Foot and mouth disease leader protease (Lb pro): Investigation of prime side specificity allows the synthesis of a potent inhibitor

Biochimie

Volumn 94, Issue 3, 2012, Pages 711-718

  Nogueira Santos, Jorge Alexandre ^a   Assis, Diego M ^a   Gouvea, Iuri Estrada ^a   Júdice, Wagner A S ^b   Izidoro, Mario Augusto ^a   Juliano, Maria Aparecida ^a   Skern, Tim ^c   Juliano, Luiz ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSIDADE DE MOGI DAS CRUZES   (Brazil)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Cathepsin; Cysteine protease; Fluorescent peptides; Picornavirus; Protease inhibitors

Indexed keywords

CATHEPSIN K; CATHEPSIN L; CATHEPSIN S; CATHEPSIN V; CYSTEINE PEPTIDASE; DIPEPTIDE; INITIATION FACTOR 4G; PAPAIN; PEPTIDASE; POLYPEPTIDE; PROLINE; PROTEINASE INHIBITOR; SIGNAL PEPTIDASE; SIGNAL PEPTIDASE INHIBITOR; SODIUM CHLORIDE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SPECIFICITY; FOOT AND MOUTH DISEASE VIRUS; PROTEIN CLEAVAGE; VIRUS REPLICATION;

ANIMALS; CATHEPSINS; CYSTEINE PROTEASES; EUKARYOTIC INITIATION FACTOR-4G; FOOT-AND-MOUTH DISEASE; PROTEASE INHIBITORS;

EUKARYOTA; FOOT-AND-MOUTH DISEASE VIRUS; PICORNAVIRIDAE;

EID: 84857046485     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2011.10.016     Document Type: Article

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