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Volumn 118, Issue 8, 1996, Pages 2131-2139

The effect of isoenzyme-selective PDE inhibitors on methacholine-induced contraction of guinea-pig and rat ileum

Author keywords

Cyclic AMP; Cyclic GMP; Enprofyll ine; Gastrointestinal smooth muscle; Ileum; PDE inhibitors; Rolipram; Siguazodan; Vinpocetine; Zaprinast

Indexed keywords

ENPROFYLLINE; ISOENZYME; ISOPRENALINE; METHACHOLINE; NITROPRUSSIDE SODIUM; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM; SIGUAZODAN; VINPOCETINE; ZAPRINAST;

EID: 0029786358     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15653.x     Document Type: Article
Times cited : (16)

References (33)
  • 1
    • 0028952746 scopus 로고
    • Relaxant influence of phosphodiesterase inhibitors in the cat gastric fundus
    • BARBIER, A.J. & LEFEBVRE, R.A (1995). Relaxant influence of phosphodiesterase inhibitors in the cat gastric fundus. Eur. J. Pharmacol., 276, 41-47.
    • (1995) Eur. J. Pharmacol. , vol.276 , pp. 41-47
    • Barbier, A.J.1    Lefebvre, R.A.2
  • 2
    • 9544234649 scopus 로고
    • Smooth muscle cyclic GMP (cGMP) is elevated by activating enteric neurones in the lower esophageal sphincter (LES) muscle of three species
    • BARNETTE, M.S., BARONE, F.C., GROUSE, M., TORPHY, T.J. & ORMSBEE III, H.S. (1988). Smooth muscle cyclic GMP (cGMP) is elevated by activating enteric neurones in the lower esophageal sphincter (LES) muscle of three species. Gastroenterology, 95, 855.
    • (1988) Gastroenterology , vol.95 , pp. 855
    • Barnette, M.S.1    Barone, F.C.2    Grouse, M.3    Torphy, T.J.4    Ormsbee III, H.S.5
  • 3
    • 0025259687 scopus 로고
    • Activation of cyclic AMP-independent protein kinase during canine lower esophageal sphincter relaxation
    • BARNETTE, M.S., GROUSE, M., TORPHY, T.J. & ORMSBEE III, H.S. (1990). Activation of cyclic AMP-independent protein kinase during canine lower esophageal sphincter relaxation. J. Pharmacol. Exp. Ther., 252, 1160-1166.
    • (1990) J. Pharmacol. Exp. Ther. , vol.252 , pp. 1160-1166
    • Barnette, M.S.1    Grouse, M.2    Torphy, T.J.3    Ormsbee III, H.S.4
  • 4
    • 0027717012 scopus 로고
    • Initial biochemical and functional characterization of cyclic nucleotide phosphodiesterase isozymes in canine colonic smooth muscle
    • BARNETTE, M.S., MANNING, C.D., PRICE, W.J. & BARONE, F.C. (1993). Initial biochemical and functional characterization of cyclic nucleotide phosphodiesterase isozymes in canine colonic smooth muscle. J. Pharmacol. Exp. Ther., 264, 801-812.
    • (1993) J. Pharmacol. Exp. Ther. , vol.264 , pp. 801-812
    • Barnette, M.S.1    Manning, C.D.2    Price, W.J.3    Barone, F.C.4
  • 5
    • 0024381077 scopus 로고
    • Cyclic GMP: A potential mediator of neurally-and drug-induced relaxation of opossum lower esophageal sphincter
    • BARNETTE, M.S., TORPHY, T.J., GROUSE, M., FINE, C. & ORMSBEE III, H.S. (1989). Cyclic GMP: A potential mediator of neurally-and drug-induced relaxation of opossum lower esophageal sphincter. J. Pharmacol. Exp. Ther., 249, 524-529.
    • (1989) J. Pharmacol. Exp. Ther. , vol.249 , pp. 524-529
    • Barnette, M.S.1    Torphy, T.J.2    Grouse, M.3    Fine, C.4    Ormsbee III, H.S.5
  • 6
    • 0025215525 scopus 로고
    • Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors
    • BEAVO, J.A. & REIFSNYDER, D.H. (1990). Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. Trends Pharmacol. Sci., 11, 150-155.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 150-155
    • Beavo, J.A.1    Reifsnyder, D.H.2
  • 7
    • 9544231898 scopus 로고
    • AH 21-132 a novel relaxant of airway smooth muscle
    • BEWLEY, J.S. & CHAPMAN, I.D. (1988). AH 21-132 a novel relaxant of airway smooth muscle. Br. J. Pharmacol., 93, 52P.
    • (1988) Br. J. Pharmacol. , vol.93
    • Bewley, J.S.1    Chapman, I.D.2
  • 8
    • 0028074792 scopus 로고
    • Cyclic nucleotide phosphodiesterases in the human lung
    • DENT, G., MAGNUSSEN, M. & RABE, K.F. (1994). Cyclic nucleotide phosphodiesterases in the human lung. Lung, 172, 129-146.
    • (1994) Lung , vol.172 , pp. 129-146
    • Dent, G.1    Magnussen, M.2    Rabe, K.F.3
  • 9
    • 0025985494 scopus 로고
    • Putative substrates for cyclic nucleotide-dependent protein kinases and the control of airway smooth muscle tone
    • GIEMBYCZ, M.A. & RAEBURN, D. (1991). Putative substrates for cyclic nucleotide-dependent protein kinases and the control of airway smooth muscle tone. J. Auton. Pharmacol., 11, 365-398.
    • (1991) J. Auton. Pharmacol. , vol.11 , pp. 365-398
    • Giembycz, M.A.1    Raeburn, D.2
  • 10
    • 0021206792 scopus 로고
    • Characterization of β-adrenoceptors mediating relaxation of the guinea pig ileum
    • GRASSBY, P.F. & BROADLEY, K.J. (1984). Characterization of β-adrenoceptors mediating relaxation of the guinea pig ileum. J. Pharm. Pharmacol., 36, 602-607.
    • (1984) J. Pharm. Pharmacol. , vol.36 , pp. 602-607
    • Grassby, P.F.1    Broadley, K.J.2
  • 11
    • 0026080867 scopus 로고
    • Change in intracellular cyclic nucleotide content accompanies relaxation of the isolated canine internal and anal sphincter
    • GROUSE, M., JOSLYN, A.F., THOMPSON, W. & BARNETTE, M.S.(1991). Change in intracellular cyclic nucleotide content accompanies relaxation of the isolated canine internal and anal sphincter. J. Gastrointest. Motil., 3, 46-52.
    • (1991) J. Gastrointest. Motil. , vol.3 , pp. 46-52
    • Grouse, M.1    Joslyn, A.F.2    Thompson, W.3    Barnette, M.S.4
  • 14
    • 9544227599 scopus 로고
    • Relaxation of guinea-pig proximal colon (PC) and taenia coli (TC) smooth muscle is regulated by cyclic nucleotide (CN) content
    • JOSLYN, A.F., FUDGE, M., BARNETTE, M.S., MANNING, C.D., BARONE, F.C. & ORMSBEE III, H.S. (1988). Relaxation of guinea-pig proximal colon (PC) and taenia coli (TC) smooth muscle is regulated by cyclic nucleotide (CN) content. Gastroenterology, 94, A212.
    • (1988) Gastroenterology , vol.94
    • Joslyn, A.F.1    Fudge, M.2    Barnette, M.S.3    Manning, C.D.4    Barone, F.C.5    Ormsbee III, H.S.6
  • 15
    • 0344124722 scopus 로고
    • Anti-inflammatory effects of novel selective cyclic nucleotide phosphodiesterase inhibitors
    • ed. Jolles, G., Karlsson, J-A. & Taylor, J. London: Academic Press Ltd
    • KARLSSON, J-A., SOUNESS, J., RAEBURN, D., PALFREYMAN, M. & ASHTON, M. (1993). Anti-inflammatory effects of novel selective cyclic nucleotide phosphodiesterase inhibitors. In T-Lymphocyte and Inflammatory Cell Research in Asthma, ed. Jolles, G., Karlsson, J-A. & Taylor, J. pp. 323-351. London: Academic Press Ltd.
