-
1
-
-
72149097863
-
Guide to receptors and channels, fourth ed
-
Alexander, S.P.H., Mathie, A., Peters, J.A., 2009. Guide to receptors and channels, fourth ed., Br. J. Pharmacol., 158 (Suppl. 1), S1-S254.
-
(2009)
Br. J. Pharmacol.
, vol.158
, Issue.SUPPL. 1
-
-
Alexander, S.P.H.1
Mathie, A.2
Peters, J.A.3
-
2
-
-
0028952746
-
Relaxant influence of phosphodiesterase inhibitors in the cat gastric fundus
-
A.J. Barbier, and R.A. Lefebvre Relaxant influence of phosphodiesterase inhibitors in the cat gastric fundus Eur. J. Pharmacol. 276 1995 41 47
-
(1995)
Eur. J. Pharmacol.
, vol.276
, pp. 41-47
-
-
Barbier, A.J.1
Lefebvre, R.A.2
-
3
-
-
0033005188
-
4 agonist, prucalopride, in healthy humans
-
4 agonist, prucalopride, in healthy humans Gut 44 1999 682 686 (Pubitemid 29195916)
-
(1999)
Gut
, vol.44
, Issue.5
, pp. 682-686
-
-
Bouras, E.P.1
Camilleri, M.2
Burton, D.D.3
McKinzie, S.4
-
4
-
-
0025259687
-
Activation of cyclic AMP-dependent protein kinase during canine lower esophageal sphincter relaxation
-
M.S. Barnette, M. Grous, T.J. Torphy, and H.S. Orsmbee III Activation of cyclic AMP-dependent protein kinase during canine lower esophageal sphincter relaxation J. Pharmacol. Exp. Ther. 252 1990 1160 1166 (Pubitemid 20127424)
-
(1990)
Journal of Pharmacology and Experimental Therapeutics
, vol.252
, Issue.3
, pp. 1160-1166
-
-
Barnette, M.S.1
Grous, M.2
Torphy, T.J.3
Ormsbee III, H.S.4
-
5
-
-
0027717012
-
Initial biochemical and functional characterization of cyclic nucleotide phosphodiesterase isozymes in canine colonic smooth muscle
-
M.S. Barnette, C.D. Manning, W.J. Price, and F.C. Barone Initial biochemical and functional characterization of cyclic nucleotide phosphodiesterase isozymes in canine colonic smooth muscle J. Pharmacol. Exp. Ther. 264 1993 801 812 (Pubitemid 24283544)
-
(1993)
Journal of Pharmacology and Experimental Therapeutics
, vol.264
, Issue.2
, pp. 801-812
-
-
Barnette, M.S.1
Manning, C.D.2
Price, W.J.3
Barone, F.C.4
-
6
-
-
0025215525
-
Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors
-
J.A. Beavo, and D.H. Reifsnyder Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors Trends Pharmacol. Sci. 11 1990 150 155 (Pubitemid 20118008)
-
(1990)
Trends in Pharmacological Sciences
, vol.11
, Issue.4
, pp. 150-155
-
-
Beavo, J.A.1
Reifsnyder, D.H.2
-
7
-
-
0035121508
-
Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder
-
E.P. Bouras, M. Camilleri, D.D. Burton, G. Thomforde, S. McKinzie, and A.R. Zinsmeister Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder Gastroenterology 120 2001 354 360 (Pubitemid 32147632)
-
(2001)
Gastroenterology
, vol.120
, Issue.2
, pp. 354-360
-
-
Bouras, E.P.1
Camilleri, M.2
Burton, D.D.3
Thomforde, G.4
McKinzie, S.5
Zinsmeister, A.R.6
-
8
-
-
44349130441
-
A placebo-controlled trial of prucalopride for severe chronic constipation
-
DOI 10.1056/NEJMoa0800670
-
M. Camilleri, R. Kerstens, A. Rykx, and L. Vandeplassche A placebo-controlled trial of prucalopride for severe chronic constipation N. Engl. J. Med. 358 2008 2344 2354 (Pubitemid 351749158)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.22
, pp. 2344-2354
-
-
Camilleri, M.1
Kerstens, R.2
Rykx, A.3
Vandeplassche, L.4
-
10
-
-
33746925213
-
4 receptor agonists enhance both cholinergic and nitrergic activities in human isolated colon circular muscle
-
DOI 10.1111/j.1365-2982.2006.00810.x
-
4 receptor agonists enhance both cholinergic and nitrergic activities in human isolated colon circular muscle Neurogastroenterol. Motil. 18 2006 853 861 (Pubitemid 44201172)
-
(2006)
Neurogastroenterology and Motility
, vol.18
, Issue.9
, pp. 853-861
-
-
Cellek, S.1
John, A.K.2
Thangiah, R.3
Dass, N.B.4
Bassil, A.K.5
Jarvie, E.M.6
Lalude, O.7
Vivekanandan, S.8
Sanger, G.J.9
-
12
-
-
33646758583
-
