-
1
-
-
77954469348
-
Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii: resistance mechanisms and implications for therapy
-
Zavascki AP, Carvalhaes CG, Picão RC, Gales AC, (2010) Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii: resistance mechanisms and implications for therapy. Expert Rev Anti Infect Ther 8: 71-93.
-
(2010)
Expert Rev Anti Infect Ther
, vol.8
, pp. 71-93
-
-
Zavascki, A.P.1
Carvalhaes, C.G.2
Picão, R.C.3
Gales, A.C.4
-
2
-
-
33644504829
-
An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants
-
Liberati NT, Urbach JM, Miyata S, Lee DG, Drenkard E, et al. (2006) An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants. Proc Natl Acad Sci U S A 103: 2833-2838.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2833-2838
-
-
Liberati, N.T.1
Urbach, J.M.2
Miyata, S.3
Lee, D.G.4
Drenkard, E.5
-
3
-
-
34250692637
-
Inhibition of lysine biosynthesis: an evolving antibiotic strategy
-
Hutton CA, Perugini MA, Gerrard JA, (2007) Inhibition of lysine biosynthesis: an evolving antibiotic strategy. Mol Biosyst 3: 458-465.
-
(2007)
Mol Biosyst
, vol.3
, pp. 458-465
-
-
Hutton, C.A.1
Perugini, M.A.2
Gerrard, J.A.3
-
4
-
-
0242268400
-
Genetic requirements for mycobacterial survival during infection
-
Sassetti CM, Rubin EJ, (2003) Genetic requirements for mycobacterial survival during infection. Proc Natl Acad Sci U S A 100: 12989-12994.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12989-12994
-
-
Sassetti, C.M.1
Rubin, E.J.2
-
5
-
-
10344230938
-
Biosynthesis of diaminopimelate, the precursor of lysine and a component of peptidoglycan, is an essential function of Mycobacterium smegmatis
-
Pavelka MS Jr, Jacobs WR Jr, (1996) Biosynthesis of diaminopimelate, the precursor of lysine and a component of peptidoglycan, is an essential function of Mycobacterium smegmatis. J Bacteriol 178: 6496-6507.
-
(1996)
J Bacteriol
, vol.178
, pp. 6496-6507
-
-
Pavelka Jr., M.S.1
Jacobs Jr., W.R.2
-
6
-
-
33645030241
-
Robust Salmonella metabolism limits possibilities for new antimicrobials
-
Becker D, Selbach M, Rollenhagen C, Ballmaier M, Meyer TF, et al. (2006) Robust Salmonella metabolism limits possibilities for new antimicrobials. Nature 440: 303-307.
-
(2006)
Nature
, vol.440
, pp. 303-307
-
-
Becker, D.1
Selbach, M.2
Rollenhagen, C.3
Ballmaier, M.4
Meyer, T.F.5
-
8
-
-
0031012162
-
Reaction mechanism of Escherichia coli dihydrodipicolinate synthase investigated by X-ray crystallography and NMR spectroscopy
-
Blickling S, Renner C, Laber B, Pohlenz HD, Holak TA, et al. (1997) Reaction mechanism of Escherichia coli dihydrodipicolinate synthase investigated by X-ray crystallography and NMR spectroscopy. Biochemistry 36: 24-33.
-
(1997)
Biochemistry
, vol.36
, pp. 24-33
-
-
Blickling, S.1
Renner, C.2
Laber, B.3
Pohlenz, H.D.4
Holak, T.A.5
-
9
-
-
0028907826
-
The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 Å resolution
-
Mirwaldt C, Korndörfer I, Huber R, (1995) The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 Å resolution. J Mol Biol 246: 227-39.
-
(1995)
J Mol Biol
, vol.246
, pp. 227-239
-
-
Mirwaldt, C.1
Korndörfer, I.2
Huber, R.3
-
10
-
-
30344464699
-
Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution
-
Blagova E, Levdikov V, Milioti N, Fogg MJ, Kalliomaa AK, et al. (2006) Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution. Proteins 62: 297-301.