    • (1993) T-Lymphocyte and Inflammatory Cell Research in Asthma , pp. 323-351
    • Karlsson, J.-A.1    Souness, J.2    Raeburn, D.3    Palfreyman, M.4    Ashton, M.5
  • 18
    • 0024988252 scopus 로고
    • Cyclic AMP and mechanisms of vasodilation
    • MURRAY, K.J. (1990). Cyclic AMP and mechanisms of vasodilation. Pharmacol. Ther., 47, 329-345.
    • (1990) Pharmacol. Ther. , vol.47 , pp. 329-345
    • Murray, K.J.1
  • 19
    • 0025332303 scopus 로고
    • Pharmacology of nootropics and metabolically active compounds in relation to their use in dementia
    • NICHOLSON, C.D. (1990). Pharmacology of nootropics and metabolically active compounds in relation to their use in dementia. Psychopharmacology, 101, 147-159.
    • (1990) Psychopharmacology , vol.101 , pp. 147-159
    • Nicholson, C.D.1
  • 20
    • 0026008409 scopus 로고
    • Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes
    • NICHOLSON, C.D. & CHALLISS, R.A.J. (1991). Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes. Trends. Pharmacol. Sci., 12, 19-27.
    • (1991) Trends. Pharmacol. Sci. , vol.12 , pp. 19-27
    • Nicholson, C.D.1    Challiss, R.A.J.2
  • 21
    • 0028314313 scopus 로고
    • Inhibitors of cyclic nucleotide phosphodiesterase isoenzymes-their potential utility in the therapy of asthma
    • NICHOLSON, C.D. & SHAHID, M. (1994). Inhibitors of cyclic nucleotide phosphodiesterase isoenzymes-their potential utility in the therapy of asthma. Pulm. Pharmacol., 7, 1-17.
    • (1994) Pulm. Pharmacol. , vol.7 , pp. 1-17
    • Nicholson, C.D.1    Shahid, M.2
  • 22
    • 0027468121 scopus 로고
    • Anti-arrythmic effects of selective inhibition of myocardial phosphodiesterase II
    • PODZUWEIT, T. & MULLER, A. (1993). Anti-arrythmic effects of selective inhibition of myocardial phosphodiesterase II. Lancet, 341, 760.
    • (1993) Lancet , vol.341 , pp. 760
    • Podzuweit, T.1    Muller, A.2
  • 23
    • 0027267644 scopus 로고
    • Isozyme-selective cyclic nucleotide phosphodiesterase inhibitors: Biochemistry, pharmacology and therapeutic potential in asthma
    • RAEBURN, D., SOUNESS, J.E., TOMKINSON, A. & KARLSSON, J-A. (1993). Isozyme-selective cyclic nucleotide phosphodiesterase inhibitors: Biochemistry, pharmacology and therapeutic potential in asthma. Progress Drug Res., 40, 9-32.
    • (1993) Progress Drug Res. , vol.40 , pp. 9-32
    • Raeburn, D.1    Souness, J.E.2    Tomkinson, A.3    Karlsson, J.-A.4
  • 24
    • 0024554484 scopus 로고
    • Influence of stimulators and inhibitors of cyclic nucleotides on lower esophageal sphincter
    • RATTAN, S. & MOUMMI, C. (1989). Influence of stimulators and inhibitors of cyclic nucleotides on lower esophageal sphincter. J. Pharmacol. Exp. Ther., 248, 703-709.
    • (1989) J. Pharmacol. Exp. Ther. , vol.248 , pp. 703-709
    • Rattan, S.1    Moummi, C.2
  • 26
    • 0024835053 scopus 로고
    • Inhibitory effects of AH21-132 in guinea pig isolated ileum and taenia caeci
    • SMALL, R.C., BOYLE, J.P., ELLIOTT, K.R.F., FOSTER, R.W. & WATT, A.J. (1989b). Inhibitory effects of AH21-132 in guinea pig isolated ileum and taenia caeci. Br. J. Pharmacol., 97, 1174-1181.