4 receptor agonists at gastric versus cardiac receptors: An operational framework to explain and quantify organ-specific behavior
-
DOI 10.1124/jpet.106.101329
-
J.H. De Maeyer, N.H. Prins, J.A.J. Schuurkes, and R.A. Lefebvre Differential effects of 5-hydroxytryptamine4 receptor agonists at gastric versus cardiac receptors: an operational framework to explain and quantify organ-specific behavior J. Pharmacol. Exp. Ther. 317 2006 955 964 (Pubitemid 43764097)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.317
, Issue.3
, pp. 955-964
-
-
De Maeyer, J.H.1
Prins, N.H.2
Schuurkes, J.A.J.3
Lefebvre, R.A.4
-
14
-
-
0031950380
-
Effect of a novel prokinetic drug, R093877, on gastrointestinal transit in healthy volunteers
-
A.V. Emmanuel, M.A. Kamm, A.J. Roy, and K. Antonelli Effect of a novel prokinetic drug, R093877, on gastrointestinal transit in healthy volunteers Gut 42 1998 511 516 (Pubitemid 28186568)
-
(1998)
Gut
, vol.42
, Issue.4
, pp. 511-516
-
-
Emmanuel, A.V.1
Kamm, M.A.2
Roy, A.J.3
Antonelli, K.4
-
17
-
-
33846347644
-
The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
-
DOI 10.1053/j.gastro.2006.11.002, PII S001650850602436X
-
M.D. Gershon, and J. Tack The serotonin signaling system: from basic understanding to drug development for functional GI disorders Gastroenterology 132 2007 397 414 (Pubitemid 46127672)
-
(2007)
Gastroenterology
, vol.132
, Issue.1
, pp. 397-414
-
-
Gershon, M.D.1
Tack, J.2
-
18
-
-
33847247864
-
7 receptor expression and function in the circular muscle of the human colon
-
DOI 10.1016/j.lfs.2006.12.025, PII S0024320507000288
-
7 receptor expression and function in the circular muscle of the human colon Life Sci. 80 2007 1198 1205 (Pubitemid 46329015)
-
(2007)
Life Sciences
, vol.80
, Issue.13
, pp. 1198-1205
-
-
Irving, H.R.1
Tan, Y.Y.2
Tochon-Danguy, N.3
Liu, H.4
Chetty, N.5
Desmond, P.V.6
Pouton, C.W.7
Coupar, I.M.8
-
20
-
-
77956925425
-
Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues
-
V. Lakics, E.H. Karran, and F.G. Boess Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues Neuropharmacology 59 2010 367 374
-
(2010)
Neuropharmacology
, vol.59
, pp. 367-374
-
-
Lakics, V.1
Karran, E.H.2
Boess, F.G.3
-
21
-
-
0035216303
-
2-agonist UK-14,304 on acetylcholine release in the pig gastric fundus
-
2-agonist UK-14,304 on acetylcholine release in the pig gastric fundus Neuropharmacology 40 2001 270 278
-
(2001)
Neuropharmacology
, vol.40
, pp. 270-278
-
-
Leclere, P.G.1
Lefebvre, R.A.2
-
22
-
-
0036152825
-
Presynaptic modulation of cholinergic neurotransmission in the human proximal stomach
-
P.G. Leclere, and R.A. Lefebvre Presynaptic modulation of cholinergic neurotransmission in the human proximal stomach Br. J. Pharmacol. 135 2002 135 142 (Pubitemid 34102107)
-
(2002)
British Journal of Pharmacology
, vol.135
, Issue.1
, pp. 135-142
-
-
Leclere, P.G.1
Lefebvre, R.A.2
-
24
-
-
0026042994
-
Responses of porcine gastric and duodenal smooth muscle to VIP
-
K. Mandrek, and K. Milenov Responses of porcine gastric and duodenal smooth muscle to VIP J. Auton. Pharmacol. 11 1991 353 364
-
(1991)
J. Auton. Pharmacol.
, vol.11
, pp. 353-364
-
-
Mandrek, K.1
Milenov, K.2
-
25
-
-
0042355363
-
Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system
-
DOI 10.1124/mol.64.3.533
-
D.H. Maurice, D. Palmer, D.G. Tilley, H.A. Dunkerley, S.J. Netherton, D.R. Raymond, H.S. Elbatarny, and S.L. Jimmo Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system Mol. Pharmacol. 64 2003 533 546 (Pubitemid 37048555)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.3
, pp. 533-546
-
-
Maurice, D.H.1
Palmer, D.2
Tilley, D.G.3
Dunkerley, H.A.4
Netherton, S.J.5
Raymond, D.R.6
Elbatarny, H.S.7
Jimmo, S.L.8
-
26
-
-
0023081945
-
The pig as a model for human nutrition
-
E.R. Miller, and D.E. Ullrey The pig as a model for human nutrition Annu. Rev. Nutr. 7 1987 361 382
-
(1987)
Annu. Rev. Nutr.