-
(2006)
Proteins
, vol.62
, pp. 297-301
-
-
Blagova, E.1
Levdikov, V.2
Milioti, N.3
Fogg, M.J.4
Kalliomaa, A.K.5
-
11
-
-
67349221170
-
Cloning and characterization of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis
-
Devenish SR, Huisman FH, Parker EJ, Hadfield AT, Gerrard JA, (2009) Cloning and characterization of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis. Biochim Biophys Acta 1794: 1168-74.
-
(2009)
Biochim Biophys Acta
, vol.1794
, pp. 1168-1174
-
-
Devenish, S.R.1
Huisman, F.H.2
Parker, E.J.3
Hadfield, A.T.4
Gerrard, J.A.5
-
12
-
-
25144446271
-
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance
-
Dobson RC, Griffin MD, Jameson GB, Gerrard JA, (2005) The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr D61: 1116-24.
-
(2005)
Acta Crystallogr
, vol.D61
, pp. 1116-1124
-
-
Dobson, R.C.1
Griffin, M.D.2
Jameson, G.B.3
Gerrard, J.A.4
-
13
-
-
79960467869
-
A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis
-
Evans G, Schuldt L, Griffin MD, Devenish SR, Grant Pearce F, et al. (2011) A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis. Arch Biochem Biophys 512: 154-9.
-
(2011)
Arch Biochem Biophys
, vol.512
, pp. 154-159
-
-
Evans, G.1
Schuldt, L.2
Griffin, M.D.3
Devenish, S.R.4
Grant Pearce, F.5
-
14
-
-
42449110007
-
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis
-
Kefala G, Evans GL, Griffin MD, Devenish SR, Pearce FG, et al. (2008) Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem J 411: 351-60.
-
(2008)
Biochem J
, vol.411
, pp. 351-360
-
-
Kefala, G.1
Evans, G.L.2
Griffin, M.D.3
Devenish, S.R.4
Pearce, F.G.5
-
15
-
-
33845229842
-
Dihydrodipicolinate synthase from Thermotoga maritima
-
Pearce FG, Perugini MA, McKerchar HJ, Gerrard JA, (2006) Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J 400: 359-66.
-
(2006)
Biochem J
, vol.400
, pp. 359-366
-
-
Pearce, F.G.1
Perugini, M.A.2
McKerchar, H.J.3
Gerrard, J.A.4
-
16
-
-
56349118584
-
Characterization and crystal structure of lysine insensitive Corynebacterium glutamicum dihydrodipicolinate synthase (cDHDPS) protein
-
Rice EA, Bannon GA, Glenn KC, Jeong SS, Sturman EJ, et al. (2008) Characterization and crystal structure of lysine insensitive Corynebacterium glutamicum dihydrodipicolinate synthase (cDHDPS) protein. Arch Biochem Biophys 480: 111-21.
-
(2008)
Arch Biochem Biophys
, vol.480
, pp. 111-121
-
-
Rice, E.A.1
Bannon, G.A.2
Glenn, K.C.3
Jeong, S.S.4
Sturman, E.J.5
-
17
-
-
77949314517
-
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax
-
Voss JE, Scally SW, Taylor NL, Atkinson SC, Griffin MD, et al. (2010) Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax. J Biol Chem 285: 5188-95.
-
(2010)
J Biol Chem
, vol.285
, pp. 5188-5195
-
-
Voss, J.E.1
Scally, S.W.2
Taylor, N.L.3
Atkinson, S.C.4
Griffin, M.D.5
-
18
-
-
55549137411
-
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen
-
Burgess BR, Dobson RC, Bailey MF, Atkinson SC, Griffin MD, et al. (2008) Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen. J Biol Chem 283: 27598-603.
