메뉴 건너뛰기




Volumn 81, Issue 5, 2012, Pages 449-457

The kinase Pyk2 is involved in renal fibrosis by means of mechanical stretch-induced growth factor expression in renal tubules

Author keywords

CTGF; mechanical stretch; Pyk2; renal fibrosis; TGF 1

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; FOCAL ADHESION KINASE 2; REACTIVE OXYGEN METABOLITE; RHO KINASE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84857116226     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.403     Document Type: Article
Times cited : (21)

References (39)
  • 1
    • 0026344049 scopus 로고
    • New insights into the consequences and mechanisms of renal impairment in obstructive nephropathy
    • Klahr S. New insights into the consequences and mechanisms of renal impairment in obstructive nephropathy. Am J Kidney Dis 1991; 18: 689-699.
    • (1991) Am J Kidney Dis , vol.18 , pp. 689-699
    • Klahr, S.1
  • 2
    • 0028297144 scopus 로고
    • The pathophysiology of obstructive nephropathy: The role of vasoactive compounds in the hemodynamic and structural abnormalities of the obstructed kidney
    • Klahr S, Pukerson ML. The pathophysiology of obstructive nephropathy: the role of vasoactive compounds in the hemodynamic and structural abnormalities of the obstructed kidney. Am J Kidney Dis 1994; 23: 219-223. (Pubitemid 24075314)
    • (1994) American Journal of Kidney Diseases , vol.23 , Issue.2 , pp. 219-223
    • Klahr, S.1    Purkerson, M.L.2
  • 3
    • 0030856007 scopus 로고    scopus 로고
    • Antioxidant expression in experimental hydronephrosis: Role of mechanical stretch and growth factors
    • Ricardo SD, Ding G, Eufemio M et al. Antioxidant expression in experimental hydronephrosis: role of mechanical stretch and growth factors. Am J Physiol 1997; 272: F789-F798.
    • (1997) Am J Physiol , vol.272
    • Ricardo, S.D.1    Ding, G.2    Eufemio, M.3
  • 6
    • 0028335995 scopus 로고
    • Macrophages, monocyte chemoattractant peptide-1, and TGF-beta 1 in experimental hydronephrosis
    • Diamond JR, Kees-Folts D, Ding G et al. Macrophages, monocyte chemoattractant peptide-1, and TGF-beta 1 in experimental hydronephrosis. Am J Physiol 1994; 266: F926-F933.
    • (1994) Am J Physiol , vol.266
    • Diamond, J.R.1    Kees-Folts, D.2    Ding, G.3
  • 7
    • 0028233556 scopus 로고
    • Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney
    • Kaneto H, Morrissey J, McCracken R et al. Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney. Kidney Int 1994; 45: 1637-1647. (Pubitemid 24207499)
    • (1994) Kidney International , vol.45 , Issue.6 , pp. 1637-1647
    • Kaneto, H.1    Morrissey, J.2    McCracken, R.3    Reyes, A.4    Klahr, S.5
  • 8
    • 0026794233 scopus 로고
    • Renal function after release of ureteral obstruction: Role of endothelin and the renal artery endothelium
    • Reyes AA, Klahr S. Renal function after release of ureteral obstruction: role of endothelin and the renal artery endothelium. Kidney Int 1992; 42: 632-638.
    • (1992) Kidney Int , vol.42 , pp. 632-638
    • Reyes, A.A.1    Klahr, S.2
  • 9
    • 0027165757 scopus 로고
    • Increased expression of TGF-β1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation
    • Kaneto H, Morrissey J, Klahr S. Increased expression of TGF-beta 1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation. Kidney Int 1993; 44: 313-321. (Pubitemid 23228685)
    • (1993) Kidney International , vol.44 , Issue.2 , pp. 313-321
    • Kaneto, H.1    Morrissey, J.2    Klahr, S.3
  • 10
    • 0029154733 scopus 로고
    • Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions
    • Lev S, Moreno H, Martinez R et al. Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. Nature 1995; 376: 737-745.
    • (1995) Nature , vol.376 , pp. 737-745
    • Lev, S.1    Moreno, H.2    Martinez, R.3
  • 11
    • 0034002462 scopus 로고    scopus 로고
    • RAFTK/Pyk2-mediated cellular signalling