, vol.7
, pp. 361-382
-
-
Miller, E.R.1
Ullrey, D.E.2
-
27
-
-
0347595574
-
Effects of phosphodiesterase inhibitors on oesophageal neuromuscular functions
-
DOI 10.1046/j.1350-1925.2003.00444.x
-
H. Park, E. Clark, and J.L. Conklin Effects of phosphodiesterase inhibitors on oesophageal neuromuscular functions Neurogastroenterol. Motil. 15 2003 625 633 (Pubitemid 38030640)
-
(2003)
Neurogastroenterology and Motility
, vol.15
, Issue.6
, pp. 625-633
-
-
Park, H.1
Clark, E.2
Conklin, J.L.3
-
28
-
-
0033709510
-
5-HT(4) receptors on cholinergic nerves involved in contractility of canine and human large intestinal longitudinal muscle
-
N.H. Prins, L.M. Akkermans, R.A. Lefebvre, and J.A. Schuurkes 5-HT(4) receptors on cholinergic nerves involved in contractility of canine and human large intestinal longitudinal muscle Br. J. Pharmacol. 131 2000 927 932
-
(2000)
Br. J. Pharmacol.
, vol.131
, pp. 927-932
-
-
Prins, N.H.1
Akkermans, L.M.2
Lefebvre, R.A.3
Schuurkes, J.A.4
-
29
-
-
0035197085
-
Characterization of the receptors involved in the 5-HT-induced excitation of canine antral longitudinal muscle
-
N.H. Prins, L.M. Akkermans, R.A. Lefebvre, and J.A. Schuurkes Characterization of the receptors involved in the 5-HT-induced excitation of canine antral longitudinal muscle Br. J. Pharmacol. 134 2001 1351 1359 (Pubitemid 33097267)
-
(2001)
British Journal of Pharmacology
, vol.134
, Issue.6
, pp. 1351-1359
-
-
Prins, N.H.1
Akkermans, L.M.A.2
Lefebvre, R.A.3
Schuurkes, J.A.J.4
-
31
-
-
48249119680
-
4 receptor activation facilitates recovery from synaptic rundown and increases transmitter release from single varicosities of myenteric neurons
-
4 receptor activation facilitates recovery from synaptic rundown and increases transmitter release from single varicosities of myenteric neurons Am. J. Physiol. 294 2008 G1376 G1383
-
(2008)
Am. J. Physiol.
, vol.294
-
-
Ren, J.1
Zhou, X.2
Galligan, J.J.3
-
32
-
-
0030958762
-
CGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes
-
M. Rivet-Bastide, G. Vandecasteele, S. Hatem, I. Verde, A. Bénardeau, J.-J. Mercadier, and R. Fischmeister cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes J. Clin. Invest. 99 1997 2710 2718 (Pubitemid 27259818)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.11
, pp. 2710-2718
-
-
Rivet-Bastide, M.1
Vandecasteele, G.2
Hatem, S.3
Verde, I.4
Benardeau, A.5
Mercadier, J.-J.6
Fischmeister, R.7
-
33
-
-
0027251045
-
Gastrointestinal longitudinal muscle contractions
-
S.K. Sarna Gastrointestinal longitudinal muscle contractions Am. J. Physiol. 265 1993 G156 G164
-
(1993)
Am. J. Physiol.
, vol.265
-
-
Sarna, S.K.1
-
34
-
-
0034531342
-
4-induced contractions in passively sensitized human airways
-
D.T. Schmidt, N. Watson, G. Dent, E. Rühlman, D. Branscheid, H. Magnussen, and K.F. Rabe The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C4-induced contractions in passively sensitized human airways Br. J. Pharmacol. 131 2000 1607 1618 (Pubitemid 32056426)
-
(2000)
British Journal of Pharmacology
, vol.131
, Issue.8
, pp. 1607-1618
-
-
Schmidt, D.T.1
Watson, N.2
Dent, G.3
Ruhlmann, E.4
Branscheid, D.5
Magnussen, H.6
Rabe, K.F.7
-
35
-
-
70349941414
-
Immunohistochemical localization of phosphodiesterase 2A in multiple mammalian species
-
D.T. Stephenson, T.M. Coskran, M.B. Wilhelms, W.O. Adamowicz, M.M. O'Donnell, K.B. Muravnick, F.S. Menniti, R.J. Kleiman, and D. Morton Immunohistochemical localization of phosphodiesterase 2A in multiple mammalian species J. Histochem. Cytochem. 57 2009 933 949
-
(2009)
