Kinesin-2 family in vertebrate ciliogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 7, 2012, Pages 2388-2393

  Zhao, Chengtian ^a   Omori, Yoshihiro ^b   Brodowska, Katarzyna ^a   Kovach, Peter ^a   Malicki, Jarema ^a  

^a TUFTS UNIVERSITY   (United States)

^b OSAKA BIOSCIENCE INSTITUTE   (Japan)

Author keywords

Ciliary axoneme; Intraflagellar transport; Opsin; Outer segment

Indexed keywords

ETHYLNITROSOUREA; KINESIN 2; MESSENGER RNA; OPSIN; RETINA S ANTIGEN; TRANSDUCIN;

ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL STRUCTURE; CODON; CONTROLLED STUDY; EMBRYO; ENZYME SUBUNIT; EUKARYOTIC FLAGELLUM; GENE; GENE FUNCTION; GENE LOCUS; GENE OVEREXPRESSION; GENETIC CODE; HAIR CELL; HOMOZYGOSITY; MUTAGENESIS; MUTANT; NONHUMAN; OLFACTORY EPITHELIUM; PHENOTYPE; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA CONE; RETINA ROD; RNA INTERFERENCE; VERTEBRAL CANAL; ZEBRA FISH;

ANIMALS; BASE SEQUENCE; CILIA; DNA PRIMERS; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; KINESIN; MUTATION; POLYMERASE CHAIN REACTION; ZEBRAFISH;

ANIMALIA; DANIO RERIO; VERTEBRATA;

EID: 84857132738     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1116035109     Document Type: Article

References (40)