    • DOI 10.1016/S0898-6568(99)00076-5, PII S0898656899000765
    • Avraham H, Park SY, Schinkmann K et al. RAFTK/Pyk2-mediated cellular signalling. Cell Signal 2000; 12: 123-133. (Pubitemid 30126029)
    • (2000) Cellular Signalling , vol.12 , Issue.3 , pp. 123-133
    • Avraham, H.1    Park, S.-Y.2    Schinkmann, K.3    Avraham, S.4
  • 12
    • 0029096541 scopus 로고
    • Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily
    • Sasaki H, Nagura K, Ishino M et al. Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily. J Biol Chem 1995; 270: 21206-21219.
    • (1995) J Biol Chem , vol.270 , pp. 21206-21219
    • Sasaki, H.1    Nagura, K.2    Ishino, M.3
  • 14
    • 49949084432 scopus 로고    scopus 로고
    • Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction
    • Quinlan MR, Docherty NG, Watson RW et al. Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction. Am J Physiol Renal Physiol 2008; 295: F1-F11.
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Quinlan, M.R.1    Docherty, N.G.2    Watson, R.W.3
  • 15
    • 0029907265 scopus 로고    scopus 로고
    • A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
    • DOI 10.1038/383547a0
    • Dikic I, Tokiwa G, Lev S et al. A role for Pyk2 and Src in linking G-proteincoupled receptors with MAP kinase activation. Nature 1996; 383: 547-550. (Pubitemid 26346184)
    • (1996) Nature , vol.383 , Issue.6600 , pp. 547-550
    • Dikic, I.1    Tokiwa, G.2    Lev, S.3    Courtneidge, S.A.4    Schlessinger, J.5
  • 17
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • DOI 10.1172/JCI200319270
    • Sato M, Muragaki Y, Saika S et al. Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 2003; 112: 1486-1494. (Pubitemid 38056275)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.10 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3    Roberts, A.B.4    Ooshima, A.5
  • 20
    • 0033789980 scopus 로고    scopus 로고
    • Interaction of nitric oxide and transforming growth factor-beta1 induced by angiotensin II and mechanical stretch in rat renal tubular epithelial cells
    • Miyajima A, Chen J, Kirman I et al. Interaction of nitric oxide and transforming growth factor-beta1 induced by angiotensin II and mechanical stretch in rat renal tubular epithelial cells. J Urol 2000; 164: 1729-1734.
    • (2000) J Urol , vol.164 , pp. 1729-1734
    • Miyajima, A.1    Chen, J.2    Kirman, I.3
  • 21
    • 0033581897 scopus 로고    scopus 로고
    • RAFTK/PYK2-dependent and-independent apoptosis in multiple myeloma cells
    • Chauhan D, Hideshima T, Pandey P et al. RAFTK/PYK2-dependent and-independent apoptosis in multiple myeloma cells. Oncogene 1999; 18: 6733-6740.
    • (1999) Oncogene , vol.18 , pp. 6733-6740
    • Chauhan, D.1    Hideshima, T.2    Pandey, P.3
  • 22
    • 34548204415 scopus 로고    scopus 로고
    • Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival: Evidence for inside-out signaling leading to anoikis
    • DOI 10.1074/jbc.M611435200
    • Plotkin LI, Manolagas SC, Bellido T. Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis. J Biol Chem 2007; 282: 24120-24130. (Pubitemid 47328056)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.33 , pp. 24120-24130
    • Plotkin, L.I.1    Manolagas, S.C.2    Bellido, T.3
  • 23
    • 0029770721 scopus 로고    scopus 로고
    • Activation of Pyk2 by stress signals and coupling with JNK signaling pathway
    • Tokiwa G, Dikic I, Lev S et al. Activation of Pyk2 by stress signals and coupling with JNK signaling pathway. Science 1996; 273: 792-794. (Pubitemid 26271523)
    • (1996) Science , vol.273 , Issue.5276 , pp. 792-794
    • Tokiwa, G.1    Dikic, I.2    Lev, S.3    Schlessinger, J.4
  • 24
    • 0037073719 scopus 로고    scopus 로고
    • Cyclic strain activates redox-sensitive proline-rich tyrosine kinase 2 (PYK2) in endothelial cells
    • DOI 10.1074/jbc.M110937200