    • (1989) Br. J. Pharmacol. , vol.97 , pp. 1174-1181
    • Small, R.C.1    Boyle, J.P.2    Elliott, K.R.F.3    Foster, R.W.4    Watt, A.J.5
  • 27
    • 0026455828 scopus 로고
    • Relaxant effects of various xanthine derivatives: Relationship to cyclic nucleotide phosphodiesterase inhibition
    • ed. Strada, S.J. & Hidaka, H. New York: Raven Press Ltd.
    • TAKAGI, K., OGAWA, K., TANAKA, H., SATAKE, T., WATANABE, Y., CHIJIWA, T. & HIDAKA, H. (1992). Relaxant effects of various xanthine derivatives: Relationship to cyclic nucleotide phosphodiesterase inhibition. In Advances in Second Messenger and Phosphoprotein Research Vol., 25, ed. Strada, S.J. & Hidaka, H. New York: Raven Press Ltd.
    • (1992) Advances in Second Messenger and Phosphoprotein Research , vol.25
    • Takagi, K.1    Ogawa, K.2    Tanaka, H.3    Satake, T.4    Watanabe, Y.5    Chijiwa, T.6    Hidaka, H.7
  • 28
    • 0025999955 scopus 로고
    • Cyclic nucleotide phosphodiesterases: Pharmacology, biochemistry and function
    • THOMPSON, W.J. (1991). Cyclic nucleotide phosphodiesterases: Pharmacology, biochemistry and function. Pharmacol. Ther., 51, 13-33.
    • (1991) Pharmacol. Ther. , vol.51 , pp. 13-33
    • Thompson, W.J.1
  • 29
    • 0027454998 scopus 로고
    • Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing β-adrenoceptor subtypes
    • TOMKINSON, A., KARLSSON, J-A. & RAEBURN, D. (1993). Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing β-adrenoceptor subtypes. Br. J. Pharmacol., 108, 57-61.
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 57-61
    • Tomkinson, A.1    Karlsson, J.-A.2    Raeburn, D.3
  • 30
    • 85035176497 scopus 로고
    • The effect of isozyme selective phosphodiesterase inhibitors on methacholine-induced contraction of guinea-pig ileum
    • TOMKINSON, A. & RAEBURN, D. (1995). The effect of isozyme selective phosphodiesterase inhibitors on methacholine-induced contraction of guinea-pig ileum. Br. J. Pharmacol., 114, 437P.
    • (1995) Br. J. Pharmacol. , vol.114
    • Tomkinson, A.1    Raeburn, D.2
  • 31
    • 0027463184 scopus 로고
    • Adenosine receptor-blocking xanthines as inhibitors of phosphodiesterase isozymes
    • UKENA, D., SCHUDT, C. & SYBRECHT, G.W. (1993). Adenosine receptor-blocking xanthines as inhibitors of phosphodiesterase isozymes. Biochem. Pharmacol., 45, 847-851.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 847-851
    • Ukena, D.1    Schudt, C.2    Sybrecht, G.W.3
  • 32
    • 0028289793 scopus 로고
    • Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea-pigs
    • UNDERWOOD, D.C., KOTZER, C.J., BOCHNOWICZ, S., OSBORN, R.T., LUTTMANN, M.A., HAY, D.W.P. & TORPHY, T.J. (1994). Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea-pigs. J. Pharmacol. Exp. Ther., 270, 250-259.
    • (1994) J. Pharmacol. Exp. Ther. , vol.270 , pp. 250-259
    • Underwood, D.C.1    Kotzer, C.J.2    Bochnowicz, S.3    Osborn, R.T.4    Luttmann, M.A.5    Hay, D.W.P.6    Torphy, T.J.7
  • 33
    • 0023607527 scopus 로고
    • Cyclic GMP synthesis and function
    • WALDMAN, S.A. & MURAD, F. (1987). Cyclic GMP synthesis and function. Pharmacol. Rev., 39, 163-196.
    • (1987) Pharmacol. Rev. , vol.39 , pp. 163-196
    • Waldman, S.A.1    Murad, F.2


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