-
(2008)
J Biol Chem
, vol.283
, pp. 27598-27603
-
-
Burgess, B.R.1
Dobson, R.C.2
Bailey, M.F.3
Atkinson, S.C.4
Griffin, M.D.5
-
19
-
-
48749085398
-
Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase
-
Girish TS, Sharma E, Gopal B, (2008) Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase. FEBS Lett 582: 2923-30.
-
(2008)
FEBS Lett
, vol.582
, pp. 2923-2930
-
-
Girish, T.S.1
Sharma, E.2
Gopal, B.3
-
20
-
-
79955835071
-
Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa
-
Kaur N, Gautam A, Kumar S, Singh A, Singh N, et al. (2011) Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa. Int J Biol Macromol 48: 779-787.
-
(2011)
Int J Biol Macromol
, vol.48
, pp. 779-787
-
-
Kaur, N.1
Gautam, A.2
Kumar, S.3
Singh, A.4
Singh, N.5
-
21
-
-
67649444194
-
Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis
-
Dobson RC, Perugini MA, Jameson GB, Gerrard JA, (2009) Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis. Biochimie 91: 1036-1044.
-
(2009)
Biochimie
, vol.91
, pp. 1036-1044
-
-
Dobson, R.C.1
Perugini, M.A.2
Jameson, G.B.3
Gerrard, J.A.4
-
22
-
-
25444488497
-
Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase
-
Dobson RC, Devenish SR, Turner LA, Clifford VR, Pearce FG, et al. (2005) Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase. Biochemistry 44: 13007-13013.
-
(2005)
Biochemistry
, vol.44
, pp. 13007-13013
-
-
Dobson, R.C.1
Devenish, S.R.2
Turner, L.A.3
Clifford, V.R.4
Pearce, F.G.5
-
23
-
-
77953544755
-
How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
-
Soares da Costa TP, Muscroft-Taylor AC, Dobson RC, Devenish SR, Jameson GB, et al. (2010) How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie 92: 837-845.
-
(2010)
Biochimie
, vol.92
, pp. 837-845
-
-
Soares da Costa, T.P.1
Muscroft-Taylor, A.C.2
Dobson, R.C.3
Devenish, S.R.4
Jameson, G.B.5
-
24
-
-
0022993447
-
Studies on the active site of succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase. Characterization using analogs of tetrahydrodipicolinate
-
Berges DA, DeWolf WE Jr, Dunn GL, Newman DJ, Schmidt SJ, et al. (1986) Studies on the active site of succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase. Characterization using analogs of tetrahydrodipicolinate. J Biol Chem 261: 6160-6167.
-
(1986)
J Biol Chem
, vol.261
, pp. 6160-6167
-
-
Berges, D.A.1
DeWolf Jr., W.E.2
Dunn, G.L.3
Newman, D.J.4
Schmidt, S.J.5
-
25
-
-
39649099147
-
Structure of Escherichia coli tetrahydrodipicolinate N-succinyltransferase reveals the role of a conserved C-terminal helix in cooperative substrate binding
-
Nguyen L, Kozlov G, Gehring K, (2008) Structure of Escherichia coli tetrahydrodipicolinate N-succinyltransferase reveals the role of a conserved C-terminal helix in cooperative substrate binding. FEBS Lett 582: 623-626.
-
(2008)
FEBS Lett
, vol.582
, pp. 623-626
-
-
Nguyen, L.1
Kozlov, G.2
Gehring, K.3
-
26
-
-
67349208429
-
The three-dimensional Structure of a mycobacterial DapD provides insights into DapD diversity and reveals unexpected particulars about the enzymatic mechanism
-
Schuldt L, Weyand S, Kefala G, Weiss MS, (2009) The three-dimensional Structure of a mycobacterial DapD provides insights into DapD diversity and reveals unexpected particulars about the enzymatic mechanism. J Mol Biol 389: 863-879.