1. Rosenbaum JL, Witman GB (2002) Intraflagellar transport. Nat Rev Mol Cell Biol 3:813-825. (Pubitemid 35285272)
2. Satir P, Christensen ST (2007) Overview of structure and function of mammalian cilia. Annu Rev Physiol 69:377-400. (Pubitemid 46457649)
3. Lawrence CJ, et al. (2004) A standardized kinesin nomenclature. J Cell Biol 167:19-22. (Pubitemid 39363409)
4. Cole DG, et al. (1993) Novel heterotrimeric kinesin-related protein purified from sea urchin eggs. Nature 366:268-270. (Pubitemid 23359709)
5. Shakir MA, Fukushige T, Yasuda H, Miwa J, Siddiqui SS (1993) C. elegans osm-3 gene mediating osmotic avoidance behaviour encodes a kinesin-like protein. Neuroreport 4:891-894. (Pubitemid 23202242)
6. Walther Z, Vashishtha M, Hall JL (1994) The Chlamydomonas FLA10 gene encodes a novel kinesin-homologous protein. J Cell Biol 126:175-188. (Pubitemid 24214938)
7. Jana SC, Girotra M, Ray K (2011) Heterotrimeric kinesin-II is necessary and sufficient to promote different stepwise assembly of morphologically distinct bipartite cilia in Drosophila antenna. Mol Biol Cell 22:769-781.
8. Signor D, Wedaman KP, Rose LS, Scholey JM (1999) Two heteromeric kinesin complexes in chemosensory neurons and sensory cilia of Caenorhabditis elegans. Mol Biol Cell 10:345-360. (Pubitemid 29156477)
9. Yang Z, Goldstein LS (1998) Characterization of the KIF3C neural kinesin-like motor from mouse. Mol Biol Cell 9:249-261. (Pubitemid 28084122)
10. Muresan V, et al. (1998) KIF3C and KIF3A form a novel neuronal heteromeric kinesin that associates with membrane vesicles. Mol Biol Cell 9:637-652. (Pubitemid 28125622)
11. Insinna C, Pathak N, Perkins B, Drummond I, Besharse JC (2008) The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment development. Dev Biol 316:160-170.
12. Marszalek JR, Ruiz-Lozano P, Roberts E, Chien KR, Goldstein LS (1999) Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc Natl Acad Sci USA 96:5043-5048. (Pubitemid 29214532)
13. Nonaka S, et al. (1998) Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95:829-837. (Pubitemid 29014462)
14. Cano DA, Sekine S, HebrokM(2006) Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis. Gastroenterology 131:1856-1869. (Pubitemid 44958534)
15. Croyle MJ, et al. (2011) Role of epidermal primary cilia in the homeostasis of skin and hair follicles. Development 138:1675-1685.
16. Lin F, et al. (2003) Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci USA 100:5286-5291. (Pubitemid 36542697)
17. Rodieck RW (1973) The Vertebrate Retina. Principles of Structure and Function (W. H. Freeman, San Francisco).
18. Kennedy B, Malicki J (2009) What drives cell morphogenesis: A look inside the vertebrate photoreceptor. Dev Dyn 238:2115-2138.
19. Marszalek JR, et al. (2000) Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors. Cell 102:175-187.
20. Avasthi P, et al. (2009) Trafficking of membrane proteins to cone but not rod outer segments is dependent on heterotrimeric kinesin-II. J Neurosci 29:14287-14298.
21. Yamazaki H, Nakata T, Okada Y, Hirokawa N (1996) Cloning and characterization of KAP3: A novel kinesin superfamily-associated protein of KIF3A/3B. Proc Natl Acad Sci USA 93:8443-8448.
22. Yang Z, Roberts EA, Goldstein LS (2001) Functional analysis of mouse kinesin motor Kif3C. Mol Cell Biol 21:5306-5311. (Pubitemid 32702436)
23. Jimeno D, Lillo C, Roberts EA, Goldstein LS, Williams DS (2006) Kinesin-2 and photoreceptor cell death: requirement of motor subunits. Exp Eye Res 82:351-353. (Pubitemid 43122123)
24. Yin X, Takei Y, Kido MA, Hirokawa N (2011) Molecular motor KIF17 is fundamental for memory and learning via differential support of synaptic NR2A/2B levels. Neuron 70:310-325.
25. Tsujikawa M, Malicki J (2004) Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons. Neuron 42:703-716. (Pubitemid 38748786)
26. Omori Y, et al. (2008) Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8. Nat Cell Biol 10:437-444.
27. Malicki J, Avanesov A, Li J, Yuan S, Sun Z (2011) Analysis of cilia structure and function in zebrafish. Methods Cell Biol 101:39-74.
28. Doerre G, Malicki J (2002) Genetic analysis of photoreceptor cell development in the zebrafish retina. Mech Dev 110:125-138.
29. Zhao C, Malicki J (2011) Nephrocystins and MKS proteins interact with IFT particle and facilitate transport of selected ciliary cargos. EMBO J 30:2532-2544.
30. Snow JJ, et al. (2004) Two anterograde intraflagellar transport motors cooperate to build sensory cilia on C. elegans neurons. Nat Cell Biol 6:1109-1113. (Pubitemid 39468012)
31. Evans JE, et al. (2006) Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans. J Cell Biol 172:663-669.
32. Morsci NS, Barr MM (2011) Kinesin-3 KLP-6 regulates intraflagellar transport in male-specific cilia of Caenorhabditis elegans. Curr Biol 21:1239-1244.
33. Setou M, Nakagawa T, Seog DH, Hirokawa N (2000) Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science 288:1796-1802. (Pubitemid 30399012)
34. Guillaud L, Wong R, Hirokawa N (2008) Disruption of KIF17-Mint1 interaction by CaMKII-dependent phosphorylation: A molecular model of kinesin-cargo release. Nat Cell Biol 10:19-29.
35. Mukhopadhyay S, et al. (2007) Distinct IFT mechanisms contribute to the generation of ciliary structural diversity in C. elegans. EMBO J 26:2966-2980. (Pubitemid 46975773)
36. Ou G, Blacque OE, Snow JJ, Leroux MR, Scholey JM (2005) Functional coordination of intraflagellar transport motors. Nature 436:583-587. (Pubitemid 41112934)
37. Jenkins PM, et al. (2006) Ciliary targeting of olfactory CNG channels requires the CNGB1b subunit and the kinesin-2 motor protein, KIF17. Curr Biol 16:1211-1216. (Pubitemid 43867290)
38. Pugh E, Lamb T (2000) Phototransduction in vertebrate rods and cones. Handbook of Biological Physics (Elsevier, Amsterdam), Vol 3, pp 183-255.
39. Malicki J, et al. (1996) Mutations affecting development of the zebrafish retina. Development 123:263-273. (Pubitemid 27056753)
40. Malicki J (2000) Harnessing the power of forward genetics - analysis of neuronal diversity and patterning in the zebrafish retina. Trends Neurosci 23:531-541.