Water Res , vol.45 , pp. 2561-2572
    • Srinivasan, S.1    Aslan, A.2    Xagoraraki, I.3    Alocilja, E.4    Rose, J.B.5
  • 50
    • 33646827806 scopus 로고    scopus 로고
    • Multivariate dispersion as a measure of beta diversity
    • DOI 10.1111/j.1461-0248.2006.00926.x
    • Anderson MJ, Ellingsen KE, McArdle BH (2006) Multivariate dispersion as a measure of beta diversity. Ecol Lett 9:683-693. (Pubitemid 43773911)
    • (2006) Ecology Letters , vol.9 , Issue.6 , pp. 683-693
    • Anderson, M.J.1    Ellingsen, K.E.2    McArdle, B.H.3


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