-
(2009)
J Mol Biol
, vol.389
, pp. 863-879
-
-
Schuldt, L.1
Weyand, S.2
Kefala, G.3
Weiss, M.S.4
-
27
-
-
0031026466
-
Three-dimensional structure of tetrahydrodipicolinate N-succinyltransferase
-
Beaman TW, Binder DA, Blanchard JS, Roderick SL, (1997) Three-dimensional structure of tetrahydrodipicolinate N-succinyltransferase. Biochemistry 36: 489-494.
-
(1997)
Biochemistry
, vol.36
, pp. 489-494
-
-
Beaman, T.W.1
Binder, D.A.2
Blanchard, J.S.3
Roderick, S.L.4
-
28
-
-
0032555280
-
The conformational change and active site structure of tetrahydrodipicolinate N-succinyltransferase
-
Beaman TW, Blanchard JS, Roderick SL, (1998) The conformational change and active site structure of tetrahydrodipicolinate N-succinyltransferase. Biochemistry 37: 10363-10369.
-
(1998)
Biochemistry
, vol.37
, pp. 10363-10369
-
-
Beaman, T.W.1
Blanchard, J.S.2
Roderick, S.L.3
-
29
-
-
0036130402
-
Acyl group specificity at the active site of tetrahydrodipicolinate N-succinyltransferase
-
Beaman TW, Vogel KW, Drueckhammer DG, Blanchard JS, Roderick SL, (2002) Acyl group specificity at the active site of tetrahydrodipicolinate N-succinyltransferase. Protein Sci 11: 974-979.
-
(2002)
Protein Sci
, vol.11
, pp. 974-979
-
-
Beaman, T.W.1
Vogel, K.W.2
Drueckhammer, D.G.3
Blanchard, J.S.4
Roderick, S.L.5
-
30
-
-
0029061955
-
An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosa
-
Schweizer HP, Hoang T, (1995) An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosa. Gene 158: 15-22.
-
(1995)
Gene
, vol.158
, pp. 15-22
-
-
Schweizer, H.P.1
Hoang, T.2
-
31
-
-
64549143788
-
An improved Escherichia coli donor strain for diparental mating
-
Thoma S, Schobert M, (2009) An improved Escherichia coli donor strain for diparental mating. FEMS Microbiol Lett 294: 127-132.
-
(2009)
FEMS Microbiol Lett
, vol.294
, pp. 127-132
-
-
Thoma, S.1
Schobert, M.2
-
32
-
-
0032575051
-
A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants
-
Hoang TT, Karkhoff-Schweizer RR, Kutchma AJ, Schweizer HP, (1998) A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Gene 212: 77-86.
-
(1998)
Gene
, vol.212
, pp. 77-86
-
-
Hoang, T.T.1
Karkhoff-Schweizer, R.R.2
Kutchma, A.J.3
Schweizer, H.P.4
-
33
-
-
0023607375
-
A mouse model of chronic pulmonary infection with Pseudomonas aeruginosa and Pseudomonas cepacia
-
Starke JR, Edwards MS, Langston C, Baker CJ, (1987) A mouse model of chronic pulmonary infection with Pseudomonas aeruginosa and Pseudomonas cepacia. Pediatric Research 22: 698-702.
-
(1987)
Pediatric Research
, vol.22
, pp. 698-702
-
-
Starke, J.R.1
Edwards, M.S.2
Langston, C.3
Baker, C.J.4
-
34
-
-
79953737180
-
Overview of the CCP4 suite and current developments
-
Winn MD, Ballard CC, Cowtan KD, Dodson EJ, Emsley P, et al. (2011) Overview of the CCP4 suite and current developments. Acta Crystallogr D67: 235-242.
-
(2011)
Acta Crystallogr
, vol.D67
, pp. 235-242
-
-
Winn, M.D.1
Ballard, C.C.2
Cowtan, K.D.3
Dodson, E.J.4
Emsley, P.5
-
35
-
-
74549194551
-
Molecular replacement with MOLREP
-
Vagin A, Teplyakov A, (2010) Molecular replacement with MOLREP. Acta Crystallogr D66: 22-25.