J. Histochem. Cytochem.
, vol.57
, pp. 933-949
-
-
Stephenson, D.T.1
Coskran, T.M.2
Wilhelms, M.B.3
Adamowicz, W.O.4
O'Donnell, M.M.5
Muravnick, K.B.6
Menniti, F.S.7
Kleiman, R.J.8
Morton, D.9
-
36
-
-
61649119045
-
Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives
-
J. Tack, M. Van Outryve, G. Beyens, R. Kerstens, and L. Vandeplassche Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives Gut 58 2009 357 365
-
(2009)
Gut
, vol.58
, pp. 357-365
-
-
Tack, J.1
Van Outryve, M.2
Beyens, G.3
Kerstens, R.4
Vandeplassche, L.5
-
37
-
-
0033004323
-
4 receptor distribution with cholinergic transmission in the guinea pig stomach
-
DOI 10.1016/S0014-2999(99)00321-0, PII S0014299999003210
-
4 receptor distribution with cholinergic transmission in the guinea pig stomach Eur. J. Pharmacol. 374 1999 489 494 (Pubitemid 29313462)
-
(1999)
European Journal of Pharmacology
, vol.374
, Issue.3
, pp. 489-494
-
-
Takada, K.1
Sakurai-Yamashita, Y.2
Yamashita, K.3
Kaibara, M.4
Hamada, Y.5
Nakane, Y.6
Hioki, K.7
Taniyama, K.8
-
38
-
-
0029786358
-
The effect of isoenzyme-selective PDE inhibitors on methacholine-induced contraction of guinea-pig and rat ileum
-
A. Tomkinson, and D. Raeburn The effect of isoenzyme-selective PDE inhibitors on metacholine-induced contraction of guinea-pig and rat ileum Br. J. Pharmacol. 118 1996 2131 2139 (Pubitemid 26292586)
-
(1996)
British Journal of Pharmacology
, vol.118
, Issue.8
, pp. 2131-2139
-
-
Tomkinson, A.1
Raeburn, D.2
-
39
-
-
0025756130
-
Role of cyclic nucleotide phosphodiesterase isozymes in intact canine trachealis
-
T.J. Torphy, H.-L. Zhou, M. Burman, and L.B.F. Huang Role of cyclic nucleotide phosphodiesterase isozymes in intact canine trachealis Mol. Pharmacol. 39 1991 376 384
-
(1991)
Mol. Pharmacol.
, vol.39
, pp. 376-384
-
-
Torphy, T.J.1
Zhou, H.-L.2
Burman, M.3
Huang, L.B.F.4
-
40
-
-
0031578230
-
Expression, purification, and characterization of human cAMP-specific phosphodiesterase (PDE4) subtypes A, B, C, and D
-
DOI 10.1006/bbrc.1997.6636
-
P. Wang, J.C. Myers, P. Wu, B. Cheewatrakoolpong, R.W. Egan, and M.M. Billah Expression, purification, and characterization of human cAMP-specific phosphodiesterase (PDE4) subtypes A, B, C, and D Biochem. Biophys. Res. Commun. 234 1997 320 324 (Pubitemid 27243900)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.234
, Issue.2
, pp. 320-324
-
-
Wang, P.1
Myers, J.G.2
Wu, P.3
Cheewatrakoolpong, B.4
Egan, R.W.5
Billah, M.M.6
-
41
-
-
0023449746
-
Stimulation of acetylcholine release from myenteric neurons of guinea pig small intestine by forskolin and cyclic AMP
-
W.M. Yau, J. Dorsett, and M.L. Youther Stimulation of acetylcholine release from myenteric neurons of guinea pig small intestine by forskolin and cyclic AMP J. Pharmacol. Exp. Ther. 243 1987 507 510
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.243
, pp. 507-510
-
-
Yau, W.M.1
Dorsett, J.2
Youther, M.L.3
-
42
-
-
0029872403
-
Potentiation of acetylcholine release from tracheal parasympathetic nerves by cAMP
-
X.-Y. Zhang, N.E. Robinson, and F.-X. Zhu Potentiation of acetylcholine release from tracheal parasympathetic nerves by cAMP Am. J. Physiol. 270 1996 L541 L546
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Zhang, X.-Y.1
Robinson, N.E.2
Zhu, F.-X.3
|