Low concentrations of nicotine differentially desensitize nicotinic acetylcholine receptors that include α5 or α6 subunits and that mediate synaptosomal neurotransmitter release

Neuropharmacology

Volumn 62, Issue 5-6, 2012, Pages 1935-1943

  Grady, Sharon R ^a   Wageman, Charles R ^a   Patzlaff, Natalie E ^a,b   Marks, Michael J ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Chrna5 subunit; Chrna6 subunit; Desensitization; Dopamine; GABA; Nicotine

Indexed keywords

NEUROTRANSMITTER; NICOTINE; NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA 5; NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA 6; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; DOPAMINERGIC TRANSMISSION; MOUSE; NERVE ENDING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; SYNAPTOSOME;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MICE, KNOCKOUT; NICOTINE; NICOTINIC AGONISTS; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC; SYNAPTIC TRANSMISSION; SYNAPTOSOMES;

EID: 84857038989     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.12.026     Document Type: Article

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