-
(2010)
Acta Crystallogr
, vol.D66
, pp. 22-25
-
-
Vagin, A.1
Teplyakov, A.2
-
36
-
-
0030924992
-
Refinement of macromolecular structures by the maximum-likelihood method
-
Murshudov GN, Vagin AA, Dodson EJ, (1997) Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D53: 240-255.
-
(1997)
Acta Crystallogr
, vol.D53
, pp. 240-255
-
-
Murshudov, G.N.1
Vagin, A.A.2
Dodson, E.J.3
-
37
-
-
45549122274
-
Evolution of quaternary structure in a homotetrameric enzyme
-
Griffin MD, Dobson RC, Pearce FG, Antonio L, Whitten AE, et al. (2008) Evolution of quaternary structure in a homotetrameric enzyme. J Mol Biol 380: 691-703.
-
(2008)
J Mol Biol
, vol.380
, pp. 691-703
-
-
Griffin, M.D.1
Dobson, R.C.2
Pearce, F.G.3
Antonio, L.4
Whitten, A.E.5
-
38
-
-
59649112349
-
Conditional Restraints: Restraining the free atoms in ARP/wARP
-
Mooij WT, Cohen SX, Joosten K, Murshudov GN, Perrakis A, (2009) Conditional Restraints: Restraining the free atoms in ARP/wARP. Structure 17: 183-189.
-
(2009)
Structure
, vol.17
, pp. 183-189
-
-
Mooij, W.T.1
Cohen, S.X.2
Joosten, K.3
Murshudov, G.N.4
Perrakis, A.5
-
39
-
-
77949535720
-
Features and development of Coot
-
Emsley P, Lohkamp B, Scott WG, Cowtan K, (2010) Features and development of Coot. Acta Crystallogr D66: 486-501.
-
(2010)
Acta Crystallogr
, vol.D66
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
-
40
-
-
74549178560
-
MolProbity: all-atom structure validation for macromolecular crystallography
-
Chen VB, Arendall WB 3rd, Headd JJ, Keedy DA, Immormino RM, et al. (2010) MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallogr D66: 12-21.
-
(2010)
Acta Crystallogr
, vol.D66
, pp. 12-21
-
-
Chen, V.B.1
Arendall 3rd, W.B.2
Headd, J.J.3
Keedy, D.A.4
Immormino, R.M.5
-
41
-
-
0033824470
-
DaliLite workbench for protein structure comparison
-
Holm L, Park J, (2000) DaliLite workbench for protein structure comparison. Bioinformatics 16: 566-567.
-
(2000)
Bioinformatics
, vol.16
, pp. 566-567
-
-
Holm, L.1
Park, J.2
-
42
-
-
34548232365
-
Inference of macromolecular assemblies from crystalline state
-
Krissinel E, Henrick K, (2007) Inference of macromolecular assemblies from crystalline state. J Mol Biol 372: 774-797.
-
(2007)
J Mol Biol
, vol.372
, pp. 774-797
-
-
Krissinel, E.1
Henrick, K.2
-
43
-
-
0030444352
-
The diverse world of coenzyme A binding proteins
-
Engel C, Wierenga R, (1996) The diverse world of coenzyme A binding proteins. Curr Opin Struct Biol 6: 790-797.
-
(1996)
Curr Opin Struct Biol
, vol.6
, pp. 790-797
-
-
Engel, C.1
Wierenga, R.2
-
44
-
-
0000268861
-
Calculation of an OMIT map
-
Bhat TN, (1988) Calculation of an OMIT map. J Appl Cryst 21: 279-281.
-
(1988)
J Appl Cryst
, vol.21
, pp. 279-281
-
-
Bhat, T.N.1
|