    • Cheng JJ, Chao YJ, Wang DL. Cyclic strain activates redox-sensitive proline-rich tyrosine kinase 2 (PYK2) in endothelial cells. J Biol Chem 2002; 277: 48152-48157. (Pubitemid 35470764)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.50 , pp. 48152-48157
    • Cheng, J.-J.1    Chao, Y.-J.2    Wang, D.L.3
  • 25
    • 77957801973 scopus 로고    scopus 로고
    • Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes
    • Lysechko TL, Cheung SM, Ostergaard HL. Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes. J Biol Chem 2010; 285: 31174-31184.
    • (2010) J Biol Chem , vol.285 , pp. 31174-31184
    • Lysechko, T.L.1    Cheung, S.M.2    Ostergaard, H.L.3
  • 26
    • 66149096117 scopus 로고    scopus 로고
    • Stretch-activated channel activation promotes early after depolarizations in rat ventricular myocytes under oxidative stress
    • Wang Y, Joyner RW, Wagner MB et al. Stretch-activated channel activation promotes early after depolarizations in rat ventricular myocytes under oxidative stress. Am J Physiol Heart Circ Physiol 2009; 296: H1227-H1235.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Wang, Y.1    Joyner, R.W.2    Wagner, M.B.3
  • 28
    • 52449128009 scopus 로고    scopus 로고
    • Mechanism of dietary salt-mediated increase in intravascular production of TGF-beta1
    • Ying WZ, Aaron K, Sanders PW. Mechanism of dietary salt-mediated increase in intravascular production of TGF-beta1. Am J Physiol Renal Physiol 2008; 295: F406-F414.
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Ying, W.Z.1    Aaron, K.2    Sanders, P.W.3
  • 29
    • 0026515835 scopus 로고
    • Effects of transforming growth factor-beta on collagen synthesis by normal rat kidney epithelial cells
    • Creely JJ, DiMari SJ, Howe AM et al. Effects of transforming growth factor-beta on collagen synthesis by normal rat kidney epithelial cells. Am J Pathol 1992; 140: 45-55.
    • (1992) Am J Pathol , vol.140 , pp. 45-55
    • Creely, J.J.1    Dimari, S.J.2    Howe, A.M.3
  • 31
    • 17344376055 scopus 로고    scopus 로고
    • Mechanotransduction: All signals point to cytoskeleton, matrix, and integrins
    • Alenghat FJ, Ingber DE. Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins. Sci STKE 2002; 2002: pe6.
    • (2002) Sci STKE , vol.2002
    • Alenghat, F.J.1    Ingber, D.E.2
  • 34
    • 70849136597 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF, CCN2) - A marker, mediator and therapeutic target for renal fibrosis
    • Phanish MK, Winn SK, Dockrell ME. Connective tissue growth factor (CTGF, CCN2)-a marker, mediator and therapeutic target for renal fibrosis. Nephron Exp Nephrol 2010; 114: e83-e92.
    • (2010) Nephron Exp Nephrol , vol.114
    • Phanish, M.K.1    Winn, S.K.2    Dockrell, M.E.3
  • 36
    • 33845242306 scopus 로고    scopus 로고
    • Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy
    • DOI 10.1681/ASN.2006050520
    • Tan X, Li Y, Liu Y. Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy. J Am Soc Nephrol 2006; 17: 3382-3393. (Pubitemid 44865281)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.12 , pp. 3382-3393
    • Tan, X.1    Li, Y.2    Liu, Y.3
  • 37
    • 35848934112 scopus 로고    scopus 로고
    • Quantification of renal pathology by image analysis
    • Rangan KG, Tesch GH. Quantification of renal pathology by image analysis. Nephrology 2007; 12: 553-558.
    • (2007) Nephrology , vol.12 , pp. 553-558
    • Rangan, K.G.1    Tesch, G.H.2
  • 39
    • 66749154806 scopus 로고    scopus 로고
    • Direct aldosterone action as a profibrotic factor via ROS-mediated SGK1 in peritoneal fibroblasts
    • Yamahara H, Kishimoto N, Nakata M et al. Direct aldosterone action as a profibrotic factor via ROS-mediated SGK1 in peritoneal fibroblasts. Kidney Blood Press Res 2009; 32: 185-193.
    • (2009) Kidney Blood Press Res , vol.32 , pp. 185-193
    • Yamahara, H.1    Kishimoto, N.2    Nakata, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.