Genotype- and mutation site-specific QT adaptation during exercise, recovery, and postural changes in children with long-QT syndrome

Circulation: Arrhythmia and Electrophysiology

Volumn 4, Issue 6, 2011, Pages 867-873

  Aziz, Peter F ^a   Wieand, Tammy S ^a   Ganley, Jamie ^a   Henderson, Jacqueline ^a   Patel, Akash R ^a   Iyer, V Ramesh ^a   Vogel, R Lee ^a   McBride, Michael ^a   Vetter, Victoria L ^a   Shah, Maully J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Exercise stress test; Ion channels; Long QT syndrome; Pediatrics

Indexed keywords

ARTICLE; BICYCLE ERGOMETER; CHILD; CLINICAL FEATURE; CONTROLLED STUDY; EXERCISE RECOVERY; EXERCISE TEST; FEMALE; GENOTYPE; HUMAN; LONG QT SYNDROME; LONG QT SYNDROME 1; LONG QT SYNDROME 2; MAJOR CLINICAL STUDY; MALE; PREDICTIVE VALUE; PRIORITY JOURNAL; QT INTERVAL; RR INTERVAL; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; SITE DIRECTED MUTAGENESIS; STANDING; SUPINE POSITION; ADAPTATION; ADOLESCENT; ADULT; AGE; BODY POSTURE; CONVALESCENCE; ELECTROCARDIOGRAPHY; EXERCISE; GENETIC PREDISPOSITION; GENETICS; MUTATION; PATHOPHYSIOLOGY; PHENOTYPE; PRESCHOOL CHILD; RETROSPECTIVE STUDY; TIME; UNITED STATES;

ERG1 POTASSIUM CHANNEL; KCNE1 PROTEIN, HUMAN; KCNE2 PROTEIN, HUMAN; KCNQ1 PROTEIN, HUMAN; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KCNQ1; SODIUM CHANNEL; SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA; VOLTAGE GATED POTASSIUM CHANNEL;

ADAPTATION, PHYSIOLOGICAL; ADOLESCENT; AGE FACTORS; CHILD; CHILD, PRESCHOOL; ELECTROCARDIOGRAPHY; ETHER-A-GO-GO POTASSIUM CHANNELS; EXERCISE; EXERCISE TEST; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KCNQ1 POTASSIUM CHANNEL; LONG QT SYNDROME; MALE; MUTATION; PHENOTYPE; PHILADELPHIA; POSTURE; POTASSIUM CHANNELS, VOLTAGE-GATED; PREDICTIVE VALUE OF TESTS; RECOVERY OF FUNCTION; RETROSPECTIVE STUDIES; ROMANO-WARD SYNDROME; SODIUM CHANNELS; TIME FACTORS; YOUNG ADULT;

EID: 84857069290     PISSN: 19413149     EISSN: 19413084     Source Type: Journal    
DOI: 10.1161/CIRCEP.111.963330     Document Type: Article

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